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The map label for this gene is coaA

Identifier: 157368518

GI number: 157368518

Start: 306179

End: 307129

Strand: Reverse

Name: coaA

Synonym: Spro_0269

Alternate gene names: 157368518

Gene position: 307129-306179 (Counterclockwise)

Preceding gene: 157368528

Following gene: 157368510

Centisome position: 5.64

GC content: 44.79

Gene sequence:

>951_bases
ATGATAAAAAGAGATCAATCTTTAGCGACGCCCTATCTTCAGTTCGATCGTACCCAGTGGGCTGCGTTACGGGATTCGGT
GCCGCTGACACTGTCAGAAGAAGAGATTGTTAAACTGAAAGGGATTAACGAAGATCTCTCTTTGGAAGAGGTAGCACAGA
TTTATCTGCCGCTATCCCGATTGTTGAACTTCTATATCAGTTCGAACCTGCGCCGTCAGGCCGTACTTGAGCAATTTCTC
GGTACCGATGGACAAAAAATCCCCTACGTTATCGGCATTGCCGGCAGCGTTGCCGTAGGTAAAAGTACCACGGCACGTTT
GCTACAGGCATTGCTTAGCAGTTGGCCGGAACATCGTAGCGTTGAGTTGATCACCACCGACGGTTTCCTGCATCCGAATA
AGGTGTTGAACGAACGCGGGCTGATGAAGAAAAAAGGCTTCCCACAGTCTTATGATATGCACAGCCTGGTGAAATTTGTT
TCTGAAGTGAAATCAGGCGCTAAGCGCGTGACCGCTCCGGTCTATTCCCATCTGATTTACGATGTTGTTCCCGAAGGGAA
TAAAGTCATCGAGCAGCCGGATATTCTTATTCTTGAAGGGCTGAACGTATTACAGAGCGGAATGGATTACCCTCACGATC
CGCATCGTGTATTTGTTTCTGACTTTGTTGATTTTTCAATATATGTCGACGCACCTGAAGAACTGCTGCAATCCTGGTAT
ATCAATAGATTTCTTAAGTTCCGTCAGGGTGCATTTTCCAATCCTGACTCTTATTTCCATAACTATTCCAAGTTACCTGA
ACCAGAAGCTATAAATATAGCATCTCAACTATGGAATGAGATTAATGGATTGAATTTACAAGAAAATATCTTACCCACAC
GCGAACGCGCCAGTCTGATCATGACGAAGAGTGCTAATCACGCGGTTGAAAACGTACGTTTAAGAAAATAA

Upstream 100 bases:

>100_bases
ACGTCAAAAACGAAGCTGTCTATAATATGCAGCTTGATTATTATCTGGAGTTGGCGTCCGGCGCCTTTCCCAACCTGCGT
TAACAGGCAGAATTTGGCTT

Downstream 100 bases:

>100_bases
TTTAATAATAAGCAGGGGCCTACCGGCCCCTTATATTTAATGATAATTACTCGGCGCTGCGTAGAGAGATTTCCCCACCA
ATGAACGGTTTAATCACACC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIKRDQSLATPYLQFDRTQWAALRDSVPLTLSEEEIVKLKGINEDLSLEEVAQIYLPLSRLLNFYISSNLRRQAVLEQFL
GTDGQKIPYVIGIAGSVAVGKSTTARLLQALLSSWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPQSYDMHSLVKFV
SEVKSGAKRVTAPVYSHLIYDVVPEGNKVIEQPDILILEGLNVLQSGMDYPHDPHRVFVSDFVDFSIYVDAPEELLQSWY
INRFLKFRQGAFSNPDSYFHNYSKLPEPEAINIASQLWNEINGLNLQENILPTRERASLIMTKSANHAVENVRLRK

Sequences:

>Translated_316_residues
MIKRDQSLATPYLQFDRTQWAALRDSVPLTLSEEEIVKLKGINEDLSLEEVAQIYLPLSRLLNFYISSNLRRQAVLEQFL
GTDGQKIPYVIGIAGSVAVGKSTTARLLQALLSSWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPQSYDMHSLVKFV
SEVKSGAKRVTAPVYSHLIYDVVPEGNKVIEQPDILILEGLNVLQSGMDYPHDPHRVFVSDFVDFSIYVDAPEELLQSWY
INRFLKFRQGAFSNPDSYFHNYSKLPEPEAINIASQLWNEINGLNLQENILPTRERASLIMTKSANHAVENVRLRK
>Mature_316_residues
MIKRDQSLATPYLQFDRTQWAALRDSVPLTLSEEEIVKLKGINEDLSLEEVAQIYLPLSRLLNFYISSNLRRQAVLEQFL
GTDGQKIPYVIGIAGSVAVGKSTTARLLQALLSSWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPQSYDMHSLVKFV
SEVKSGAKRVTAPVYSHLIYDVVPEGNKVIEQPDILILEGLNVLQSGMDYPHDPHRVFVSDFVDFSIYVDAPEELLQSWY
INRFLKFRQGAFSNPDSYFHNYSKLPEPEAINIASQLWNEINGLNLQENILPTRERASLIMTKSANHAVENVRLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=316, Percent_Identity=82.9113924050633, Blast_Score=554, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_SERP5 (A8G8D9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476507.1
- ProteinModelPortal:   A8G8D9
- SMR:   A8G8D9
- STRING:   A8G8D9
- GeneID:   5606919
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0269
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   SPRO399741:SPRO_0269-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35956; Mature: 35956

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRDQSLATPYLQFDRTQWAALRDSVPLTLSEEEIVKLKGINEDLSLEEVAQIYLPLSR
CCCCCCHHCCCHHHHCCHHHHHHHCCCCCEECHHHHHEEECCCCCCCHHHHHHHHHHHHH
LLNFYISSNLRRQAVLEQFLGTDGQKIPYVIGIAGSVAVGKSTTARLLQALLSSWPEHRS
HHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCC
VELITTDGFLHPNKVLNERGLMKKKGFPQSYDMHSLVKFVSEVKSGAKRVTAPVYSHLIY
EEEEEECCCCCCHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVVPEGNKVIEQPDILILEGLNVLQSGMDYPHDPHRVFVSDFVDFSIYVDAPEELLQSWY
HHCCCCCCEECCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCEEEEEECCHHHHHHHHH
INRFLKFRQGAFSNPDSYFHNYSKLPEPEAINIASQLWNEINGLNLQENILPTRERASLI
HHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHEE
MTKSANHAVENVRLRK
EECCCHHHHHHCCCCC
>Mature Secondary Structure
MIKRDQSLATPYLQFDRTQWAALRDSVPLTLSEEEIVKLKGINEDLSLEEVAQIYLPLSR
CCCCCCHHCCCHHHHCCHHHHHHHCCCCCEECHHHHHEEECCCCCCCHHHHHHHHHHHHH
LLNFYISSNLRRQAVLEQFLGTDGQKIPYVIGIAGSVAVGKSTTARLLQALLSSWPEHRS
HHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCC
VELITTDGFLHPNKVLNERGLMKKKGFPQSYDMHSLVKFVSEVKSGAKRVTAPVYSHLIY
EEEEEECCCCCCHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVVPEGNKVIEQPDILILEGLNVLQSGMDYPHDPHRVFVSDFVDFSIYVDAPEELLQSWY
HHCCCCCCEECCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCEEEEEECCHHHHHHHHH
INRFLKFRQGAFSNPDSYFHNYSKLPEPEAINIASQLWNEINGLNLQENILPTRERASLI
HHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHEE
MTKSANHAVENVRLRK
EECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA