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The map label for this gene is yifK [H]

Identifier: 157368422

GI number: 157368422

Start: 195448

End: 196851

Strand: Direct

Name: yifK [H]

Synonym: Spro_0173

Alternate gene names: 157368422

Gene position: 195448-196851 (Clockwise)

Preceding gene: 157368421

Following gene: 157368428

Centisome position: 3.59

GC content: 55.41

Gene sequence:

>1404_bases
ATGCCACACACTGAAAAACCGCAAGGACTACACCGGGGGCTGGAAGCCCGGCATATCGAGCTGATTGCTCTGGGCGGCAC
CATTGGCGTTGGCCTGTTTATGGGCTCGGCCAGCACGCTGAAATGGGCGGGGCCGTCGGTATTATTGGCTTATATCATCG
CCGGGCTGTTCGTGTTCTTTATTATGCGTTCGATGGGCGAGATGCTGTTCCTTGAACCGGTCGCAGGCTCCTTTGCCGTT
TATGCACATAAATACATGAGTCCTTACTTTGGCTATCTGACGGCCTGGGGCTATTGGTTTATGTGGATTGCCGTCGGCAT
CTCGGAAATTACCGCCATTGGGGTCTACGTGCAGTTCTGGTTCCCGGAGATCCCGCAGTGGCTGCCGGCGCTGATCGCGG
TGGCGATGGTAGCGCTGGCTAACGTGGCGGCGGTACGCCTGTACGGCGAGCTGGAGTTTTGGTTTGCCATGATTAAGGTG
ACCACCATCATTGTGATGATTCTGGTGGGGCTGGGGGTGATCCTGTTTGGCTTTGGCAATGGGGGGCAGCCTATCGGTTT
TGCCAACCTGACCGAGCACGGCGGTTTCTTTGCCGGCGGCTGGAAGGGCTTCCTGTTTGCGCTGTGTATTGTCGTGGCGT
CCTATCAGGGGGTTGAGCTGGTCGGTATTACCGCCGGTGAGGCCAAGAACCCGCAGGTGACGCTGAAACGCGCGATTAAC
AACATCCTGTGGCGCATCCTGATCTTCTACGTCGGCGCTATTTTTGTCATTGTCACCATCTTCCCATGGAACGGTATCGG
CACCACCGGCAGCCCATTTGTACTGACCTTTGCCAAAATCGGCATCGTTGCCGCTGCCGGTATCATTAACTTCGTGGTGT
TGACCGCTGCACTCTCTGGCTGCAATAGCGGTATGTATAGCGGGGGGCGCATGCTGTATGCGCTGGCCAAAAACCGTCAA
CTCCCTGCCTCACTGACCAGGCTGTCTGCCAACGGCGTGCCGGTGAACTGTATTGCCGTGACCATCGCCTGTCTGTTGGT
CGGCTCTGGCCTGAATTATCTGATCCCCAATCCGCAGGCGGTATTTGTCTATGTCTACAGCGCCAGCGTGCTGCCGGGTA
TGGTGCCGTGGTTTGTGGTGCTGATTAGCCAGCTGTATTTCCGCCGAGCCCATAAGGAAGCGCTCAAAACCCACAGCTTT
AAGTCGATCATGTTCCCCTATGTGAACTATCTGACCATCGCTTTTCTGGTCTGCGTGCTGATCGGCATGGGAATTAACCC
GGATACTCGTATTTCTTTGCTGGTTGGGGCGATATTCTTGGCGGCAGTCAGCCTGTGCTACTTTGTTTTCGGGATGCACA
AGAAACATCATCCGGCTGAAAAACGGACAGAAACCCAGCAATAA

Upstream 100 bases:

>100_bases
CTGAGCGGCGGGAGATGATTTGCGCTATTTTTCATTAAAACAATAACGACCGGTAACGGCCGGCATGCAGACACAATCAA
AAGAATATTATCGAGGATTT

Downstream 100 bases:

>100_bases
CCGGTGAAAAGGGGCTACGGATAGCCCTTTCCTGCGCGGGACTGAGCAAAGCGTAATCAAACGCGACATTTCTGCGAAAA
AGCACTAGACAGGATTGGGT

Product: putative transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MPHTEKPQGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVAGSFAV
YAHKYMSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFWFPEIPQWLPALIAVAMVALANVAAVRLYGELEFWFAMIKV
TTIIVMILVGLGVILFGFGNGGQPIGFANLTEHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEAKNPQVTLKRAIN
NILWRILIFYVGAIFVIVTIFPWNGIGTTGSPFVLTFAKIGIVAAAGIINFVVLTAALSGCNSGMYSGGRMLYALAKNRQ
LPASLTRLSANGVPVNCIAVTIACLLVGSGLNYLIPNPQAVFVYVYSASVLPGMVPWFVVLISQLYFRRAHKEALKTHSF
KSIMFPYVNYLTIAFLVCVLIGMGINPDTRISLLVGAIFLAAVSLCYFVFGMHKKHHPAEKRTETQQ

Sequences:

>Translated_467_residues
MPHTEKPQGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVAGSFAV
YAHKYMSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFWFPEIPQWLPALIAVAMVALANVAAVRLYGELEFWFAMIKV
TTIIVMILVGLGVILFGFGNGGQPIGFANLTEHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEAKNPQVTLKRAIN
NILWRILIFYVGAIFVIVTIFPWNGIGTTGSPFVLTFAKIGIVAAAGIINFVVLTAALSGCNSGMYSGGRMLYALAKNRQ
LPASLTRLSANGVPVNCIAVTIACLLVGSGLNYLIPNPQAVFVYVYSASVLPGMVPWFVVLISQLYFRRAHKEALKTHSF
KSIMFPYVNYLTIAFLVCVLIGMGINPDTRISLLVGAIFLAAVSLCYFVFGMHKKHHPAEKRTETQQ
>Mature_466_residues
PHTEKPQGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVAGSFAVY
AHKYMSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFWFPEIPQWLPALIAVAMVALANVAAVRLYGELEFWFAMIKVT
TIIVMILVGLGVILFGFGNGGQPIGFANLTEHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEAKNPQVTLKRAINN
ILWRILIFYVGAIFVIVTIFPWNGIGTTGSPFVLTFAKIGIVAAAGIINFVVLTAALSGCNSGMYSGGRMLYALAKNRQL
PASLTRLSANGVPVNCIAVTIACLLVGSGLNYLIPNPQAVFVYVYSASVLPGMVPWFVVLISQLYFRRAHKEALKTHSFK
SIMFPYVNYLTIAFLVCVLIGMGINPDTRISLLVGAIFLAAVSLCYFVFGMHKKHHPAEKRTETQQ

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=81.3449023861171, Blast_Score=730, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=429, Percent_Identity=42.8904428904429, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1786302, Length=452, Percent_Identity=40.4867256637168, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1786602, Length=457, Percent_Identity=44.4201312910284, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1790653, Length=456, Percent_Identity=39.4736842105263, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI87081708, Length=476, Percent_Identity=35.9243697478992, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1788480, Length=439, Percent_Identity=38.9521640091116, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI87081915, Length=473, Percent_Identity=36.7864693446089, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1789017, Length=436, Percent_Identity=32.5688073394495, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI2367353, Length=454, Percent_Identity=24.4493392070485, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=440, Percent_Identity=35.2272727272727, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6320772, Length=439, Percent_Identity=33.4851936218679, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6324924, Length=415, Percent_Identity=32.289156626506, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=447, Percent_Identity=31.9910514541387, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324990, Length=446, Percent_Identity=30.7174887892377, Blast_Score=180, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6322892, Length=412, Percent_Identity=31.3106796116505, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321629, Length=400, Percent_Identity=29.5, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319608, Length=432, Percent_Identity=28.0092592592593, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6321053, Length=421, Percent_Identity=28.5035629453682, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322967, Length=405, Percent_Identity=26.9135802469136, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319824, Length=415, Percent_Identity=27.9518072289157, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319542, Length=401, Percent_Identity=27.431421446384, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6319543, Length=401, Percent_Identity=26.9326683291771, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6324553, Length=403, Percent_Identity=29.2803970223325, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=398, Percent_Identity=27.3869346733668, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324981, Length=413, Percent_Identity=27.6029055690073, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320717, Length=406, Percent_Identity=23.8916256157635, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6320364, Length=496, Percent_Identity=23.5887096774194, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50830; Mature: 50699

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTEKPQGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFF
CCCCCCCCHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IMRSMGEMLFLEPVAGSFAVYAHKYMSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFW
HHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPEIPQWLPALIAVAMVALANVAAVRLYGELEFWFAMIKVTTIIVMILVGLGVILFGFGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GGQPIGFANLTEHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEAKNPQVTLKRAIN
CCCCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
NILWRILIFYVGAIFVIVTIFPWNGIGTTGSPFVLTFAKIGIVAAAGIINFVVLTAALSG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CNSGMYSGGRMLYALAKNRQLPASLTRLSANGVPVNCIAVTIACLLVGSGLNYLIPNPQA
CCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCE
VFVYVYSASVLPGMVPWFVVLISQLYFRRAHKEALKTHSFKSIMFPYVNYLTIAFLVCVL
EEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGMGINPDTRISLLVGAIFLAAVSLCYFVFGMHKKHHPAEKRTETQQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
>Mature Secondary Structure 
PHTEKPQGLHRGLEARHIELIALGGTIGVGLFMGSASTLKWAGPSVLLAYIIAGLFVFF
CCCCCCCHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IMRSMGEMLFLEPVAGSFAVYAHKYMSPYFGYLTAWGYWFMWIAVGISEITAIGVYVQFW
HHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPEIPQWLPALIAVAMVALANVAAVRLYGELEFWFAMIKVTTIIVMILVGLGVILFGFGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GGQPIGFANLTEHGGFFAGGWKGFLFALCIVVASYQGVELVGITAGEAKNPQVTLKRAIN
CCCCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
NILWRILIFYVGAIFVIVTIFPWNGIGTTGSPFVLTFAKIGIVAAAGIINFVVLTAALSG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CNSGMYSGGRMLYALAKNRQLPASLTRLSANGVPVNCIAVTIACLLVGSGLNYLIPNPQA
CCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCE
VFVYVYSASVLPGMVPWFVVLISQLYFRRAHKEALKTHSFKSIMFPYVNYLTIAFLVCVL
EEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGMGINPDTRISLLVGAIFLAAVSLCYFVFGMHKKHHPAEKRTETQQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]