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The map label for this gene is lrhA [H]

Identifier: 157368354

GI number: 157368354

Start: 112502

End: 113356

Strand: Reverse

Name: lrhA [H]

Synonym: Spro_0105

Alternate gene names: 157368354

Gene position: 113356-112502 (Counterclockwise)

Preceding gene: 157368359

Following gene: 157368347

Centisome position: 2.08

GC content: 63.86

Gene sequence:

>855_bases
ATGAATCGTTACCCGATGTTCAATCCGCAGTTACTGCTCAGCTTTGTCGCAGTATGCGACAGCAACAGCTTCACTCGCGC
CGCAGAGCGGGTATTTTTGTCGCAGTCGACCGTCAGCCAACAGGTGCGCCGCTTGGAAGAAATGCTGGGTAAACCCCTGT
TTGAACGTTCGTCCCATCAGGTACTGCTGACCGAGGAAGGCGTCAAGCTGTTGAGCTATGCGCGGCGCATCATCGCGCTG
AATGAAGAGGCGCACGACGCCTTGACCGGCATCTGGCGCGACGGCGTACTACGGTTGGGGATGCCGGAGGATTTTGCCGC
CCCCACCACCGAACTGCTGGCGGAGTTCAGCCGGGCGCATCCGCATCTGCGGCTGGACGTCACCAGCGGCCTGAGCGCCG
ATCTGCACAGTGCCTACGCCCGTGAAGAGCTGGATCTGATCCTGGTTAAACAGCGCCGTAGCCAGCCGCCGCGGGCCGCC
CGGCCGGAACCGCTGCTGTGGCTGGACAGCTTGGCCTTCCCGGCAATAGAACAGTCGCCGGTACCGCTGGCGGTATTCCC
GCTCAATGGGTTATATCGCGATGATTTGTGTCAGGCGCTGGATAACCTCGGCAAGCGCTGGCGTATTGGCTACAGCAGCG
CCAGTCTGGCCGCACTCACCGCCGCATCCGCCGCCGGGCTGGGCGTCACCCTGCTGCCGGCCGGCTGCCGCTTGCCCAGC
CATCGGGTTCTCGGCAGCGCCGAAGGGTTGCCGCCGATCGACAACATTGAGCTGGCGCTGTACTACCGCGACGGCGCCCC
CGCAGCCACTCCCGCGCTGGCCGAACGGCTGAAGGCGTTTTGTGGGTTGGCGTGA

Upstream 100 bases:

>100_bases
AGAGTGCGGGGTCACAGAGTGGCTACCGCAACGTTGCCTTACTCTAGGCTTCCCCGTTAGTATTGGGAAATTAAATAATA
AAATAGCCAACAGTGGAAAA

Downstream 100 bases:

>100_bases
GAAGATTATTCCAAAAATTGCGGATGTTTGAGCTGCAGCCAATCGTTAACCGCCAGCCAGAGTGCGCCTGCCTGCTCCAG
ACAGGCGGACACCGCCGCAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNRYPMFNPQLLLSFVAVCDSNSFTRAAERVFLSQSTVSQQVRRLEEMLGKPLFERSSHQVLLTEEGVKLLSYARRIIAL
NEEAHDALTGIWRDGVLRLGMPEDFAAPTTELLAEFSRAHPHLRLDVTSGLSADLHSAYAREELDLILVKQRRSQPPRAA
RPEPLLWLDSLAFPAIEQSPVPLAVFPLNGLYRDDLCQALDNLGKRWRIGYSSASLAALTAASAAGLGVTLLPAGCRLPS
HRVLGSAEGLPPIDNIELALYYRDGAPAATPALAERLKAFCGLA

Sequences:

>Translated_284_residues
MNRYPMFNPQLLLSFVAVCDSNSFTRAAERVFLSQSTVSQQVRRLEEMLGKPLFERSSHQVLLTEEGVKLLSYARRIIAL
NEEAHDALTGIWRDGVLRLGMPEDFAAPTTELLAEFSRAHPHLRLDVTSGLSADLHSAYAREELDLILVKQRRSQPPRAA
RPEPLLWLDSLAFPAIEQSPVPLAVFPLNGLYRDDLCQALDNLGKRWRIGYSSASLAALTAASAAGLGVTLLPAGCRLPS
HRVLGSAEGLPPIDNIELALYYRDGAPAATPALAERLKAFCGLA
>Mature_284_residues
MNRYPMFNPQLLLSFVAVCDSNSFTRAAERVFLSQSTVSQQVRRLEEMLGKPLFERSSHQVLLTEEGVKLLSYARRIIAL
NEEAHDALTGIWRDGVLRLGMPEDFAAPTTELLAEFSRAHPHLRLDVTSGLSADLHSAYAREELDLILVKQRRSQPPRAA
RPEPLLWLDSLAFPAIEQSPVPLAVFPLNGLYRDDLCQALDNLGKRWRIGYSSASLAALTAASAAGLGVTLLPAGCRLPS
HRVLGSAEGLPPIDNIELALYYRDGAPAATPALAERLKAFCGLA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=267, Percent_Identity=36.3295880149813, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI157672245, Length=174, Percent_Identity=32.183908045977, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=124, Percent_Identity=34.6774193548387, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=28.0936454849498, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=93, Percent_Identity=39.7849462365591, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787589, Length=121, Percent_Identity=36.3636363636364, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31136; Mature: 31136

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYPMFNPQLLLSFVAVCDSNSFTRAAERVFLSQSTVSQQVRRLEEMLGKPLFERSSHQ
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCE
VLLTEEGVKLLSYARRIIALNEEAHDALTGIWRDGVLRLGMPEDFAAPTTELLAEFSRAH
EEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCC
PHLRLDVTSGLSADLHSAYAREELDLILVKQRRSQPPRAARPEPLLWLDSLAFPAIEQSP
CCEEEEECCCCCHHHHHHHHHHHHHHEEEHHHCCCCCCCCCCCCEEEHHHHCCCCCCCCC
VPLAVFPLNGLYRDDLCQALDNLGKRWRIGYSSASLAALTAASAAGLGVTLLPAGCRLPS
CCEEEECCCCCCHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
HRVLGSAEGLPPIDNIELALYYRDGAPAATPALAERLKAFCGLA
CHHCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRYPMFNPQLLLSFVAVCDSNSFTRAAERVFLSQSTVSQQVRRLEEMLGKPLFERSSHQ
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCE
VLLTEEGVKLLSYARRIIALNEEAHDALTGIWRDGVLRLGMPEDFAAPTTELLAEFSRAH
EEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCC
PHLRLDVTSGLSADLHSAYAREELDLILVKQRRSQPPRAARPEPLLWLDSLAFPAIEQSP
CCEEEEECCCCCHHHHHHHHHHHHHHEEEHHHCCCCCCCCCCCCEEEHHHHCCCCCCCCC
VPLAVFPLNGLYRDDLCQALDNLGKRWRIGYSSASLAALTAASAAGLGVTLLPAGCRLPS
CCEEEECCCCCCHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
HRVLGSAEGLPPIDNIELALYYRDGAPAATPALAERLKAFCGLA
CHHCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]