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The map label for this gene is xylA

Identifier: 157368347

GI number: 157368347

Start: 104720

End: 106039

Strand: Reverse

Name: xylA

Synonym: Spro_0098

Alternate gene names: 157368347

Gene position: 106039-104720 (Counterclockwise)

Preceding gene: 157368354

Following gene: 157368346

Centisome position: 1.95

GC content: 57.42

Gene sequence:

>1320_bases
ATGCAATCTTATTTTGATCAGCTTGAGCAAGTGCACTACGAAGGCCCCACCAGTAATAATCCGCTGGCCTTTCATCATTA
CAATCCGGATGAACTGGTGCTCGGCAAGCGCATGGCGGAGCACCTGCGCTTTGCCGCCTGCTACTGGCACACCTTCTGCT
GGAACGGGGCGGACATGTTCGGCGTCGGCTCGTTCGATCGCCCCTGGCAGCAGCCGGGCGACGCGCTGACGTTAGCCAAA
CGTAAGGCCGACGTGGCGTTCGAGTTTTTTCACAAGCTGAACGTTCCCTATTACTGCTTCCATGACGTCGACGTCTCGCC
GGAAGGCGCCTCGCTGAAAGAATACCTGCACAACTTTGCGGTCATGACCGACGTGCTGGAAGAAAAACAACACAGCAGCG
GGGTAAAACTGCTGTGGGGCACCGCCAACTGCTTTACCCATCCGCGTTACGGTGCCGGTGCGGCCACCAACCCGGATCCG
GAAGTCTTCAGTTGGGCGGCTACCCAGGTGTTCACCGCCATGAACGCCACCCAGCGTCTGGGCGGTGAAAACTACGTGCT
TTGGGGCGGCCGCGAAGGCTATGAAACCTTGCTGAATACCGATCTGCGCCAGGAGCGTGAGCAAATTGGCCGCTTTATGC
AGATGGTGGTGGAGCACAAGCACAAAACCGGTTTCCAGGGCACCCTGCTGATCGAGCCAAAACCTCAGGAGCCGACCAAG
CATCAATACGATTACGACGTCGCCACCGTGTACGGCTTCCTCAAGCAGTTTGGCCTGGAGAAAGAGATCAAGGTGAATAT
CGAAGCCAACCACGCCACGCTGGCAGGCCACTCGTTCCACCATGAGATAGCCACCGCCATTGCGCTCGGCATCTTTGGTT
CCGTCGATGCCAACCGGGGCGACCCACAGTTGGGCTGGGATACCGACCAGTTCCCGATCAGCGTGGAAGAGAACGCGCTG
GTGATGTTCGAAATTCTCAAGGCCGGGGGCTTTACCACCGGCGGGCTGAACTTCGATGCCAAGGTACGCCGTCAAAGCAC
CGACAAATACGACCTGTTCTATGGCCATATTGGGGCTATGGATACCATGGCACTGGCGCTGAAGGTCGCGGCTAAAATGG
TGACTGACGGCCAGTTACATCAGCAGGTATCAAAACGCTATGCCGGCTGGAATGGTGAATTGGGCCAGCAAATTTTGCAG
GGCAAACTGTCGCTCGAGGCGCTGGCGCAGTACGCTGAAGGACATGCACTGGCGCCACAGCACGTCAGCGGCCGCCAGGA
ACAGCTTGAAAACCTGATGAACCGCTATCTGTTCGGCTAA

Upstream 100 bases:

>100_bases
CTGTGAATTTAACTGTGAAATAACGTAATTGAGCAGCCTGTCGCAAACTCCGAAGATAAAGCCATCCCGTAAACCGGGCA
TTGCTACCCAGGAGTCGATA

Downstream 100 bases:

>100_bases
CTGACCCCGCGCGGCACTCGCCGCGCCTTTAAGGATCTTTCCATGTATATCGGCATCGACCTCGGCACGTCCGGCGTAAA
AGTCATTTTGCTCAGTGAAC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MQSYFDQLEQVHYEGPTSNNPLAFHHYNPDELVLGKRMAEHLRFAACYWHTFCWNGADMFGVGSFDRPWQQPGDALTLAK
RKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLHNFAVMTDVLEEKQHSSGVKLLWGTANCFTHPRYGAGAATNPDP
EVFSWAATQVFTAMNATQRLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDPQLGWDTDQFPISVEENAL
VMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKVAAKMVTDGQLHQQVSKRYAGWNGELGQQILQ
GKLSLEALAQYAEGHALAPQHVSGRQEQLENLMNRYLFG

Sequences:

>Translated_439_residues
MQSYFDQLEQVHYEGPTSNNPLAFHHYNPDELVLGKRMAEHLRFAACYWHTFCWNGADMFGVGSFDRPWQQPGDALTLAK
RKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLHNFAVMTDVLEEKQHSSGVKLLWGTANCFTHPRYGAGAATNPDP
EVFSWAATQVFTAMNATQRLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDPQLGWDTDQFPISVEENAL
VMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKVAAKMVTDGQLHQQVSKRYAGWNGELGQQILQ
GKLSLEALAQYAEGHALAPQHVSGRQEQLENLMNRYLFG
>Mature_439_residues
MQSYFDQLEQVHYEGPTSNNPLAFHHYNPDELVLGKRMAEHLRFAACYWHTFCWNGADMFGVGSFDRPWQQPGDALTLAK
RKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLHNFAVMTDVLEEKQHSSGVKLLWGTANCFTHPRYGAGAATNPDP
EVFSWAATQVFTAMNATQRLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDPQLGWDTDQFPISVEENAL
VMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKVAAKMVTDGQLHQQVSKRYAGWNGELGQQILQ
GKLSLEALAQYAEGHALAPQHVSGRQEQLENLMNRYLFG

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=438, Percent_Identity=85.6164383561644, Blast_Score=803, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_SERP5 (A8G7W8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476336.1
- ProteinModelPortal:   A8G7W8
- SMR:   A8G7W8
- STRING:   A8G7W8
- GeneID:   5605676
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0098
- eggNOG:   COG2115
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- BioCyc:   SPRO399741:SPRO_0098-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49435; Mature: 49435

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 101-101 ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYFDQLEQVHYEGPTSNNPLAFHHYNPDELVLGKRMAEHLRFAACYWHTFCWNGADMF
CCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVGSFDRPWQQPGDALTLAKRKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLHNFA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHH
VMTDVLEEKQHSSGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATQRL
HHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTK
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DPQLGWDTDQFPISVEENALVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAM
CCCCCCCCCCCCEEECCCCEEEHHHHHHCCCEECCCCCCHHHHHCCCCCEEEEEECHHHH
DTMALALKVAAKMVTDGQLHQQVSKRYAGWNGELGQQILQGKLSLEALAQYAEGHALAPQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
HVSGRQEQLENLMNRYLFG
HCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSYFDQLEQVHYEGPTSNNPLAFHHYNPDELVLGKRMAEHLRFAACYWHTFCWNGADMF
CCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVGSFDRPWQQPGDALTLAKRKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLHNFA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHH
VMTDVLEEKQHSSGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATQRL
HHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTK
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DPQLGWDTDQFPISVEENALVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAM
CCCCCCCCCCCCEEECCCCEEEHHHHHHCCCEECCCCCCHHHHHCCCCCEEEEEECHHHH
DTMALALKVAAKMVTDGQLHQQVSKRYAGWNGELGQQILQGKLSLEALAQYAEGHALAPQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
HVSGRQEQLENLMNRYLFG
HCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA