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The map label for this gene is kdgR [H]

Identifier: 157368310

GI number: 157368310

Start: 61106

End: 62140

Strand: Reverse

Name: kdgR [H]

Synonym: Spro_0061

Alternate gene names: 157368310

Gene position: 62140-61106 (Counterclockwise)

Preceding gene: 157368311

Following gene: 157368309

Centisome position: 1.14

GC content: 58.45

Gene sequence:

>1035_bases
GTGAGCAGTGTTAAGGCAATTCGCGCCTCGGGGCGGGCCACCATCAGCGATGTGGCGAAAACCGCCAAGACGGGTAAAAC
CAGCGTATCGCGCTATCTCAATGGTGAGCAGCACCTGCTTTCTGACGATCTCAAACAGCGCATCGAACAGGCGATCCACC
AGCTCGACTATCGGCCCAGCCAGATGGCACGCAGCCTGAAGGGCGGCCAAACGCGGCTGATTGGCCTGATCATCGCCGAC
ATCACCAATCCCTACTCGGTGGACGTAATGCGCGGTATCGAGGCGGCCTGCCGCCAACACGGTTTTACCCTGCTGGTGTG
TAATACCAATAACGAGGTCAATCAGGAACAGCACTACCTGCAATTGCTTAGCAGTTACCGGGTAGAGGGCATCGTGGTCA
ATGCCGTCGGTATGCGCGAAGAGGCGCTGTCGACCCTGCAACAATCGATGCTGCCGATGGTGCTTATTGACCGCAAAATC
TCTGATTTCGCCTGCGATGTGGTGGGCCTCAACAATCACGAAGCGGCCACCGTCGCCACGGAACACCTGCTGCAACAGGG
TTTCGAAGCCATTTTGTTTCTCAGCGAGCCAATCGGCACGGTCAATACCCGCCTGGAAAGGCTGCACGCCTTTAACCAGA
CCATGGCGCAACATGCCGGACTGTTGGCTGAACAGGCCGAAACTCCGCTTAACGACGTTAAGCAGCTGGAAGGCGTGATC
CGCGACTTTAACGCTCGCCATCGCGGTATGCGCAAGGCGGTGATTTCCGCTAATGGTGCCCTGACGCTGCAGGTGGCACG
CGCCATGCGCCGGCTGGGTATCCAGTGGGGCAGCGATATCGGCCTGCTGGGCTTTGACGAACTGGAATGGGCCGAACTGG
CTGGGGTGGGTATCACTACCCTGAAACAGCCCACCTATCAAATGGGCCATGCCGCGCTGGAGCAACTGGTGCAACGCATT
CAGGGCCTGAATACCCCCATCAGCGAACAGATGTTCCCCGGTGAACTGATCGTGCGCGGCTCCACCACCCGATAA

Upstream 100 bases:

>100_bases
CCCCGCCACTTCCTGTCCTCCGCCGCTCCGCCATTGGGCATTCCGGCTCTGCGCCGGGTGTGTTAGTCTCCTTGGCAATT
AACCACAGGGGAGATCGGCT

Downstream 100 bases:

>100_bases
TCTCTCCCCTTTCCCGCAGGGGCGCGAGCTGTGCGCCCCTTACATCGCATCATTCAGACTATTTTTTGCTCAGGTTCGTG
ACTGCGATCATATTTTTACA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSSVKAIRASGRATISDVAKTAKTGKTSVSRYLNGEQHLLSDDLKQRIEQAIHQLDYRPSQMARSLKGGQTRLIGLIIAD
ITNPYSVDVMRGIEAACRQHGFTLLVCNTNNEVNQEQHYLQLLSSYRVEGIVVNAVGMREEALSTLQQSMLPMVLIDRKI
SDFACDVVGLNNHEAATVATEHLLQQGFEAILFLSEPIGTVNTRLERLHAFNQTMAQHAGLLAEQAETPLNDVKQLEGVI
RDFNARHRGMRKAVISANGALTLQVARAMRRLGIQWGSDIGLLGFDELEWAELAGVGITTLKQPTYQMGHAALEQLVQRI
QGLNTPISEQMFPGELIVRGSTTR

Sequences:

>Translated_344_residues
MSSVKAIRASGRATISDVAKTAKTGKTSVSRYLNGEQHLLSDDLKQRIEQAIHQLDYRPSQMARSLKGGQTRLIGLIIAD
ITNPYSVDVMRGIEAACRQHGFTLLVCNTNNEVNQEQHYLQLLSSYRVEGIVVNAVGMREEALSTLQQSMLPMVLIDRKI
SDFACDVVGLNNHEAATVATEHLLQQGFEAILFLSEPIGTVNTRLERLHAFNQTMAQHAGLLAEQAETPLNDVKQLEGVI
RDFNARHRGMRKAVISANGALTLQVARAMRRLGIQWGSDIGLLGFDELEWAELAGVGITTLKQPTYQMGHAALEQLVQRI
QGLNTPISEQMFPGELIVRGSTTR
>Mature_343_residues
SSVKAIRASGRATISDVAKTAKTGKTSVSRYLNGEQHLLSDDLKQRIEQAIHQLDYRPSQMARSLKGGQTRLIGLIIADI
TNPYSVDVMRGIEAACRQHGFTLLVCNTNNEVNQEQHYLQLLSSYRVEGIVVNAVGMREEALSTLQQSMLPMVLIDRKIS
DFACDVVGLNNHEAATVATEHLLQQGFEAILFLSEPIGTVNTRLERLHAFNQTMAQHAGLLAEQAETPLNDVKQLEGVIR
DFNARHRGMRKAVISANGALTLQVARAMRRLGIQWGSDIGLLGFDELEWAELAGVGITTLKQPTYQMGHAALEQLVQRIQ
GLNTPISEQMFPGELIVRGSTTR

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=29.2452830188679, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1790369, Length=348, Percent_Identity=25.2873563218391, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787948, Length=322, Percent_Identity=28.2608695652174, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=25.9818731117825, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=25.752508361204, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789068, Length=339, Percent_Identity=23.0088495575221, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI48994940, Length=319, Percent_Identity=25.3918495297806, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=25.2252252252252, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787906, Length=341, Percent_Identity=22.8739002932551, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=22.3241590214067, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786268, Length=184, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=20.9230769230769, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790689, Length=201, Percent_Identity=25.8706467661692, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37935; Mature: 37804

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVKAIRASGRATISDVAKTAKTGKTSVSRYLNGEQHLLSDDLKQRIEQAIHQLDYRPS
CCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
QMARSLKGGQTRLIGLIIADITNPYSVDVMRGIEAACRQHGFTLLVCNTNNEVNQEQHYL
HHHHHHCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
QLLSSYRVEGIVVNAVGMREEALSTLQQSMLPMVLIDRKISDFACDVVGLNNHEAATVAT
HHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHEEECCCCCHHHHHH
EHLLQQGFEAILFLSEPIGTVNTRLERLHAFNQTMAQHAGLLAEQAETPLNDVKQLEGVI
HHHHHHHHHEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RDFNARHRGMRKAVISANGALTLQVARAMRRLGIQWGSDIGLLGFDELEWAELAGVGITT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCHHH
LKQPTYQMGHAALEQLVQRIQGLNTPISEQMFPGELIVRGSTTR
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEECCCCCC
>Mature Secondary Structure 
SSVKAIRASGRATISDVAKTAKTGKTSVSRYLNGEQHLLSDDLKQRIEQAIHQLDYRPS
CCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
QMARSLKGGQTRLIGLIIADITNPYSVDVMRGIEAACRQHGFTLLVCNTNNEVNQEQHYL
HHHHHHCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
QLLSSYRVEGIVVNAVGMREEALSTLQQSMLPMVLIDRKISDFACDVVGLNNHEAATVAT
HHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHEEECCCCCHHHHHH
EHLLQQGFEAILFLSEPIGTVNTRLERLHAFNQTMAQHAGLLAEQAETPLNDVKQLEGVI
HHHHHHHHHEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RDFNARHRGMRKAVISANGALTLQVARAMRRLGIQWGSDIGLLGFDELEWAELAGVGITT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCHHH
LKQPTYQMGHAALEQLVQRIQGLNTPISEQMFPGELIVRGSTTR
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]