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The map label for this gene is dgoR [H]

Identifier: 157368290

GI number: 157368290

Start: 42130

End: 42888

Strand: Direct

Name: dgoR [H]

Synonym: Spro_0041

Alternate gene names: 157368290

Gene position: 42130-42888 (Clockwise)

Preceding gene: 157368289

Following gene: 157368291

Centisome position: 0.77

GC content: 55.34

Gene sequence:

>759_bases
ATGGGAGACGCGGGTAAAGTAAATCCGTTATCACAGCATGGCGAACGCCACGGAGAAATCATGAACAAGCAGCAGATCGG
TAAAACCGACCGCATCATTATCGAGATGGGCCAGCAGATCGTCGGCGGTAAGTATATTCCGGGGGCGGCATTACCCGCAG
AAACGGAACTGTGCGAAGAGTTTGAAACTTCGCGCAATATCATCCGCGAAGTCTTGCGTGCGCTGATGTCCAAGCGGTTG
GTGGAGGTGAAGCGCTATCGTGGCGCATTCGTAACGCTACGCAGCCAGTGGAATTATCTGGATACCGACGTCCTGAACTG
GGTGCTGGCGCAGGATTATGATCCACGGCTGATCGCCTCGATGAGTGAGGTTCGTAACCTGGTGGAGCCAACGATTGCTC
GCTGGGCGGCGGAGCGAGCTACCTCTAGCGAACTTGCGGTGATCGAAGCGGCGCTGAACGATATGAAAATCCATCACCAG
GATCGCGAACGTTTTAATGAGGCCGACATCCGCTATCACGAAGCGGTGCTGGCGGCGGTGCACAACCCGGTTTTGCAACA
GCTTAGCGTGGCGATTAGCTCGCTGCAGCGCGCGGTGTTCGAGCGCACTTATATGTCGGATGAGAACAATATGCCGCGTA
CCTTGCGCGAGCATCAGGAATTGTATGATGCGATCCGTCATCAGGATCCGGATGCCGCAGAGCAGGCGGCACTGGCAATG
ATCGCCAGCTCAACCAAACGCCTAAAGGACATAACATGA

Upstream 100 bases:

>100_bases
TGTGATCTTGATTGTAGTACAACAAAACATATAGGTACTACAATAAGGCGGTGGTTGTTTAGGGAAGTTATCAAGATTGT
GCTGCAACCGCAGGACGCCA

Downstream 100 bases:

>100_bases
GTGACAGCTTTATCGCGATTGACTGGGGTTCCACCAACCTGCGCGCCTGGCGTTACGAACAGGGCGTCTGTGTCGATAGC
CTGCAGTCGCAGGCCGGTGT

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MGDAGKVNPLSQHGERHGEIMNKQQIGKTDRIIIEMGQQIVGGKYIPGAALPAETELCEEFETSRNIIREVLRALMSKRL
VEVKRYRGAFVTLRSQWNYLDTDVLNWVLAQDYDPRLIASMSEVRNLVEPTIARWAAERATSSELAVIEAALNDMKIHHQ
DRERFNEADIRYHEAVLAAVHNPVLQQLSVAISSLQRAVFERTYMSDENNMPRTLREHQELYDAIRHQDPDAAEQAALAM
IASSTKRLKDIT

Sequences:

>Translated_252_residues
MGDAGKVNPLSQHGERHGEIMNKQQIGKTDRIIIEMGQQIVGGKYIPGAALPAETELCEEFETSRNIIREVLRALMSKRL
VEVKRYRGAFVTLRSQWNYLDTDVLNWVLAQDYDPRLIASMSEVRNLVEPTIARWAAERATSSELAVIEAALNDMKIHHQ
DRERFNEADIRYHEAVLAAVHNPVLQQLSVAISSLQRAVFERTYMSDENNMPRTLREHQELYDAIRHQDPDAAEQAALAM
IASSTKRLKDIT
>Mature_251_residues
GDAGKVNPLSQHGERHGEIMNKQQIGKTDRIIIEMGQQIVGGKYIPGAALPAETELCEEFETSRNIIREVLRALMSKRLV
EVKRYRGAFVTLRSQWNYLDTDVLNWVLAQDYDPRLIASMSEVRNLVEPTIARWAAERATSSELAVIEAALNDMKIHHQD
RERFNEADIRYHEAVLAAVHNPVLQQLSVAISSLQRAVFERTYMSDENNMPRTLREHQELYDAIRHQDPDAAEQAALAMI
ASSTKRLKDIT

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=227, Percent_Identity=77.9735682819383, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI48994961, Length=214, Percent_Identity=30.8411214953271, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789621, Length=210, Percent_Identity=29.0476190476191, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789353, Length=224, Percent_Identity=27.6785714285714, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790780, Length=193, Percent_Identity=29.5336787564767, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790032, Length=212, Percent_Identity=29.2452830188679, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28690; Mature: 28559

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDAGKVNPLSQHGERHGEIMNKQQIGKTDRIIIEMGQQIVGGKYIPGAALPAETELCEE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
FETSRNIIREVLRALMSKRLVEVKRYRGAFVTLRSQWNYLDTDVLNWVLAQDYDPRLIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHCCCCHHHHHH
MSEVRNLVEPTIARWAAERATSSELAVIEAALNDMKIHHQDRERFNEADIRYHEAVLAAV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HNPVLQQLSVAISSLQRAVFERTYMSDENNMPRTLREHQELYDAIRHQDPDAAEQAALAM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IASSTKRLKDIT
HHHHHHHHHCCC
>Mature Secondary Structure 
GDAGKVNPLSQHGERHGEIMNKQQIGKTDRIIIEMGQQIVGGKYIPGAALPAETELCEE
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
FETSRNIIREVLRALMSKRLVEVKRYRGAFVTLRSQWNYLDTDVLNWVLAQDYDPRLIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHCCCCHHHHHH
MSEVRNLVEPTIARWAAERATSSELAVIEAALNDMKIHHQDRERFNEADIRYHEAVLAAV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HNPVLQQLSVAISSLQRAVFERTYMSDENNMPRTLREHQELYDAIRHQDPDAAEQAALAM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IASSTKRLKDIT
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]