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The map label for this gene is xylA

Identifier: 157157106

GI number: 157157106

Start: 4042152

End: 4043474

Strand: Reverse

Name: xylA

Synonym: EcE24377A_4061

Alternate gene names: 157157106

Gene position: 4043474-4042152 (Counterclockwise)

Preceding gene: 157155273

Following gene: 157155057

Centisome position: 81.2

GC content: 50.64

Gene sequence:

>1323_bases
ATGCAAGCCTATTTTGACCAGCTCGATCGCGTTCGTTATGAAGGCTCAAAATCCTCAAACCCGTTAGCATTCCGTCACTA
CAATCCCGACGAACTGGTGTTGGGTAAGCGTATGGAAGAGCACTTGCGTTTTGCCGCCTGCTACTGGCACACCTTCTGCT
GGAACGGGGCGGACATGTTTGGTGTGGGGGCGTTTAATCGTCCGTGGCAGCAGCCTGGTGAGGCACTGGCGTTGGCGAAG
CGTAAAGCAGATGTCGCATTTGAGTTTTTCCACAAGTTACATGTGCCATTTTATTGCTTCCACGATGTGGATGTTTCCCC
TGAGGGCGCGTCGTTAAAAGAGTACATCAATAATTTTGCGCAAATGGTTGATGTCCTGGCAGCCAAGCAAGAAGAGAGCG
GCGTGAAGCTGCTGTGGGGAACCGCTAACTGCTTTACAAACCCTCGCTATGGCGCGGGTGCGGCGACGAACCCAGATCCT
GAAGTCTTCAGCTGGGCGGCAACGCAAGTTGTTACAGCGATGGAAGCAACCCATAAATTGGGCGGTGAAAACTATGTCCT
GTGGGGTGGTCGTGAAGGTTACGAAACGCTGTTAAATACCGACTTGCGTCAGGAGCGTGAACAACTGGGCCGCTTTATGC
AGATGGTGGTTGAGCATAAACATAAAATCGGCTTCCAGGGCACGTTGCTTATCGAACCGAAACCGCAAGAACCGACTAAA
CATCAATATGATTACGATGCCGCGACGGTCTATGGCTTCCTGAAACAGTTTGGTCTGGAAAAAGAGATTAAACTGAACAT
TGAAGCTAACCACGCGACGCTGGCAGGTCACTCTTTCCATCATGAAATAGCCACCGCCATTGCGCTTGGCCTGTTCGGTT
CTGTCGACGCCAACCGTGGCGATGCGCAACTGGGCTGGGACACCGACCAGTTCCCGAACAGTGTGGAAGAGAATGCGCTG
GTGATGTATGAAATTCTCAAAGCAGGCGGTTTCACCACCGGTGGTCTGAACTTCGATGCCAAAGTACGTCGTCAAAGTAC
TGATAAATATGATCTGTTTTACGGTCATATCGGCGCGATGGATACGATGGCACTGGCGCTGAAAATTGCAGCGCGCATGA
TTGAAGATGGCGAGCTGGATAAACGCATCGCGCAGCGTTATTCCGGCTGGAATAGCGAATTGGGCCAGCAAATCCTGAAA
GGCCAAATGTCACTGGCAGATTTAGCCAAATATGCTCAGGAACATAATTTGTCTCCGGTGCATCAGAGTGGTCGCCAGGA
GCAACTGGAAAATCTGGTAAATCATTATCTGTTCGACAAATAA

Upstream 100 bases:

>100_bases
AATAGCAGTGTGAAATAACATAATTGAGCAACTGAAAGGGAGTGCCCAATATTACGACATCATCCATCACCCGCGGCATT
ACCTGATTATGGAGTTCAAT

Downstream 100 bases:

>100_bases
CGGCTAACTGTGCAGTCCGTTGGCCCGGTTATCGGTAGCGATACCGGGCATTTTTTTAAGGAACGATCGATATGTATATC
GGGATAGATCTTGGCACCTC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAK
RKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAAKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTK
HQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENAL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILK
GQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK

Sequences:

>Translated_440_residues
MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAK
RKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAAKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTK
HQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENAL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILK
GQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
>Mature_440_residues
MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAK
RKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAAKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTK
HQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENAL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILK
GQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=440, Percent_Identity=99.5454545454545, Blast_Score=918, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_ECO24 (A7ZTB2)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001465041.1
- ProteinModelPortal:   A7ZTB2
- SMR:   A7ZTB2
- STRING:   A7ZTB2
- EnsemblBacteria:   EBESCT00000019554
- GeneID:   5586302
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_4061
- eggNOG:   COG2115
- GeneTree:   EBGT00050000011705
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- BioCyc:   ECOL331111:ECE24377A_4061-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49734; Mature: 49734

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 101-101 ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMF
CCHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
GVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFA
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHH
QMVDVLAAKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKL
HHHHHHHHHCCCCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTK
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
HQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAM
CCCCCCCCHHCCCCHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHH
DTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHH
HQSGRQEQLENLVNHYLFDK
HHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMF
CCHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
GVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFA
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHH
QMVDVLAAKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKL
HHHHHHHHHCCCCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTK
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
HQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAM
CCCCCCCCHHCCCCHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHH
DTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHH
HQSGRQEQLENLVNHYLFDK
HHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA