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The map label for this gene is xylB [H]

Identifier: 157155057

GI number: 157155057

Start: 4040626

End: 4042080

Strand: Reverse

Name: xylB [H]

Synonym: EcE24377A_4060

Alternate gene names: 157155057

Gene position: 4042080-4040626 (Counterclockwise)

Preceding gene: 157157106

Following gene: 157156182

Centisome position: 81.17

GC content: 54.16

Gene sequence:

>1455_bases
ATGTATATCGGGATAGATCTTGGCACCTCGGGCGTAAAAGTTATTTTGCTCAACGAGCAGGGTGAGGTGGTTGCTTCGCA
AACGGAAAAGCTGACCGTTTCGCGCCCGCATCCACTCTGGTCGGAACAAGACCCGGAACAGTGGTGGCAGGCAACTGATC
GCGCAATGAAAGCTCTGGGCGATCAGCATTCTCTGCAGGACGTTAAAGCATTGGGTATTGCCGGCCAGATGCATGGAGCA
ACCTTACTGGATGCTCAACAACGGGTATTGCGCCCTGCCATTTTGTGGAACGACGGGCGCTGTGCGCAAGAGTGCACTTT
GCTGGAAGCGAGAGTTCCGCAATCACGAGTGATTACCGGCAACCTGATGATGCCCGGATTTACTGCGCCTAAATTGCTAT
GGGTTCAGCGGCATGAGCCGGAGATATTCCGTCAAATCGACAAAGTATTATTACCGAAAGATTACTTGCGTCTGCGTATG
ACGGGGGAGTTTGCCAGCGATATGTCTGACGCAGCTGGCACCATGTGGCTGGATGTCGCAAAGCGTGACTGGAGTGACGT
CATGCTGCAGGCTTGCGACTTATCTCGTGACCAGATGCCCGCATTATACGAAGGCAGCGAAATTACTGGTGCTTTGTTAC
CTGAAGTTGCGAAAGCGTGGGGTATGGCGACGGTGCCAGTTGTCGCAGGCGGTGGCGACAATGCAGCTGGTGCAGTTGGT
GTGGGAATGGTTGATGCTAATCAGGCAATGTTATCGCTGGGGACGTCGGGGGTCTATTTTGCTGTCAGCGAAGGGTTCTT
AAGCAAGTCAGAAAGCGCTGTACACAGCTTTTGCCATGCGCTACCGCAGCGTTGGCATTTAATGTCTGTAATGCTGAGTG
CAGCATCGTGTCTGGATTGGGTCGCGAAATTAACCGGCCTGTGCAATGTCCCAGCTTTAATCGCCGCAGCTCAACAGGCT
GATGAAAGTGCCGAGCCAGTTTGGTTTCTGCCTTATCTTTCCGGCGAGCGTACACCACACAATAATCCCCAGGCGAAGGG
GGTTTTCTTTGGTTTGACTCATCAACATGGCCCCAATGAACTGGCGCGAGCAGTGCTGGAAGGCGTGGGTTATGCGCTGG
CAGATGGCATGGATGTCGTGCATGCCTGCGGCATTAAACCGCAAAGTGTTACGTTGATTGGTGGCGGGGCGCGTAGTGAG
TACTGGCGTCAGATGCTGGCGGATATCAGCGGTCAGCAGCTCGATTACCGTACGGGGGGGGATGTGGGGCCAGCACTGGG
CGCAGCAAGGCTGGCGCAGATTGCGGCGAATCCAGAGAAATCGCTCATTGAGTTGTTGCCGCAGCTACCGTTAGAACAGT
CGCATCTACCAGATGCGCAGCGTTATGCCGCTTATCAGCCACGACGTGAAACGTTCCGTCGCCTCTATCAGCAACTTCTG
CCATTAATGGCGTAA

Upstream 100 bases:

>100_bases
TGGTAAATCATTATCTGTTCGACAAATAACGGCTAACTGTGCAGTCCGTTGGCCCGGTTATCGGTAGCGATACCGGGCAT
TTTTTTAAGGAACGATCGAT

Downstream 100 bases:

>100_bases
ACGTTATCCCCTGCCTGACCGGGTGGGGGATAATTCACATCTATATATCTCACTAATTAATTAATATTTAGTATGAATTT
ATTCTGAAAATCATTTGTTA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKSESAVHSFCHALPQRWHLMSVMLSAASCLDWVAKLTGLCNVPALIAAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA

Sequences:

>Translated_484_residues
MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKSESAVHSFCHALPQRWHLMSVMLSAASCLDWVAKLTGLCNVPALIAAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA
>Mature_484_residues
MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKSESAVHSFCHALPQRWHLMSVMLSAASCLDWVAKLTGLCNVPALIAAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=437, Percent_Identity=22.4256292906178, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI189409120, Length=436, Percent_Identity=22.4770642201835, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4504007, Length=436, Percent_Identity=22.4770642201835, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI41393575, Length=437, Percent_Identity=23.1121281464531, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI164663828, Length=534, Percent_Identity=23.2209737827715, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI164663830, Length=557, Percent_Identity=22.0825852782765, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=99.1735537190083, Blast_Score=983, Evalue=0.0,
Organism=Escherichia coli, GI1790361, Length=487, Percent_Identity=24.6406570841889, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790005, Length=492, Percent_Identity=23.9837398373984, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787789, Length=510, Percent_Identity=26.078431372549, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789168, Length=421, Percent_Identity=26.3657957244656, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17535599, Length=437, Percent_Identity=23.7986270022883, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17864214, Length=462, Percent_Identity=22.2943722943723, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24655555, Length=458, Percent_Identity=23.7991266375546, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655560, Length=458, Percent_Identity=23.7991266375546, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655570, Length=458, Percent_Identity=23.7991266375546, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655574, Length=458, Percent_Identity=23.7991266375546, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655565, Length=458, Percent_Identity=23.7991266375546, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24654573, Length=392, Percent_Identity=22.7040816326531, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24657106, Length=470, Percent_Identity=22.9787234042553, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24657102, Length=470, Percent_Identity=22.9787234042553, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920476, Length=490, Percent_Identity=23.6734693877551, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356607, Length=319, Percent_Identity=23.8244514106583, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922058, Length=459, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52669; Mature: 52669

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
CEEEEEECCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
DQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHCCCCCEEEEC
NLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
CEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHCCCEEEHHH
KRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
HCCHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
VGMVDANQAMLSLGTSGVYFAVSEGFLSKSESAVHSFCHALPQRWHLMSVMLSAASCLDW
EEEECCCHHHHHCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKLTGLCNVPALIAAAQQADESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNE
HHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECCCCC
DVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
PLMA
HHCC
>Mature Secondary Structure
MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
CEEEEEECCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
DQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHCCCCCEEEEC
NLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
CEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHCCCEEEHHH
KRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
HCCHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
VGMVDANQAMLSLGTSGVYFAVSEGFLSKSESAVHSFCHALPQRWHLMSVMLSAASCLDW
EEEECCCHHHHHCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKLTGLCNVPALIAAAQQADESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNE
HHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECCCCC
DVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
PLMA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]