BacMap

Definition	Escherichia coli HS, complete genome.
Accession	NC_009800
Length	4,643,538

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The map label for this gene is phnK [H]

Identifier: 157163563

GI number: 157163563

Start: 4342576

End: 4343334

Strand: Reverse

Name: phnK [H]

Synonym: EcHS_A4338

Alternate gene names: 157163563

Gene position: 4343334-4342576 (Counterclockwise)

Preceding gene: 157163564

Following gene: 157163562

Centisome position: 93.54

GC content: 61.0

Gene sequence:

>759_bases
ATGAATAAACCGTTACTTTCAGTCAATAACCTGACCCACCTTTACGCGCCGGGCAAAGGCTTTAGCGATGTCTCTTTTGA
TTTATGGCCGGGAGAAGTGCTGGGCATTGTCGGAGAATCCGGCTCCGGGAAGACCACGCTGCTGAAGTCGATCTCCGCGC
GTCTGACGCCGCAGCAGGGGGAGATTCACTACGAGAACCGTTCGCTGTATGCAATGAGCGAGGCCGACCGCCGTCGCCTG
CTGCGCACCGAATGGGGCGTAGTGCATCAGCATCCACTCGACGGCCTGCGCCGTCAGGTCTCGGCAGGCGGCAATATCGG
CGAGCGGTTGATGGCGACCGGGGCGCGTCATTACGGCGACATTCGCGCCACCGCGCAGAAGTGGCTGGAAGAGGTGGAGA
TTCCCGCCAACCGGATCGACGACCTGCCGACCACCTTTTCCGGCGGTATGCAGCAGCGTTTGCAGATTGCCCGCAACCTG
GTGACGCATCCGAAGCTGGTGTTTATGGATGAACCGACCGGCGGGCTGGATGTGTCGGTGCAGGCCCGCCTGCTCGACCT
GCTGCGCGGCCTGGTGGTGGAGCTGAACCTCGCGGTGGTGATTGTCACCCATGATTTAGGCGTCGCCCGCCTGCTGGCGG
ACCGTTTGCTGGTGATGAAGCAGGGGCAAGTGGTGGAGAGTGGGTTAACCGACCGCGTGCTCGACGACCCGCATCATCCG
TATACACAGCTGCTGGTGTCATCGGTTTTGCAGAATTGA

Upstream 100 bases:

>100_bases
ACAGCTATCTTGATGAAGTGGTGCTGGATGACGCCGGAAACCGCATGTTTGTCTGCTCCGATACCGATTATTGCCGCCAA
CAGAGCGAGGCGAAAAGCCA

Downstream 100 bases:

>100_bases
GCCGGTGCCGGATGCGGCGTAAACGCCTTATCCGGCCTACAAATGCGCTCCCCGTAGGTCGGATAAGACGCGTCAGCGTC
GCATCCGACACCCGAACCAC

Product: phosphonate C-P lyase system protein PhnK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNKPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRL
LRTEWGVVHQHPLDGLRRQVSAGGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLVMKQGQVVESGLTDRVLDDPHHP
YTQLLVSSVLQN

Sequences:

>Translated_252_residues
MNKPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRL
LRTEWGVVHQHPLDGLRRQVSAGGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLVMKQGQVVESGLTDRVLDDPHHP
YTQLLVSSVLQN
>Mature_252_residues
MNKPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRL
LRTEWGVVHQHPLDGLRRQVSAGGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLVMKQGQVVESGLTDRVLDDPHHP
YTQLLVSSVLQN

Specific function: Part of the binding-protein-dependent transport system for alkylphosphonates. Probably responsible for energy coupling to the transport system [H]

COG id: COG4107

COG function: function code P; ABC-type phosphonate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=240, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI171184400, Length=240, Percent_Identity=28.75, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI47078218, Length=226, Percent_Identity=25.6637168141593, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI45446740, Length=226, Percent_Identity=25.6637168141593, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI21536376, Length=225, Percent_Identity=24, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI27436953, Length=203, Percent_Identity=25.1231527093596, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI105990541, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI156105685, Length=247, Percent_Identity=27.5303643724696, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27262624, Length=206, Percent_Identity=25.7281553398058, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27262626, Length=206, Percent_Identity=25.7281553398058, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI21536378, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI116734710, Length=215, Percent_Identity=26.5116279069767, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI48994997, Length=252, Percent_Identity=99.6031746031746, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1787500, Length=232, Percent_Identity=36.6379310344828, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1789962, Length=259, Percent_Identity=34.7490347490347, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1789963, Length=257, Percent_Identity=35.408560311284, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI145693107, Length=266, Percent_Identity=34.2105263157895, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788506, Length=264, Percent_Identity=36.3636363636364, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI48994883, Length=254, Percent_Identity=33.8582677165354, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787758, Length=219, Percent_Identity=38.8127853881278, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787759, Length=260, Percent_Identity=34.6153846153846, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788225, Length=251, Percent_Identity=34.2629482071713, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788761, Length=235, Percent_Identity=32.7659574468085, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87081834, Length=233, Percent_Identity=35.6223175965665, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787792, Length=232, Percent_Identity=33.1896551724138, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787548, Length=263, Percent_Identity=29.277566539924, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786398, Length=250, Percent_Identity=26, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789672, Length=248, Percent_Identity=30.241935483871, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=30.0429184549356, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786872, Length=246, Percent_Identity=31.3008130081301, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787089, Length=225, Percent_Identity=31.5555555555556, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787029, Length=236, Percent_Identity=30.5084745762712, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787547, Length=261, Percent_Identity=29.1187739463602, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789032, Length=230, Percent_Identity=28.695652173913, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87081791, Length=260, Percent_Identity=26.9230769230769, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789890, Length=229, Percent_Identity=31.4410480349345, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789864, Length=248, Percent_Identity=27.0161290322581, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786703, Length=196, Percent_Identity=35.2040816326531, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788644, Length=260, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790525, Length=256, Percent_Identity=26.953125, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87081709, Length=227, Percent_Identity=25.5506607929515, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790162, Length=248, Percent_Identity=28.2258064516129, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1787370, Length=254, Percent_Identity=25.1968503937008, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789991, Length=227, Percent_Identity=28.6343612334802, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787712, Length=249, Percent_Identity=28.1124497991968, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788450, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790739, Length=237, Percent_Identity=32.0675105485232, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790190, Length=232, Percent_Identity=26.7241379310345, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789873, Length=224, Percent_Identity=29.0178571428571, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787164, Length=221, Percent_Identity=30.316742081448, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790467, Length=240, Percent_Identity=27.5, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082268, Length=236, Percent_Identity=27.9661016949153, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790534, Length=190, Percent_Identity=33.1578947368421, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787112, Length=211, Percent_Identity=29.8578199052133, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=30.0925925925926, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787105, Length=237, Percent_Identity=28.6919831223629, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788897, Length=229, Percent_Identity=26.6375545851528, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786803, Length=214, Percent_Identity=28.9719626168224, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48995001, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786345, Length=218, Percent_Identity=28.8990825688073, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786253, Length=205, Percent_Identity=27.3170731707317, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789586, Length=226, Percent_Identity=27.4336283185841, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789593, Length=238, Percent_Identity=26.890756302521, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786319, Length=231, Percent_Identity=24.6753246753247, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI87082267, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788053, Length=206, Percent_Identity=29.6116504854369, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=234, Percent_Identity=26.4957264957265, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789751, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081782, Length=238, Percent_Identity=26.890756302521, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786653, Length=234, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787182, Length=210, Percent_Identity=24.7619047619048, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786981, Length=206, Percent_Identity=30.5825242718447, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=233, Percent_Identity=27.4678111587983, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193208177, Length=233, Percent_Identity=27.4678111587983, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17558664, Length=259, Percent_Identity=28.957528957529, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71984940, Length=215, Percent_Identity=29.3023255813954, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193209708, Length=226, Percent_Identity=27.8761061946903, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25146777, Length=241, Percent_Identity=29.8755186721992, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI212646699, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193211015, Length=221, Percent_Identity=28.5067873303167, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71996809, Length=221, Percent_Identity=28.5067873303167, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193211017, Length=221, Percent_Identity=28.5067873303167, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=224, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71992290, Length=235, Percent_Identity=25.9574468085106, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115534520, Length=248, Percent_Identity=26.2096774193548, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567265, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=235, Percent_Identity=24.6808510638298, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=246, Percent_Identity=30.0813008130081, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324985, Length=238, Percent_Identity=27.3109243697479, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323959, Length=255, Percent_Identity=30.1960784313725, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24641565, Length=220, Percent_Identity=29.5454545454545, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI85726357, Length=229, Percent_Identity=28.82096069869, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397593, Length=253, Percent_Identity=27.6679841897233, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653245, Length=226, Percent_Identity=28.7610619469027, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363262, Length=226, Percent_Identity=28.7610619469027, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666092, Length=219, Percent_Identity=24.6575342465753, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357907, Length=227, Percent_Identity=28.6343612334802, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136662, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076682, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076684, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581617, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581615, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24659289, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643674, Length=201, Percent_Identity=25.8706467661692, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573571, Length=241, Percent_Identity=21.9917012448133, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17136592, Length=234, Percent_Identity=26.4957264957265, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI28573573, Length=236, Percent_Identity=22.4576271186441, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR012700
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 27831; Mature: 27831

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTPQQG
CCCCCEEECCCEEEECCCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCC
EIHYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSAGGNIGERLMATGARHYGD
CEEECCCEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNLVTHPKLVFMDEPTGGLDVSV
HHHHHHHHHHHHCCCHHHHCCCCCHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHH
QARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLVMKQGQVVESGLTDRVLDDPHHP
HHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHCCCCHHHCCCCCCH
YTQLLVSSVLQN
HHHHHHHHHHCC
>Mature Secondary Structure
MNKPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTPQQG
CCCCCEEECCCEEEECCCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCC
EIHYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSAGGNIGERLMATGARHYGD
CEEECCCEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNLVTHPKLVFMDEPTGGLDVSV
HHHHHHHHHHHHCCCHHHHCCCCCHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHH
QARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLVMKQGQVVESGLTDRVLDDPHHP
HHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHCCCCHHHCCCCCCH
YTQLLVSSVLQN
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]