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The map label for this gene is ftsN

Identifier: 157163408

GI number: 157163408

Start: 4150389

End: 4151348

Strand: Reverse

Name: ftsN

Synonym: EcHS_A4165

Alternate gene names: 157163408

Gene position: 4151348-4150389 (Counterclockwise)

Preceding gene: 157163409

Following gene: 157163407

Centisome position: 89.4

GC content: 57.4

Gene sequence:

>960_bases
GTGGCACAACGAGATTATGTACGCCGCAGCCAACCGGCACCTTCGCGGCGAAAAAAGAGCACCTCACGGAAAAAGCAACG
AAATCTGCCTGCGGTTTCTCCCGCTATGGTCGCTATTGCTGCCGCCGTTCTTGTGACCTTTATCGGTGGTCTGTACTTCA
TTACGCATCACAAGAAAGAAGAGTCCGAGACGCTGCAAAGCCAGAAAGTGACCGGAAACGGACTACCACCAAAACCAGAA
GAACGCTGGCGCTACATTAAAGAGCTGGAAAGTCGCCAGCCGGGAGTGCGTGCGCCCACAGAACCTTCTGCCGGTGGTGA
AGTGAAAACGCCGGAGCAACTGACACCAGAACAACGTCAGCTTCTTGAACAAATGCAGGCTGATATGCGCCAGCAGCCAA
CGCAGCTGGTTGAAGTTCCGTGGAATGAACAGACGCCGGAACAGCGTCAGCAAACGCTACAGCGCCAACGTCAGGCGCAG
CAATTAGCGGAACAGCAACGCCTGGCTCAGCAGTCGCGTACGACTGAACAAAGCTGGCAGCAGCAGACGCGTACGTCGCA
AGCCGCACCGGTACAGGCGCAACCGCGCCAGTCTAAACCGGCTTCTTCTCAGCAGCCGTACCAGGATCTGCTGCAAACTC
CTGCGCACACGACTGCGCAGTCGAAGCCGCAGCAAGCTGCGCCAGTTGCTCGTGCCGCTGACGCGCCAAAACCGACGGCG
GAGAAAAAAGACGAACGCCGCTGGATGGTGCAGTGCGGTTCGTTCAGAGGCGCGGAACAGGCAGAGACGGTACGTGCTCA
GCTGGCGTTCGAAGGCTTTGACTCGAAAATCACCACCAACAATGGCTGGAATCGTGTGGTCATTGGCCCGGTGAAAGGCA
AAGAGAACGCAGACAGCACCCTCAATCGGTTGAAGATGGCGGGTCATACAAACTGCATTCGGCTCGCCGCCGGGGGTTGA

Upstream 100 bases:

>100_bases
TTACCTTAAAGTAAACCTTTAAGACTGCCGTGACTGGTCAAAGGCCCGCCGCTTAAGTAACATGGCGGGCTGACGAACGA
ATAAATACAGCGAAACGATA

Downstream 100 bases:

>100_bases
AACCCTCAAAATCCCCCCCATCTATAATTGCATTATGCCCCGTACTTTTGTACGGGGTTTGTACTCTGTATTCGTAACCA
AGGGGTCAGCTCGTGACAAC

Product: essential cell division protein FtsN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPE
ERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTA
EKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG

Sequences:

>Translated_319_residues
MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPE
ERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTA
EKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG
>Mature_318_residues
AQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEE
RWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQ
LAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTAE
KKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG

Specific function: Essential cell division protein. May play a role in the assembly or stability of the septation machinery. May interact with ftsA, PBP3 and ftsQ

COG id: COG3087

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790368, Length=319, Percent_Identity=100, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSN_ECOLI (P29131)

Other databases:

- EMBL:   L14281
- EMBL:   L06547
- EMBL:   L19201
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S40876
- RefSeq:   AP_003876.1
- RefSeq:   NP_418368.1
- PDB:   1UTA
- PDBsum:   1UTA
- ProteinModelPortal:   P29131
- SMR:   P29131
- DIP:   DIP-9705N
- IntAct:   P29131
- STRING:   P29131
- PRIDE:   P29131
- EnsemblBacteria:   EBESCT00000004021
- EnsemblBacteria:   EBESCT00000016728
- GeneID:   948428
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3904
- KEGG:   eco:b3933
- EchoBASE:   EB1491
- EcoGene:   EG11529
- eggNOG:   COG3087
- GeneTree:   EBGT00050000009821
- HOGENOM:   HBG564261
- OMA:   EVPYNDQ
- ProtClustDB:   PRK10927
- BioCyc:   EcoCyc:EG11529-MONOMER
- Genevestigator:   P29131
- InterPro:   IPR011930
- InterPro:   IPR007730
- Gene3D:   G3DSA:3.30.70.1070
- TIGRFAMs:   TIGR02223

Pfam domain/function: PF05036 SPOR; SSF110997 Spore_cell-division_bac

EC number: NA

Molecular weight: Translated: 35794; Mature: 35662

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x188bda6c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKE
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQ
HHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTA
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCHHHCCHHHHCCCCCCCC
EKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADST
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCEEEEECCCCCCCHHHH
LNRLKMAGHTNCIRLAAGG
HHHHHHCCCCCEEEEECCH
>Mature Secondary Structure 
AQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKE
CCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQ
HHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTA
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCHHHCCHHHHCCCCCCCC
EKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADST
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCEEEEECCCCCCCHHHH
LNRLKMAGHTNCIRLAAGG
HHHHHHCCCCCEEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8509333; 8346018; 9278503