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The map label for this gene is dgoA

Identifier: 157163172

GI number: 157163172

Start: 3900166

End: 3900783

Strand: Reverse

Name: dgoA

Synonym: EcHS_A3905

Alternate gene names: 157163172

Gene position: 3900783-3900166 (Counterclockwise)

Preceding gene: 157163173

Following gene: 157163171

Centisome position: 84.0

GC content: 59.39

Gene sequence:

>618_bases
ATGCAGTGGCAAACTAAACTCCCGCTGATCGCCATTTTGCGCGGTATTACGCCCGACGAGGCGCTGGCGCATGTTGGCGC
GGTGATTGACGCCGGGTTCGACGCGGTTGAAATCCCGCTGAATTCCCCACAATGGGAGCAAAGCATTCCCGCCATCGTTG
ATGCGTACGGCGACAAGGCGTTGATTGGCGCAGGTACGGTACTGAAACCTGAACAGGTCGATGCGCTCGCCAGGATGGGC
TGTCAGCTCATCGTTACGCCCAATATCCATAGTGAAGTGATCCGCCGTGCGGTGGGCTACGGCATGACCGTCTGCCCCGG
CTGCGCGACGGCGACCGAAGCCTTTACCGCGCTCGAAGCGGGCGCGCAGGCGCTGAAAATATTTCCGTCATCGGCTTTTG
GTCCGCAATACATCAAAGCGTTAAAAGCGGTATTGCCATCGGACATCGCAGTCTTTGCCGTTGGCGGCGTGACGCCAGAA
AACCTGGCGCAGTGGATAGACGCAGGTTGTGCAGGGGCGGGCTTAGGCAGCGATCTCTATCGCGCCGGGCAATCCGTAGA
GCGCACCGCGCAGCAGGCAGCAGCATTTGTTAAGGCGTATCGAGAGGCAGTGCAATGA

Upstream 100 bases:

>100_bases
CTGACCGCGCGCTACCAGCAAGCCTTTCAGGCGATGGGTTGCGACGTGACGGCGGTGGCGGGCGACACGGCATTTCAGGC
TGGTATAAGGAGCATCGCTC

Downstream 100 bases:

>100_bases
AAATCACCAAAATTACCACGTATCGTTTACCTCCCCGCTGGATGTTCCTGAAAATTGAAACCGATGAAGGCGTGGTCGGT
TGGGGCGAGCCCGTGATCGA

Product: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase

Products: NA

Alternate protein names: 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMG
CQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ

Sequences:

>Translated_205_residues
MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMG
CQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ
>Mature_205_residues
MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMG
CQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ

Specific function: D-galactonate degradation; first step. D-galactonate degradation; third step. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994954, Length=205, Percent_Identity=100, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1788156, Length=150, Percent_Identity=26.6666666666667, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DGOA_ECOLI (Q6BF16)

Other databases:

- EMBL:   L10328
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E65171
- RefSeq:   AP_004100.1
- RefSeq:   YP_026238.1
- PDB:   2V81
- PDB:   2V82
- PDBsum:   2V81
- PDBsum:   2V82
- ProteinModelPortal:   Q6BF16
- SMR:   Q6BF16
- STRING:   Q6BF16
- EnsemblBacteria:   EBESCT00000001871
- EnsemblBacteria:   EBESCT00000016606
- GeneID:   2847766
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5628
- KEGG:   eco:b4477
- EchoBASE:   EB1667
- EcoGene:   EG11716
- eggNOG:   COG0800
- GeneTree:   EBGT00050000010303
- HOGENOM:   HBG670118
- OMA:   SAFGPDY
- ProtClustDB:   PRK09140
- BioCyc:   EcoCyc:DEHYDDEOXPHOSGALACT-ALDOL-MONOMER
- BioCyc:   MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-MONOMER
- Genevestigator:   Q6BF16
- InterPro:   IPR000887
- InterPro:   IPR013785
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF01081 Aldolase

EC number: =4.1.2.21

Molecular weight: Translated: 21391; Mature: 21391

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKA
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCE
LIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEA
EECCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPENLAQWIDAGCAGAGLGSDLY
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHH
RAGQSVERTAQQAAAFVKAYREAVQ
HCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKA
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCE
LIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEA
EECCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPENLAQWIDAGCAGAGLGSDLY
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHH
RAGQSVERTAQQAAAFVKAYREAVQ
HCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503