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The map label for this gene is aaeA [H]

Identifier: 156978227

GI number: 156978227

Start: 2107737

End: 2108786

Strand: Direct

Name: aaeA [H]

Synonym: VIBHAR_07032

Alternate gene names: 156978227

Gene position: 2107737-2108786 (Clockwise)

Preceding gene: 156978218

Following gene: 156978228

Centisome position: 95.63

GC content: 48.57

Gene sequence:

>1050_bases
GTGAAAGAAAATTTTTATAAATACGCGATATACACTGTTTTTTCAGCGGCAGCTTTGTTCTCCACTTTTTTAGTCACCTC
AGACAATGTTTCCCCTTTCACCACCCAAGCGACACTGCATCGTAACGTCGCAACCATTGCGCCGGAGGTATCTGGTGTGA
TTACGGATGTGATGGTGAATAACGGTGAATTGGTTGAAAAAGGTCAGCCACTGTTTGCTATCGATGCCAGCAGCTACCAA
TTGAAAGTGGCACAAGCCAAAGCCGAACTGCGCCAAGCACGTGAATCAGATTCCGCGAAATGGCAACAATTGGCAGCAGC
GAAACAAACCCAAAGCCAACGCGAGTTCGAATACCACAACGCGAAGCAAAAACTGACGCGTAACCAAAAACTGCGCAACA
AAGGGCTGGCAACTGAGCAAGAACTTGATGACGCGATCACCAATACACAAGTCGCCAGCAGCGCGGTTGAAGCAGCGAAC
GCGGAAGTGAAACGCATTGAGGCAGAGCTTTCTACTCAAGACCGCACAGCGGCTATTGAATTGGCAGAAACAAAACTTGC
CAGTGCGGAGCTCGACTTAAGCCATACCCAAATCGTGGCGCAAACTGAAGGCGTGGTAACGAACTTGCAACTGCAATCAG
GCAGCTACATCACACAAGGCACAGCTTCGTTGCTGCTGGTGGACGAAGCTCATGCGTGGATCAGTGCGGACTTCAACGAA
AAAGGCATTGATAAGCTAACTAATGGTCGCGAAGTGTTGGTGTCCTTCGATGCGCTACCAGGCAAAGTATTTACTGGTGA
AGTCAGCAGCCAAGAGCGTGCGATTTACGATACCAACAATGCTAATGGGCAGCTTTCTAGCGTGACCAATGATACTCGCT
GGATCCGTGAGCAACAGAAAGTGCGTACTCGCATTACAGTTAACGAGTTGGATCCTTCTATGATTTCTGGTTCACGAGCA
AGTGTGATCGTTGAAAGCGGCAATCCAATCATGGATGTCATTGGCTCAGCTTGGATTCACTTGGTAGCGATGTTCCGCTA
CATCTACTAG

Upstream 100 bases:

>100_bases
TTTTCCAATTTTAGATAAGTATAACCTAGCCCACGTAGAAAAGAGACCCGAATATGCCGTGAACGCGGCGCGTAATAACG
AATGAATACTAGGTACAGAC

Downstream 100 bases:

>100_bases
GGGGTGAACCATGTGGACCTTCGAAAGCCTGTTTCAAAGTCGTTCTGAGCGCAATGAAGCACTGCGTGTCGCCCTTACTG
TGACAATTTGTATGGTGCTA

Product: hypothetical protein

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKENFYKYAIYTVFSAAALFSTFLVTSDNVSPFTTQATLHRNVATIAPEVSGVITDVMVNNGELVEKGQPLFAIDASSYQ
LKVAQAKAELRQARESDSAKWQQLAAAKQTQSQREFEYHNAKQKLTRNQKLRNKGLATEQELDDAITNTQVASSAVEAAN
AEVKRIEAELSTQDRTAAIELAETKLASAELDLSHTQIVAQTEGVVTNLQLQSGSYITQGTASLLLVDEAHAWISADFNE
KGIDKLTNGREVLVSFDALPGKVFTGEVSSQERAIYDTNNANGQLSSVTNDTRWIREQQKVRTRITVNELDPSMISGSRA
SVIVESGNPIMDVIGSAWIHLVAMFRYIY

Sequences:

>Translated_349_residues
MKENFYKYAIYTVFSAAALFSTFLVTSDNVSPFTTQATLHRNVATIAPEVSGVITDVMVNNGELVEKGQPLFAIDASSYQ
LKVAQAKAELRQARESDSAKWQQLAAAKQTQSQREFEYHNAKQKLTRNQKLRNKGLATEQELDDAITNTQVASSAVEAAN
AEVKRIEAELSTQDRTAAIELAETKLASAELDLSHTQIVAQTEGVVTNLQLQSGSYITQGTASLLLVDEAHAWISADFNE
KGIDKLTNGREVLVSFDALPGKVFTGEVSSQERAIYDTNNANGQLSSVTNDTRWIREQQKVRTRITVNELDPSMISGSRA
SVIVESGNPIMDVIGSAWIHLVAMFRYIY
>Mature_349_residues
MKENFYKYAIYTVFSAAALFSTFLVTSDNVSPFTTQATLHRNVATIAPEVSGVITDVMVNNGELVEKGQPLFAIDASSYQ
LKVAQAKAELRQARESDSAKWQQLAAAKQTQSQREFEYHNAKQKLTRNQKLRNKGLATEQELDDAITNTQVASSAVEAAN
AEVKRIEAELSTQDRTAAIELAETKLASAELDLSHTQIVAQTEGVVTNLQLQSGSYITQGTASLLLVDEAHAWISADFNE
KGIDKLTNGREVLVSFDALPGKVFTGEVSSQERAIYDTNNANGQLSSVTNDTRWIREQQKVRTRITVNELDPSMISGSRA
SVIVESGNPIMDVIGSAWIHLVAMFRYIY

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790024, Length=286, Percent_Identity=26.9230769230769, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789637, Length=319, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081951, Length=298, Percent_Identity=26.1744966442953, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790012, Length=296, Percent_Identity=25.6756756756757, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790519, Length=303, Percent_Identity=25.0825082508251, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789041, Length=288, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38386; Mature: 38386

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENFYKYAIYTVFSAAALFSTFLVTSDNVSPFTTQATLHRNVATIAPEVSGVITDVMVN
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHCCHHHHCCHHHHHEEHEEEC
NGELVEKGQPLFAIDASSYQLKVAQAKAELRQARESDSAKWQQLAAAKQTQSQREFEYHN
CCCEEECCCCEEEEECCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AKQKLTRNQKLRNKGLATEQELDDAITNTQVASSAVEAANAEVKRIEAELSTQDRTAAIE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHEEE
LAETKLASAELDLSHTQIVAQTEGVVTNLQLQSGSYITQGTASLLLVDEAHAWISADFNE
HHHHHHHHHHCCCCHHEEEEECCCEEEEEEECCCCEEECCCEEEEEEECCCEEEECCCCC
KGIDKLTNGREVLVSFDALPGKVFTGEVSSQERAIYDTNNANGQLSSVTNDTRWIREQQK
CCHHHHCCCCEEEEEEECCCCEEEECCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHHH
VRTRITVNELDPSMISGSRASVIVESGNPIMDVIGSAWIHLVAMFRYIY
HHHEEEEECCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKENFYKYAIYTVFSAAALFSTFLVTSDNVSPFTTQATLHRNVATIAPEVSGVITDVMVN
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHCCHHHHCCHHHHHEEHEEEC
NGELVEKGQPLFAIDASSYQLKVAQAKAELRQARESDSAKWQQLAAAKQTQSQREFEYHN
CCCEEECCCCEEEEECCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AKQKLTRNQKLRNKGLATEQELDDAITNTQVASSAVEAANAEVKRIEAELSTQDRTAAIE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHEEE
LAETKLASAELDLSHTQIVAQTEGVVTNLQLQSGSYITQGTASLLLVDEAHAWISADFNE
HHHHHHHHHHCCCCHHEEEEECCCEEEEEEECCCCEEECCCEEEEEEECCCEEEECCCCC
KGIDKLTNGREVLVSFDALPGKVFTGEVSSQERAIYDTNNANGQLSSVTNDTRWIREQQK
CCHHHHCCCCEEEEEEECCCCEEEECCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHHH
VRTRITVNELDPSMISGSRASVIVESGNPIMDVIGSAWIHLVAMFRYIY
HHHEEEEECCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA