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The map label for this gene is lytS [H]

Identifier: 156978220

GI number: 156978220

Start: 2100805

End: 2101827

Strand: Reverse

Name: lytS [H]

Synonym: VIBHAR_07025

Alternate gene names: 156978220

Gene position: 2101827-2100805 (Counterclockwise)

Preceding gene: 156978221

Following gene: 156978219

Centisome position: 95.36

GC content: 48.0

Gene sequence:

>1023_bases
ATGTGTTCAGCAAAATCAGTGGTGAAAAGTGGATGGCCGCGTAGCTTATTAGTGACCACGGCATTTTGTCTCTTTATCGC
AGCAATGACGCTCTCGGTTTGGGGCGGTCCATTTTACATTCATGTAGCGGTTAGCTTTGGATTTGGCTATTCGGCTATCT
TCTTCTCATGGCTTGTCGACCGCCTGTTTCCTACCATTCCTCGTTTGGCGGAAGTGGCTATCTCGCTGACAGCATGCCTA
TTGTTTGGTGTGGTGAACGCCCAGCTTTGGCTTGGGGAATACTTTGGTATTTCAAGTATGCTGTCGGTTGGTCTCATGGG
GTTGTTATTCAGTGCCATGTGCTTTTTCTATTTCTACTCACGCGAGCAACATGCAATCGCTCAACGAGAGTTGGAAGCCA
TCAAACGCGAGAAAGCAGAGCAAGATCGTGCGCTGTTGCTGAGTCAGCTTAAGCAGATGCAAAGCCAGATTGAACCGCAT
TTCTTATTCAATACCTTGGCAAATATCAGTGCGCTCATGTCGCAAGATGTCGATAAAGCCAAGCTAATGCTAGAACAGTT
AACCGCGCTGCTGCGTGCGACGCTCAAAAGCTCACGTGAAGAACGCACCACCATAGACGATGAAACGGCGTTACTTGAGG
CTTACTTAGGCATCCAACAAACTCGTTTGGGTGATCGATTGCGTTACAAGATTGAGGTGGAAGAGGGGTTAGGCAGAACC
GAATTACCGCCGATGATGCTCCAACCTTTAATCGAAAACGCCATCATCCATGGTATTGAGCCAAAGCGTGAAGGTGGCGA
AGTGAGTTTGCAGATTAAGCGCGAACAACAGAACTTGCAGATTGAAGTCAGAGACACTGGTGTTGGCTTGAATCACGTTA
GTGGGCACATGGGCTCCGGCGTGGGTTTAAGTAATCTCAAGCAGCGAGTTGAAGCTTTGTTTTTAGGTAAGGGAGAGGTC
TCCATTAGTGAGTCTGCTCAAGGTGGCGTTTGTATTCGCTTGAGTTGGCCAATTGAATCGTGA

Upstream 100 bases:

>100_bases
GGAAGTTGCCGCACGCTTTTTAACCGGAGACGACCAATCTGCTTACGCACAAATCAATGATAAGCATATGATTGTATTTA
ACATCAAAGGGAAATTCTAA

Downstream 100 bases:

>100_bases
TTAGGGAAAGATATAAATGAATACTGGGTTTACTGCGATTATTGCTGATGATGAACCGTTATTGAGGCGTCATCTAGATA
AAAGCCTAGCTGAAGTGTGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MCSAKSVVKSGWPRSLLVTTAFCLFIAAMTLSVWGGPFYIHVAVSFGFGYSAIFFSWLVDRLFPTIPRLAEVAISLTACL
LFGVVNAQLWLGEYFGISSMLSVGLMGLLFSAMCFFYFYSREQHAIAQRELEAIKREKAEQDRALLLSQLKQMQSQIEPH
FLFNTLANISALMSQDVDKAKLMLEQLTALLRATLKSSREERTTIDDETALLEAYLGIQQTRLGDRLRYKIEVEEGLGRT
ELPPMMLQPLIENAIIHGIEPKREGGEVSLQIKREQQNLQIEVRDTGVGLNHVSGHMGSGVGLSNLKQRVEALFLGKGEV
SISESAQGGVCIRLSWPIES

Sequences:

>Translated_340_residues
MCSAKSVVKSGWPRSLLVTTAFCLFIAAMTLSVWGGPFYIHVAVSFGFGYSAIFFSWLVDRLFPTIPRLAEVAISLTACL
LFGVVNAQLWLGEYFGISSMLSVGLMGLLFSAMCFFYFYSREQHAIAQRELEAIKREKAEQDRALLLSQLKQMQSQIEPH
FLFNTLANISALMSQDVDKAKLMLEQLTALLRATLKSSREERTTIDDETALLEAYLGIQQTRLGDRLRYKIEVEEGLGRT
ELPPMMLQPLIENAIIHGIEPKREGGEVSLQIKREQQNLQIEVRDTGVGLNHVSGHMGSGVGLSNLKQRVEALFLGKGEV
SISESAQGGVCIRLSWPIES
>Mature_340_residues
MCSAKSVVKSGWPRSLLVTTAFCLFIAAMTLSVWGGPFYIHVAVSFGFGYSAIFFSWLVDRLFPTIPRLAEVAISLTACL
LFGVVNAQLWLGEYFGISSMLSVGLMGLLFSAMCFFYFYSREQHAIAQRELEAIKREKAEQDRALLLSQLKQMQSQIEPH
FLFNTLANISALMSQDVDKAKLMLEQLTALLRATLKSSREERTTIDDETALLEAYLGIQQTRLGDRLRYKIEVEEGLGRT
ELPPMMLQPLIENAIIHGIEPKREGGEVSLQIKREQQNLQIEVRDTGVGLNHVSGHMGSGVGLSNLKQRVEALFLGKGEV
SISESAQGGVCIRLSWPIES

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=240, Percent_Identity=30.4166666666667, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788446, Length=204, Percent_Identity=31.3725490196078, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37840; Mature: 37840

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSAKSVVKSGWPRSLLVTTAFCLFIAAMTLSVWGGPFYIHVAVSFGFGYSAIFFSWLVD
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHH
RLFPTIPRLAEVAISLTACLLFGVVNAQLWLGEYFGISSMLSVGLMGLLFSAMCFFYFYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQHAIAQRELEAIKREKAEQDRALLLSQLKQMQSQIEPHFLFNTLANISALMSQDVDKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHH
KLMLEQLTALLRATLKSSREERTTIDDETALLEAYLGIQQTRLGDRLRYKIEVEEGLGRT
HHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCC
ELPPMMLQPLIENAIIHGIEPKREGGEVSLQIKREQQNLQIEVRDTGVGLNHVSGHMGSG
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHCCCCCCC
VGLSNLKQRVEALFLGKGEVSISESAQGGVCIRLSWPIES
CCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MCSAKSVVKSGWPRSLLVTTAFCLFIAAMTLSVWGGPFYIHVAVSFGFGYSAIFFSWLVD
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHH
RLFPTIPRLAEVAISLTACLLFGVVNAQLWLGEYFGISSMLSVGLMGLLFSAMCFFYFYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQHAIAQRELEAIKREKAEQDRALLLSQLKQMQSQIEPHFLFNTLANISALMSQDVDKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHH
KLMLEQLTALLRATLKSSREERTTIDDETALLEAYLGIQQTRLGDRLRYKIEVEEGLGRT
HHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCC
ELPPMMLQPLIENAIIHGIEPKREGGEVSLQIKREQQNLQIEVRDTGVGLNHVSGHMGSG
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHCCCCCCC
VGLSNLKQRVEALFLGKGEVSISESAQGGVCIRLSWPIES
CCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]