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The map label for this gene is nagB [H]

Identifier: 156978197

GI number: 156978197

Start: 2082043

End: 2082843

Strand: Direct

Name: nagB [H]

Synonym: VIBHAR_07002

Alternate gene names: 156978197

Gene position: 2082043-2082843 (Clockwise)

Preceding gene: 156978195

Following gene: 156978200

Centisome position: 94.47

GC content: 47.19

Gene sequence:

>801_bases
ATGAGACTTATCCCGTTAGCTCAAGCAGCACAAGTAGGCAAGTGGGCAGCAGCACACATCGCTAAGCGCATCAACGACTT
CAAACCAACTGCTGAGCGTCCGTTCGTTCTGGGTCTACCTACTGGTGGCACTCCTCTAGCAACTTACAAAGCATTGATCG
AACTTTACCAAGCTGGTGAAGTGAGCTTCGAACACGTTGTGACTTTCAACATGGACGAGTACATCGGTATCCCTGCGGAT
CACCCAGAATCATACCGTTCATTCATGTACACAAACTTCTTCAACCACGTGAACATCCAAGAAGCGAACATCAACCTTCT
TAACGGTAACGCGGAAGATCACGAAGCGGAATGCCAACGCTACGAAGACAAAATCAAGTCTTACGGCAAGATCAACCTAT
TCATGGGCGGCGTAGGTAACGACGGTCACATCGCATTCAACGAGCCAGCATCTTCTCTGTCTTCTCGCACTCGCATCAAG
ACACTAACTGAAGACACTCGTATCGCGAACTCTCGTTTCTTCGATGGCGACATCAACCAAGTTCCTAAGTACGCACTAAC
TATCGGTGTTGGTACGCTACTAGACGCTGAAGAAGTGATGATCCTAGTAACTGGTCACAACAAAGCACTTGCTCTAGAAG
CAGCTGTAGAAGGCAGCGTAAACCACCTATGGACGGTTTCTGCACTTCAACTTCACCCTAAAGCAGTGATCGTTTGTGAT
GAGCCTTCACAACAAGAGCTTAAAGTGAAGACAGTTAAGTACTTCTCTGAGCTAGAAGCGGAAAACATCAAAGGTTTCTA
A

Upstream 100 bases:

>100_bases
CAAATTTTTGACCTAAAACAATAGCAGATTGTCATCACTTATTTTATAATGCAAATTAATGTTTCAGGACATCTTAAATT
CCAATAACTAGGGGCACAAA

Downstream 100 bases:

>100_bases
TCCTTCGGGTAACAACCAAAAATAAACACTGAATACACAAAACCCGTGAGTCATCACGGTTTTTTTCGTTTTTAAAGATT
AGCAGGTTTAAAGGTTTAGG

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRLIPLAQAAQVGKWAAAHIAKRINDFKPTAERPFVLGLPTGGTPLATYKALIELYQAGEVSFEHVVTFNMDEYIGIPAD
HPESYRSFMYTNFFNHVNIQEANINLLNGNAEDHEAECQRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIK
TLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDAEEVMILVTGHNKALALEAAVEGSVNHLWTVSALQLHPKAVIVCD
EPSQQELKVKTVKYFSELEAENIKGF

Sequences:

>Translated_266_residues
MRLIPLAQAAQVGKWAAAHIAKRINDFKPTAERPFVLGLPTGGTPLATYKALIELYQAGEVSFEHVVTFNMDEYIGIPAD
HPESYRSFMYTNFFNHVNIQEANINLLNGNAEDHEAECQRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIK
TLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDAEEVMILVTGHNKALALEAAVEGSVNHLWTVSALQLHPKAVIVCD
EPSQQELKVKTVKYFSELEAENIKGF
>Mature_266_residues
MRLIPLAQAAQVGKWAAAHIAKRINDFKPTAERPFVLGLPTGGTPLATYKALIELYQAGEVSFEHVVTFNMDEYIGIPAD
HPESYRSFMYTNFFNHVNIQEANINLLNGNAEDHEAECQRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIK
TLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDAEEVMILVTGHNKALALEAAVEGSVNHLWTVSALQLHPKAVIVCD
EPSQQELKVKTVKYFSELEAENIKGF

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=60.4651162790698, Blast_Score=336, Evalue=1e-92,
Organism=Homo sapiens, GI19923881, Length=258, Percent_Identity=58.1395348837209, Blast_Score=326, Evalue=1e-89,
Organism=Escherichia coli, GI1786893, Length=266, Percent_Identity=78.1954887218045, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1789530, Length=236, Percent_Identity=27.9661016949153, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI48994958, Length=245, Percent_Identity=26.9387755102041, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554876, Length=258, Percent_Identity=58.5271317829457, Blast_Score=312, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24581960, Length=255, Percent_Identity=59.6078431372549, Blast_Score=338, Evalue=2e-93,
Organism=Drosophila melanogaster, GI19920764, Length=255, Percent_Identity=59.6078431372549, Blast_Score=338, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 29484; Mature: 29484

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIPLAQAAQVGKWAAAHIAKRINDFKPTAERPFVLGLPTGGTPLATYKALIELYQAGE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
VSFEHVVTFNMDEYIGIPADHPESYRSFMYTNFFNHVNIQEANINLLNGNAEDHEAECQR
CCEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECEEEEEECCCCCHHHHHHH
YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQ
HHHHHHCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHH
VPKYALTIGVGTLLDAEEVMILVTGHNKALALEAAVEGSVNHLWTVSALQLHPKAVIVCD
CCCEEEEEECCCEECCCEEEEEEECCCCEEEEEEECCCCCCEEEEEEEEEECCCEEEEEC
EPSQQELKVKTVKYFSELEAENIKGF
CCCCHHHHHHHHHHHHHHCHHHCCCC
>Mature Secondary Structure
MRLIPLAQAAQVGKWAAAHIAKRINDFKPTAERPFVLGLPTGGTPLATYKALIELYQAGE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
VSFEHVVTFNMDEYIGIPADHPESYRSFMYTNFFNHVNIQEANINLLNGNAEDHEAECQR
CCEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECEEEEEECCCCCHHHHHHH
YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQ
HHHHHHCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHH
VPKYALTIGVGTLLDAEEVMILVTGHNKALALEAAVEGSVNHLWTVSALQLHPKAVIVCD
CCCEEEEEECCCEECCCEEEEEEECCCCEEEEEEECCCCCCEEEEEEEEEECCCEEEEEC
EPSQQELKVKTVKYFSELEAENIKGF
CCCCHHHHHHHHHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA