Click here to switch to the map view.

The map label for this gene is bglB [H]

Identifier: 156978133

GI number: 156978133

Start: 2033548

End: 2034897

Strand: Reverse

Name: bglB [H]

Synonym: VIBHAR_06938

Alternate gene names: 156978133

Gene position: 2034897-2033548 (Counterclockwise)

Preceding gene: 156978134

Following gene: 156978132

Centisome position: 92.33

GC content: 48.74

Gene sequence:

>1350_bases
ATGAATAAATTCCAACTACCACAAGATTCAAAATTACGTAGCCCAGAGTTCTTATTTGGTGTCGCAACCTCTTCTTATCA
GATTGAGGGTGGTGCTCAGCTAGGTGGTCGTACGCCTTCGATTTGGGACACGTTTTGCAATAAGCCAGGCGCAGTTGATA
ACGCAGATAATGGCGACGTGGCATGTGATCACTTCCATTTGTGGAAGCAAGACATTGAGATGATTCAAGGTTTGGGTGTG
GGCGCTTACCGTCTATCGATGGCGTGGCCGCGCATCATCCCTGAAGATGGCAAAGTGAATGAAGAAGGTTTGAAGTTTTA
CGAGCAAATCATCGATGAGTGTCACGCTCGCGGTTTGAAGGTTTTCGTTACGCTTTACCATTGGGATCTACCGCAATACC
TAGAAGACAAAGGCGGTTGGCTAAACCGAGAAACGGCTTACAAGTTTGAGGAATACGCGAAGGTAGTTAGTGCTTACTTC
GGTGATAAGATTGATTCATACGCGACATTGAACGAACCGTTCTGCTCTGCTTATCTGGGCTACCGTTGGGGTGAACATGC
TCCTGGCCTTAAAGGCGAGCGTGAAGGTTTCTTGTCTGCGCACCACTTGATGCTGGCACATGGTTTGGCGATTCCACACA
TGCGCAAGAACGCACCAAATGCGATGCACGGTTGTGTGTTCAATGCGACACCTGCTTACCCATATGGCGAGGCAGATATC
GGTGCGGCAGAGTACAGCGATGCGGAAGGTTACCACTGGTTTATGGACCCGGTATTAAAAGGCGAATATCCGCAGCTTGT
GGTAAAGCGCCAATCGCACAACATGCCAATGATTCTAGAGGGCGATCTCGACATCATCCAGACCGATTTGGACTTTATCG
GCATTAACTTCTACACCCGTTGTGTTGTGCGCTACAACGAACATGGCGATATTGAAACGGTACCTCAACCAGAACAAGAG
CACACATTCATTGGTTGGGAAATTCACCCGCAAGCACTGACAGATTTGCTTCTGCGTTTGAACGACCGTTACCCGAACTT
GCCACCACTTTACATCACAGAAAACGGCGCAGCAGGCGATGATCATTGCATTGAAGGCGAAGTGAATGATGAGCAGCGCG
TGCGTTACTTCCAGCAGCATCTAGTAGCGTTGGATGCCGCGATTAAAGCGGGTGTGGATGTGGATGGTTACTTCGCTTGG
AGCCTCATGGATAACTTTGAGTGGGCTTACGGTTATAAGCAGCGCTTTGGCATTGTTCACGTGGATTACCAAACGCAAAA
GCGCACCTTAAAAGCGAGCGCAATTGCTTACCGTAATATGCTGCTAGACCGAGCAGAGGAGAACCAGTAA

Upstream 100 bases:

>100_bases
TACCGTTAGTGATTACTTACTTATTTGCCTCAAAACAGATGATCAGCGGCTTGACCTCTGGTGCCGTCAAGGGCTAAGCG
AAACAAAAGGTTTTATAACA

Downstream 100 bases:

>100_bases
TGGCAAAAGTCGAATTCAAAAACATCAAGAAATCCTACGATGATGTCGAGGTAGTGAAACACTTCGACTTCACGGTGCAA
GATGGTGAGTTTGTGGTTTT

Product: beta-glucosidase

Products: NA

Alternate protein names: Amygdalase; Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MNKFQLPQDSKLRSPEFLFGVATSSYQIEGGAQLGGRTPSIWDTFCNKPGAVDNADNGDVACDHFHLWKQDIEMIQGLGV
GAYRLSMAWPRIIPEDGKVNEEGLKFYEQIIDECHARGLKVFVTLYHWDLPQYLEDKGGWLNRETAYKFEEYAKVVSAYF
GDKIDSYATLNEPFCSAYLGYRWGEHAPGLKGEREGFLSAHHLMLAHGLAIPHMRKNAPNAMHGCVFNATPAYPYGEADI
GAAEYSDAEGYHWFMDPVLKGEYPQLVVKRQSHNMPMILEGDLDIIQTDLDFIGINFYTRCVVRYNEHGDIETVPQPEQE
HTFIGWEIHPQALTDLLLRLNDRYPNLPPLYITENGAAGDDHCIEGEVNDEQRVRYFQQHLVALDAAIKAGVDVDGYFAW
SLMDNFEWAYGYKQRFGIVHVDYQTQKRTLKASAIAYRNMLLDRAEENQ

Sequences:

>Translated_449_residues
MNKFQLPQDSKLRSPEFLFGVATSSYQIEGGAQLGGRTPSIWDTFCNKPGAVDNADNGDVACDHFHLWKQDIEMIQGLGV
GAYRLSMAWPRIIPEDGKVNEEGLKFYEQIIDECHARGLKVFVTLYHWDLPQYLEDKGGWLNRETAYKFEEYAKVVSAYF
GDKIDSYATLNEPFCSAYLGYRWGEHAPGLKGEREGFLSAHHLMLAHGLAIPHMRKNAPNAMHGCVFNATPAYPYGEADI
GAAEYSDAEGYHWFMDPVLKGEYPQLVVKRQSHNMPMILEGDLDIIQTDLDFIGINFYTRCVVRYNEHGDIETVPQPEQE
HTFIGWEIHPQALTDLLLRLNDRYPNLPPLYITENGAAGDDHCIEGEVNDEQRVRYFQQHLVALDAAIKAGVDVDGYFAW
SLMDNFEWAYGYKQRFGIVHVDYQTQKRTLKASAIAYRNMLLDRAEENQ
>Mature_449_residues
MNKFQLPQDSKLRSPEFLFGVATSSYQIEGGAQLGGRTPSIWDTFCNKPGAVDNADNGDVACDHFHLWKQDIEMIQGLGV
GAYRLSMAWPRIIPEDGKVNEEGLKFYEQIIDECHARGLKVFVTLYHWDLPQYLEDKGGWLNRETAYKFEEYAKVVSAYF
GDKIDSYATLNEPFCSAYLGYRWGEHAPGLKGEREGFLSAHHLMLAHGLAIPHMRKNAPNAMHGCVFNATPAYPYGEADI
GAAEYSDAEGYHWFMDPVLKGEYPQLVVKRQSHNMPMILEGDLDIIQTDLDFIGINFYTRCVVRYNEHGDIETVPQPEQE
HTFIGWEIHPQALTDLLLRLNDRYPNLPPLYITENGAAGDDHCIEGEVNDEQRVRYFQQHLVALDAAIKAGVDVDGYFAW
SLMDNFEWAYGYKQRFGIVHVDYQTQKRTLKASAIAYRNMLLDRAEENQ

Specific function: Unknown

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=467, Percent_Identity=35.117773019272, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI13273313, Length=467, Percent_Identity=33.4047109207709, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI110681710, Length=468, Percent_Identity=32.2649572649573, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI24497614, Length=458, Percent_Identity=32.5327510917031, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI28376633, Length=440, Percent_Identity=28.8636363636364, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI190360571, Length=93, Percent_Identity=37.6344086021505, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI2367174, Length=492, Percent_Identity=30.0813008130081, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI2367270, Length=431, Percent_Identity=31.554524361949, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789070, Length=415, Percent_Identity=29.1566265060241, Blast_Score=174, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17552856, Length=464, Percent_Identity=30.8189655172414, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17539390, Length=462, Percent_Identity=29.8701298701299, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21356577, Length=464, Percent_Identity=32.3275862068966, Blast_Score=244, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 51213; Mature: 51213

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFQLPQDSKLRSPEFLFGVATSSYQIEGGAQLGGRTPSIWDTFCNKPGAVDNADNGDV
CCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCE
ACDHFHLWKQDIEMIQGLGVGAYRLSMAWPRIIPEDGKVNEEGLKFYEQIIDECHARGLK
EEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
VFVTLYHWDLPQYLEDKGGWLNRETAYKFEEYAKVVSAYFGDKIDSYATLNEPFCSAYLG
EEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHC
YRWGEHAPGLKGEREGFLSAHHLMLAHGLAIPHMRKNAPNAMHGCVFNATPAYPYGEADI
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHCEEEECCCCCCCCCCCC
GAAEYSDAEGYHWFMDPVLKGEYPQLVVKRQSHNMPMILEGDLDIIQTDLDFIGINFYTR
CCCCCCCCCCEEEECCHHHCCCCCCEEEEECCCCCCEEEECCCCEEECCHHEEECCCEEE
CVVRYNEHGDIETVPQPEQEHTFIGWEIHPQALTDLLLRLNDRYPNLPPLYITENGAAGD
EEEEECCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
DHCIEGEVNDEQRVRYFQQHLVALDAAIKAGVDVDGYFAWSLMDNFEWAYGYKQRFGIVH
CCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCHHCCHHHHCCEEE
VDYQTQKRTLKASAIAYRNMLLDRAEENQ
EECHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKFQLPQDSKLRSPEFLFGVATSSYQIEGGAQLGGRTPSIWDTFCNKPGAVDNADNGDV
CCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCE
ACDHFHLWKQDIEMIQGLGVGAYRLSMAWPRIIPEDGKVNEEGLKFYEQIIDECHARGLK
EEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
VFVTLYHWDLPQYLEDKGGWLNRETAYKFEEYAKVVSAYFGDKIDSYATLNEPFCSAYLG
EEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHC
YRWGEHAPGLKGEREGFLSAHHLMLAHGLAIPHMRKNAPNAMHGCVFNATPAYPYGEADI
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHCEEEECCCCCCCCCCCC
GAAEYSDAEGYHWFMDPVLKGEYPQLVVKRQSHNMPMILEGDLDIIQTDLDFIGINFYTR
CCCCCCCCCCEEEECCHHHCCCCCCEEEEECCCCCCEEEECCCCEEECCHHEEECCCEEE
CVVRYNEHGDIETVPQPEQEHTFIGWEIHPQALTDLLLRLNDRYPNLPPLYITENGAAGD
EEEEECCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
DHCIEGEVNDEQRVRYFQQHLVALDAAIKAGVDVDGYFAWSLMDNFEWAYGYKQRFGIVH
CCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCHHCCHHHHCCEEE
VDYQTQKRTLKASAIAYRNMLLDRAEENQ
EECHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123813 [H]