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The map label for this gene is wzc [H]

Identifier: 156977875

GI number: 156977875

Start: 1803448

End: 1805598

Strand: Direct

Name: wzc [H]

Synonym: VIBHAR_06667

Alternate gene names: 156977875

Gene position: 1803448-1805598 (Clockwise)

Preceding gene: 156977874

Following gene: 156977876

Centisome position: 81.83

GC content: 42.77

Gene sequence:

>2151_bases
ATGGCTAACCACACTATAAGTTCATCTGCACCCACCGATGATGAAATCGATCTCGGTAAACTGTTTGGCATACTAATAGA
TGCGAAATGGTTCATCGTTGGCATTACACTTCTCTTTGCAACAATCGGTATTGCCGTTGCGTTGCTATCGACACCAATTT
ACAAAGCTGATGCCCTAATTCAGATCGAACAGAAAAGCTCCGGCGGTATTTCGGCGATGGTCGGCGATATGGGCGACCTT
TTTGCTGCTGAGTCTTCAGCAACGACTGAAATTGAGATCATCAAGTCACGTATGATCCTCGGTGATACCGTCGATAAATT
TAACCTAACAACAATTGCCACTCCGGAATACTTTCCTTTTGTTGGCAAAGGTTTGGCTCGAATCAATGGCACTCAAAATT
ACATTTCAGTATCAAGTTTCGAGATACCTCGCACCGCGCAAGGCTTCAGGCATCACCTTGTAGTGAGCGATGCAGAGAAA
GGTACTTTTGATCTGATGATTGAAGATAAAATTGTGCTATCTGGCGTTGTTGGTCAAACGATCGAAATGAATGGCTACCA
CATCAAAGTACGTGAACTGGTTGCGCAAAATGAAGACAGTTTTTCTATCGGAAAAATTAGCAAGCTTGATGCGATCAACC
GATTAGCTTCACAACTGTCTATTTCAGAACGTGGTGCGAAAACAGGTATTGTGTCACTGAGTATTGAAGGCGAATACCCT
GAGCGTAACCAACAAATCTTGAATGATGTCGTACAAAACTATTTCCTACAAAATGTGCGAAGAAATTCAGCAGAAGCAGA
ACAAAGCTTAAACTTCCTGAAAGATCACCTGCCAGAAATTAAAGATAAGCTTAACGGCTCAGAGGACGTATTGAATCGTT
TTAGACAAGAAAACGAATCGATCGACTTAAACCTTGAAGCACAATCAACACTCAAAGTGATGGTTGCTCTTGAAGCACAG
CTAAATGAACTGACCTTTAAAGAGAGTGAAATCAGTCAGAAGTTCACTCAAGACCACCCAGCATACAAATCACTATTGGA
TAAACGTCAGACACTACTGCAAGAAAAAGCTCGTTTAAACCGACAAGTACAGAAGTTGCCGAAGACACAACGTGAAGTGT
TGCGTATGACACGTGACGTTGAAGTGAACCAACAGATCTACATCCAGCTTCTAAACAAAGTTCAAGAGTTGAACATTATT
AAAGCAGGTACCGTTGGTAACGTACGTATTATCGATAGTGCGCAGTCTTACGCTATTCCAGTGAAGCCTAAAAAGCCTCT
TATTGTTGTTCTAGCAACACTATTAGGCGGAATGGTGGCCGTTGCTTTCGTTCTGGTCAAAACTGCTTTCCATCGCGGTG
TCACATCCCCAGATGAGATTGAACAAACGGGGATTTCCGTTTACGCAAGTGTTCCTAAGTCTGTACAACAACTGGAAGTC
GCTAACAAGCTTAAGCGCAAGGGTAACAAGGACCTACTGTTATTAGCAGAAGAAAACCCAGCGGACCTTTCGATTGAATC
ATTACGTGGACTTCGTACCAGCCTTCATTTTGCGATGATGGAAGCGAAAAACAACGTTCTAATGATCTCTGGACCTGCTC
CCTCAATTGGTAAAACATTCGTTTCAACTAACTTTGCAGCAGTTGCGGCGAAGACAGGCCAGAAGGTACTATTGGTTGAC
GCAGATATGCGTAAAGGTTATCTGCAACAATGTTTTGGCCTGGCGGCAGATAACGGCCTTTCTGACTTTTTAAGCGGTAA
GATTAGTCAAGATATGGTGATCAAGCCGACTAAAGTTGAGAACTTAGGTGTAATTACTCGTGGTCAAGTACCACCAAACC
CTTCTGAGCTTTTGATGCACCCACGATTTGCTGAGTTTGTAAAAAAAGCATCACAAGAGTATGACCTAGTGATCATCGAT
ACACCGCCAGTATTAGCAGTGACTGATCCTAGTATCGTTGGTGCGATTGCAGGTACCACTCTTATGGTTGCTCGATTTGA
CCAAACGACATCGAAAGAACTAGAAGTCGCTCGTAGCCGATTTGAACAATCGGGTGTCGAAGTAAAAGGCGTCATTCTTA
ATGCAATAGAGAAGAAAGCCGCAAGCTCATACGGTTATGGTTATTACAACTACGCTTACAAAAGTGAATAA

Upstream 100 bases:

>100_bases
CAGAGAAGCATTCGACCATGCGTTCTCACTGATTGAAAAGTCCGCTCATGCATGGGCAAAAAAAATATAACTTCAGACTA
CTTGGCGAAACATAAAAATA

Downstream 100 bases:

>100_bases
TCTAACTCCCCGTTGAAGTGAAAAGCCAAGCCCCGCAATTATCGCGGGGCTTTTTCAATAATTATCAAACTATTAGAAAT
CTAAGCGGTCACCTTTAGTA

Product: hypothetical protein

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 715

Protein sequence:

>716_residues
MANHTISSSAPTDDEIDLGKLFGILIDAKWFIVGITLLFATIGIAVALLSTPIYKADALIQIEQKSSGGISAMVGDMGDL
FAAESSATTEIEIIKSRMILGDTVDKFNLTTIATPEYFPFVGKGLARINGTQNYISVSSFEIPRTAQGFRHHLVVSDAEK
GTFDLMIEDKIVLSGVVGQTIEMNGYHIKVRELVAQNEDSFSIGKISKLDAINRLASQLSISERGAKTGIVSLSIEGEYP
ERNQQILNDVVQNYFLQNVRRNSAEAEQSLNFLKDHLPEIKDKLNGSEDVLNRFRQENESIDLNLEAQSTLKVMVALEAQ
LNELTFKESEISQKFTQDHPAYKSLLDKRQTLLQEKARLNRQVQKLPKTQREVLRMTRDVEVNQQIYIQLLNKVQELNII
KAGTVGNVRIIDSAQSYAIPVKPKKPLIVVLATLLGGMVAVAFVLVKTAFHRGVTSPDEIEQTGISVYASVPKSVQQLEV
ANKLKRKGNKDLLLLAEENPADLSIESLRGLRTSLHFAMMEAKNNVLMISGPAPSIGKTFVSTNFAAVAAKTGQKVLLVD
ADMRKGYLQQCFGLAADNGLSDFLSGKISQDMVIKPTKVENLGVITRGQVPPNPSELLMHPRFAEFVKKASQEYDLVIID
TPPVLAVTDPSIVGAIAGTTLMVARFDQTTSKELEVARSRFEQSGVEVKGVILNAIEKKAASSYGYGYYNYAYKSE

Sequences:

>Translated_716_residues
MANHTISSSAPTDDEIDLGKLFGILIDAKWFIVGITLLFATIGIAVALLSTPIYKADALIQIEQKSSGGISAMVGDMGDL
FAAESSATTEIEIIKSRMILGDTVDKFNLTTIATPEYFPFVGKGLARINGTQNYISVSSFEIPRTAQGFRHHLVVSDAEK
GTFDLMIEDKIVLSGVVGQTIEMNGYHIKVRELVAQNEDSFSIGKISKLDAINRLASQLSISERGAKTGIVSLSIEGEYP
ERNQQILNDVVQNYFLQNVRRNSAEAEQSLNFLKDHLPEIKDKLNGSEDVLNRFRQENESIDLNLEAQSTLKVMVALEAQ
LNELTFKESEISQKFTQDHPAYKSLLDKRQTLLQEKARLNRQVQKLPKTQREVLRMTRDVEVNQQIYIQLLNKVQELNII
KAGTVGNVRIIDSAQSYAIPVKPKKPLIVVLATLLGGMVAVAFVLVKTAFHRGVTSPDEIEQTGISVYASVPKSVQQLEV
ANKLKRKGNKDLLLLAEENPADLSIESLRGLRTSLHFAMMEAKNNVLMISGPAPSIGKTFVSTNFAAVAAKTGQKVLLVD
ADMRKGYLQQCFGLAADNGLSDFLSGKISQDMVIKPTKVENLGVITRGQVPPNPSELLMHPRFAEFVKKASQEYDLVIID
TPPVLAVTDPSIVGAIAGTTLMVARFDQTTSKELEVARSRFEQSGVEVKGVILNAIEKKAASSYGYGYYNYAYKSE
>Mature_715_residues
ANHTISSSAPTDDEIDLGKLFGILIDAKWFIVGITLLFATIGIAVALLSTPIYKADALIQIEQKSSGGISAMVGDMGDLF
AAESSATTEIEIIKSRMILGDTVDKFNLTTIATPEYFPFVGKGLARINGTQNYISVSSFEIPRTAQGFRHHLVVSDAEKG
TFDLMIEDKIVLSGVVGQTIEMNGYHIKVRELVAQNEDSFSIGKISKLDAINRLASQLSISERGAKTGIVSLSIEGEYPE
RNQQILNDVVQNYFLQNVRRNSAEAEQSLNFLKDHLPEIKDKLNGSEDVLNRFRQENESIDLNLEAQSTLKVMVALEAQL
NELTFKESEISQKFTQDHPAYKSLLDKRQTLLQEKARLNRQVQKLPKTQREVLRMTRDVEVNQQIYIQLLNKVQELNIIK
AGTVGNVRIIDSAQSYAIPVKPKKPLIVVLATLLGGMVAVAFVLVKTAFHRGVTSPDEIEQTGISVYASVPKSVQQLEVA
NKLKRKGNKDLLLLAEENPADLSIESLRGLRTSLHFAMMEAKNNVLMISGPAPSIGKTFVSTNFAAVAAKTGQKVLLVDA
DMRKGYLQQCFGLAADNGLSDFLSGKISQDMVIKPTKVENLGVITRGQVPPNPSELLMHPRFAEFVKKASQEYDLVIIDT
PPVLAVTDPSIVGAIAGTTLMVARFDQTTSKELEVARSRFEQSGVEVKGVILNAIEKKAASSYGYGYYNYAYKSE

Specific function: Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg [H]

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=710, Percent_Identity=48.169014084507, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1787216, Length=701, Percent_Identity=44.9358059914408, Blast_Score=620, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 78734; Mature: 78602

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHTISSSAPTDDEIDLGKLFGILIDAKWFIVGITLLFATIGIAVALLSTPIYKADALI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
QIEQKSSGGISAMVGDMGDLFAAESSATTEIEIIKSRMILGDTVDKFNLTTIATPEYFPF
EEECCCCCCCEEHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
VGKGLARINGTQNYISVSSFEIPRTAQGFRHHLVVSDAEKGTFDLMIEDKIVLSGVVGQT
HHCHHHHCCCCCCEEEEECCCCCCHHHHHHEEEEEECCCCCEEEEEEECCEEEEHHCCCE
IEMNGYHIKVRELVAQNEDSFSIGKISKLDAINRLASQLSISERGAKTGIVSLSIEGEYP
EECCCEEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
ERNQQILNDVVQNYFLQNVRRNSAEAEQSLNFLKDHLPEIKDKLNGSEDVLNRFRQENES
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
IDLNLEAQSTLKVMVALEAQLNELTFKESEISQKFTQDHPAYKSLLDKRQTLLQEKARLN
EEEEEEHHHHEEEEHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQVQKLPKTQREVLRMTRDVEVNQQIYIQLLNKVQELNIIKAGTVGNVRIIDSAQSYAIP
HHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEC
VKPKKPLIVVLATLLGGMVAVAFVLVKTAFHRGVTSPDEIEQTGISVYASVPKSVQQLEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEHHHHHHHHHHH
ANKLKRKGNKDLLLLAEENPADLSIESLRGLRTSLHFAMMEAKNNVLMISGPAPSIGKTF
HHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHH
VSTNFAAVAAKTGQKVLLVDADMRKGYLQQCFGLAADNGLSDFLSGKISQDMVIKPTKVE
HHCCHHEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCC
NLGVITRGQVPPNPSELLMHPRFAEFVKKASQEYDLVIIDTPPVLAVTDPSIVGAIAGTT
CCCEEEECCCCCCHHHHHCCCHHHHHHHHCCCCCCEEEECCCCEEEECCCHHHHHHHHHE
LMVARFDQTTSKELEVARSRFEQSGVEVKGVILNAIEKKAASSYGYGYYNYAYKSE
EEEEECCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCC
>Mature Secondary Structure 
ANHTISSSAPTDDEIDLGKLFGILIDAKWFIVGITLLFATIGIAVALLSTPIYKADALI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
QIEQKSSGGISAMVGDMGDLFAAESSATTEIEIIKSRMILGDTVDKFNLTTIATPEYFPF
EEECCCCCCCEEHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
VGKGLARINGTQNYISVSSFEIPRTAQGFRHHLVVSDAEKGTFDLMIEDKIVLSGVVGQT
HHCHHHHCCCCCCEEEEECCCCCCHHHHHHEEEEEECCCCCEEEEEEECCEEEEHHCCCE
IEMNGYHIKVRELVAQNEDSFSIGKISKLDAINRLASQLSISERGAKTGIVSLSIEGEYP
EECCCEEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
ERNQQILNDVVQNYFLQNVRRNSAEAEQSLNFLKDHLPEIKDKLNGSEDVLNRFRQENES
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
IDLNLEAQSTLKVMVALEAQLNELTFKESEISQKFTQDHPAYKSLLDKRQTLLQEKARLN
EEEEEEHHHHEEEEHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQVQKLPKTQREVLRMTRDVEVNQQIYIQLLNKVQELNIIKAGTVGNVRIIDSAQSYAIP
HHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEC
VKPKKPLIVVLATLLGGMVAVAFVLVKTAFHRGVTSPDEIEQTGISVYASVPKSVQQLEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEHHHHHHHHHHH
ANKLKRKGNKDLLLLAEENPADLSIESLRGLRTSLHFAMMEAKNNVLMISGPAPSIGKTF
HHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHH
VSTNFAAVAAKTGQKVLLVDADMRKGYLQQCFGLAADNGLSDFLSGKISQDMVIKPTKVE
HHCCHHEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCC
NLGVITRGQVPPNPSELLMHPRFAEFVKKASQEYDLVIIDTPPVLAVTDPSIVGAIAGTT
CCCEEEECCCCCCHHHHHCCCHHHHHHHHCCCCCCEEEECCCCEEEECCCHHHHHHHHHE
LMVARFDQTTSKELEVARSRFEQSGVEVKGVILNAIEKKAASSYGYGYYNYAYKSE
EEEEECCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]