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The map label for this gene is dacC [H]

Identifier: 156977862

GI number: 156977862

Start: 1790688

End: 1791854

Strand: Reverse

Name: dacC [H]

Synonym: VIBHAR_06653

Alternate gene names: 156977862

Gene position: 1791854-1790688 (Counterclockwise)

Preceding gene: 156977864

Following gene: 156977861

Centisome position: 81.3

GC content: 48.59

Gene sequence:

>1167_bases
ATGAACACGTCACTAACCCGAATCACGCTCGCTTGTTTATTACTACAGACCATCAGTGCCCCTGCATTGGCAGTCGTAAC
GCCGAATCCGCCTCAGTTGCAGGCAAAAGGCTATGTGTTAATGGACTTTCAGTCCGGTGCCATCATAGCGGAGCAAAACG
CGCGTGCCGGATTAGCCCCTGCCAGTTTAACTAAGTTGATGACCGCTTACGTCGTGGGGCAAGAAATCAAATCTGGGCGG
CTCCAATGGGACGATAAAGTGACGGTGAGTGAGAATGCATGGTCAGCTAAATTTCCAGACTCCTCCAAAATGTTTATCCA
ACCCAAAGATGAAATCACCGTCGCCAACCTAATGCGTGGTGTGATCATTCAATCTGGTAATGATGCTTGTGTGGCGCTCG
CCGAACATGTTGCCGGTGGTGAAGGGGCGTTTGTTGCGTTGATGAATGGTTGGGCAGATAAACTCAGCTTGAACGATACC
TACTTCGTTAACTCGCATGGTCTGGATAGCGAGGGCATTCAAACTTCTCCTAATGACATGGCGACGCTGATGCAATCCAT
CATCAATGACGTGCCTGAAGTCTATGCGCTCTATAGTGAGAAGGTATTCAAGTGGAACAAGATCACCCAATACAACCGCA
ATAAGTTGCTATGGGACAAATCGATGGATGTCGATGGAGGTAAAACGGGCTACACCAGCAATGCGGGGTACAGTTTGGTG
AGCTCTGCTAAACAAGGAAAGATGCGATTGATCTCGGTAGTGATGGGGACGCCAAGTAAACAATCGCGAATCACCCAGTC
TAAGAACTTACTCAGTTACGGCTTCCGTTTTTATGACACCAAACAAGTGGCAAAACAGGGAGAGGTGCAGGCGAGTGCAA
AAGTATGGAAAGGCAATGTCAGTGAGATTGATTTGGGCTTCGCTCAAGATGCGTACCTGACGCTGCCTCGTTCCCTAACC
GCTGGTTTAGACAAGAGCGTGGTCGTGAATGAACCGTTGATAGCACCCATCGCGAAAGGCGATGTGGTTGGTAAAGTCGT
GTGGAAGAGTGACGATCAAACAGTAGCAAGCTATCCATTGGTAAGTAACCAAGCGGTGGAAGAGGGCTCATGGATTGGTA
AGTTATGGGACAGTTTGGTGCTGTGGGTGAAATCGTTGTTTAATTAG

Upstream 100 bases:

>100_bases
CTGAGTGAACTATGATCTGATAGGTGCAGTTTAGACTTCACTGTCTTACCGTTTTTATGAAACGAGACAATTGGCGGTCA
TTGACCATGGAGGATGCTTG

Downstream 100 bases:

>100_bases
CGTCAGATAAATTTTCAAATTTATTTTGAAAAAGTTATTCGCTTAGGTCGATTTTTCTCTTGGGTGGAAAGGAGTAGATT
GTTGGAATATAGAAAAACAC

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNTSLTRITLACLLLQTISAPALAVVTPNPPQLQAKGYVLMDFQSGAIIAEQNARAGLAPASLTKLMTAYVVGQEIKSGR
LQWDDKVTVSENAWSAKFPDSSKMFIQPKDEITVANLMRGVIIQSGNDACVALAEHVAGGEGAFVALMNGWADKLSLNDT
YFVNSHGLDSEGIQTSPNDMATLMQSIINDVPEVYALYSEKVFKWNKITQYNRNKLLWDKSMDVDGGKTGYTSNAGYSLV
SSAKQGKMRLISVVMGTPSKQSRITQSKNLLSYGFRFYDTKQVAKQGEVQASAKVWKGNVSEIDLGFAQDAYLTLPRSLT
AGLDKSVVVNEPLIAPIAKGDVVGKVVWKSDDQTVASYPLVSNQAVEEGSWIGKLWDSLVLWVKSLFN

Sequences:

>Translated_388_residues
MNTSLTRITLACLLLQTISAPALAVVTPNPPQLQAKGYVLMDFQSGAIIAEQNARAGLAPASLTKLMTAYVVGQEIKSGR
LQWDDKVTVSENAWSAKFPDSSKMFIQPKDEITVANLMRGVIIQSGNDACVALAEHVAGGEGAFVALMNGWADKLSLNDT
YFVNSHGLDSEGIQTSPNDMATLMQSIINDVPEVYALYSEKVFKWNKITQYNRNKLLWDKSMDVDGGKTGYTSNAGYSLV
SSAKQGKMRLISVVMGTPSKQSRITQSKNLLSYGFRFYDTKQVAKQGEVQASAKVWKGNVSEIDLGFAQDAYLTLPRSLT
AGLDKSVVVNEPLIAPIAKGDVVGKVVWKSDDQTVASYPLVSNQAVEEGSWIGKLWDSLVLWVKSLFN
>Mature_388_residues
MNTSLTRITLACLLLQTISAPALAVVTPNPPQLQAKGYVLMDFQSGAIIAEQNARAGLAPASLTKLMTAYVVGQEIKSGR
LQWDDKVTVSENAWSAKFPDSSKMFIQPKDEITVANLMRGVIIQSGNDACVALAEHVAGGEGAFVALMNGWADKLSLNDT
YFVNSHGLDSEGIQTSPNDMATLMQSIINDVPEVYALYSEKVFKWNKITQYNRNKLLWDKSMDVDGGKTGYTSNAGYSLV
SSAKQGKMRLISVVMGTPSKQSRITQSKNLLSYGFRFYDTKQVAKQGEVQASAKVWKGNVSEIDLGFAQDAYLTLPRSLT
AGLDKSVVVNEPLIAPIAKGDVVGKVVWKSDDQTVASYPLVSNQAVEEGSWIGKLWDSLVLWVKSLFN

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=370, Percent_Identity=45.4054054054054, Blast_Score=336, Evalue=1e-93,
Organism=Escherichia coli, GI1786851, Length=393, Percent_Identity=43.765903307888, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI87082022, Length=355, Percent_Identity=44.2253521126761, Blast_Score=307, Evalue=6e-85,
Organism=Escherichia coli, GI87082054, Length=219, Percent_Identity=26.027397260274, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42221; Mature: 42221

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSLTRITLACLLLQTISAPALAVVTPNPPQLQAKGYVLMDFQSGAIIAEQNARAGLAP
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEEECCCEEEEECCCCCCCCH
ASLTKLMTAYVVGQEIKSGRLQWDDKVTVSENAWSAKFPDSSKMFIQPKDEITVANLMRG
HHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCCCCCCCCCEEECCCCCEEHHHHHHH
VIIQSGNDACVALAEHVAGGEGAFVALMNGWADKLSLNDTYFVNSHGLDSEGIQTSPNDM
HEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHEECCCEEEEECCCCCCCCCCCCCHHH
ATLMQSIINDVPEVYALYSEKVFKWNKITQYNRNKLLWDKSMDVDGGKTGYTSNAGYSLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
SSAKQGKMRLISVVMGTPSKQSRITQSKNLLSYGFRFYDTKQVAKQGEVQASAKVWKGNV
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEECHHHHHHCCCCCCHHHHCCCCC
SEIDLGFAQDAYLTLPRSLTAGLDKSVVVNEPLIAPIAKGDVVGKVVWKSDDQTVASYPL
CEEECCCCCCCEEECCHHHHCCCCCCEEECCCCCCEECCCCEEEEEEECCCCCEEEECCC
VSNQAVEEGSWIGKLWDSLVLWVKSLFN
CCCCCHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTSLTRITLACLLLQTISAPALAVVTPNPPQLQAKGYVLMDFQSGAIIAEQNARAGLAP
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEEECCCEEEEECCCCCCCCH
ASLTKLMTAYVVGQEIKSGRLQWDDKVTVSENAWSAKFPDSSKMFIQPKDEITVANLMRG
HHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCCCCCCCCCEEECCCCCEEHHHHHHH
VIIQSGNDACVALAEHVAGGEGAFVALMNGWADKLSLNDTYFVNSHGLDSEGIQTSPNDM
HEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHEECCCEEEEECCCCCCCCCCCCCHHH
ATLMQSIINDVPEVYALYSEKVFKWNKITQYNRNKLLWDKSMDVDGGKTGYTSNAGYSLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
SSAKQGKMRLISVVMGTPSKQSRITQSKNLLSYGFRFYDTKQVAKQGEVQASAKVWKGNV
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEECHHHHHHCCCCCCHHHHCCCCC
SEIDLGFAQDAYLTLPRSLTAGLDKSVVVNEPLIAPIAKGDVVGKVVWKSDDQTVASYPL
CEEECCCCCCCEEECCHHHHCCCCCCEEECCCCCCEECCCCEEEEEEECCCCCEEEECCC
VSNQAVEEGSWIGKLWDSLVLWVKSLFN
CCCCCHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]