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The map label for this gene is baeR [H]

Identifier: 156977839

GI number: 156977839

Start: 1769664

End: 1770458

Strand: Reverse

Name: baeR [H]

Synonym: VIBHAR_06627

Alternate gene names: 156977839

Gene position: 1770458-1769664 (Counterclockwise)

Preceding gene: 156977841

Following gene: 156977837

Centisome position: 80.33

GC content: 44.91

Gene sequence:

>795_bases
TTGCTGTATCAATCCGATAGCCTTTGCATCAAAGTAAGGGATAACCCCAACACAAAAATAAATATCGTCAACGAGGTTAA
GACAATGAGCGACCAATCAACCGTCGTTATTATTGAGGATGAATCTGCCATTGCAGAAAACCTCATTCATGTATTAGAGA
TGGATGGTTATCATGCGGCGTGGTTTGCAACGGCAGGCGAGGGCTTAGCCTTTTTGCAGCAAAAACCAGCAGCGTTACTT
GTGTTGGATGTTGGTTTACCGGATGGCAATGGTTTTGAATTGTGCAAAACCATCCGTGAGTTTTCTGATCTTCCCATTAT
CTTTCTCACCGCAAGAAGTGATGAAATTGACCGCGTAGTCGGCTTAGAGATTGGTGCGGATGATTACGTGACTAAGCCTT
TTAGTCCGCGTGAAATGTTGGCTCGCATTAAACTTCGAATCAAAGCTAAAGCGCCGATGATGGAGCACAAACCGGAGTCT
GTGGCTGTTCCAGAACAACCTCAATTGAATCATGATTTGGTTGCACAAAACTTCGACTATGGTGTTGGCGGGCAAATGCT
TGGGTTAACTGCGGTGGAGTTCAAGATCCTCAATAAACTGATTTCTGTCTCTTCCAATGTAGTGAGTCGAGAGCAGCTTA
TGATCGCTGCTGATATGGCGCCAGAAGCCGCGTACGAGCGCAATATCGATACCCACATCAAAGCGATTCGTCACAAGTTG
AAGCCATTTGAGATGTCTGAACGCATCTGTACTAAGCGTGGCTTTGGGTACTTTTACTGCATTAAAGGTGAATGA

Upstream 100 bases:

>100_bases
AATCATTGTATTCGAAAATGTAGTGAGTCATCAGTGCGGGTGATAAGTTCCATTGTTTGAATGAATTTTGTTTTATTAAT
ATCTCTCGCGGATTTTGCCA

Downstream 100 bases:

>100_bases
TGAATCGCTGGCCGAAGATCCCGCTTGGACTCAGACTGTTTTTTCTCTACTTCATCTTAGTCGGAATGACGGCTTACATG
GTGAGCAAAACGGTTGTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLYQSDSLCIKVRDNPNTKINIVNEVKTMSDQSTVVIIEDESAIAENLIHVLEMDGYHAAWFATAGEGLAFLQQKPAALL
VLDVGLPDGNGFELCKTIREFSDLPIIFLTARSDEIDRVVGLEIGADDYVTKPFSPREMLARIKLRIKAKAPMMEHKPES
VAVPEQPQLNHDLVAQNFDYGVGGQMLGLTAVEFKILNKLISVSSNVVSREQLMIAADMAPEAAYERNIDTHIKAIRHKL
KPFEMSERICTKRGFGYFYCIKGE

Sequences:

>Translated_264_residues
MLYQSDSLCIKVRDNPNTKINIVNEVKTMSDQSTVVIIEDESAIAENLIHVLEMDGYHAAWFATAGEGLAFLQQKPAALL
VLDVGLPDGNGFELCKTIREFSDLPIIFLTARSDEIDRVVGLEIGADDYVTKPFSPREMLARIKLRIKAKAPMMEHKPES
VAVPEQPQLNHDLVAQNFDYGVGGQMLGLTAVEFKILNKLISVSSNVVSREQLMIAADMAPEAAYERNIDTHIKAIRHKL
KPFEMSERICTKRGFGYFYCIKGE
>Mature_264_residues
MLYQSDSLCIKVRDNPNTKINIVNEVKTMSDQSTVVIIEDESAIAENLIHVLEMDGYHAAWFATAGEGLAFLQQKPAALL
VLDVGLPDGNGFELCKTIREFSDLPIIFLTARSDEIDRVVGLEIGADDYVTKPFSPREMLARIKLRIKAKAPMMEHKPES
VAVPEQPQLNHDLVAQNFDYGVGGQMLGLTAVEFKILNKLISVSSNVVSREQLMIAADMAPEAAYERNIDTHIKAIRHKL
KPFEMSERICTKRGFGYFYCIKGE

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=35.2941176470588, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=39.1304347826087, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=34.051724137931, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789809, Length=245, Percent_Identity=31.8367346938775, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=34.061135371179, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=30, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=30.5084745762712, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=33.1932773109244, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=30.1310043668122, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=28.8793103448276, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=29.5154185022026, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=28.1385281385281, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29502; Mature: 29502

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYQSDSLCIKVRDNPNTKINIVNEVKTMSDQSTVVIIEDESAIAENLIHVLEMDGYHAA
CCCCCCCEEEEEECCCCCEEEEEEHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEE
WFATAGEGLAFLQQKPAALLVLDVGLPDGNGFELCKTIREFSDLPIIFLTARSDEIDRVV
EEEECCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEE
GLEIGADDYVTKPFSPREMLARIKLRIKAKAPMMEHKPESVAVPEQPQLNHDLVAQNFDY
EEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHCCCCC
GVGGQMLGLTAVEFKILNKLISVSSNVVSREQLMIAADMAPEAAYERNIDTHIKAIRHKL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCHHHHHCCHHHHHHHHHHHC
KPFEMSERICTKRGFGYFYCIKGE
CCCCHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MLYQSDSLCIKVRDNPNTKINIVNEVKTMSDQSTVVIIEDESAIAENLIHVLEMDGYHAA
CCCCCCCEEEEEECCCCCEEEEEEHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEE
WFATAGEGLAFLQQKPAALLVLDVGLPDGNGFELCKTIREFSDLPIIFLTARSDEIDRVV
EEEECCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEE
GLEIGADDYVTKPFSPREMLARIKLRIKAKAPMMEHKPESVAVPEQPQLNHDLVAQNFDY
EEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHCCCCC
GVGGQMLGLTAVEFKILNKLISVSSNVVSREQLMIAADMAPEAAYERNIDTHIKAIRHKL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCHHHHHCCHHHHHHHHHHHC
KPFEMSERICTKRGFGYFYCIKGE
CCCCHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]