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The map label for this gene is gmr [H]

Identifier: 156977743

GI number: 156977743

Start: 1682673

End: 1683689

Strand: Direct

Name: gmr [H]

Synonym: VIBHAR_06531

Alternate gene names: 156977743

Gene position: 1682673-1683689 (Clockwise)

Preceding gene: 156977741

Following gene: 156977744

Centisome position: 76.35

GC content: 41.99

Gene sequence:

>1017_bases
ATGGACAGAACGCAGTTCACCAGAATTTTTACGCGCTACTACATGCGCTCAACAAGTTTGGGGATTCTTATTACCCTATT
CGCTTGTGCAATCAGAGGGGTTGATTATGTTGTATACCTTCCTTATGCATTATCCGCGGGAGTTTGTTTTACCTACCTCT
GGGTGGGCAAAGCATTCGCACTCGAACAAAAACAGCGCTCAGTTGTTATTGCACTGATCCTCGGATATACCCTCACATTT
TATTTGTACTACTTCTTAGGCGGACACTTTCTTTTTTCTTCCTTGGTTACAGTCAATATTCTTCTCACTTTGATTGAGTT
TGGCGTACTTTGGTCGTCAATCACATATGTCCTATCAATGGCTATTTGCTTTAACATTGATTTGATAACCGCGGGTAACG
ACCCGTTTAAACTACAAGGTTTAAGTGAGTTTTCCATTCGGAGTACGTTTCTGTACTTGTTCAACCTATTTATTTACAAG
GGCTTGCGCTCAATTGAAAGTTATTGGCACAGCGCTTGGCAAACGCAATATGAACAAGTTGAAAAACTAGAAAGACTGCT
CGAGATAGATGAGCTAACAGGCTGCTACTCTCGCTTCAAAGGCAATCAGTTGATAGAGCAACAGATTCAACGAGCTCAAC
CGTTCACTTTGCTATATATCGACTTAGATGGCTTTAAAGCCGTGAATGACGAATTTGGTCACGACGCTGGAGACAAAGTA
CTGCGTATCACTGCGCAACGTATTTTGAACATGCTGCACAACGACCAATTCGCCACAAGAATTGGCGGTGACGAGTTCAT
TCTTTGCTTACCTGAGCTCGAAAATACAAAGGATTTAGAACAGTTTCAGTCTTTGCTACATCAAGCATGCAGTGCACCTA
TTTTTATCCATTTTCAAAACGTTCACATCGGTTTGAGTGTTGGCGTTGCTCGCTTCCCTTATGAGGGAAGCTCTAGTGAC
ACCTTAATCCAACATGCAGACCAAATGATGTACCTCACTAAAAGATCAAGAACATAG

Upstream 100 bases:

>100_bases
GATGCCATTTATTTGTTTCTCACGTTCTCCATTCACACTCACCCCATACGGACTCCTCTCGCTAACTGCCCATTATTTGC
TGTTCCTTTGAGACATAACT

Downstream 100 bases:

>100_bases
AGTTTTGGCTCATTCTGAGCCGCTTCGAAGCAATTAAAAATATAATGAGTTCAGGACGTAGATATATGGTTAACAAGTTA
GAATTTTCGCACGCAGTTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MDRTQFTRIFTRYYMRSTSLGILITLFACAIRGVDYVVYLPYALSAGVCFTYLWVGKAFALEQKQRSVVIALILGYTLTF
YLYYFLGGHFLFSSLVTVNILLTLIEFGVLWSSITYVLSMAICFNIDLITAGNDPFKLQGLSEFSIRSTFLYLFNLFIYK
GLRSIESYWHSAWQTQYEQVEKLERLLEIDELTGCYSRFKGNQLIEQQIQRAQPFTLLYIDLDGFKAVNDEFGHDAGDKV
LRITAQRILNMLHNDQFATRIGGDEFILCLPELENTKDLEQFQSLLHQACSAPIFIHFQNVHIGLSVGVARFPYEGSSSD
TLIQHADQMMYLTKRSRT

Sequences:

>Translated_338_residues
MDRTQFTRIFTRYYMRSTSLGILITLFACAIRGVDYVVYLPYALSAGVCFTYLWVGKAFALEQKQRSVVIALILGYTLTF
YLYYFLGGHFLFSSLVTVNILLTLIEFGVLWSSITYVLSMAICFNIDLITAGNDPFKLQGLSEFSIRSTFLYLFNLFIYK
GLRSIESYWHSAWQTQYEQVEKLERLLEIDELTGCYSRFKGNQLIEQQIQRAQPFTLLYIDLDGFKAVNDEFGHDAGDKV
LRITAQRILNMLHNDQFATRIGGDEFILCLPELENTKDLEQFQSLLHQACSAPIFIHFQNVHIGLSVGVARFPYEGSSSD
TLIQHADQMMYLTKRSRT
>Mature_338_residues
MDRTQFTRIFTRYYMRSTSLGILITLFACAIRGVDYVVYLPYALSAGVCFTYLWVGKAFALEQKQRSVVIALILGYTLTF
YLYYFLGGHFLFSSLVTVNILLTLIEFGVLWSSITYVLSMAICFNIDLITAGNDPFKLQGLSEFSIRSTFLYLFNLFIYK
GLRSIESYWHSAWQTQYEQVEKLERLLEIDELTGCYSRFKGNQLIEQQIQRAQPFTLLYIDLDGFKAVNDEFGHDAGDKV
LRITAQRILNMLHNDQFATRIGGDEFILCLPELENTKDLEQFQSLLHQACSAPIFIHFQNVHIGLSVGVARFPYEGSSSD
TLIQHADQMMYLTKRSRT

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=156, Percent_Identity=38.4615384615385, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=29.6969696969697, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082007, Length=153, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787802, Length=245, Percent_Identity=24.0816326530612, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=34.8387096774194, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788381, Length=123, Percent_Identity=36.5853658536585, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081881, Length=227, Percent_Identity=29.5154185022026, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787262, Length=193, Percent_Identity=22.7979274611399, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081977, Length=124, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=26.0606060606061, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787816, Length=151, Percent_Identity=29.8013245033113, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 38930; Mature: 38930

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTQFTRIFTRYYMRSTSLGILITLFACAIRGVDYVVYLPYALSAGVCFTYLWVGKAFA
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHH
LEQKQRSVVIALILGYTLTFYLYYFLGGHFLFSSLVTVNILLTLIEFGVLWSSITYVLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AICFNIDLITAGNDPFKLQGLSEFSIRSTFLYLFNLFIYKGLRSIESYWHSAWQTQYEQV
HHHHCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLERLLEIDELTGCYSRFKGNQLIEQQIQRAQPFTLLYIDLDGFKAVNDEFGHDAGDKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCHHCHHCCCCCCHHH
LRITAQRILNMLHNDQFATRIGGDEFILCLPELENTKDLEQFQSLLHQACSAPIFIHFQN
HHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
VHIGLSVGVARFPYEGSSSDTLIQHADQMMYLTKRSRT
EEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDRTQFTRIFTRYYMRSTSLGILITLFACAIRGVDYVVYLPYALSAGVCFTYLWVGKAFA
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHH
LEQKQRSVVIALILGYTLTFYLYYFLGGHFLFSSLVTVNILLTLIEFGVLWSSITYVLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AICFNIDLITAGNDPFKLQGLSEFSIRSTFLYLFNLFIYKGLRSIESYWHSAWQTQYEQV
HHHHCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLERLLEIDELTGCYSRFKGNQLIEQQIQRAQPFTLLYIDLDGFKAVNDEFGHDAGDKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCHHCHHCCCCCCHHH
LRITAQRILNMLHNDQFATRIGGDEFILCLPELENTKDLEQFQSLLHQACSAPIFIHFQN
HHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
VHIGLSVGVARFPYEGSSSDTLIQHADQMMYLTKRSRT
EEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]