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The map label for this gene is lysN [H]

Identifier: 156977684

GI number: 156977684

Start: 1628792

End: 1629940

Strand: Direct

Name: lysN [H]

Synonym: VIBHAR_06472

Alternate gene names: 156977684

Gene position: 1628792-1629940 (Clockwise)

Preceding gene: 156977675

Following gene: 156977686

Centisome position: 73.9

GC content: 48.04

Gene sequence:

>1149_bases
ATGGAAATCGCACAGTCACTACAACATGTAAAGTCATCGTACATTCGAGAGATCCTCGCTGCCGCTAGCGATAAAAACGT
CATCTCGCTTGCTGGCGGTTTGCCCGATGAAAAGACCTTCCCTATCGACTTAATGAAGCCGACGCTAGAAAACTTGGCAA
ACATGCCTGAAGTTTTCCAATACGGCTCAACAGCAGGCTACGCGCCACTGCTAGAGTTCCTAAACGGCTACTTCAAACTG
CCTGAAACACACGCCGCAATGATTACTACAGGCTCTCAGCAAGGCCTAGATCTGATTGCACGTGCTTATGTAAACCCAGG
TGATAAAGTCGTGATGGAGGCACCAAGCTACCTTGGTGCAATGCAGGTGTTTGGTTTGGTTCAGGCGGACATCGTGACTG
TCTCTCAAACAGAATTTGGTCCAAACCTTGAAGAGCTAGAGCAATGCTTTGCAGAACAAAAACCGAAGATGTTCTACGCT
GTACCCGATTTCCATAACCCAACAGGGGTGTGCTGGGCACTAGAAACGCGTCAAAAAGTTGCAGAGCTTTGTATTCAATA
CAACGTCGCTTTTATTGAAGACGCGCCTTACCGTGAGTTGCGTTTCTCTGGTGAAGCACTGCCGCTTGTCTCTGATTTCT
GTCCTCAGCATTCTATCGTGCTGCGTTCATTCTCTAAGATCGCTTCTCCGGGTCTTCGCATTGGTGTGGTGACGGGTAAA
AGCAGTTATCTAGAACCGCTGATTAAAATCAAACAGGGTGCGGATCTGCATTCCAGCGTACCAATGCAAGCACTGTTGCA
CGGTCTGCTTCAACACGATAACTTTGAAACCCACATCAGCACCATTTGTGAGCTCTACAAGTCGCGTTACGATGTCATGT
ACGCAGAGCTAGAAAAGCAGCTTCCTAGCAATTGTGTATTGAAGCCCGTTGACGGTGGCATGTTTGTATGGGTGGAAATT
CCAGAATGCGATACCTTTGAACTAGCAAAATCATTGCTTGCGAACGGTGTGGCTGTTGTACCTAGCCCAGTGTTCTATCC
AGAAGGATCAGAAGTAAAAGCAGCGCTGCGCCTCAACTTCACTAACGCAACGCCTGAAGAGCTCAAAGTTGCCGTGACTC
GTTTAGCCGACGTACTGAACGCACTGTAA

Upstream 100 bases:

>100_bases
GACATGTTTAACAGCATATATGGACACACCAAGTTTAACAATTCCCATATAATATCTTTCAACTAAAACCAAAATTAAAA
AAATACGAGAAGCACAACGC

Downstream 100 bases:

>100_bases
TATAAATTACACCTTAGAATCCAAATACCTGCCTTTGAGATGCGAATTAAGTCTCGAAGGCAGCGTTTCAAAAAGTTCCC
CAAAAAATTTATTTTTTTCT

Product: aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MEIAQSLQHVKSSYIREILAAASDKNVISLAGGLPDEKTFPIDLMKPTLENLANMPEVFQYGSTAGYAPLLEFLNGYFKL
PETHAAMITTGSQQGLDLIARAYVNPGDKVVMEAPSYLGAMQVFGLVQADIVTVSQTEFGPNLEELEQCFAEQKPKMFYA
VPDFHNPTGVCWALETRQKVAELCIQYNVAFIEDAPYRELRFSGEALPLVSDFCPQHSIVLRSFSKIASPGLRIGVVTGK
SSYLEPLIKIKQGADLHSSVPMQALLHGLLQHDNFETHISTICELYKSRYDVMYAELEKQLPSNCVLKPVDGGMFVWVEI
PECDTFELAKSLLANGVAVVPSPVFYPEGSEVKAALRLNFTNATPEELKVAVTRLADVLNAL

Sequences:

>Translated_382_residues
MEIAQSLQHVKSSYIREILAAASDKNVISLAGGLPDEKTFPIDLMKPTLENLANMPEVFQYGSTAGYAPLLEFLNGYFKL
PETHAAMITTGSQQGLDLIARAYVNPGDKVVMEAPSYLGAMQVFGLVQADIVTVSQTEFGPNLEELEQCFAEQKPKMFYA
VPDFHNPTGVCWALETRQKVAELCIQYNVAFIEDAPYRELRFSGEALPLVSDFCPQHSIVLRSFSKIASPGLRIGVVTGK
SSYLEPLIKIKQGADLHSSVPMQALLHGLLQHDNFETHISTICELYKSRYDVMYAELEKQLPSNCVLKPVDGGMFVWVEI
PECDTFELAKSLLANGVAVVPSPVFYPEGSEVKAALRLNFTNATPEELKVAVTRLADVLNAL
>Mature_382_residues
MEIAQSLQHVKSSYIREILAAASDKNVISLAGGLPDEKTFPIDLMKPTLENLANMPEVFQYGSTAGYAPLLEFLNGYFKL
PETHAAMITTGSQQGLDLIARAYVNPGDKVVMEAPSYLGAMQVFGLVQADIVTVSQTEFGPNLEELEQCFAEQKPKMFYA
VPDFHNPTGVCWALETRQKVAELCIQYNVAFIEDAPYRELRFSGEALPLVSDFCPQHSIVLRSFSKIASPGLRIGVVTGK
SSYLEPLIKIKQGADLHSSVPMQALLHGLLQHDNFETHISTICELYKSRYDVMYAELEKQLPSNCVLKPVDGGMFVWVEI
PECDTFELAKSLLANGVAVVPSPVFYPEGSEVKAALRLNFTNATPEELKVAVTRLADVLNAL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=391, Percent_Identity=30.1790281329923, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI33469970, Length=391, Percent_Identity=30.1790281329923, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI56713256, Length=349, Percent_Identity=23.7822349570201, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI56713254, Length=349, Percent_Identity=23.7822349570201, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787710, Length=379, Percent_Identity=26.6490765171504, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788722, Length=346, Percent_Identity=27.4566473988439, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790797, Length=376, Percent_Identity=23.4042553191489, Blast_Score=98, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=184, Percent_Identity=25, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356535, Length=371, Percent_Identity=25.6064690026954, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 42083; Mature: 42083

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAQSLQHVKSSYIREILAAASDKNVISLAGGLPDEKTFPIDLMKPTLENLANMPEVFQ
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHH
YGSTAGYAPLLEFLNGYFKLPETHAAMITTGSQQGLDLIARAYVNPGDKVVMEAPSYLGA
CCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHHH
MQVFGLVQADIVTVSQTEFGPNLEELEQCFAEQKPKMFYAVPDFHNPTGVCWALETRQKV
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEHHHHHHH
AELCIQYNVAFIEDAPYRELRFSGEALPLVSDFCPQHSIVLRSFSKIASPGLRIGVVTGK
HHHHHHHCCEEECCCCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECC
SSYLEPLIKIKQGADLHSSVPMQALLHGLLQHDNFETHISTICELYKSRYDVMYAELEKQ
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSNCVLKPVDGGMFVWVEIPECDTFELAKSLLANGVAVVPSPVFYPEGSEVKAALRLNF
CCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEEEEE
TNATPEELKVAVTRLADVLNAL
CCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIAQSLQHVKSSYIREILAAASDKNVISLAGGLPDEKTFPIDLMKPTLENLANMPEVFQ
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHH
YGSTAGYAPLLEFLNGYFKLPETHAAMITTGSQQGLDLIARAYVNPGDKVVMEAPSYLGA
CCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHHH
MQVFGLVQADIVTVSQTEFGPNLEELEQCFAEQKPKMFYAVPDFHNPTGVCWALETRQKV
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEHHHHHHH
AELCIQYNVAFIEDAPYRELRFSGEALPLVSDFCPQHSIVLRSFSKIASPGLRIGVVTGK
HHHHHHHCCEEECCCCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECC
SSYLEPLIKIKQGADLHSSVPMQALLHGLLQHDNFETHISTICELYKSRYDVMYAELEKQ
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSNCVLKPVDGGMFVWVEIPECDTFELAKSLLANGVAVVPSPVFYPEGSEVKAALRLNF
CCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEEEEE
TNATPEELKVAVTRLADVLNAL
CCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA