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The map label for this gene is ptrB [C]

Identifier: 156977598

GI number: 156977598

Start: 1555088

End: 1557280

Strand: Reverse

Name: ptrB [C]

Synonym: VIBHAR_06386

Alternate gene names: 156977598

Gene position: 1557280-1555088 (Counterclockwise)

Preceding gene: 156977599

Following gene: 156977597

Centisome position: 70.66

GC content: 46.92

Gene sequence:

>2193_bases
ATGCATTACACAAAACAAAAACAGAAAAGGAAGTCTATGAAAAAGAAAACCTTAGCATTGGTCACGGCGTTTGCGATGAA
GGGAATGTTACCGAGTGCGTATGCAGAAGACTCAACACAAAAGTTGGTTGAACACGTACACAAAATGGCGGTGAAGTACC
CAACGACAAAGAAAGTCTCTGTGGAAGATGAGTATTTTGGTACCAAAGTTAGTGACCCGTACCGCTGGTTGGAGGACGAC
CGCAGCAAAGAAACCGCAGATTGGGTCAAAGCGCAGAACCAAGTCACGTTCGATTACTTGGCGCAAATTCCTTATCGTCA
CCAGATTGAAGAACGCTTAACTCAGTTGATGGATTACGAGAAGCTAGGGCGTCCATTCAAAGAAGGCAAATACACCTATT
TCTATAAGAACGACGGTTTGCAAAACCAAGATGTGCTTTACCGTCAACTCGATGATGGCAAGCCTGAAGTCTTCCTCGAC
CCAAATACTTTTAGTGAAGATGGCACAACTTCGCTGGCGAACGTGAGTTTCACCAAAGATGGTTCTTTAGTCGCTTACAG
CATTTCAGAAAGCGGTAGCGATTGGCGCAAAGTGATTGTGCTTGATGCCGAAACCAAAAAGCCTGTCGGTGAGACGCTGG
TGGATATTAAGTTCAGCAGCGTAAATTGGCTGGGTAATAAAGGTTTCTACTACTCAAGTTACGACAAGCCAGAGGGCAGC
GAACTTTCGGCAAAAACCGACCAACACAAGCTTTATTACCATGAGCTAGGCACTAAGCAGAGTGAAGACAAGCTTATCTT
CGGTGGTACAGATACTGAGAAGCACCGATATGTTCGCGGTTACACTTCCGATGACCAACGTTACCTGTTTATTTCGGCAA
ACACTTCAACGTCTGGCAATAAACTGTTCATGAAAGATTTGACCAAGCCAGACAGTCCGCTGCAAACCATTTTGGATGAC
ACCAATTCTGATACTTGGGTGATTGATAGCAAAGGCACTAAGCTGTATTTGGTCACTAACTTAGATGCGCCAAACAAACG
TGTAGTGACGGTGGATGCGAGTAACCCAGAGCCGAACAATTGGAAAGATCTAATCCCTGAAACTGACAACGTGCTTAGCC
CATCAACAGCGGGCGGTTACCTGTTCGCAAGCTACATTGTTGACGCGCTTTCGATGGTCAAACAATACGATATGGACGGT
AAGTTCATTCGTGAAATCAAGCTGCCAGACATCGGCAGTGCTTACGGTTTTTGGGGTAAGAAAGAAGACTCGGAAGTCTA
CTACTCTTTCACCAACTACAAGACGCCAAGCACGACCTATCGCTTAGACATCAAAGAGGGTGACAGCGAGGTTTACCACA
AATCGAACGCACCATTCGATCCGGCACAATTTGAATCTCGTCAGGTGTTCTACAAATCGAAAGATGGCACCAAGATTCCA
ATGATCATCACCTACAAAAAAGGCACGCCGATGGACGGCACTGCGCCAACGATCTTGTATGGTTATGGTGGTTTCAATAT
CAGCCTGACGCCTTACTTTAGTCCGAGTCGAGCAGCATGGTTGGAAATGGGCGGTATTTACGCTGTCGCGAACATCCGTG
GTGGTGGTGAGTACGGTAAAGAGTGGCACAATGCTGGCACCAAGTTAGAGAAACAAAACTCGTTTGATGACTTTATTGCC
GGAGCTGAGTTCCTTATCGATAAAGACTACACCTCATCAGACAAGCTTGCGATTAATGGTGGCTCGAACGGCGGCTTGCT
CGTCGGGGCAGTGATGACGCAGCGCCCAGAGCTGTTTAAAGTGGCACTGCCGGCAGTTGGTGTATTGGATATGCTTCGCT
ACCACACCTTTACGGCAGGAGCGGGCTGGGCTTATGACTATGGTACAGCAGAGCAAAGTAAAGAGATGTTCGATTACCTC
AAAGGTTACTCGCCAGTACACAACGTTAAAGCGGGTGTTAAGTACCCTGCAACTATGGTAACAACGGGAGACCACGATGA
CCGTGTGGTACCTGCACACTCGTACAAATTTGCGGCTGAGCTACAGTCTAAGCAAGCAGGCACGAACCCAACTTTGATTC
GAATCGAAACCAATGCAGGTCATGGTGCAGGCACACCGACTAGTAAGGTTATCGAGAAAACCGCGGATGTTTACAGCTTC
ACTTTGTTCAATATGGGCGTCGAAAAGCTGTAA

Upstream 100 bases:

>100_bases
CTGTCTATCTCATGGGGCAAAGTGACTCACTTTGTCTCCGTGGATTCACAGCTTTATTCAAACGACTAGAATCATTTCTC
CGATATAGGTAAGATGCTTG

Downstream 100 bases:

>100_bases
GTGAGAGGTTAGCTTACAGCTTGGACTTAAGTTCATTTTCAATGAATCACAACGCAGTCTTCGGGCTGCGTTTTTTATTT
TATCTCAGCCAGTTAATAAC

Product: peptidase

Products: NA

Alternate protein names: PE; Post-proline cleaving enzyme [H]

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MHYTKQKQKRKSMKKKTLALVTAFAMKGMLPSAYAEDSTQKLVEHVHKMAVKYPTTKKVSVEDEYFGTKVSDPYRWLEDD
RSKETADWVKAQNQVTFDYLAQIPYRHQIEERLTQLMDYEKLGRPFKEGKYTYFYKNDGLQNQDVLYRQLDDGKPEVFLD
PNTFSEDGTTSLANVSFTKDGSLVAYSISESGSDWRKVIVLDAETKKPVGETLVDIKFSSVNWLGNKGFYYSSYDKPEGS
ELSAKTDQHKLYYHELGTKQSEDKLIFGGTDTEKHRYVRGYTSDDQRYLFISANTSTSGNKLFMKDLTKPDSPLQTILDD
TNSDTWVIDSKGTKLYLVTNLDAPNKRVVTVDASNPEPNNWKDLIPETDNVLSPSTAGGYLFASYIVDALSMVKQYDMDG
KFIREIKLPDIGSAYGFWGKKEDSEVYYSFTNYKTPSTTYRLDIKEGDSEVYHKSNAPFDPAQFESRQVFYKSKDGTKIP
MIITYKKGTPMDGTAPTILYGYGGFNISLTPYFSPSRAAWLEMGGIYAVANIRGGGEYGKEWHNAGTKLEKQNSFDDFIA
GAEFLIDKDYTSSDKLAINGGSNGGLLVGAVMTQRPELFKVALPAVGVLDMLRYHTFTAGAGWAYDYGTAEQSKEMFDYL
KGYSPVHNVKAGVKYPATMVTTGDHDDRVVPAHSYKFAAELQSKQAGTNPTLIRIETNAGHGAGTPTSKVIEKTADVYSF
TLFNMGVEKL

Sequences:

>Translated_730_residues
MHYTKQKQKRKSMKKKTLALVTAFAMKGMLPSAYAEDSTQKLVEHVHKMAVKYPTTKKVSVEDEYFGTKVSDPYRWLEDD
RSKETADWVKAQNQVTFDYLAQIPYRHQIEERLTQLMDYEKLGRPFKEGKYTYFYKNDGLQNQDVLYRQLDDGKPEVFLD
PNTFSEDGTTSLANVSFTKDGSLVAYSISESGSDWRKVIVLDAETKKPVGETLVDIKFSSVNWLGNKGFYYSSYDKPEGS
ELSAKTDQHKLYYHELGTKQSEDKLIFGGTDTEKHRYVRGYTSDDQRYLFISANTSTSGNKLFMKDLTKPDSPLQTILDD
TNSDTWVIDSKGTKLYLVTNLDAPNKRVVTVDASNPEPNNWKDLIPETDNVLSPSTAGGYLFASYIVDALSMVKQYDMDG
KFIREIKLPDIGSAYGFWGKKEDSEVYYSFTNYKTPSTTYRLDIKEGDSEVYHKSNAPFDPAQFESRQVFYKSKDGTKIP
MIITYKKGTPMDGTAPTILYGYGGFNISLTPYFSPSRAAWLEMGGIYAVANIRGGGEYGKEWHNAGTKLEKQNSFDDFIA
GAEFLIDKDYTSSDKLAINGGSNGGLLVGAVMTQRPELFKVALPAVGVLDMLRYHTFTAGAGWAYDYGTAEQSKEMFDYL
KGYSPVHNVKAGVKYPATMVTTGDHDDRVVPAHSYKFAAELQSKQAGTNPTLIRIETNAGHGAGTPTSKVIEKTADVYSF
TLFNMGVEKL
>Mature_730_residues
MHYTKQKQKRKSMKKKTLALVTAFAMKGMLPSAYAEDSTQKLVEHVHKMAVKYPTTKKVSVEDEYFGTKVSDPYRWLEDD
RSKETADWVKAQNQVTFDYLAQIPYRHQIEERLTQLMDYEKLGRPFKEGKYTYFYKNDGLQNQDVLYRQLDDGKPEVFLD
PNTFSEDGTTSLANVSFTKDGSLVAYSISESGSDWRKVIVLDAETKKPVGETLVDIKFSSVNWLGNKGFYYSSYDKPEGS
ELSAKTDQHKLYYHELGTKQSEDKLIFGGTDTEKHRYVRGYTSDDQRYLFISANTSTSGNKLFMKDLTKPDSPLQTILDD
TNSDTWVIDSKGTKLYLVTNLDAPNKRVVTVDASNPEPNNWKDLIPETDNVLSPSTAGGYLFASYIVDALSMVKQYDMDG
KFIREIKLPDIGSAYGFWGKKEDSEVYYSFTNYKTPSTTYRLDIKEGDSEVYHKSNAPFDPAQFESRQVFYKSKDGTKIP
MIITYKKGTPMDGTAPTILYGYGGFNISLTPYFSPSRAAWLEMGGIYAVANIRGGGEYGKEWHNAGTKLEKQNSFDDFIA
GAEFLIDKDYTSSDKLAINGGSNGGLLVGAVMTQRPELFKVALPAVGVLDMLRYHTFTAGAGWAYDYGTAEQSKEMFDYL
KGYSPVHNVKAGVKYPATMVTTGDHDDRVVPAHSYKFAAELQSKQAGTNPTLIRIETNAGHGAGTPTSKVIEKTADVYSF
TLFNMGVEKL

Specific function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Has an absolute requirement for an X-Pro bond in the trans configuration immediately preceding the Pro-Y scissible bond [H]

COG id: COG1505

COG function: function code E; Serine proteases of the peptidase family S9A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=712, Percent_Identity=42.5561797752809, Blast_Score=545, Evalue=1e-155,
Organism=Homo sapiens, GI284172420, Length=433, Percent_Identity=23.5565819861432, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI284172413, Length=433, Percent_Identity=23.5565819861432, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI70778815, Length=433, Percent_Identity=23.5565819861432, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI284172438, Length=433, Percent_Identity=23.5565819861432, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI284172431, Length=433, Percent_Identity=23.5565819861432, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI108860686, Length=272, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI108860692, Length=199, Percent_Identity=28.1407035175879, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1788150, Length=674, Percent_Identity=25.3709198813056, Blast_Score=204, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24583414, Length=711, Percent_Identity=41.7721518987342, Blast_Score=524, Evalue=1e-148,
Organism=Drosophila melanogaster, GI221510989, Length=703, Percent_Identity=40.398293029872, Blast_Score=492, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.26 [H]

Molecular weight: Translated: 82005; Mature: 82005

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYTKQKQKRKSMKKKTLALVTAFAMKGMLPSAYAEDSTQKLVEHVHKMAVKYPTTKKVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEE
VEDEYFGTKVSDPYRWLEDDRSKETADWVKAQNQVTFDYLAQIPYRHQIEERLTQLMDYE
ECHHHCCCCCCCCHHHHHCCCCCHHHHHHHHCCCEEHHHHHCCCCHHHHHHHHHHHHCHH
KLGRPFKEGKYTYFYKNDGLQNQDVLYRQLDDGKPEVFLDPNTFSEDGTTSLANVSFTKD
HHCCCHHCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEEECC
GSLVAYSISESGSDWRKVIVLDAETKKPVGETLVDIKFSSVNWLGNKGFYYSSYDKPEGS
CCEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEEECEEEECCCCCEECCCCCCCCC
ELSAKTDQHKLYYHELGTKQSEDKLIFGGTDTEKHRYVRGYTSDDQRYLFISANTSTSGN
CCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCEEEECCCCCCCEEEEEEECCCCCCC
KLFMKDLTKPDSPLQTILDDTNSDTWVIDSKGTKLYLVTNLDAPNKRVVTVDASNPEPNN
EEEEECCCCCCCHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCCC
WKDLIPETDNVLSPSTAGGYLFASYIVDALSMVKQYDMDGKFIREIKLPDIGSAYGFWGK
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
KEDSEVYYSFTNYKTPSTTYRLDIKEGDSEVYHKSNAPFDPAQFESRQVFYKSKDGTKIP
CCCCEEEEEEECCCCCCCEEEEEEECCCCHHEECCCCCCCCHHCCCCEEEEECCCCCCCC
MIITYKKGTPMDGTAPTILYGYGGFNISLTPYFSPSRAAWLEMGGIYAVANIRGGGEYGK
EEEEECCCCCCCCCCCEEEEEECCEEEEEECCCCCCCHHHEECCCEEEEEEECCCCHHHH
EWHNAGTKLEKQNSFDDFIAGAEFLIDKDYTSSDKLAINGGSNGGLLVGAVMTQRPELFK
HHHHCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCEEEECCCCCCEEEEEEHHCCCCCEE
VALPAVGVLDMLRYHTFTAGAGWAYDYGTAEQSKEMFDYLKGYSPVHNVKAGVKYPATMV
EHHHHHHHHHHHHHHEEECCCCCEECCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEE
TTGDHDDRVVPAHSYKFAAELQSKQAGTNPTLIRIETNAGHGAGTPTSKVIEKTADVYSF
ECCCCCCEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHEE
TLFNMGVEKL
EEHHCCHHCC
>Mature Secondary Structure
MHYTKQKQKRKSMKKKTLALVTAFAMKGMLPSAYAEDSTQKLVEHVHKMAVKYPTTKKVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEE
VEDEYFGTKVSDPYRWLEDDRSKETADWVKAQNQVTFDYLAQIPYRHQIEERLTQLMDYE
ECHHHCCCCCCCCHHHHHCCCCCHHHHHHHHCCCEEHHHHHCCCCHHHHHHHHHHHHCHH
KLGRPFKEGKYTYFYKNDGLQNQDVLYRQLDDGKPEVFLDPNTFSEDGTTSLANVSFTKD
HHCCCHHCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEEECC
GSLVAYSISESGSDWRKVIVLDAETKKPVGETLVDIKFSSVNWLGNKGFYYSSYDKPEGS
CCEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEEECEEEECCCCCEECCCCCCCCC
ELSAKTDQHKLYYHELGTKQSEDKLIFGGTDTEKHRYVRGYTSDDQRYLFISANTSTSGN
CCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCEEEECCCCCCCEEEEEEECCCCCCC
KLFMKDLTKPDSPLQTILDDTNSDTWVIDSKGTKLYLVTNLDAPNKRVVTVDASNPEPNN
EEEEECCCCCCCHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCCC
WKDLIPETDNVLSPSTAGGYLFASYIVDALSMVKQYDMDGKFIREIKLPDIGSAYGFWGK
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
KEDSEVYYSFTNYKTPSTTYRLDIKEGDSEVYHKSNAPFDPAQFESRQVFYKSKDGTKIP
CCCCEEEEEEECCCCCCCEEEEEEECCCCHHEECCCCCCCCHHCCCCEEEEECCCCCCCC
MIITYKKGTPMDGTAPTILYGYGGFNISLTPYFSPSRAAWLEMGGIYAVANIRGGGEYGK
EEEEECCCCCCCCCCCEEEEEECCEEEEEECCCCCCCHHHEECCCEEEEEEECCCCHHHH
EWHNAGTKLEKQNSFDDFIAGAEFLIDKDYTSSDKLAINGGSNGGLLVGAVMTQRPELFK
HHHHCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCEEEECCCCCCEEEEEEHHCCCCCEE
VALPAVGVLDMLRYHTFTAGAGWAYDYGTAEQSKEMFDYLKGYSPVHNVKAGVKYPATMV
EHHHHHHHHHHHHHHEEECCCCCEECCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEE
TTGDHDDRVVPAHSYKFAAELQSKQAGTNPTLIRIETNAGHGAGTPTSKVIEKTADVYSF
ECCCCCCEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHEE
TLFNMGVEKL
EEHHCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8370677 [H]