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The map label for this gene is ctaC [H]

Identifier: 156977485

GI number: 156977485

Start: 1453587

End: 1454804

Strand: Reverse

Name: ctaC [H]

Synonym: VIBHAR_06272

Alternate gene names: 156977485

Gene position: 1454804-1453587 (Counterclockwise)

Preceding gene: 156977490

Following gene: 156977484

Centisome position: 66.01

GC content: 47.95

Gene sequence:

>1218_bases
TTGGGAAGCAAGGAAGCTGGCGCAAGCGCAGCGGCTGAGCAGAGGAGAGATCTTTTGAAAAGATTAGCAACTACTCTAGC
CTTATTAACGAATGTGATTTTTATCACATTTTCTTCGTCAAGTTGGTCAGAGCAAAATGATTACAACATGACGCGGGGTG
TTACGGGGATCAGTGAGCAAGTGTATGAATTACATATGCTGATCTTCTATATATGCTGCGCCATTGCCTTTGTTGTATTT
GGCGTGATGTTCTATTCCATCTTCCGACACCGCAAGTCAAAAGGGGCAGTTGCGGCTAATTTCCACGAAAGCACCAAAGT
GGAGGTTATCTGGACCGTCATCCCAGTCATTATCCTTATCGCGATGGCGATTCCAGCAACCAAAACACTGGTGGCAATGG
AAGATACTAGCCAATCTGACCTCACCATTAAGATCACAGGCTCTCAATGGAAGTGGCATTACAGCTACTTCGGCGAGGAT
GTCGAATTTTTTAGTCTGCTCGCAACCAGTCAAAAAGAAATTGATGGCATTGAAGCAAAAGGGGCGCACTACTTACTTGA
AGTGGATAATCCGCTCGTTCTGCCTATCAATCGTAAAGTTCGCTTCTTAATGACCTCAGATGACGTGATTCATTCATGGT
GGGTGCCTGACTTCGCGGTTAAGAAAGACACCATCCCGGGGTTTATCAATGAAGCGTGGACCAAGATTGATGAGCCGGGC
GTCTATCGCGGTCAGTGTGCCGAGCTTTGTGGTCGAGCGCATGGTTTTATGCCAGTAGTTGTTCATGCAATGGCAGAAGA
CGACTTTGACCAGTGGATGTCAGACAAGAAGCAAGAGCTTGCTTTACAAAAAGCGGCCGCACAAGAGGCGTTGACGCAAG
ATCTGTCGATGGAAGATTTGATGGGGCAAGGCGAGTCGATTTACACCGCGCGTTGTGCCGTGTGCCATCAAGCAAATGGT
GAAGGCATCCCGGGCGCATTCCCGGCGATCAAAGGCAGCGAAATAGCTAAAGGTCCGGTTATGGCTCACATCGATGTACT
AGTAAACGGTCGTGCAGGGACAGCGATGCAAGCTTTTGCCAACCAACTTAGCGACCAGGAAATTGCTGCTGTTATTACCT
ATCAACGAAATGCTTGGGGAAATGACACTGGCGACACCGTTCAAGCATCCGATGTTAACGCCTTTAAGGCACAAGACAGT
GCCAAGGAGGAAATATGA

Upstream 100 bases:

>100_bases
AAGAACTATTGAACTATAACTAGCCTTTTAACATAAATATAACAAAGAGTGCTGAAATCGTAGTTTTTATGATTTTTTGT
AAATTTGTTCGATATTTGCA

Downstream 100 bases:

>100_bases
GTAAGCCAATTGAAAAAGCGGTGAAATCTGCTCCTGCAGAAGCTCAAACGACCGCAAATACTACCATTGCGATTGAAGAC
GATCACGACCATCATCACGC

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MGSKEAGASAAAEQRRDLLKRLATTLALLTNVIFITFSSSSWSEQNDYNMTRGVTGISEQVYELHMLIFYICCAIAFVVF
GVMFYSIFRHRKSKGAVAANFHESTKVEVIWTVIPVIILIAMAIPATKTLVAMEDTSQSDLTIKITGSQWKWHYSYFGED
VEFFSLLATSQKEIDGIEAKGAHYLLEVDNPLVLPINRKVRFLMTSDDVIHSWWVPDFAVKKDTIPGFINEAWTKIDEPG
VYRGQCAELCGRAHGFMPVVVHAMAEDDFDQWMSDKKQELALQKAAAQEALTQDLSMEDLMGQGESIYTARCAVCHQANG
EGIPGAFPAIKGSEIAKGPVMAHIDVLVNGRAGTAMQAFANQLSDQEIAAVITYQRNAWGNDTGDTVQASDVNAFKAQDS
AKEEI

Sequences:

>Translated_405_residues
MGSKEAGASAAAEQRRDLLKRLATTLALLTNVIFITFSSSSWSEQNDYNMTRGVTGISEQVYELHMLIFYICCAIAFVVF
GVMFYSIFRHRKSKGAVAANFHESTKVEVIWTVIPVIILIAMAIPATKTLVAMEDTSQSDLTIKITGSQWKWHYSYFGED
VEFFSLLATSQKEIDGIEAKGAHYLLEVDNPLVLPINRKVRFLMTSDDVIHSWWVPDFAVKKDTIPGFINEAWTKIDEPG
VYRGQCAELCGRAHGFMPVVVHAMAEDDFDQWMSDKKQELALQKAAAQEALTQDLSMEDLMGQGESIYTARCAVCHQANG
EGIPGAFPAIKGSEIAKGPVMAHIDVLVNGRAGTAMQAFANQLSDQEIAAVITYQRNAWGNDTGDTVQASDVNAFKAQDS
AKEEI
>Mature_404_residues
GSKEAGASAAAEQRRDLLKRLATTLALLTNVIFITFSSSSWSEQNDYNMTRGVTGISEQVYELHMLIFYICCAIAFVVFG
VMFYSIFRHRKSKGAVAANFHESTKVEVIWTVIPVIILIAMAIPATKTLVAMEDTSQSDLTIKITGSQWKWHYSYFGEDV
EFFSLLATSQKEIDGIEAKGAHYLLEVDNPLVLPINRKVRFLMTSDDVIHSWWVPDFAVKKDTIPGFINEAWTKIDEPGV
YRGQCAELCGRAHGFMPVVVHAMAEDDFDQWMSDKKQELALQKAAAQEALTQDLSMEDLMGQGESIYTARCAVCHQANGE
GIPGAFPAIKGSEIAKGPVMAHIDVLVNGRAGTAMQAFANQLSDQEIAAVITYQRNAWGNDTGDTVQASDVNAFKAQDSA
KEEI

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=33.0316742081448, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI1786635, Length=236, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6226540, Length=227, Percent_Identity=33.4801762114537, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR005728 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 44700; Mature: 44569

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSKEAGASAAAEQRRDLLKRLATTLALLTNVIFITFSSSSWSEQNDYNMTRGVTGISEQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHCCCHHHHH
VYELHMLIFYICCAIAFVVFGVMFYSIFRHRKSKGAVAANFHESTKVEVIWTVIPVIILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AMAIPATKTLVAMEDTSQSDLTIKITGSQWKWHYSYFGEDVEFFSLLATSQKEIDGIEAK
HHHCCCCCEEEEEECCCCCCEEEEEECCCEEEEHHHHCCCHHHHHHHHHCHHHHCCCCCC
GAHYLLEVDNPLVLPINRKVRFLMTSDDVIHSWWVPDFAVKKDTIPGFINEAWTKIDEPG
CCEEEEEECCCEEEECCCCEEEEEECCCHHHCCCCCCHHCCCCCCCHHHHHHHHCCCCCC
VYRGQCAELCGRAHGFMPVVVHAMAEDDFDQWMSDKKQELALQKAAAQEALTQDLSMEDL
CCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MGQGESIYTARCAVCHQANGEGIPGAFPAIKGSEIAKGPVMAHIDVLVNGRAGTAMQAFA
HCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHH
NQLSDQEIAAVITYQRNAWGNDTGDTVQASDVNAFKAQDSAKEEI
HHCCCCCEEEEEEEECCCCCCCCCCEEEECCCCHHHCCCCHHCCC
>Mature Secondary Structure 
GSKEAGASAAAEQRRDLLKRLATTLALLTNVIFITFSSSSWSEQNDYNMTRGVTGISEQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHCCCHHHHH
VYELHMLIFYICCAIAFVVFGVMFYSIFRHRKSKGAVAANFHESTKVEVIWTVIPVIILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AMAIPATKTLVAMEDTSQSDLTIKITGSQWKWHYSYFGEDVEFFSLLATSQKEIDGIEAK
HHHCCCCCEEEEEECCCCCCEEEEEECCCEEEEHHHHCCCHHHHHHHHHCHHHHCCCCCC
GAHYLLEVDNPLVLPINRKVRFLMTSDDVIHSWWVPDFAVKKDTIPGFINEAWTKIDEPG
CCEEEEEECCCEEEECCCCEEEEEECCCHHHCCCCCCHHCCCCCCCHHHHHHHHCCCCCC
VYRGQCAELCGRAHGFMPVVVHAMAEDDFDQWMSDKKQELALQKAAAQEALTQDLSMEDL
CCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MGQGESIYTARCAVCHQANGEGIPGAFPAIKGSEIAKGPVMAHIDVLVNGRAGTAMQAFA
HCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHH
NQLSDQEIAAVITYQRNAWGNDTGDTVQASDVNAFKAQDSAKEEI
HHCCCCCEEEEEEEECCCCCCCCCCEEEECCCCHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]