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The map label for this gene is ctaD [H]

Identifier: 156977484

GI number: 156977484

Start: 1451950

End: 1453590

Strand: Reverse

Name: ctaD [H]

Synonym: VIBHAR_06271

Alternate gene names: 156977484

Gene position: 1453590-1451950 (Counterclockwise)

Preceding gene: 156977485

Following gene: 156977483

Centisome position: 65.95

GC content: 49.12

Gene sequence:

>1641_bases
ATGAGTAAGCCAATTGAAAAAGCGGTGAAATCTGCTCCTGCAGAAGCTCAAACGACCGCAAATACTACCATTGCGATTGA
AGACGATCACGACCATCATCACGCGCCGAAAGGGCTAACGCGTTGGCTCTACTCCACCAGCCATAAAGACATAGGTACGC
TTTACTTGTGGTTTAGTTTTGCCATGTTCCTTACTGGCGGAGCAATGGCGATGATCATTCGCGCAGAGCTATTCCAACCG
GGTTTGCAATTGGTTGATCCTCAGTTCTTTAACCAGATGACGACCGTGCATGGGCTAGTAATGGTATTTGGTGCCGTCAT
GCCTGCGTTTACTGGCTTAGCCAACTGGATGATTCCAATGATGATTGGCGCTCCGGACATGGCTTTGCCACGAATGAACA
ACTTGAGCTTTTGGATCTTACCTTTTGCTTTCCTCATTTTGATCGGCTCTTTGTTCTTACCGGGTGGGGGGCCTGATTTC
GGGTGGACTTTCTACGCGCCACTTTCTACAACCTACGGCCCTGACAGTACGGCGTTGTTTGTTTTCTCAGTCCATATCAT
GGGTATCAGTTCCATCATGGGTGCCATCAACGTCATCGTGACGATTGTAAATATGCGTGCACCGGGCATGACTTGGTTCA
AGCTACCTATGTTCGTCTGGACTTGGCTAATCACGGCGTTCTTGCTGATAGCTGTGATGCCCGTATTAGCCGGTGCGGTG
ACCATGGTTTTGACCGACAAATACTTCGGTACCAGCTTCTTTGATGCCGCTGGTGGCGGTGACCCGGTGATGTTCCAACA
CATTTTCTGGTTCTTTGGTCACCCAGAGGTGTACATCATGATCTTGCCTTCGTTTGGTATTGTCTCGGCAATCATTCCGG
CGTTTAGCGGTAAGAAGTTGTTCGGTTACCATTCAATGGTTTACGCGACTTGTAGTATTGCGTTGCTTTCATTCCTCGTC
TGGGCACACCATATGTTTACCACGGGGATGCCGGTATTCGCCGAACTCTTCTTTATGTACTGCACCATGTTGATTGCAGT
ACCCACGGGGGTGAAGGTATTTAATTGGGTGGCGACCATGTGGCGCGGAGCCATGACGTTTGAGACGCCGATGTTATTTG
CTATCGCCTTTATTGTCCTATTCACGATAGGTGGTTTCTCCGGCTTGATGTTGGCCATTGTGCCAGCAGACTTCCAATAC
CACGACACGTACTTTGTTGTCGCTCACTTCCATTATGTCTTGGTCTCCGGTGCGGTGTTCTCGATTATGGCAGCGGCGTA
TTACTGGCTACCGAAGTGGACGGGCAATATGTACGACCAAAAGCTCAGTCTGTGGCATTTCTGGTGCTCCATCATCTCGG
TCAACGTCTTGTTCTTCCCAATGCACTTCTTGGGTTTAGCGGGGATGCCAAGACGTATTCCTGATTACGCCATCCAGTTT
GCGGATATTAACCAAATCGTATCGATAGGTGGTTTCGCCTTTGGCTTGTCTCAACTGATCTTCTTGTGGTTGGTGATCAA
ATGTATCCGTGGTGGTGAAAAAGCAACAGCCAAACCGTGGGAACGTGCAGAAGGTTTAGAGTGGACGGTGCCAAGTCCTG
CTCCGCATCATACGTTCACAACACCGCCAAAAGTTGATTAA

Upstream 100 bases:

>100_bases
TTACCTATCAACGAAATGCTTGGGGAAATGACACTGGCGACACCGTTCAAGCATCCGATGTTAACGCCTTTAAGGCACAA
GACAGTGCCAAGGAGGAAAT

Downstream 100 bases:

>100_bases
GAAAGCGTGAGGTGAGTGAGATGCAAAGTAATTCATCCAATAAAAAACTCACTATCAAGTTGCTGTTAGCGACTGCGCTG
ATGTTCGGCTTCGGTTTTGC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSKPIEKAVKSAPAEAQTTANTTIAIEDDHDHHHAPKGLTRWLYSTSHKDIGTLYLWFSFAMFLTGGAMAMIIRAELFQP
GLQLVDPQFFNQMTTVHGLVMVFGAVMPAFTGLANWMIPMMIGAPDMALPRMNNLSFWILPFAFLILIGSLFLPGGGPDF
GWTFYAPLSTTYGPDSTALFVFSVHIMGISSIMGAINVIVTIVNMRAPGMTWFKLPMFVWTWLITAFLLIAVMPVLAGAV
TMVLTDKYFGTSFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIVSAIIPAFSGKKLFGYHSMVYATCSIALLSFLV
WAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGAMTFETPMLFAIAFIVLFTIGGFSGLMLAIVPADFQY
HDTYFVVAHFHYVLVSGAVFSIMAAAYYWLPKWTGNMYDQKLSLWHFWCSIISVNVLFFPMHFLGLAGMPRRIPDYAIQF
ADINQIVSIGGFAFGLSQLIFLWLVIKCIRGGEKATAKPWERAEGLEWTVPSPAPHHTFTTPPKVD

Sequences:

>Translated_546_residues
MSKPIEKAVKSAPAEAQTTANTTIAIEDDHDHHHAPKGLTRWLYSTSHKDIGTLYLWFSFAMFLTGGAMAMIIRAELFQP
GLQLVDPQFFNQMTTVHGLVMVFGAVMPAFTGLANWMIPMMIGAPDMALPRMNNLSFWILPFAFLILIGSLFLPGGGPDF
GWTFYAPLSTTYGPDSTALFVFSVHIMGISSIMGAINVIVTIVNMRAPGMTWFKLPMFVWTWLITAFLLIAVMPVLAGAV
TMVLTDKYFGTSFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIVSAIIPAFSGKKLFGYHSMVYATCSIALLSFLV
WAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGAMTFETPMLFAIAFIVLFTIGGFSGLMLAIVPADFQY
HDTYFVVAHFHYVLVSGAVFSIMAAAYYWLPKWTGNMYDQKLSLWHFWCSIISVNVLFFPMHFLGLAGMPRRIPDYAIQF
ADINQIVSIGGFAFGLSQLIFLWLVIKCIRGGEKATAKPWERAEGLEWTVPSPAPHHTFTTPPKVD
>Mature_545_residues
SKPIEKAVKSAPAEAQTTANTTIAIEDDHDHHHAPKGLTRWLYSTSHKDIGTLYLWFSFAMFLTGGAMAMIIRAELFQPG
LQLVDPQFFNQMTTVHGLVMVFGAVMPAFTGLANWMIPMMIGAPDMALPRMNNLSFWILPFAFLILIGSLFLPGGGPDFG
WTFYAPLSTTYGPDSTALFVFSVHIMGISSIMGAINVIVTIVNMRAPGMTWFKLPMFVWTWLITAFLLIAVMPVLAGAVT
MVLTDKYFGTSFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIVSAIIPAFSGKKLFGYHSMVYATCSIALLSFLVW
AHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGAMTFETPMLFAIAFIVLFTIGGFSGLMLAIVPADFQYH
DTYFVVAHFHYVLVSGAVFSIMAAAYYWLPKWTGNMYDQKLSLWHFWCSIISVNVLFFPMHFLGLAGMPRRIPDYAIQFA
DINQIVSIGGFAFGLSQLIFLWLVIKCIRGGEKATAKPWERAEGLEWTVPSPAPHHTFTTPPKVD

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=506, Percent_Identity=49.604743083004, Blast_Score=449, Evalue=1e-126,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=40.0778210116732, Blast_Score=349, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=46.5160075329567, Blast_Score=465, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=49.2307692307692, Blast_Score=311, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6226523, Length=250, Percent_Identity=46, Blast_Score=205, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60895; Mature: 60764

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIEKAVKSAPAEAQTTANTTIAIEDDHDHHHAPKGLTRWLYSTSHKDIGTLYLWFSF
CCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
AMFLTGGAMAMIIRAELFQPGLQLVDPQFFNQMTTVHGLVMVFGAVMPAFTGLANWMIPM
HHHHHCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIGAPDMALPRMNNLSFWILPFAFLILIGSLFLPGGGPDFGWTFYAPLSTTYGPDSTALF
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEE
VFSVHIMGISSIMGAINVIVTIVNMRAPGMTWFKLPMFVWTWLITAFLLIAVMPVLAGAV
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMVLTDKYFGTSFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIVSAIIPAFSGKKL
HHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCH
FGYHSMVYATCSIALLSFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
WRGAMTFETPMLFAIAFIVLFTIGGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVSGAVF
HCCCCCCCHHHHHHHHHHHHHHHCCHHHHEEEEEECCCEECCCEEHHHHHHHHHHHHHHH
SIMAAAYYWLPKWTGNMYDQKLSLWHFWCSIISVNVLFFPMHFLGLAGMPRRIPDYAIQF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEH
ADINQIVSIGGFAFGLSQLIFLWLVIKCIRGGEKATAKPWERAEGLEWTVPSPAPHHTFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEECCCCCCCCCCC
TPPKVD
CCCCCC
>Mature Secondary Structure 
SKPIEKAVKSAPAEAQTTANTTIAIEDDHDHHHAPKGLTRWLYSTSHKDIGTLYLWFSF
CCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
AMFLTGGAMAMIIRAELFQPGLQLVDPQFFNQMTTVHGLVMVFGAVMPAFTGLANWMIPM
HHHHHCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIGAPDMALPRMNNLSFWILPFAFLILIGSLFLPGGGPDFGWTFYAPLSTTYGPDSTALF
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEE
VFSVHIMGISSIMGAINVIVTIVNMRAPGMTWFKLPMFVWTWLITAFLLIAVMPVLAGAV
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMVLTDKYFGTSFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIVSAIIPAFSGKKL
HHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCH
FGYHSMVYATCSIALLSFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
WRGAMTFETPMLFAIAFIVLFTIGGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVSGAVF
HCCCCCCCHHHHHHHHHHHHHHHCCHHHHEEEEEECCCEECCCEEHHHHHHHHHHHHHHH
SIMAAAYYWLPKWTGNMYDQKLSLWHFWCSIISVNVLFFPMHFLGLAGMPRRIPDYAIQF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEH
ADINQIVSIGGFAFGLSQLIFLWLVIKCIRGGEKATAKPWERAEGLEWTVPSPAPHHTFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEECCCCCCCCCCC
TPPKVD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]