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The map label for this gene is ribB [H]

Identifier: 156977451

GI number: 156977451

Start: 1419098

End: 1419790

Strand: Reverse

Name: ribB [H]

Synonym: VIBHAR_06238

Alternate gene names: 156977451

Gene position: 1419790-1419098 (Counterclockwise)

Preceding gene: 156977452

Following gene: 156977448

Centisome position: 64.42

GC content: 46.75

Gene sequence:

>693_bases
ATGAGCTCAACGTCACTACTAGATGAGTTTGGCACTCCAGTACAAAGGGTAGAAAGAGCGATTGAGGCTCTGAAAAATGG
CCTTGGTGTTCTATTAATGGATGATGAGGATCGCGAGAACGAAGGCGACCTTATCTTCTCTGCACAGCATCTTACCGAAG
CGCAAATGGCACTCATGATTCGTGAATGCAGTGGCATCGTGTGTTTGTGCTTAACGGAGGAACGCGCCAATTGGTTAGAG
CTTCCTCCTATGGTGAAAGATAATCGCAGTAAAAACCAGACCGCTTTTACGGTTTCGATTGAAGCGAAAGAAGGGGTGAC
GACAGGGGTCTCTGCGAAAGATCGCGTTACAACGGTCAAAACGGCCACTTATTTTGATGCTCAACCAGAAGATTTAGCAA
GACCAGGCCATGTTTTTCCACTGGTTGCGAAAACAAATGGCGTGTTGGCCCGTCGAGGTCATACCGAAGGTACGATCGAT
TTGATGTATCTAGCAAACTTAGTCCCGTCAGGGATCCTTTGTGAACTGACTAACCGTGATGGAACCATGGCGAAACTGCC
AGAGACCATTGAATTTGCAAGGCGTCATGGAATGCCAGTACTCACTATTGAAGATATCGTCGATTATCGAACGGGTATCG
ACCTGAGAAATGAATATGAGAGTGGCTTAGTGTGTGAAGTGAGTTGGTCTTAG

Upstream 100 bases:

>100_bases
GTGGCTCGTGATTGGTTCTGTGACAAAAGAGGGGCAGAACCAGAGCAAATTTACGCGGACGCGTTCGCTTATTTGTAATC
ATTATCAAGGAGAAGAAACT

Downstream 100 bases:

>100_bases
TATTTAAAGTTCCTTTGTTTGTTCAGTCGCCTAGCTGACTTTCCGCCCTTATCGGGCGGTTTTTTGTTTTGCAGAAGTCA
AAAATAAACCCGCAAAAGCG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase; LUXH protein [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSSTSLLDEFGTPVQRVERAIEALKNGLGVLLMDDEDRENEGDLIFSAQHLTEAQMALMIRECSGIVCLCLTEERANWLE
LPPMVKDNRSKNQTAFTVSIEAKEGVTTGVSAKDRVTTVKTATYFDAQPEDLARPGHVFPLVAKTNGVLARRGHTEGTID
LMYLANLVPSGILCELTNRDGTMAKLPETIEFARRHGMPVLTIEDIVDYRTGIDLRNEYESGLVCEVSWS

Sequences:

>Translated_230_residues
MSSTSLLDEFGTPVQRVERAIEALKNGLGVLLMDDEDRENEGDLIFSAQHLTEAQMALMIRECSGIVCLCLTEERANWLE
LPPMVKDNRSKNQTAFTVSIEAKEGVTTGVSAKDRVTTVKTATYFDAQPEDLARPGHVFPLVAKTNGVLARRGHTEGTID
LMYLANLVPSGILCELTNRDGTMAKLPETIEFARRHGMPVLTIEDIVDYRTGIDLRNEYESGLVCEVSWS
>Mature_229_residues
SSTSLLDEFGTPVQRVERAIEALKNGLGVLLMDDEDRENEGDLIFSAQHLTEAQMALMIRECSGIVCLCLTEERANWLEL
PPMVKDNRSKNQTAFTVSIEAKEGVTTGVSAKDRVTTVKTATYFDAQPEDLARPGHVFPLVAKTNGVLARRGHTEGTIDL
MYLANLVPSGILCELTNRDGTMAKLPETIEFARRHGMPVLTIEDIVDYRTGIDLRNEYESGLVCEVSWS

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=206, Percent_Identity=63.1067961165049, Blast_Score=268, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=38.8059701492537, Blast_Score=158, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 25448; Mature: 25317

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSLLDEFGTPVQRVERAIEALKNGLGVLLMDDEDRENEGDLIFSAQHLTEAQMALMI
CCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHH
RECSGIVCLCLTEERANWLELPPMVKDNRSKNQTAFTVSIEAKEGVTTGVSAKDRVTTVK
HHCCCEEEEEEECCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEE
TATYFDAQPEDLARPGHVFPLVAKTNGVLARRGHTEGTIDLMYLANLVPSGILCELTNRD
EEEEECCCHHHHCCCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCC
GTMAKLPETIEFARRHGMPVLTIEDIVDYRTGIDLRNEYESGLVCEVSWS
CCHHHCHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHCCCCEEEEEECC
>Mature Secondary Structure 
SSTSLLDEFGTPVQRVERAIEALKNGLGVLLMDDEDRENEGDLIFSAQHLTEAQMALMI
CCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHH
RECSGIVCLCLTEERANWLELPPMVKDNRSKNQTAFTVSIEAKEGVTTGVSAKDRVTTVK
HHCCCEEEEEEECCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEE
TATYFDAQPEDLARPGHVFPLVAKTNGVLARRGHTEGTIDLMYLANLVPSGILCELTNRD
EEEEECCCHHHHCCCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCC
GTMAKLPETIEFARRHGMPVLTIEDIVDYRTGIDLRNEYESGLVCEVSWS
CCHHHCHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2303459 [H]