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The map label for this gene is rbsK [H]

Identifier: 156977356

GI number: 156977356

Start: 1320238

End: 1321155

Strand: Reverse

Name: rbsK [H]

Synonym: VIBHAR_06142

Alternate gene names: 156977356

Gene position: 1321155-1320238 (Counterclockwise)

Preceding gene: 156977357

Following gene: 156977355

Centisome position: 59.94

GC content: 48.69

Gene sequence:

>918_bases
ATGAATAAGTTAGTGGTGTTAGGTAGTGTAAACGCTGACCATGTTCTTCAAGTGCCTTCTTTCCCTCGCCCTGGCGAGAC
GCTGCATGGTCGCAACTATCAAGTTATCCCAGGTGGCAAGGGTGCCAACCAAGCTGTGGCGGCAGCTCGATTAAACGCAG
ACATCGGTTTTATTGCGTGTGTTGGTGATGATTCGTTCGGCATCAACATTCGTGAGAACTTCAAAATGGATGGCATCGAT
ATCACTGGTGTAAAGATGCAGCCAAACTGCCCAACAGGCATTGCCATGATTCAGGTGGCGGACAGTGGTGAGAACAGTAT
TTGTATCTCCGCAGAAGCGAACGCAAAACTTACCGCAGAAGCGATTGAGCCCGACCTAGAGCGCATTCGTCAGGCAGATT
ACTTATTGATGCAACTAGAAACGCCAATGTGCGGTATCGAGAAAGCAGCGCGAATCGCGAAAGATGCCAAAACCAACGTG
ATTCTAAACCCAGCACCAGCTCGCGAACTGTCAGATGAATTACTGTCTTGTATTGATGTCATCACACCAAATGAAACGGA
AGCGGAAGTACTCACAGGCGTGACGGTAACAGACGATGATAGCGCACAAGAAGCGGCAAACATCCTGCATTCGAAAGGCA
TTGAAATCGTCATGATCACGCTCGGTGCGAAAGGGGTGTGGTTGAGTCAAAATGGTCGTGGTGAAATCATTCCTGGCTTC
CGCGTAGAAGCAACAGATACCACTGCGGCTGGCGATACGTTTAATGGGGCATTAGTCACTGGTTTATTGGAAGACTTACC
TTTAGAATCAGCGATTAAGTTTGCCCACGCTGCAGCTGCGATCTCAGTAACTCGCTTTGGCGCGCAAACCTCCATTCCAA
CCCGTAAAGAGGTTGAGGAGTTCCTTGAACAACAATAA

Upstream 100 bases:

>100_bases
AATCTATTTGAATCGTAATACGCTTACGTTTTTTAAAAGAGCGTAAACCTATTACTCCTGTTCAAATATAAAGGGTTCAT
TCAGAACCGAGGATAACCGT

Downstream 100 bases:

>100_bases
TCAAAAGGAGAAATAGCATGGCAACGATGAAAGACATCGCAAAACTGGCAGGGGTTTCCACTTCAACTGTGAGCCATGTT
ATTAACAAAACTCGCTTTGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARLNADIGFIACVGDDSFGINIRENFKMDGID
ITGVKMQPNCPTGIAMIQVADSGENSICISAEANAKLTAEAIEPDLERIRQADYLLMQLETPMCGIEKAARIAKDAKTNV
ILNPAPARELSDELLSCIDVITPNETEAEVLTGVTVTDDDSAQEAANILHSKGIEIVMITLGAKGVWLSQNGRGEIIPGF
RVEATDTTAAGDTFNGALVTGLLEDLPLESAIKFAHAAAAISVTRFGAQTSIPTRKEVEEFLEQQ

Sequences:

>Translated_305_residues
MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARLNADIGFIACVGDDSFGINIRENFKMDGID
ITGVKMQPNCPTGIAMIQVADSGENSICISAEANAKLTAEAIEPDLERIRQADYLLMQLETPMCGIEKAARIAKDAKTNV
ILNPAPARELSDELLSCIDVITPNETEAEVLTGVTVTDDDSAQEAANILHSKGIEIVMITLGAKGVWLSQNGRGEIIPGF
RVEATDTTAAGDTFNGALVTGLLEDLPLESAIKFAHAAAAISVTRFGAQTSIPTRKEVEEFLEQQ
>Mature_305_residues
MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARLNADIGFIACVGDDSFGINIRENFKMDGID
ITGVKMQPNCPTGIAMIQVADSGENSICISAEANAKLTAEAIEPDLERIRQADYLLMQLETPMCGIEKAARIAKDAKTNV
ILNPAPARELSDELLSCIDVITPNETEAEVLTGVTVTDDDSAQEAANILHSKGIEIVMITLGAKGVWLSQNGRGEIIPGF
RVEATDTTAAGDTFNGALVTGLLEDLPLESAIKFAHAAAAISVTRFGAQTSIPTRKEVEEFLEQQ

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=40.0673400673401, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1790193, Length=302, Percent_Identity=59.9337748344371, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI87081971, Length=303, Percent_Identity=27.7227722772277, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082343, Length=309, Percent_Identity=29.126213592233, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788484, Length=283, Percent_Identity=23.321554770318, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788491, Length=295, Percent_Identity=22.3728813559322, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=37.1335504885993, Blast_Score=180, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=29.0030211480363, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=34.3234323432343, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=32.5732899022801, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32365; Mature: 32365

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARLNADIGFIAC
CCCEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHEEEEECCCEEEEEE
VGDDSFGINIRENFKMDGIDITGVKMQPNCPTGIAMIQVADSGENSICISAEANAKLTAE
ECCCCCCEEEECCCEECCEEEEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCEEEHH
AIEPDLERIRQADYLLMQLETPMCGIEKAARIAKDAKTNVILNPAPARELSDELLSCIDV
HHCHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
ITPNETEAEVLTGVTVTDDDSAQEAANILHSKGIEIVMITLGAKGVWLSQNGRGEIIPGF
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCE
RVEATDTTAAGDTFNGALVTGLLEDLPLESAIKFAHAAAAISVTRFGAQTSIPTRKEVEE
EEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHH
FLEQQ
HHHCC
>Mature Secondary Structure
MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARLNADIGFIAC
CCCEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHEEEEECCCEEEEEE
VGDDSFGINIRENFKMDGIDITGVKMQPNCPTGIAMIQVADSGENSICISAEANAKLTAE
ECCCCCCEEEECCCEECCEEEEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCEEEHH
AIEPDLERIRQADYLLMQLETPMCGIEKAARIAKDAKTNVILNPAPARELSDELLSCIDV
HHCHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
ITPNETEAEVLTGVTVTDDDSAQEAANILHSKGIEIVMITLGAKGVWLSQNGRGEIIPGF
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCE
RVEATDTTAAGDTFNGALVTGLLEDLPLESAIKFAHAAAAISVTRFGAQTSIPTRKEVEE
EEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHH
FLEQQ
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]