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The map label for this gene is mtaP [H]

Identifier: 156977352

GI number: 156977352

Start: 1317137

End: 1317868

Strand: Reverse

Name: mtaP [H]

Synonym: VIBHAR_06138

Alternate gene names: 156977352

Gene position: 1317868-1317137 (Counterclockwise)

Preceding gene: 156977353

Following gene: 156977351

Centisome position: 59.79

GC content: 49.04

Gene sequence:

>732_bases
ATGATGAAACAACCTCATATTGGTGTAGACAGCACTCAAATAGCGCCTCGAGTGATCGTCTGCGGTGAACCAGATCGAGC
AAACCGTATTGCCGCGTTGTTTGATAACGCAGAATTGGCCTCTGAGAACCGTGAATATAGAGTGTTCACTGGCACATACC
AAGGTCAGCAAATCTCAGTATGCAGTACAGGTATAGGCGCTCCTTCGATGATCATTGCGGTGGAAGAGCTAAAACAGTGT
GGTGTGACAGACGTGATTCGTGTGGGATCGGCTGGTGCGATGCAAAAAGGCATTCAACTCGGTGAGTTGATAGTGGCTGA
AGGCGCCGTCAGAGATGAAGGTGGCTCGAAAGCATACGTTCGCCCTTCGTATCCGGCTTACGCAAGCTTTTCGTTACTGA
AAGCGCTGGACAGCTATTTAGCCGAAAAAGAAGCGCGCTATCATTTAGGTGTGGTTCGCTCCCATGACAGCTTCTATACC
GACGACGAAGAAGCGATTTGCGAATACTGGAACAAGAAAGGCATCCTAGGCGCGGATATGGAAACATCAGCGCTTTTTAC
CGTCGGTCGCCTGCGTGGTCTAAACGTTGCTTCTATCTTGAGCAATGTCGTCCTGTATCAACAAAATGTTAAGGAAGGCG
TAGGGCAGTACGTAGATGAAGCGCAAGTGATGATGGAGGGGGAGCGTTTAGCATCTTACGCTGCTCTTGAAGCCTTAATT
GCGCAGAGTTAA

Upstream 100 bases:

>100_bases
CTCATGTTCATCGCAGCAAACGGCACAAGAGAGTGGGCACGTAGTGCGAAACGCAATGGTGAGAAGACCCTAACTCAAGC
GACAGCACAAGGTTAAGCCA

Downstream 100 bases:

>100_bases
CTGGATCACAGCTTAGTTAATTTTTGAAGCGGCACTTTGGTGTCGCTTTTTTATTGGCTGTCATCAAACGATTCTAGCGA
GTACAATCTATTTGAGATTG

Product: hypothetical protein

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MMKQPHIGVDSTQIAPRVIVCGEPDRANRIAALFDNAELASENREYRVFTGTYQGQQISVCSTGIGAPSMIIAVEELKQC
GVTDVIRVGSAGAMQKGIQLGELIVAEGAVRDEGGSKAYVRPSYPAYASFSLLKALDSYLAEKEARYHLGVVRSHDSFYT
DDEEAICEYWNKKGILGADMETSALFTVGRLRGLNVASILSNVVLYQQNVKEGVGQYVDEAQVMMEGERLASYAALEALI
AQS

Sequences:

>Translated_243_residues
MMKQPHIGVDSTQIAPRVIVCGEPDRANRIAALFDNAELASENREYRVFTGTYQGQQISVCSTGIGAPSMIIAVEELKQC
GVTDVIRVGSAGAMQKGIQLGELIVAEGAVRDEGGSKAYVRPSYPAYASFSLLKALDSYLAEKEARYHLGVVRSHDSFYT
DDEEAICEYWNKKGILGADMETSALFTVGRLRGLNVASILSNVVLYQQNVKEGVGQYVDEAQVMMEGERLASYAALEALI
AQS
>Mature_243_residues
MMKQPHIGVDSTQIAPRVIVCGEPDRANRIAALFDNAELASENREYRVFTGTYQGQQISVCSTGIGAPSMIIAVEELKQC
GVTDVIRVGSAGAMQKGIQLGELIVAEGAVRDEGGSKAYVRPSYPAYASFSLLKALDSYLAEKEARYHLGVVRSHDSFYT
DDEEAICEYWNKKGILGADMETSALFTVGRLRGLNVASILSNVVLYQQNVKEGVGQYVDEAQVMMEGERLASYAALEALI
AQS

Specific function: Endowed with a broad substrate specificity, being able to phosphorolytically cleave inosine, guanosine, and adenosine with a better efficiency than MTA [H]

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=248, Percent_Identity=32.258064516129, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790844, Length=216, Percent_Identity=31.9444444444444, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 26370; Mature: 26370

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKQPHIGVDSTQIAPRVIVCGEPDRANRIAALFDNAELASENREYRVFTGTYQGQQISV
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHCCCCCEEEEEECCCCCEEEE
CSTGIGAPSMIIAVEELKQCGVTDVIRVGSAGAMQKGIQLGELIVAEGAVRDEGGSKAYV
EECCCCCCHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHEECCCEECCCCCEEEE
RPSYPAYASFSLLKALDSYLAEKEARYHLGVVRSHDSFYTDDEEAICEYWNKKGILGADM
CCCCCCHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCC
ETSALFTVGRLRGLNVASILSNVVLYQQNVKEGVGQYVDEAQVMMEGERLASYAALEALI
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQS
HCC
>Mature Secondary Structure
MMKQPHIGVDSTQIAPRVIVCGEPDRANRIAALFDNAELASENREYRVFTGTYQGQQISV
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHCCCCCEEEEEECCCCCEEEE
CSTGIGAPSMIIAVEELKQCGVTDVIRVGSAGAMQKGIQLGELIVAEGAVRDEGGSKAYV
EECCCCCCHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHEECCCEECCCCCEEEE
RPSYPAYASFSLLKALDSYLAEKEARYHLGVVRSHDSFYTDDEEAICEYWNKKGILGADM
CCCCCCHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCC
ETSALFTVGRLRGLNVASILSNVVLYQQNVKEGVGQYVDEAQVMMEGERLASYAALEALI
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQS
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 7929153 [H]