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The map label for this gene is pnuC [H]

Identifier: 156977353

GI number: 156977353

Start: 1317873

End: 1318610

Strand: Reverse

Name: pnuC [H]

Synonym: VIBHAR_06139

Alternate gene names: 156977353

Gene position: 1318610-1317873 (Counterclockwise)

Preceding gene: 156977354

Following gene: 156977352

Centisome position: 59.83

GC content: 44.17

Gene sequence:

>738_bases
ATGGACCTATTTGCCCTGTTAGACATCAACAATACCCTCGTAAACATTCCTATTGGTGATGGCTACGCAATGAGTTGGAT
CGAAGCCTTTGGTACGGTTTTCGGTCTGCTTTGTATTTGGTTTGCGAGCCAAGAAAAAACCATTAACTATTTGTTTGGTT
TGCTGAATGTAACACTTTTTGCCGTTATCTTTTTCCAGATTCAGCTCTATGGATTGCTTTTGCTTCAACTGTTTTTCTTC
TGCGCCAATATTTATGGTTGGTATGCTTGGACAAGACCAAATGCACAAGGTGAGACATTAGAGGTGCGCTGGTTAAGCAA
ACAGAAGCTGATCGCGACAGGTTCAGTAAGCATTGTTGCGATTGCCCTATTAACCATCTATATCGATCCATTCTTTTTTG
CGTTGGCTAACATTGCCGTTGATACGTTAAATGTATTCGGTGCAGGTTTGTCTGAACCTGTGTTGGAGCCAGATGCTTTC
CCATTCTGGGATGCAACCATGACAGTTCTGTCTATCGTGGCGCAAATCTTGATGACACGTAAGTACGTTGAGAACTGGAT
TCTTTGGGTCGTAATCAACATCATCAGCGTTGGCATTTACGCGACACAAGGCGTGTACGCAATGTCGGTTCAATACGCGA
TTCTCATGTTCATCGCAGCAAACGGCACAAGAGAGTGGGCACGTAGTGCGAAACGCAATGGTGAGAAGACCCTAACTCAA
GCGACAGCACAAGGTTAA

Upstream 100 bases:

>100_bases
ATGATCGGGTACATCGAAGGGAGGACAAATGTCCTCCTTTTTGTTTGCTACGACACCATAAGATGAGCGCACCCCAAGCA
CAATAATAAAGGACATCTTT

Downstream 100 bases:

>100_bases
GCCAATGATGAAACAACCTCATATTGGTGTAGACAGCACTCAAATAGCGCCTCGAGTGATCGTCTGCGGTGAACCAGATC
GAGCAAACCGTATTGCCGCG

Product: hypothetical protein

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MDLFALLDINNTLVNIPIGDGYAMSWIEAFGTVFGLLCIWFASQEKTINYLFGLLNVTLFAVIFFQIQLYGLLLLQLFFF
CANIYGWYAWTRPNAQGETLEVRWLSKQKLIATGSVSIVAIALLTIYIDPFFFALANIAVDTLNVFGAGLSEPVLEPDAF
PFWDATMTVLSIVAQILMTRKYVENWILWVVINIISVGIYATQGVYAMSVQYAILMFIAANGTREWARSAKRNGEKTLTQ
ATAQG

Sequences:

>Translated_245_residues
MDLFALLDINNTLVNIPIGDGYAMSWIEAFGTVFGLLCIWFASQEKTINYLFGLLNVTLFAVIFFQIQLYGLLLLQLFFF
CANIYGWYAWTRPNAQGETLEVRWLSKQKLIATGSVSIVAIALLTIYIDPFFFALANIAVDTLNVFGAGLSEPVLEPDAF
PFWDATMTVLSIVAQILMTRKYVENWILWVVINIISVGIYATQGVYAMSVQYAILMFIAANGTREWARSAKRNGEKTLTQ
ATAQG
>Mature_245_residues
MDLFALLDINNTLVNIPIGDGYAMSWIEAFGTVFGLLCIWFASQEKTINYLFGLLNVTLFAVIFFQIQLYGLLLLQLFFF
CANIYGWYAWTRPNAQGETLEVRWLSKQKLIATGSVSIVAIALLTIYIDPFFFALANIAVDTLNVFGAGLSEPVLEPDAF
PFWDATMTVLSIVAQILMTRKYVENWILWVVINIISVGIYATQGVYAMSVQYAILMFIAANGTREWARSAKRNGEKTLTQ
ATAQG

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=242, Percent_Identity=58.2644628099173, Blast_Score=263, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27434; Mature: 27434

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFALLDINNTLVNIPIGDGYAMSWIEAFGTVFGLLCIWFASQEKTINYLFGLLNVTLF
CCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AVIFFQIQLYGLLLLQLFFFCANIYGWYAWTRPNAQGETLEVRWLSKQKLIATGSVSIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCEEECCCHHHHH
IALLTIYIDPFFFALANIAVDTLNVFGAGLSEPVLEPDAFPFWDATMTVLSIVAQILMTR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KYVENWILWVVINIISVGIYATQGVYAMSVQYAILMFIAANGTREWARSAKRNGEKTLTQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
ATAQG
HHCCC
>Mature Secondary Structure
MDLFALLDINNTLVNIPIGDGYAMSWIEAFGTVFGLLCIWFASQEKTINYLFGLLNVTLF
CCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AVIFFQIQLYGLLLLQLFFFCANIYGWYAWTRPNAQGETLEVRWLSKQKLIATGSVSIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCEEECCCHHHHH
IALLTIYIDPFFFALANIAVDTLNVFGAGLSEPVLEPDAFPFWDATMTVLSIVAQILMTR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KYVENWILWVVINIISVGIYATQGVYAMSVQYAILMFIAANGTREWARSAKRNGEKTLTQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
ATAQG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]