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The map label for this gene is gsk [H]

Identifier: 156977156

GI number: 156977156

Start: 1125867

End: 1127171

Strand: Direct

Name: gsk [H]

Synonym: VIBHAR_05942

Alternate gene names: 156977156

Gene position: 1125867-1127171 (Clockwise)

Preceding gene: 156977155

Following gene: 156977157

Centisome position: 51.08

GC content: 46.13

Gene sequence:

>1305_bases
ATGAAGTTTCCTGGTCAGCGAAAATCTAAACACTACTTTCCAACTCACGCTCGAGATCCATTAGTCAACCAAATCCAACA
GGCGCCTAAGCTGTACCGCCCAACGATTGTCGGTGTTGGTCAAACCATCGTTGATATCGAAGCGCGCGTAGACGATGCGT
TTTTAGAAAAATACAACCTTAGTAAAGGTCATTCTCTCGTTCTTGAAGAGAACAAAGCAGACGCATTGTATGAAGAGTTA
GTAGAACAAGGTCTGATTACTCACCAATACCCTGGTGATACTATCGGCAACACACTACATAACTACTCTGTTTTGGCTGA
TAGCAAATCAGTACTCTTAGGCGTAATGTCGAAGAACATCCAAGTAGGTTCTTTTGCATACCGCTACCTATGCCGCACCT
CTTCTCGCATGAACCTTAACCACTTACAAACAGTAGATGGTCCTATTGGTCGTTGCTACACGCTAATTTCTCAAGACGGC
GAGCGTACCTTCGCAATTAACGAAGGCCACATGAACAAGCTGTCTCCGGAAAGCATCCCTGAAGAAGTCTTTACTAAAGC
ATCAGCTCTTGTGGTTTCTTCTTACCTTATGCGTGGTAAGAAAGAGGACCAAATGCCTCAAGCGGTTCAGCGCGCAATCG
AATTTGCTAAGAAGCACGAAGTCCCTGTAGTACTGACTCTAGGTACAAAATACGTGATTGAAGGCAATGCAGAATGGTGG
CAAGAGTACATTCGCGACAACGTATCTGTCGTTGCAATGAACGAAGAAGAAGGCGCAGCACTAACAGGTGAAACCGACCC
TCTTGCAGCTGCAGATAAAGCACTTGAGTGGGTCGACCTTGTACTTTGTACTGCTGGCCCAGATGGTCTATACATGGCGG
GTTACACGGAAGAGAAAGTAAAACGTGAAACCACACATGACATTCTTGAGGGCTCTATCGAAGAGTTCAACAAGTTTGAA
TTTAGCCGTGCAATGCGCAAAGACGACTGTAAAGCACCAATGAAAGTGTACTCTCATATTGGTCCTTACCTTGGTGGCCC
TCTTGAAATCAAGAACACCAACGGCGCAGGTGATGCGGCACTGTCTGCACTTCTGCACGATATGGCGGCTAACTCTTTCC
ACCAGAAAGAAGTACCAGGTTCAGAGAAACACGAAGTACGTTGCCTAACTTACTCTTCTCTATCTCAGATTTGTAAGTAC
GCAAACCGCGTAAGCTACGAAGTACTAACTCAGCACTCTCCTCGCCTATCTCGCGCACTGCCAGAGCGTGAAGACAGCTT
AGAAGAGACATACTGGGATCGCTAA

Upstream 100 bases:

>100_bases
CTGCATTTTTCAGCGGGCAAATTTCTTTGTAATAAAACGCAACGAATTTCAAAATTTTGTGATACAATCCCGCCTCTTTT
TTTCTCACTCAAGAACAAGC

Downstream 100 bases:

>100_bases
GAACCAAGCATTTAGAGCAAAAAACACGCAAAGGTCACCATTAGGTGGCCTTTTTGTTTTGATCTAGCGCAGTATTTAGT
GTTTTTTGTTATGATGTAGC

Product: inosine-guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGQRKSKHYFPTHARDPLVNQIQQAPKLYRPTIVGVGQTIVDIEARVDDAFLEKYNLSKGHSLVLEENKADALYEEL
VEQGLITHQYPGDTIGNTLHNYSVLADSKSVLLGVMSKNIQVGSFAYRYLCRTSSRMNLNHLQTVDGPIGRCYTLISQDG
ERTFAINEGHMNKLSPESIPEEVFTKASALVVSSYLMRGKKEDQMPQAVQRAIEFAKKHEVPVVLTLGTKYVIEGNAEWW
QEYIRDNVSVVAMNEEEGAALTGETDPLAAADKALEWVDLVLCTAGPDGLYMAGYTEEKVKRETTHDILEGSIEEFNKFE
FSRAMRKDDCKAPMKVYSHIGPYLGGPLEIKNTNGAGDAALSALLHDMAANSFHQKEVPGSEKHEVRCLTYSSLSQICKY
ANRVSYEVLTQHSPRLSRALPEREDSLEETYWDR

Sequences:

>Translated_434_residues
MKFPGQRKSKHYFPTHARDPLVNQIQQAPKLYRPTIVGVGQTIVDIEARVDDAFLEKYNLSKGHSLVLEENKADALYEEL
VEQGLITHQYPGDTIGNTLHNYSVLADSKSVLLGVMSKNIQVGSFAYRYLCRTSSRMNLNHLQTVDGPIGRCYTLISQDG
ERTFAINEGHMNKLSPESIPEEVFTKASALVVSSYLMRGKKEDQMPQAVQRAIEFAKKHEVPVVLTLGTKYVIEGNAEWW
QEYIRDNVSVVAMNEEEGAALTGETDPLAAADKALEWVDLVLCTAGPDGLYMAGYTEEKVKRETTHDILEGSIEEFNKFE
FSRAMRKDDCKAPMKVYSHIGPYLGGPLEIKNTNGAGDAALSALLHDMAANSFHQKEVPGSEKHEVRCLTYSSLSQICKY
ANRVSYEVLTQHSPRLSRALPEREDSLEETYWDR
>Mature_434_residues
MKFPGQRKSKHYFPTHARDPLVNQIQQAPKLYRPTIVGVGQTIVDIEARVDDAFLEKYNLSKGHSLVLEENKADALYEEL
VEQGLITHQYPGDTIGNTLHNYSVLADSKSVLLGVMSKNIQVGSFAYRYLCRTSSRMNLNHLQTVDGPIGRCYTLISQDG
ERTFAINEGHMNKLSPESIPEEVFTKASALVVSSYLMRGKKEDQMPQAVQRAIEFAKKHEVPVVLTLGTKYVIEGNAEWW
QEYIRDNVSVVAMNEEEGAALTGETDPLAAADKALEWVDLVLCTAGPDGLYMAGYTEEKVKRETTHDILEGSIEEFNKFE
FSRAMRKDDCKAPMKVYSHIGPYLGGPLEIKNTNGAGDAALSALLHDMAANSFHQKEVPGSEKHEVRCLTYSSLSQICKY
ANRVSYEVLTQHSPRLSRALPEREDSLEETYWDR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=66.8202764976959, Blast_Score=639, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48715; Mature: 48715

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGQRKSKHYFPTHARDPLVNQIQQAPKLYRPTIVGVGQTIVDIEARVDDAFLEKYNL
CCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHCCEEEECCCCEEEHHHHHHHHHHHHHCC
SKGHSLVLEENKADALYEELVEQGLITHQYPGDTIGNTLHNYSVLADSKSVLLGVMSKNI
CCCCEEEEECCCHHHHHHHHHHCCCEECCCCCCHHHHHHHCCCEECCCHHHHHHHHHCCC
QVGSFAYRYLCRTSSRMNLNHLQTVDGPIGRCYTLISQDGERTFAINEGHMNKLSPESIP
EEHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
EEVFTKASALVVSSYLMRGKKEDQMPQAVQRAIEFAKKHEVPVVLTLGTKYVIEGNAEWW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
QEYIRDNVSVVAMNEEEGAALTGETDPLAAADKALEWVDLVLCTAGPDGLYMAGYTEEKV
HHHHHCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHEEEEECCCCCCEECCCCHHHH
KRETTHDILEGSIEEFNKFEFSRAMRKDDCKAPMKVYSHIGPYLGGPLEIKNTNGAGDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHCCCCEEEECCCCCHHHH
LSALLHDMAANSFHQKEVPGSEKHEVRCLTYSSLSQICKYANRVSYEVLTQHSPRLSRAL
HHHHHHHHHHCCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHCCCCHHHHHC
PEREDSLEETYWDR
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGQRKSKHYFPTHARDPLVNQIQQAPKLYRPTIVGVGQTIVDIEARVDDAFLEKYNL
CCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHCCEEEECCCCEEEHHHHHHHHHHHHHCC
SKGHSLVLEENKADALYEELVEQGLITHQYPGDTIGNTLHNYSVLADSKSVLLGVMSKNI
CCCCEEEEECCCHHHHHHHHHHCCCEECCCCCCHHHHHHHCCCEECCCHHHHHHHHHCCC
QVGSFAYRYLCRTSSRMNLNHLQTVDGPIGRCYTLISQDGERTFAINEGHMNKLSPESIP
EEHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
EEVFTKASALVVSSYLMRGKKEDQMPQAVQRAIEFAKKHEVPVVLTLGTKYVIEGNAEWW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
QEYIRDNVSVVAMNEEEGAALTGETDPLAAADKALEWVDLVLCTAGPDGLYMAGYTEEKV
HHHHHCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHEEEEECCCCCCEECCCCHHHH
KRETTHDILEGSIEEFNKFEFSRAMRKDDCKAPMKVYSHIGPYLGGPLEIKNTNGAGDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHCCCCEEEECCCCCHHHH
LSALLHDMAANSFHQKEVPGSEKHEVRCLTYSSLSQICKYANRVSYEVLTQHSPRLSRAL
HHHHHHHHHHCCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHCCCCHHHHHC
PEREDSLEETYWDR
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]