Click here to switch to the map view.

The map label for this gene is hpuB [H]

Identifier: 156977004

GI number: 156977004

Start: 975411

End: 977549

Strand: Direct

Name: hpuB [H]

Synonym: VIBHAR_05789

Alternate gene names: 156977004

Gene position: 975411-977549 (Clockwise)

Preceding gene: 156977002

Following gene: 156977006

Centisome position: 44.26

GC content: 43.76

Gene sequence:

>2139_bases
ATGTATAAAAAATCAATTTTGTCAGCCTCTATTCTTATCGCCCTCTCCCAAGGTGCTTACGCTGAAGATACATCCACATT
TAATGAAGTCGTTGTATCAGCAACTCGTACAAACCAAACTATGGATACTGTAGCAGCTTCTGTTGCCGTTGTTTCTGAGA
AAGATCTCGAAGAGAACATGGCAAAAGATCTCAATGATGTATTCGAGTACACCCCTGGTGTTACGGTGAATGGCACTCAA
CGCCAAGGTGTTCAAAGCATTAACATTCGTGGCATGGAAGGTAAACGAGTGAAAATCTTGGTGGATGGTGCATCTCAACC
AGGTGTTTTCGATGGCGGCCCATACTCTTTCATCAACTCTAGTGCGGTTACTGTAGATCCAGACATGCTAAAGAGCGTTG
AGATCGTAAAAGGTGCTGCTTCTAGTTTGCATGGTAGCGATGCTATTGGTGGTGTTGTGGCGTTTGAAACCAAAGATCCA
AGTGATTTCTTAAAAGATGGCAAAGACTTCGGTGGTCAAGCTAAGCTTTCTTACTCTTCAGAAGACAACTCATTTAGTGA
GCATGTTGCTTTGGCAAAGCAGTTTGATAATGTTGAAGCGTTGGTAGCTTACACACGCCGTGATGGCTCTGAACTACAAA
ATTTCGCAAAAGCCCCTTATGACGATTATTCAGTAACAGACCAAGATTATTACAAGAACGATTTGTTGGTAAAACTGCAG
TCGCAACTTAATGACGATCACCGTTTGGAGTTTTTGGGCGAAGTTATTTACAACCAAACGGATTCAGACATTGCGAGTTC
GTCTTACAAAAACTTCAATGCTGAAGACACAACCAAACAAAACCGTCTAGGTCTGAAACACATTTGGTTCGCAGATTTGG
CCATCTCTGACACCATCACTTCTCAACTAACTTGGATCAGTAAGGAAGAGAATGGCGTAACAAATCGATTTAAAGAAGCC
AGCGCAGGTCACCCACCTTGGGTTCCAGCAAACGGTGATAACCAGCAGAAGAAAGATTACGAATACACGGAAGATAAAAT
TGAATTTGAAACTCAGCTAGATAAAGAGATTCAAAACCACTACCTCGTGTACGGTTTATCATACAAACATAGTGACATAA
GCAATACTAACCGCGAGTTTAACTCTGATCCTAATACTCCAGACAAGGTTTATGTCTACACACCAGACGCGAAAGAACAA
AGCTTTGGCCTGTTCCTTCAAGACGAAATCGCGTTGCTAAACGACAAGCTAATTTTAACACCGGGTGTTCGCTACGACTA
CTTCTCTACCGATCCATCAGATACGTCTGACGAGTCATTCAAGAAGTTTAGTGACTCTGCGTTTACTGGCCGCTTAGGTG
CGACTTACAAAGTGTCTCAACCAGGGACTGTGTTCGCTCAAGTAAGCCAAGGTTTCCGAGCTCCGTCATTTGATGAGCTT
TACTACACGTATGACAACCCAGGCCATGGTTACACCAACCGACCTAACCCAGATCTAGAATCAGAAAAGAGCTTGTCTTA
CGAATTGGGTTACCGTCATAACACAGCCGCATCGGCAACCGAGTTCGCGCTTTACTACAGCGATTTCACGGATTTTATTG
ATCAAACATCAACAAGTAATGGCGGCTTAACAGAGTACACATTCATCAACATCAATGAAGCAACCGTAAAAGGTGTTGAA
CTGTCTAACAGCCTTGATTGGCATGCGATTGCAAGCCTTCCGCAGGGTGTTACAACGCGCGTAGCCGCTGCATACACTGA
AGGTGAAGATGGCAATGGTAACCCACTTAATAGTGTCAACCCTTGGAATGCTGTGGCAGCGGTTAACTACGACTCGCCAA
ACGCGCTTTGGGGTACAAGCTTAAAAGTTAACTACACCGCGAAGAAGTCTGACAGTGATATCAACTCAGATGGTAATAAT
GGCGGAACTAAAGACCAAGTTGCACTACCATCAGCGACAGTTGTTGATCTAACCGCTTACTATAAGCCAATGAAAGACCT
GACCGTTCGTGCAGGTGTGATGAACTTGACGAATGAAGAGTACTACTTGTGGAACGATGTACGTGGTGAAACTGAGCTAA
GCCGTGATATCACGCAGGCAGAGCGTAACTACAACATTAGTGTCAAATACGAGTTCTAA

Upstream 100 bases:

>100_bases
TAACATTAAACAATAATTGGAATGATAGTAATTACCATTTAGATCTAATAAGATACCGCACGTTGTTATTGCCTCTTATG
GATTTAAGGTATTGAAGCCA

Downstream 100 bases:

>100_bases
GTGTTACAAACACAAAAAAGCCAGCATTATGCTTAACTCCTATCACTTAACGTGTTTGGAGCGAACTGGATAGCGAGTCT
TACTCATACGAACGGTCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MYKKSILSASILIALSQGAYAEDTSTFNEVVVSATRTNQTMDTVAASVAVVSEKDLEENMAKDLNDVFEYTPGVTVNGTQ
RQGVQSINIRGMEGKRVKILVDGASQPGVFDGGPYSFINSSAVTVDPDMLKSVEIVKGAASSLHGSDAIGGVVAFETKDP
SDFLKDGKDFGGQAKLSYSSEDNSFSEHVALAKQFDNVEALVAYTRRDGSELQNFAKAPYDDYSVTDQDYYKNDLLVKLQ
SQLNDDHRLEFLGEVIYNQTDSDIASSSYKNFNAEDTTKQNRLGLKHIWFADLAISDTITSQLTWISKEENGVTNRFKEA
SAGHPPWVPANGDNQQKKDYEYTEDKIEFETQLDKEIQNHYLVYGLSYKHSDISNTNREFNSDPNTPDKVYVYTPDAKEQ
SFGLFLQDEIALLNDKLILTPGVRYDYFSTDPSDTSDESFKKFSDSAFTGRLGATYKVSQPGTVFAQVSQGFRAPSFDEL
YYTYDNPGHGYTNRPNPDLESEKSLSYELGYRHNTAASATEFALYYSDFTDFIDQTSTSNGGLTEYTFININEATVKGVE
LSNSLDWHAIASLPQGVTTRVAAAYTEGEDGNGNPLNSVNPWNAVAAVNYDSPNALWGTSLKVNYTAKKSDSDINSDGNN
GGTKDQVALPSATVVDLTAYYKPMKDLTVRAGVMNLTNEEYYLWNDVRGETELSRDITQAERNYNISVKYEF

Sequences:

>Translated_712_residues
MYKKSILSASILIALSQGAYAEDTSTFNEVVVSATRTNQTMDTVAASVAVVSEKDLEENMAKDLNDVFEYTPGVTVNGTQ
RQGVQSINIRGMEGKRVKILVDGASQPGVFDGGPYSFINSSAVTVDPDMLKSVEIVKGAASSLHGSDAIGGVVAFETKDP
SDFLKDGKDFGGQAKLSYSSEDNSFSEHVALAKQFDNVEALVAYTRRDGSELQNFAKAPYDDYSVTDQDYYKNDLLVKLQ
SQLNDDHRLEFLGEVIYNQTDSDIASSSYKNFNAEDTTKQNRLGLKHIWFADLAISDTITSQLTWISKEENGVTNRFKEA
SAGHPPWVPANGDNQQKKDYEYTEDKIEFETQLDKEIQNHYLVYGLSYKHSDISNTNREFNSDPNTPDKVYVYTPDAKEQ
SFGLFLQDEIALLNDKLILTPGVRYDYFSTDPSDTSDESFKKFSDSAFTGRLGATYKVSQPGTVFAQVSQGFRAPSFDEL
YYTYDNPGHGYTNRPNPDLESEKSLSYELGYRHNTAASATEFALYYSDFTDFIDQTSTSNGGLTEYTFININEATVKGVE
LSNSLDWHAIASLPQGVTTRVAAAYTEGEDGNGNPLNSVNPWNAVAAVNYDSPNALWGTSLKVNYTAKKSDSDINSDGNN
GGTKDQVALPSATVVDLTAYYKPMKDLTVRAGVMNLTNEEYYLWNDVRGETELSRDITQAERNYNISVKYEF
>Mature_712_residues
MYKKSILSASILIALSQGAYAEDTSTFNEVVVSATRTNQTMDTVAASVAVVSEKDLEENMAKDLNDVFEYTPGVTVNGTQ
RQGVQSINIRGMEGKRVKILVDGASQPGVFDGGPYSFINSSAVTVDPDMLKSVEIVKGAASSLHGSDAIGGVVAFETKDP
SDFLKDGKDFGGQAKLSYSSEDNSFSEHVALAKQFDNVEALVAYTRRDGSELQNFAKAPYDDYSVTDQDYYKNDLLVKLQ
SQLNDDHRLEFLGEVIYNQTDSDIASSSYKNFNAEDTTKQNRLGLKHIWFADLAISDTITSQLTWISKEENGVTNRFKEA
SAGHPPWVPANGDNQQKKDYEYTEDKIEFETQLDKEIQNHYLVYGLSYKHSDISNTNREFNSDPNTPDKVYVYTPDAKEQ
SFGLFLQDEIALLNDKLILTPGVRYDYFSTDPSDTSDESFKKFSDSAFTGRLGATYKVSQPGTVFAQVSQGFRAPSFDEL
YYTYDNPGHGYTNRPNPDLESEKSLSYELGYRHNTAASATEFALYYSDFTDFIDQTSTSNGGLTEYTFININEATVKGVE
LSNSLDWHAIASLPQGVTTRVAAAYTEGEDGNGNPLNSVNPWNAVAAVNYDSPNALWGTSLKVNYTAKKSDSDINSDGNN
GGTKDQVALPSATVVDLTAYYKPMKDLTVRAGVMNLTNEEYYLWNDVRGETELSRDITQAERNYNISVKYEF

Specific function: Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=160, Percent_Identity=35.625, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788478, Length=164, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78865; Mature: 78865

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKKSILSASILIALSQGAYAEDTSTFNEVVVSATRTNQTMDTVAASVAVVSEKDLEENM
CCCHHHHCEEEEEEECCCCCCCCCHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AKDLNDVFEYTPGVTVNGTQRQGVQSINIRGMEGKRVKILVDGASQPGVFDGGPYSFINS
HHHHHHHHHHCCCCEECCHHHCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHCCC
SAVTVDPDMLKSVEIVKGAASSLHGSDAIGGVVAFETKDPSDFLKDGKDFGGQAKLSYSS
CEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHCCCCCCCEEEEEECC
EDNSFSEHVALAKQFDNVEALVAYTRRDGSELQNFAKAPYDDYSVTDQDYYKNDLLVKLQ
CCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHCCHHEEEEH
SQLNDDHRLEFLGEVIYNQTDSDIASSSYKNFNAEDTTKQNRLGLKHIWFADLAISDTIT
HHCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHCCCCEEEEEEHEEHHHHHH
SQLTWISKEENGVTNRFKEASAGHPPWVPANGDNQQKKDYEYTEDKIEFETQLDKEIQNH
HHEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
YLVYGLSYKHSDISNTNREFNSDPNTPDKVYVYTPDAKEQSFGLFLQDEIALLNDKLILT
EEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHCCCEEEC
PGVRYDYFSTDPSDTSDESFKKFSDSAFTGRLGATYKVSQPGTVFAQVSQGFRAPSFDEL
CCCCEEECCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCEEHHHHHCCCCCCCCCCE
YYTYDNPGHGYTNRPNPDLESEKSLSYELGYRHNTAASATEFALYYSDFTDFIDQTSTSN
EEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHEEEEEHHHHHHHHHHCCCCC
GGLTEYTFININEATVKGVELSNSLDWHAIASLPQGVTTRVAAAYTEGEDGNGNPLNSVN
CCCEEEEEEECCHHEEEEEEECCCCCHHHHHHCCCCHHHHEEEEEECCCCCCCCCCCCCC
PWNAVAAVNYDSPNALWGTSLKVNYTAKKSDSDINSDGNNGGTKDQVALPSATVVDLTAY
CCCEEEEEECCCCCCEECCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEEHHHH
YKPMKDLTVRAGVMNLTNEEYYLWNDVRGETELSRDITQAERNYNISVKYEF
HCCHHHHEEHHHHEECCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEEEC
>Mature Secondary Structure
MYKKSILSASILIALSQGAYAEDTSTFNEVVVSATRTNQTMDTVAASVAVVSEKDLEENM
CCCHHHHCEEEEEEECCCCCCCCCHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AKDLNDVFEYTPGVTVNGTQRQGVQSINIRGMEGKRVKILVDGASQPGVFDGGPYSFINS
HHHHHHHHHHCCCCEECCHHHCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHCCC
SAVTVDPDMLKSVEIVKGAASSLHGSDAIGGVVAFETKDPSDFLKDGKDFGGQAKLSYSS
CEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHCCCCCCCEEEEEECC
EDNSFSEHVALAKQFDNVEALVAYTRRDGSELQNFAKAPYDDYSVTDQDYYKNDLLVKLQ
CCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHCCHHEEEEH
SQLNDDHRLEFLGEVIYNQTDSDIASSSYKNFNAEDTTKQNRLGLKHIWFADLAISDTIT
HHCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHCCCCEEEEEEHEEHHHHHH
SQLTWISKEENGVTNRFKEASAGHPPWVPANGDNQQKKDYEYTEDKIEFETQLDKEIQNH
HHEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
YLVYGLSYKHSDISNTNREFNSDPNTPDKVYVYTPDAKEQSFGLFLQDEIALLNDKLILT
EEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHCCCEEEC
PGVRYDYFSTDPSDTSDESFKKFSDSAFTGRLGATYKVSQPGTVFAQVSQGFRAPSFDEL
CCCCEEECCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCEEHHHHHCCCCCCCCCCE
YYTYDNPGHGYTNRPNPDLESEKSLSYELGYRHNTAASATEFALYYSDFTDFIDQTSTSN
EEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHEEEEEHHHHHHHHHHCCCCC
GGLTEYTFININEATVKGVELSNSLDWHAIASLPQGVTTRVAAAYTEGEDGNGNPLNSVN
CCCEEEEEEECCHHEEEEEEECCCCCHHHHHHCCCCHHHHEEEEEECCCCCCCCCCCCCC
PWNAVAAVNYDSPNALWGTSLKVNYTAKKSDSDINSDGNNGGTKDQVALPSATVVDLTAY
CCCEEEEEECCCCCCEECCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEEHHHH
YKPMKDLTVRAGVMNLTNEEYYLWNDVRGETELSRDITQAERNYNISVKYEF
HCCHHHHEEHHHHEECCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]