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The map label for this gene is sdaC [H]

Identifier: 156976804

GI number: 156976804

Start: 782687

End: 783943

Strand: Reverse

Name: sdaC [H]

Synonym: VIBHAR_05580

Alternate gene names: 156976804

Gene position: 783943-782687 (Counterclockwise)

Preceding gene: 156976817

Following gene: 156976802

Centisome position: 35.57

GC content: 45.74

Gene sequence:

>1257_bases
GTGAAAGAATCTCGAGATACGTTAAATTTTAGTGAATTAAACACCACAAATACTTGGACAAAGCACGATACACACTGGCT
ATTAAGCTTGTTTGGTACTGCTGTTGGTGCGGGTATTCTATTTTTGCCGATTAACCTTGGTATTGGCGGCTTTTGGCCTC
TAGTTGTGATGGCCGTTCTTGCATACCCAATGACTTACTTAGCTCACCGTGGTCTTGCCCGATTTGTCCTGTCCTCAAAG
ATCAAGAACGCTGATTTTACCGATGTGGTAGAAGAACACTTTGGCGCGAAAGCGGGTCGTTCAATTTCGCTGCTATACTT
CCTCTCTATCTTCCCAATCCTCCTAATCTATGGCGTTGGCATTACCAATACTGTCGACAGCTTTATGGTCAATCAAGCGG
GTATGGAGCCTTTACCGCGTGCCCTACTGTCTGGCGTATTAGTGTTTAGCTTAATTGCTATCATGATGGCGGGTGAAAAA
GTAATGCTGCGTGCCTTTGCCATCATGGTTTATCCGTTGGTGGCGATTCTGGCGTTTCTATCATTCTACTTAATGCCAAA
CTGGAGCATGCCAGTAATGGACGCGCCAGAAATGTCGTCTTTTGCAAGCACCATGTGGTTGGCGATTCCTGTCGTCATTT
TTTCTTTCAGCCACGCGGCAGCAATCTCAAGCTTTGCCAATGTTCAACGTCGTCACTACGGTGAGGCAGCGGATGCGAAG
TCTGAGCTTATTTTACGTCGCACTAGCATCATGCTGATCGCTTTTGTGCTGTTGTTTGTCTTCTCTTGCGTGCTTGCGCT
ATCTCCGCAGCAGCTGGCAGAAGCAAAAGAGCAAAACGTATCTGTGTTGTCTTACTTAGCAAACGCTACGGACAATCCTT
TTATTGCAACGTTAGGTCCACTTGTCGCATTTGTCGCGATCACCTCTTCTTTCCTTGGTCACTTCCTTGGTGCACGTGAA
AGCTTGAATGGTTTGATCACTAAGCATTCTGATATGCCAAAGCAACGCGTAGATCGCATCAGTGTTGTTGTACTGTTTGT
GTCTATTTGGATTGCTGCGATCATGAACCCTAGCATCTTGGGGATGATGGAAGCCCTGTCGGGACCTGTCATCGCAATGA
TCTTGTTCATTATGCCAATGCTAGCGGTATACAAAGTAAAAGGACTGCAGAAGTATCGTGGAAAAGCATCGACCTACTTT
GTACTTATGACGGGAGTTATCGCAGTAAGTGCGTTGGTTTTTAGCTTGTTGAGTTAA

Upstream 100 bases:

>100_bases
ACCTTTTCACTAGCACGATTCACCACAAACTCGATGTGATAACAATCACTAAAACATATACCATCCGCGCGATTATTATT
TTTATAAAAGCGAGTTTTAA

Downstream 100 bases:

>100_bases
GAATAGAGACTTAGATAGGATTTTCAGGGGAATACCTTATTTTTTGTTAAGGTAATTCCCTGAATTTTGACATATTTTCT
TAGCAGTACTGATGAACTAC

Product: hypothetical protein

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKESRDTLNFSELNTTNTWTKHDTHWLLSLFGTAVGAGILFLPINLGIGGFWPLVVMAVLAYPMTYLAHRGLARFVLSSK
IKNADFTDVVEEHFGAKAGRSISLLYFLSIFPILLIYGVGITNTVDSFMVNQAGMEPLPRALLSGVLVFSLIAIMMAGEK
VMLRAFAIMVYPLVAILAFLSFYLMPNWSMPVMDAPEMSSFASTMWLAIPVVIFSFSHAAAISSFANVQRRHYGEAADAK
SELILRRTSIMLIAFVLLFVFSCVLALSPQQLAEAKEQNVSVLSYLANATDNPFIATLGPLVAFVAITSSFLGHFLGARE
SLNGLITKHSDMPKQRVDRISVVVLFVSIWIAAIMNPSILGMMEALSGPVIAMILFIMPMLAVYKVKGLQKYRGKASTYF
VLMTGVIAVSALVFSLLS

Sequences:

>Translated_418_residues
MKESRDTLNFSELNTTNTWTKHDTHWLLSLFGTAVGAGILFLPINLGIGGFWPLVVMAVLAYPMTYLAHRGLARFVLSSK
IKNADFTDVVEEHFGAKAGRSISLLYFLSIFPILLIYGVGITNTVDSFMVNQAGMEPLPRALLSGVLVFSLIAIMMAGEK
VMLRAFAIMVYPLVAILAFLSFYLMPNWSMPVMDAPEMSSFASTMWLAIPVVIFSFSHAAAISSFANVQRRHYGEAADAK
SELILRRTSIMLIAFVLLFVFSCVLALSPQQLAEAKEQNVSVLSYLANATDNPFIATLGPLVAFVAITSSFLGHFLGARE
SLNGLITKHSDMPKQRVDRISVVVLFVSIWIAAIMNPSILGMMEALSGPVIAMILFIMPMLAVYKVKGLQKYRGKASTYF
VLMTGVIAVSALVFSLLS
>Mature_418_residues
MKESRDTLNFSELNTTNTWTKHDTHWLLSLFGTAVGAGILFLPINLGIGGFWPLVVMAVLAYPMTYLAHRGLARFVLSSK
IKNADFTDVVEEHFGAKAGRSISLLYFLSIFPILLIYGVGITNTVDSFMVNQAGMEPLPRALLSGVLVFSLIAIMMAGEK
VMLRAFAIMVYPLVAILAFLSFYLMPNWSMPVMDAPEMSSFASTMWLAIPVVIFSFSHAAAISSFANVQRRHYGEAADAK
SELILRRTSIMLIAFVLLFVFSCVLALSPQQLAEAKEQNVSVLSYLANATDNPFIATLGPLVAFVAITSSFLGHFLGARE
SLNGLITKHSDMPKQRVDRISVVVLFVSIWIAAIMNPSILGMMEALSGPVIAMILFIMPMLAVYKVKGLQKYRGKASTYF
VLMTGVIAVSALVFSLLS

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=428, Percent_Identity=49.5327102803738, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1789504, Length=434, Percent_Identity=38.9400921658986, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI1789211, Length=410, Percent_Identity=36.3414634146341, Blast_Score=254, Evalue=9e-69,
Organism=Escherichia coli, GI1789961, Length=411, Percent_Identity=27.4939172749392, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI145693183, Length=422, Percent_Identity=25.5924170616114, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 45766; Mature: 45766

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESRDTLNFSELNTTNTWTKHDTHWLLSLFGTAVGAGILFLPINLGIGGFWPLVVMAVL
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHCCCCCHHHHHHHHHH
AYPMTYLAHRGLARFVLSSKIKNADFTDVVEEHFGAKAGRSISLLYFLSIFPILLIYGVG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
ITNTVDSFMVNQAGMEPLPRALLSGVLVFSLIAIMMAGEKVMLRAFAIMVYPLVAILAFL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SFYLMPNWSMPVMDAPEMSSFASTMWLAIPVVIFSFSHAAAISSFANVQRRHYGEAADAK
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SELILRRTSIMLIAFVLLFVFSCVLALSPQQLAEAKEQNVSVLSYLANATDNPFIATLGP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHH
LVAFVAITSSFLGHFLGARESLNGLITKHSDMPKQRVDRISVVVLFVSIWIAAIMNPSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
GMMEALSGPVIAMILFIMPMLAVYKVKGLQKYRGKASTYFVLMTGVIAVSALVFSLLS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKESRDTLNFSELNTTNTWTKHDTHWLLSLFGTAVGAGILFLPINLGIGGFWPLVVMAVL
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHCCCCCHHHHHHHHHH
AYPMTYLAHRGLARFVLSSKIKNADFTDVVEEHFGAKAGRSISLLYFLSIFPILLIYGVG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
ITNTVDSFMVNQAGMEPLPRALLSGVLVFSLIAIMMAGEKVMLRAFAIMVYPLVAILAFL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SFYLMPNWSMPVMDAPEMSSFASTMWLAIPVVIFSFSHAAAISSFANVQRRHYGEAADAK
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SELILRRTSIMLIAFVLLFVFSCVLALSPQQLAEAKEQNVSVLSYLANATDNPFIATLGP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHH
LVAFVAITSSFLGHFLGARESLNGLITKHSDMPKQRVDRISVVVLFVSIWIAAIMNPSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
GMMEALSGPVIAMILFIMPMLAVYKVKGLQKYRGKASTYFVLMTGVIAVSALVFSLLS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]