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The map label for this gene is etfA [H]

Identifier: 156976774

GI number: 156976774

Start: 754393

End: 755358

Strand: Direct

Name: etfA [H]

Synonym: VIBHAR_05549

Alternate gene names: 156976774

Gene position: 754393-755358 (Clockwise)

Preceding gene: 156976773

Following gene: 156976776

Centisome position: 34.23

GC content: 48.96

Gene sequence:

>966_bases
ATGGAAAACAAACCGTTAGCAACCTTGGTCATTGTGGAACACGATAACCAATCACTTTCAGTGGATACATTACGCGCATT
GAGTGCGGCTTCTGATATTCAACAAGACGGTACACCTTTGCCTGTAACGGCGTTGCTCATCGGCCATCATTGCGGTTCAG
TATTGGGCGAGTTGAAGTGTGTACAAGGTATTTCGCAGATCATCGTGATTGATGCTGCCGAATATCAGCATCCGTTGGCA
GAAAACCTGTCGACATTAATTGCCGACGTTGGTAAGGATTTTTCTCATATCCTAGCTCCAGCGAGTACGTTTGGTAAAAA
CCTAATGCCTCGTGTCGCTGCATTGCTGGATGTTGGGCAGCTGTCGGATGTGATTGCGATTGAATCGCCTGATACGGTTG
TTCGTCCAATCTATGCCGGTAATGCGTTAGCCAGAGTTCGCTCGGACGATGCTACCAAAGTGATGACGATTCGAAGCTCT
GCGTTTGACGCAATTGCTGTGTCTGATTCTCCAGTAGTTGAGAATGTCGCCACGTTAGAAACGGTAATTAAGGCAGAACA
CTGTGAGTTTGTTTCACAGCAGAAAGCGGAAAGTGAAAGACCAGAGCTACCGGCGGCGAACGTCGTTGTGTCCGGCGGTC
GTGGGTTGGGCAGCAAAGAGAGCTTTGCGCTGGTGGAACAACTTGCTGACAAGCTTGGTGGCGCTATTGGTGCGTCTCGC
GCTGCGGTAGATGCGGGTTTTGTGTCTAACGATTTGCAAGTTGGGCAGACAGGTAAGATTGTCGCGCCTCAGCTGTACAT
TGCTGTGGGTATTTCCGGTGCAATTCAACATTTAGCAGGGATGAAAGATTCCAAGGTGATTGTGGCGATCAACAGTGATC
CAGAAGCCCCAATCTTCCAAGTTGCAGACTATGGTTTAGTTGGCGACCTGTTTGAGATTATGCCGGAGTTGCTGGAGAAG
GTGTAA

Upstream 100 bases:

>100_bases
TGACACCGCCTGCACGAAAAGCGGGCGAAATGGTAGGCAGTGTGAGCGAGTTAGTCGACAAGCTCAAAAACGAAGCGAAA
GTGATTTAGGAGGCATAATC

Downstream 100 bases:

>100_bases
GTTCGATATTTTTCGGGCGTCATTTTGAGTTGCGAGGAACGTATATGGACTCCCCTAGTAATGCAAGAAGCTTAAGTTAG
CGGTTTACAAGTGCACGTAT

Product: acyl-CoA dehydrogenase, short-chain specific

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MENKPLATLVIVEHDNQSLSVDTLRALSAASDIQQDGTPLPVTALLIGHHCGSVLGELKCVQGISQIIVIDAAEYQHPLA
ENLSTLIADVGKDFSHILAPASTFGKNLMPRVAALLDVGQLSDVIAIESPDTVVRPIYAGNALARVRSDDATKVMTIRSS
AFDAIAVSDSPVVENVATLETVIKAEHCEFVSQQKAESERPELPAANVVVSGGRGLGSKESFALVEQLADKLGGAIGASR
AAVDAGFVSNDLQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINSDPEAPIFQVADYGLVGDLFEIMPELLEK
V

Sequences:

>Translated_321_residues
MENKPLATLVIVEHDNQSLSVDTLRALSAASDIQQDGTPLPVTALLIGHHCGSVLGELKCVQGISQIIVIDAAEYQHPLA
ENLSTLIADVGKDFSHILAPASTFGKNLMPRVAALLDVGQLSDVIAIESPDTVVRPIYAGNALARVRSDDATKVMTIRSS
AFDAIAVSDSPVVENVATLETVIKAEHCEFVSQQKAESERPELPAANVVVSGGRGLGSKESFALVEQLADKLGGAIGASR
AAVDAGFVSNDLQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINSDPEAPIFQVADYGLVGDLFEIMPELLEK
V
>Mature_321_residues
MENKPLATLVIVEHDNQSLSVDTLRALSAASDIQQDGTPLPVTALLIGHHCGSVLGELKCVQGISQIIVIDAAEYQHPLA
ENLSTLIADVGKDFSHILAPASTFGKNLMPRVAALLDVGQLSDVIAIESPDTVVRPIYAGNALARVRSDDATKVMTIRSS
AFDAIAVSDSPVVENVATLETVIKAEHCEFVSQQKAESERPELPAANVVVSGGRGLGSKESFALVEQLADKLGGAIGASR
AAVDAGFVSNDLQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINSDPEAPIFQVADYGLVGDLFEIMPELLEK
V

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=315, Percent_Identity=55.5555555555556, Blast_Score=322, Evalue=2e-88,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=58.7360594795539, Blast_Score=298, Evalue=4e-81,
Organism=Escherichia coli, GI1786226, Length=225, Percent_Identity=37.7777777777778, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787990, Length=270, Percent_Identity=30, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082157, Length=228, Percent_Identity=32.0175438596491, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=49.8402555910543, Blast_Score=291, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6325261, Length=291, Percent_Identity=46.3917525773196, Blast_Score=247, Evalue=2e-66,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=55.0314465408805, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=55.0314465408805, Blast_Score=317, Evalue=9e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33618; Mature: 33618

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKPLATLVIVEHDNQSLSVDTLRALSAASDIQQDGTPLPVTALLIGHHCGSVLGELKC
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VQGISQIIVIDAAEYQHPLAENLSTLIADVGKDFSHILAPASTFGKNLMPRVAALLDVGQ
HHCCHHEEEEECHHHCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSDVIAIESPDTVVRPIYAGNALARVRSDDATKVMTIRSSAFDAIAVSDSPVVENVATLE
CCCEEEECCCCCEECEECCCCHHHHHCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHH
TVIKAEHCEFVSQQKAESERPELPAANVVVSGGRGLGSKESFALVEQLADKLGGAIGASR
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHCCCH
AAVDAGFVSNDLQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINSDPEAPIFQ
HHHHCCCCCCCCEECCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
VADYGLVGDLFEIMPELLEKV
HHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENKPLATLVIVEHDNQSLSVDTLRALSAASDIQQDGTPLPVTALLIGHHCGSVLGELKC
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VQGISQIIVIDAAEYQHPLAENLSTLIADVGKDFSHILAPASTFGKNLMPRVAALLDVGQ
HHCCHHEEEEECHHHCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSDVIAIESPDTVVRPIYAGNALARVRSDDATKVMTIRSSAFDAIAVSDSPVVENVATLE
CCCEEEECCCCCEECEECCCCHHHHHCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHH
TVIKAEHCEFVSQQKAESERPELPAANVVVSGGRGLGSKESFALVEQLADKLGGAIGASR
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHCCCH
AAVDAGFVSNDLQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINSDPEAPIFQ
HHHHCCCCCCCCEECCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
VADYGLVGDLFEIMPELLEKV
HHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]