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The map label for this gene is yiaY [H]

Identifier: 156976638

GI number: 156976638

Start: 634761

End: 635909

Strand: Reverse

Name: yiaY [H]

Synonym: VIBHAR_05412

Alternate gene names: 156976638

Gene position: 635909-634761 (Counterclockwise)

Preceding gene: 156976639

Following gene: 156976637

Centisome position: 28.85

GC content: 47.35

Gene sequence:

>1149_bases
ATGACAAGTGCATTTTTTATCCCTACCGTAAACCTAATGGGCGCTGGTTGTTTGAAAGACGCCACAGACAGCATCCAATC
TCAAGGCTTTAAAAAAGGTTTGATTGTTACGGATAAGATTCTTAACCAAATCGGTGTAGTAAAGCAGGTTCAAGATCTAC
TGGCAGAACGCGACGTGGAAACCGTTGTATTCGATGGCACTCAACCAAACCCTACTATCAGCAACGTTAATGACGGCTTA
GCACTTCTTACTGATAACGAATGTGACTTCGTTATCTCTCTAGGCGGTGGTTCACCACACGACTGTGCGAAAGGTATCGC
ACTTGTTGCTTCTAACGGCGGCAAAATCGCAGATTACGAAGGCGTAGACCAGTCTGCAAAACCAATGATGCCACTTATCG
CAATCAACACGACTGCGGGTACTGCATCTGAAATGACGCGTTTCTGCATCATCACTGACGAAGAGCGTCACATCAAGATG
GCTATCGTTGATAAGCACACAACACCGCTTATCTCAGTAAACGATCCAGAGCTAATGCTAGCTAAGCCTGCTTCGCTAAC
CGCGGCAACAGGTATGGATGCCCTAACTCACGCGATTGAAGCTTACGTGTCTATCGCAGCAACACCAATCACTGATGCGG
TAGCAATCAAAGCAATTGAACTTATCCAAGCGTACCTACGCACAGCAGTGAAAAATGGTGAAGATCTAGAAGCTCGTGAG
CAAATGGCATACGCACAGTTCATGGCGGGTATGGCGTTCAACAACGCGTCTCTAGGTTACGTGCACGCAATGGCACACCA
ACTAGGTGGTTTCTACGACCTTCCACACGGTGTTTGTAACGCGATTCTTCTACCTCACGTACAGCGTTACAACGCGCAAG
TATGTCCAGAGCGCCTACGTGATGTAGCGAAAGCAATGGGCGTAAACGTAGAAGACATGTCTGCTGAAGCAGGTGCAGCG
GCAGCAATCGATGCTATCGTAACTCTAGCGAAAGATGTAGGCATTCCTGCAGGTATCAAGGAGCTTGGTGCGAAGCTAGA
AGACATCCCAACACTAGCAGACAACGCACTGAAAGACGCTTGTGGTTTCACTAACCCTAAACAAGCAACTCACGAAGAAA
TCTCTAAGATCTTCGAAGAAGCGATGTAA

Upstream 100 bases:

>100_bases
GGTAATCTTGTTCTAGATCAATCTCAACCAAGAATGGAGTATGCAAGAGTAAATGACAGATTAAGAAAGATTATTAAAAA
TAACGACGGAGCAATCCAAT

Downstream 100 bases:

>100_bases
TTTCGCTAACTAAACAATTCTCTATTGCCTTAATTCAATCCCCGATCTTGTATCGGGGATTTTTTACATTCTGATACTAC
TCATGCTCTGCCAAACGTTC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTSAFFIPTVNLMGAGCLKDATDSIQSQGFKKGLIVTDKILNQIGVVKQVQDLLAERDVETVVFDGTQPNPTISNVNDGL
ALLTDNECDFVISLGGGSPHDCAKGIALVASNGGKIADYEGVDQSAKPMMPLIAINTTAGTASEMTRFCIITDEERHIKM
AIVDKHTTPLISVNDPELMLAKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAIELIQAYLRTAVKNGEDLEARE
QMAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQRYNAQVCPERLRDVAKAMGVNVEDMSAEAGAA
AAIDAIVTLAKDVGIPAGIKELGAKLEDIPTLADNALKDACGFTNPKQATHEEISKIFEEAM

Sequences:

>Translated_382_residues
MTSAFFIPTVNLMGAGCLKDATDSIQSQGFKKGLIVTDKILNQIGVVKQVQDLLAERDVETVVFDGTQPNPTISNVNDGL
ALLTDNECDFVISLGGGSPHDCAKGIALVASNGGKIADYEGVDQSAKPMMPLIAINTTAGTASEMTRFCIITDEERHIKM
AIVDKHTTPLISVNDPELMLAKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAIELIQAYLRTAVKNGEDLEARE
QMAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQRYNAQVCPERLRDVAKAMGVNVEDMSAEAGAA
AAIDAIVTLAKDVGIPAGIKELGAKLEDIPTLADNALKDACGFTNPKQATHEEISKIFEEAM
>Mature_381_residues
TSAFFIPTVNLMGAGCLKDATDSIQSQGFKKGLIVTDKILNQIGVVKQVQDLLAERDVETVVFDGTQPNPTISNVNDGLA
LLTDNECDFVISLGGGSPHDCAKGIALVASNGGKIADYEGVDQSAKPMMPLIAINTTAGTASEMTRFCIITDEERHIKMA
IVDKHTTPLISVNDPELMLAKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAIELIQAYLRTAVKNGEDLEAREQ
MAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQRYNAQVCPERLRDVAKAMGVNVEDMSAEAGAAA
AIDAIVTLAKDVGIPAGIKELGAKLEDIPTLADNALKDACGFTNPKQATHEEISKIFEEAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=27.6283618581907, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=68.6842105263158, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=45.0520833333333, Blast_Score=341, Evalue=6e-95,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=37.1352785145889, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1787493, Length=407, Percent_Identity=32.6781326781327, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1789386, Length=323, Percent_Identity=25.6965944272446, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=410, Percent_Identity=26.8292682926829, Blast_Score=150, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6321181, Length=382, Percent_Identity=54.1884816753927, Blast_Score=419, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24657991, Length=411, Percent_Identity=29.4403892944039, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40458; Mature: 40327

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAFFIPTVNLMGAGCLKDATDSIQSQGFKKGLIVTDKILNQIGVVKQVQDLLAERDVE
CCCEEEECCHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCC
TVVFDGTQPNPTISNVNDGLALLTDNECDFVISLGGGSPHDCAKGIALVASNGGKIADYE
EEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHCCEEEEECCCCCCCCCC
GVDQSAKPMMPLIAINTTAGTASEMTRFCIITDEERHIKMAIVDKHTTPLISVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCCEEE
AKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAIELIQAYLRTAVKNGEDLEARE
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QMAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQRYNAQVCPERLR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHCCHHHHH
DVAKAMGVNVEDMSAEAGAAAAIDAIVTLAKDVGIPAGIKELGAKLEDIPTLADNALKDA
HHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHCCHHHHHHHHHH
CGFTNPKQATHEEISKIFEEAM
CCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSAFFIPTVNLMGAGCLKDATDSIQSQGFKKGLIVTDKILNQIGVVKQVQDLLAERDVE
CCEEEECCHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCC
TVVFDGTQPNPTISNVNDGLALLTDNECDFVISLGGGSPHDCAKGIALVASNGGKIADYE
EEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHCCEEEEECCCCCCCCCC
GVDQSAKPMMPLIAINTTAGTASEMTRFCIITDEERHIKMAIVDKHTTPLISVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCCEEE
AKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAIELIQAYLRTAVKNGEDLEARE
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QMAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQRYNAQVCPERLR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHCCHHHHH
DVAKAMGVNVEDMSAEAGAAAAIDAIVTLAKDVGIPAGIKELGAKLEDIPTLADNALKDA
HHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHCCHHHHHHHHHH
CGFTNPKQATHEEISKIFEEAM
CCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]