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The map label for this gene is atoB [H]

Identifier: 156976592

GI number: 156976592

Start: 595700

End: 596911

Strand: Direct

Name: atoB [H]

Synonym: VIBHAR_05366

Alternate gene names: 156976592

Gene position: 595700-596911 (Clockwise)

Preceding gene: 156976591

Following gene: 156976593

Centisome position: 27.03

GC content: 48.6

Gene sequence:

>1212_bases
ATGATGGAAAAAGTATTTATTGTTGCTGCGAAACGTACCCCAATTGGCGCATTTGGTGGAAGTCTAAAAAATACCTCAGC
AGGTAATCTTGCTGCGGTCGCGATTAAAGGCGCGCTTGAGGCTGCATCACTTTCTGCCGATAAGGTTGATGAAGTGATCG
TTGGTAACGTGATTGCTGCGGGCCAAGGCATGGGTGTTGGGCGCCAAGCAGCGTTGTTTGCTGGTATTCCAGAGTCAGTC
CCTGCATATGGCGTCAACATGGTTTGCGGCAGTGGTATGAAAACCGTCATGGATGGCGTTTCTCATATTCGCAGTGGCGA
TGCAGAAGTCGTTGTAGCAGCGGGCGTTGAGGTAATGTCGCAAATCCCATTCATCGTGCCAAGCGTTGTGCGCGACGGTA
ACAAAATGGGCAACATGGAGTTGAAAGATCTCCTTATTGCTGACGGTTTGACGGACGTTTACAACCGATATCATATGGGC
GTAACGGCAGAGAATGTGGCTAAGGAAATGGGTTTATCGCGTCAACAACAAGACGAATATGCACTCTCAAGCCAACAAAA
AGCGGTGGCAGCGATTGAAGCAGGCAAATTCAAAGACGAAATTGTTCCTGTAGAAGTCAAGCAACGTCGCGAAACTGTTG
TATTTGATACGGATGAATACCCAAAAGCAAACGCGACACTAGAAGGTTTGAGCAAGCTACGCCCTGCGTTTGACCGTGAA
GGTACAGTAACCGCAGGTAACGCTTCAGGCATAAACGACGGAGCAAGTGCCATCATTTTAGCATCAGAAAGCGCGGTTCA
AGCGCACGGCTTAACGCCAATTGCTGAAGTGGTGAGCTACGCTCAATCAGGTTTAGATCCTAAGGTTATGGGGCTTGGTC
CTGTGGAATCAGTCAACAAGGCGTTGCAAAAAGCCGAGCTGAAAACCAGCGACATTGATGTTTATGAATTGAATGAAGCC
TTTGCTGCGCAAGCGCTAGGTGTGATTCATAAACTGGCAGAAACCAACCAAGTACCAGTGAGCTCAATTCAAGATAAGGC
CAACTTTAATGGTGGCGCTATCGCGTTGGGTCACCCACTCGGTGCGTCGGGTAACCGTATTCTGGTTACGCTAGTACACG
AACTTCACAAACAAGACGGTCAATACGGTGTTGCTTCACTTTGTGTGGGCGGCGGTATGGGCACGGCTGTGGTTGTAAAA
GCAGTTAAATAG

Upstream 100 bases:

>100_bases
TGCTGCATCAGTGAGCTTTTTAGTAAGTGATGCAGGCGCGTACATCACCGGCGAAACATTGTCGGTGAATGGCGGCCTAT
ACATGCACTAAGGAGTATTG

Downstream 100 bases:

>100_bases
TTATTTAAACGGAAATTTTTAATTCTTTCTCTAGGAGATAAACCATGTACACTGATTTCTTCAAACCTTTTAGCGATCAA
ACTGAAAAGAATCTAGAACC

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MMEKVFIVAAKRTPIGAFGGSLKNTSAGNLAAVAIKGALEAASLSADKVDEVIVGNVIAAGQGMGVGRQAALFAGIPESV
PAYGVNMVCGSGMKTVMDGVSHIRSGDAEVVVAAGVEVMSQIPFIVPSVVRDGNKMGNMELKDLLIADGLTDVYNRYHMG
VTAENVAKEMGLSRQQQDEYALSSQQKAVAAIEAGKFKDEIVPVEVKQRRETVVFDTDEYPKANATLEGLSKLRPAFDRE
GTVTAGNASGINDGASAIILASESAVQAHGLTPIAEVVSYAQSGLDPKVMGLGPVESVNKALQKAELKTSDIDVYELNEA
FAAQALGVIHKLAETNQVPVSSIQDKANFNGGAIALGHPLGASGNRILVTLVHELHKQDGQYGVASLCVGGGMGTAVVVK
AVK

Sequences:

>Translated_403_residues
MMEKVFIVAAKRTPIGAFGGSLKNTSAGNLAAVAIKGALEAASLSADKVDEVIVGNVIAAGQGMGVGRQAALFAGIPESV
PAYGVNMVCGSGMKTVMDGVSHIRSGDAEVVVAAGVEVMSQIPFIVPSVVRDGNKMGNMELKDLLIADGLTDVYNRYHMG
VTAENVAKEMGLSRQQQDEYALSSQQKAVAAIEAGKFKDEIVPVEVKQRRETVVFDTDEYPKANATLEGLSKLRPAFDRE
GTVTAGNASGINDGASAIILASESAVQAHGLTPIAEVVSYAQSGLDPKVMGLGPVESVNKALQKAELKTSDIDVYELNEA
FAAQALGVIHKLAETNQVPVSSIQDKANFNGGAIALGHPLGASGNRILVTLVHELHKQDGQYGVASLCVGGGMGTAVVVK
AVK
>Mature_403_residues
MMEKVFIVAAKRTPIGAFGGSLKNTSAGNLAAVAIKGALEAASLSADKVDEVIVGNVIAAGQGMGVGRQAALFAGIPESV
PAYGVNMVCGSGMKTVMDGVSHIRSGDAEVVVAAGVEVMSQIPFIVPSVVRDGNKMGNMELKDLLIADGLTDVYNRYHMG
VTAENVAKEMGLSRQQQDEYALSSQQKAVAAIEAGKFKDEIVPVEVKQRRETVVFDTDEYPKANATLEGLSKLRPAFDRE
GTVTAGNASGINDGASAIILASESAVQAHGLTPIAEVVSYAQSGLDPKVMGLGPVESVNKALQKAELKTSDIDVYELNEA
FAAQALGVIHKLAETNQVPVSSIQDKANFNGGAIALGHPLGASGNRILVTLVHELHKQDGQYGVASLCVGGGMGTAVVVK
AVK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=400, Percent_Identity=46.5, Blast_Score=360, Evalue=2e-99,
Organism=Homo sapiens, GI167614485, Length=404, Percent_Identity=46.7821782178218, Blast_Score=356, Evalue=2e-98,
Organism=Homo sapiens, GI4557237, Length=402, Percent_Identity=41.2935323383085, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI4501853, Length=403, Percent_Identity=39.2059553349876, Blast_Score=265, Evalue=5e-71,
Organism=Homo sapiens, GI4504327, Length=427, Percent_Identity=34.6604215456674, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI194353979, Length=398, Percent_Identity=29.8994974874372, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1788554, Length=399, Percent_Identity=52.3809523809524, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI87082165, Length=399, Percent_Identity=48.6215538847118, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787663, Length=407, Percent_Identity=40.7862407862408, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI48994986, Length=417, Percent_Identity=40.7673860911271, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1788683, Length=410, Percent_Identity=30.2439024390244, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI133906874, Length=400, Percent_Identity=45.75, Blast_Score=342, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI25147385, Length=396, Percent_Identity=40.1515151515151, Blast_Score=290, Evalue=9e-79,
Organism=Caenorhabditis elegans, GI17535921, Length=401, Percent_Identity=41.3965087281795, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17551802, Length=434, Percent_Identity=32.4884792626728, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17535917, Length=398, Percent_Identity=31.6582914572864, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6325229, Length=409, Percent_Identity=41.8092909535452, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6322031, Length=412, Percent_Identity=37.8640776699029, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24655093, Length=399, Percent_Identity=51.8796992481203, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI17648125, Length=401, Percent_Identity=45.8852867830424, Blast_Score=320, Evalue=9e-88,
Organism=Drosophila melanogaster, GI24640423, Length=400, Percent_Identity=41.5, Blast_Score=303, Evalue=9e-83,
Organism=Drosophila melanogaster, GI17137578, Length=430, Percent_Identity=31.6279069767442, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41754; Mature: 41754

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKVFIVAAKRTPIGAFGGSLKNTSAGNLAAVAIKGALEAASLSADKVDEVIVGNVIAA
CCCEEEEEEECCCCCHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHCCCEEC
GQGMGVGRQAALFAGIPESVPAYGVNMVCGSGMKTVMDGVSHIRSGDAEVVVAAGVEVMS
CCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHH
QIPFIVPSVVRDGNKMGNMELKDLLIADGLTDVYNRYHMGVTAENVAKEMGLSRQQQDEY
HCCHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
ALSSQQKAVAAIEAGKFKDEIVPVEVKQRRETVVFDTDEYPKANATLEGLSKLRPAFDRE
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCC
GTVTAGNASGINDGASAIILASESAVQAHGLTPIAEVVSYAQSGLDPKVMGLGPVESVNK
CCEEECCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHH
ALQKAELKTSDIDVYELNEAFAAQALGVIHKLAETNQVPVSSIQDKANFNGGAIALGHPL
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECCCC
GASGNRILVTLVHELHKQDGQYGVASLCVGGGMGTAVVVKAVK
CCCCCEEEHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MMEKVFIVAAKRTPIGAFGGSLKNTSAGNLAAVAIKGALEAASLSADKVDEVIVGNVIAA
CCCEEEEEEECCCCCHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHCCCEEC
GQGMGVGRQAALFAGIPESVPAYGVNMVCGSGMKTVMDGVSHIRSGDAEVVVAAGVEVMS
CCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHH
QIPFIVPSVVRDGNKMGNMELKDLLIADGLTDVYNRYHMGVTAENVAKEMGLSRQQQDEY
HCCHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
ALSSQQKAVAAIEAGKFKDEIVPVEVKQRRETVVFDTDEYPKANATLEGLSKLRPAFDRE
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCC
GTVTAGNASGINDGASAIILASESAVQAHGLTPIAEVVSYAQSGLDPKVMGLGPVESVNK
CCEEECCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHH
ALQKAELKTSDIDVYELNEAFAAQALGVIHKLAETNQVPVSSIQDKANFNGGAIALGHPL
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECCCC
GASGNRILVTLVHELHKQDGQYGVASLCVGGGMGTAVVVKAVK
CCCCCEEEHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]