BacMap

Definition	Vibrio harveyi ATCC BAA-1116 chromosome II, complete sequence.
Accession	NC_009784
Length	2,204,018

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The map label for this gene is phaB [H]

Identifier: 156976591

GI number: 156976591

Start: 594884

End: 595690

Strand: Direct

Name: phaB [H]

Synonym: VIBHAR_05365

Alternate gene names: 156976591

Gene position: 594884-595690 (Clockwise)

Preceding gene: 156976588

Following gene: 156976592

Centisome position: 26.99

GC content: 45.23

Gene sequence:

>807_bases
TTGGCGAAGAATTTCGCCAGTGTCTTAATTCGCTTTTTTAATGCCGTTAAGAATGGAGTCTTTTTAATGAAGAAAGTCGC
TTTGATCACCGGATCAAAAGGCGGAATTGGTTCTGCAATTTCCTCTCAACTAGTGAATGATGGTTACCGCGTTATTGCAA
CGTATTTTACTGGTAAATATGAGTGTGCTTTGGAATGGTTTAATGAAAAAGGGTTTACCAAAGATCAGGTTCGCCTTTTT
GAATTAGACGTGACCGACACCGCTCAGTGTGCTGAGAAATTGGCACTTATCCTCGAGGAAGAAGGGACAATAGACGTCGT
TATCAACAACGCAGGTATTACACGTGATGGCGTGTTCAAAAAGATGACTGCTCAAGCTTGGAACGACGTGATCAATACCA
ACTTAAATAGCTTGTTCAATGTGACGCAGCCACTTTTCGCAGCCATGTGTGAAAAAGGTGGTGGTCGCATCATCAATATC
TCTTCTGTGAATGGTCTGAAAGGGCAGTTTGGGCAAGCAAACTACTCGGCAGCAAAAGCTGGCATGATTGGATTCTCCAA
AGCATTAGCCTACGAGGGCGCACGCTCAGGCGTCACAGTAAATGTTATTGCCCCGGGATACACAGGCACTCCAATGGTTG
AGCAGATGAAACCAGAAGTGCTTGAGTCGATCACGAGTCAAATTCCAATGAAGCGTCTGGCGACGCCAGAAGAAATTGCT
GCATCAGTGAGCTTTTTAGTAAGTGATGCAGGCGCGTACATCACCGGCGAAACATTGTCGGTGAATGGCGGCCTATACAT
GCACTAA

Upstream 100 bases:

>100_bases
AAATGATTTGGTTTTTTATTTGAAATGTAACAATTCTAGGTTAACTTAAAAATAAAGGCGGCAGAGGATTTGTTGCCACA
AGAATATATTAACACGTCAG

Downstream 100 bases:

>100_bases
GGAGTATTGATGATGGAAAAAGTATTTATTGTTGCTGCGAAACGTACCCCAATTGGCGCATTTGGTGGAAGTCTAAAAAA
TACCTCAGCAGGTAATCTTG

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAKNFASVLIRFFNAVKNGVFLMKKVALITGSKGGIGSAISSQLVNDGYRVIATYFTGKYECALEWFNEKGFTKDQVRLF
ELDVTDTAQCAEKLALILEEEGTIDVVINNAGITRDGVFKKMTAQAWNDVINTNLNSLFNVTQPLFAAMCEKGGGRIINI
SSVNGLKGQFGQANYSAAKAGMIGFSKALAYEGARSGVTVNVIAPGYTGTPMVEQMKPEVLESITSQIPMKRLATPEEIA
ASVSFLVSDAGAYITGETLSVNGGLYMH

Sequences:

>Translated_268_residues
MAKNFASVLIRFFNAVKNGVFLMKKVALITGSKGGIGSAISSQLVNDGYRVIATYFTGKYECALEWFNEKGFTKDQVRLF
ELDVTDTAQCAEKLALILEEEGTIDVVINNAGITRDGVFKKMTAQAWNDVINTNLNSLFNVTQPLFAAMCEKGGGRIINI
SSVNGLKGQFGQANYSAAKAGMIGFSKALAYEGARSGVTVNVIAPGYTGTPMVEQMKPEVLESITSQIPMKRLATPEEIA
ASVSFLVSDAGAYITGETLSVNGGLYMH
>Mature_267_residues
AKNFASVLIRFFNAVKNGVFLMKKVALITGSKGGIGSAISSQLVNDGYRVIATYFTGKYECALEWFNEKGFTKDQVRLFE
LDVTDTAQCAEKLALILEEEGTIDVVINNAGITRDGVFKKMTAQAWNDVINTNLNSLFNVTQPLFAAMCEKGGGRIINIS
SVNGLKGQFGQANYSAAKAGMIGFSKALAYEGARSGVTVNVIAPGYTGTPMVEQMKPEVLESITSQIPMKRLATPEEIAA
SVSFLVSDAGAYITGETLSVNGGLYMH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=36.5758754863813, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=35.8870967741936, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.496062992126, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI4504505, Length=249, Percent_Identity=31.7269076305221, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=31.7829457364341, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=29.4820717131474, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.6, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=30, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=29.5, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=30.1158301158301, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=25.78125, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=190, Percent_Identity=32.1052631578947, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=25.1063829787234, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI150247226, Length=206, Percent_Identity=31.5533980582524, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=28.1553398058252, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7657478, Length=205, Percent_Identity=28.2926829268293, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19743808, Length=218, Percent_Identity=28.4403669724771, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503301, Length=196, Percent_Identity=27.0408163265306, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=27.810650887574, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40548397, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22507405, Length=240, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=26.7015706806283, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=46.7479674796748, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=35.7142857142857, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=30.46875, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=32.421875, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=30.7086614173228, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=29.7297297297297, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=29.7959183673469, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.8387096774194, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.0813008130081, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787820, Length=238, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=26.1410788381743, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=26.953125, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25.3846153846154, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=30.2702702702703, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=39.3574297188755, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=39.3574297188755, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=31.2741312741313, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.4, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=235, Percent_Identity=30.2127659574468, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=28.3464566929134, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=30.3846153846154, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=29.8850574712644, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=27.734375, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.277566539924, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.0676691729323, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=27.5193798449612, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=27.6264591439689, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.3524904214559, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=27.6264591439689, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=217, Percent_Identity=26.2672811059908, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=25.7425742574257, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=27.2373540856031, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=26.2548262548263, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=225, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=26.953125, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=209, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=209, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=25.3787878787879, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=25.5905511811024, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=25.6603773584906, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=27.4809160305344, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=237, Percent_Identity=31.2236286919831, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=28.8617886178862, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=28.7179487179487, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=38.0566801619433, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.3149606299213, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859837, Length=238, Percent_Identity=31.9327731092437, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=29.8804780876494, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=29.3172690763052, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=28.1632653061224, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=30.8880308880309, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644337, Length=172, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581726, Length=162, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24665243, Length=205, Percent_Identity=30.7317073170732, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24665247, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356301, Length=216, Percent_Identity=26.8518518518519, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=236, Percent_Identity=25.8474576271186, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24665264, Length=206, Percent_Identity=30.5825242718447, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24656154, Length=262, Percent_Identity=29.3893129770992, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922628, Length=262, Percent_Identity=29.3893129770992, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 28743; Mature: 28612

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNFASVLIRFFNAVKNGVFLMKKVALITGSKGGIGSAISSQLVNDGYRVIATYFTGKY
CCCHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHHHCCCCEEEEEEECCCE
ECALEWFNEKGFTKDQVRLFELDVTDTAQCAEKLALILEEEGTIDVVINNAGITRDGVFK
EEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
KMTAQAWNDVINTNLNSLFNVTQPLFAAMCEKGGGRIINISSVNGLKGQFGQANYSAAKA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHH
GMIGFSKALAYEGARSGVTVNVIAPGYTGTPMVEQMKPEVLESITSQIPMKRLATPEEIA
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHCCHHHHHHHHHHCCHHHCCCHHHHH
ASVSFLVSDAGAYITGETLSVNGGLYMH
HHHHHHHHCCCCEEECCEEEECCCEEEC
>Mature Secondary Structure 
AKNFASVLIRFFNAVKNGVFLMKKVALITGSKGGIGSAISSQLVNDGYRVIATYFTGKY
CCHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHHHCCCCEEEEEEECCCE
ECALEWFNEKGFTKDQVRLFELDVTDTAQCAEKLALILEEEGTIDVVINNAGITRDGVFK
EEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
KMTAQAWNDVINTNLNSLFNVTQPLFAAMCEKGGGRIINISSVNGLKGQFGQANYSAAKA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHH
GMIGFSKALAYEGARSGVTVNVIAPGYTGTPMVEQMKPEVLESITSQIPMKRLATPEEIA
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHCCHHHHHHHHHHCCHHHCCCHHHHH
ASVSFLVSDAGAYITGETLSVNGGLYMH
HHHHHHHHCCCCEEECCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7635832 [H]