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The map label for this gene is yycF [H]

Identifier: 156976557

GI number: 156976557

Start: 563584

End: 564426

Strand: Direct

Name: yycF [H]

Synonym: VIBHAR_05331

Alternate gene names: 156976557

Gene position: 563584-564426 (Clockwise)

Preceding gene: 156976556

Following gene: 156976558

Centisome position: 25.57

GC content: 41.87

Gene sequence:

>843_bases
GTGTTTTTTTGTAGAGAGCGCTTTTTTATAAATGTATGGTTTGTAAGTGTTTGTAAGCACTTTCTGTCGCTAGAGGTTCG
GTTTATATGGGTTGCATGGAACAAAACGAGCGATATACTGCCTCTGTTTTATAGGTTGGGTGAATGGATTATGGTCGGTA
ATAAAATTTTGCTCGTAGAGGACGATTCAGAGATTGCTCGATTAACCAAAATGTACCTAGAGGCTGAAGGTTACCTAGTT
ACTGTTCTCGACAATGGTCTTAATGCACTCGACGCTATCAAAGAATTGAAGCCTGATCTGGTGTTATTGGATTTGATGCT
CCCAGGCAAAAATGGTGCAGAGATATGCCAAGAGGCTAGGGCATTTTATCATGGAATAATCATTGTGTTGACGGCCACTG
ATGATGAGATGAGTGAAGTTAGCCTATTTAAATTTGGTGCTGATGATTACCTAACGAAACCAATTAAGGGCAATATCCTC
CTCGCTCGTATTGAGGCCTCTTTACGCCGTTACCGTCGCCAAATAGATTCGGATGAAAAGACAGAGCTGAGCCGTTATGG
CATCGACTTATGCACCCGTCGCTCTAAAGCTTATTACTTAGAGCAAGATATCGATCTCACTGATTCTGAGTTCGAAATAT
TGGAGCTATTAATGCTCAATGTTGATAAACCCGTTTCTCGAGAGTCCTGTTGCCGCCTTGCGCGTGGCATTGAATACTGC
ATTACTGACCGTTCAATTGATATGCGAATCTCTTCTTTGAGGAAAAAATTCTCAAAAGCCCTTATTCACACCGCTACCAT
TAAGACCGTGCGTAATCGTGGATACATGTTAACGGGGAAATAG

Upstream 100 bases:

>100_bases
TCGACAAAGCTAAAATAATAGTAGCTTTATATTTTGTTTTTGGTTTAATTGATGATATTAAATCTTAACTTGTTTTTATA
AATTGGTTTTTTGTTCTTTT

Downstream 100 bases:

>100_bases
CGGATGTTCTCTCTGTTTACTCGGCTCTATGTTGGATTGGTAACGGGCCTTGCAGTGACTGTCGCCTTGTTTTTTACTAT
GGGTGACGAGTTTATGCGCA

Product: transcriptional regulatory protein CpxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MFFCRERFFINVWFVSVCKHFLSLEVRFIWVAWNKTSDILPLFYRLGEWIMVGNKILLVEDDSEIARLTKMYLEAEGYLV
TVLDNGLNALDAIKELKPDLVLLDLMLPGKNGAEICQEARAFYHGIIIVLTATDDEMSEVSLFKFGADDYLTKPIKGNIL
LARIEASLRRYRRQIDSDEKTELSRYGIDLCTRRSKAYYLEQDIDLTDSEFEILELLMLNVDKPVSRESCCRLARGIEYC
ITDRSIDMRISSLRKKFSKALIHTATIKTVRNRGYMLTGK

Sequences:

>Translated_280_residues
MFFCRERFFINVWFVSVCKHFLSLEVRFIWVAWNKTSDILPLFYRLGEWIMVGNKILLVEDDSEIARLTKMYLEAEGYLV
TVLDNGLNALDAIKELKPDLVLLDLMLPGKNGAEICQEARAFYHGIIIVLTATDDEMSEVSLFKFGADDYLTKPIKGNIL
LARIEASLRRYRRQIDSDEKTELSRYGIDLCTRRSKAYYLEQDIDLTDSEFEILELLMLNVDKPVSRESCCRLARGIEYC
ITDRSIDMRISSLRKKFSKALIHTATIKTVRNRGYMLTGK
>Mature_280_residues
MFFCRERFFINVWFVSVCKHFLSLEVRFIWVAWNKTSDILPLFYRLGEWIMVGNKILLVEDDSEIARLTKMYLEAEGYLV
TVLDNGLNALDAIKELKPDLVLLDLMLPGKNGAEICQEARAFYHGIIIVLTATDDEMSEVSLFKFGADDYLTKPIKGNIL
LARIEASLRRYRRQIDSDEKTELSRYGIDLCTRRSKAYYLEQDIDLTDSEFEILELLMLNVDKPVSRESCCRLARGIEYC
ITDRSIDMRISSLRKKFSKALIHTATIKTVRNRGYMLTGK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=33.9130434782609, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=38.5964912280702, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.9366515837104, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=36.480686695279, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=30.1724137931034, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=28.2608695652174, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786911, Length=206, Percent_Identity=29.126213592233, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=31.2775330396476, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=29.8319327731092, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=31.4159292035398, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=30.4721030042918, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.1479820627803, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=30, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 32472; Mature: 32472

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFCRERFFINVWFVSVCKHFLSLEVRFIWVAWNKTSDILPLFYRLGEWIMVGNKILLVE
CCEECCHHEEHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHCCEEEECCEEEEEE
DDSEIARLTKMYLEAEGYLVTVLDNGLNALDAIKELKPDLVLLDLMLPGKNGAEICQEAR
CCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHH
AFYHGIIIVLTATDDEMSEVSLFKFGADDYLTKPIKGNILLARIEASLRRYRRQIDSDEK
HHHCEEEEEEEECCCCHHHEEEEEECCHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCHH
TELSRYGIDLCTRRSKAYYLEQDIDLTDSEFEILELLMLNVDKPVSRESCCRLARGIEYC
HHHHHHCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
ITDRSIDMRISSLRKKFSKALIHTATIKTVRNRGYMLTGK
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MFFCRERFFINVWFVSVCKHFLSLEVRFIWVAWNKTSDILPLFYRLGEWIMVGNKILLVE
CCEECCHHEEHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHCCEEEECCEEEEEE
DDSEIARLTKMYLEAEGYLVTVLDNGLNALDAIKELKPDLVLLDLMLPGKNGAEICQEAR
CCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHH
AFYHGIIIVLTATDDEMSEVSLFKFGADDYLTKPIKGNILLARIEASLRRYRRQIDSDEK
HHHCEEEEEEEECCCCHHHEEEEEECCHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCHH
TELSRYGIDLCTRRSKAYYLEQDIDLTDSEFEILELLMLNVDKPVSRESCCRLARGIEYC
HHHHHHCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
ITDRSIDMRISSLRKKFSKALIHTATIKTVRNRGYMLTGK
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]