Click here to switch to the map view.

The map label for this gene is fruA [H]

Identifier: 156976411

GI number: 156976411

Start: 440061

End: 441968

Strand: Reverse

Name: fruA [H]

Synonym: VIBHAR_05184

Alternate gene names: 156976411

Gene position: 441968-440061 (Counterclockwise)

Preceding gene: 156976413

Following gene: 156976410

Centisome position: 20.05

GC content: 49.0

Gene sequence:

>1908_bases
ATGATCACCAAACTAATAAATGAAGACTTGATTAAGCTTGATCTTCAAGCGACTTCAAAAGAAGACGTATTTAAAGAACT
GGTTGCAGTTCTACACGCCCAAGGTCGTATTTCAGACCAAGAGCAATTTCTTGCAGATATAAAAGCACGTGAAGAATTAG
GTAATACCGGATTTGAAGATGGCGTAGCTATCCCACACGCAAAAAGTGCAGCAGTCATCGAACCAGCGGTTGTGATCGGC
GTAAGCAAATCAGGTATCGAATACGGCGCGGAAGACGGTTTGCCTTCAAAACTGTTCTTCATGATCGCTTCTCCAGACGG
TGGCGATAACCACCACATCGAAGTACTTGCAGAGCTGTCTTCAAAATTAATTGAAGATGGTTTCATTGATGCGTTTTTAG
GTGCAACAAACAGCCAAGACGCACTGGCACTCGTGCTTGCTAAAGAAGAGCCACAACCAGTGGCAGACGCTCCAACAAAC
CAAGGCTTCATCATTGGTGTTACCGGTTGTCCTGCAGGCGTTGCACACACTTACCTAGCGGCAGAAGCGCTTGAGAAAGG
TGCAGCAGCGATGGGGTACGAAATCAAGGTTGAAACGAATGGTTCAATCGGTGTGAAAAACAGCCCAACCGCAGAAGAAA
TCGAACGTGCAGACGCAATCATTGTGGCATGTGACAAACAAGTCAACATGAACCGCTTTGCGGGCAAACGCGTGGTTAAA
ACTAACGTAAAAGCCCCTATCCGCGATGCTCAAGGTCTGATTAACGAAGCGTTAAGCGCTCCAGAATACCAAGCAGAAGC
AAGCAGCAATGCGCAAACTTCTGTTGCAAACAAGGCCTCTCAGGCTCGCTCTGACCTATACCGCTACTTGATGAACGGCG
TATCACACATGATCCCATTCGTTGTAACGGGTGGTCTGTTGATTGCACTTGCTCTTGCAGTTGGTGGGCAGCCAAGTGAA
GCCGGTATGGCAATTCCTGAAGGCAGCATGTGGAACCAAATCCTCAACGTAGGTGTGGTTGCCTTTACGCTGATGATTCC
AATCCTAGCCGGTTACATTGCCTACGCGATTGCTGACCGCCCTGCTCTAGCTCCTGGTTTGATCGGTGGTTGGATTGCAA
ACAACGGTTCTTTCTACGGCGCAGACGCAGGTACAGGCTTTATCGGTGCCATCATCGCTGGTCTGCTTGTGGGTTACTTC
GTGAAGTGGATTACGTCGATTAACTACCACAAATTCATTCAACCTTTGGTGCCAATCATGATTGCGCCAATCACAGGTTC
GCTATTCATCGCTGGTCTTTTCATCTTCGTTATCGGCGCGCCAATCGCAAGCCTAATGGACGGTCTGACTGCGCTACTAA
CAAGCATGAGTACAGGTAACGTCGTTCTACTAGGCATCGTACTTGGTGGTATGGCTGGCTTCGATATGGGTGGTCCATTC
AACAAGGTCGCGTTCCTATTCTCTGTAGGCATGATTGCGAGTGGTCAAACTCAATTTATGGGTGCGATGGCGTGTGCAAT
CCCTGTTGCACCTCTAGGCATGGCACTGGCAACGGCACTGGGTCGTAAGTTCGACCTGTTCGAAGAATCAGAAACCGAAG
CGGGTAAAGCAGCAGGCGCAATGGGTCTAGTTGGTATCTCTGAAGGTGCGATTCCGTTCGCAGCGCAAGATCCAATGTCA
GTGATTCCAGCAAACGTACTTGGCTCAATGGTAGCGGCAGTAATGGCGTTCTCATTCGGCATTACCAACAGTGTTGCTCA
CGGCGGTCCAGTTGTCGCTCTACTTGGCGCGATGAACCACCCAGTACTTGCTCTGATTTGTATGGCAGCTGGCGCAGTGG
TTACCGCAGTAACGTGTGTAACTCTGAAGAAAGTTCGCAAAGCAAAAATGATGCAAGCAGCCGCTTAA

Upstream 100 bases:

>100_bases
TACAATCGTCCAGTAAATGCATTTTTTCTTCACTACTGTCTCCGCTTGGTTAATTTCAAAATACCCCTGAAATAAAAATT
ATATTTATAGGGGTTCGACA

Downstream 100 bases:

>100_bases
TCACCCCTACCCCCAATGGCTCCTATGGCTTGGGCAATGTCGCCCAAGCCATAATTTTCTCTCATGGTGACACTCTATGT
CTGATTTAACGATATCCGAT

Product: PTS system fructose-specific IIABC component

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MITKLINEDLIKLDLQATSKEDVFKELVAVLHAQGRISDQEQFLADIKAREELGNTGFEDGVAIPHAKSAAVIEPAVVIG
VSKSGIEYGAEDGLPSKLFFMIASPDGGDNHHIEVLAELSSKLIEDGFIDAFLGATNSQDALALVLAKEEPQPVADAPTN
QGFIIGVTGCPAGVAHTYLAAEALEKGAAAMGYEIKVETNGSIGVKNSPTAEEIERADAIIVACDKQVNMNRFAGKRVVK
TNVKAPIRDAQGLINEALSAPEYQAEASSNAQTSVANKASQARSDLYRYLMNGVSHMIPFVVTGGLLIALALAVGGQPSE
AGMAIPEGSMWNQILNVGVVAFTLMIPILAGYIAYAIADRPALAPGLIGGWIANNGSFYGADAGTGFIGAIIAGLLVGYF
VKWITSINYHKFIQPLVPIMIAPITGSLFIAGLFIFVIGAPIASLMDGLTALLTSMSTGNVVLLGIVLGGMAGFDMGGPF
NKVAFLFSVGMIASGQTQFMGAMACAIPVAPLGMALATALGRKFDLFEESETEAGKAAGAMGLVGISEGAIPFAAQDPMS
VIPANVLGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNHPVLALICMAAGAVVTAVTCVTLKKVRKAKMMQAAA

Sequences:

>Translated_635_residues
MITKLINEDLIKLDLQATSKEDVFKELVAVLHAQGRISDQEQFLADIKAREELGNTGFEDGVAIPHAKSAAVIEPAVVIG
VSKSGIEYGAEDGLPSKLFFMIASPDGGDNHHIEVLAELSSKLIEDGFIDAFLGATNSQDALALVLAKEEPQPVADAPTN
QGFIIGVTGCPAGVAHTYLAAEALEKGAAAMGYEIKVETNGSIGVKNSPTAEEIERADAIIVACDKQVNMNRFAGKRVVK
TNVKAPIRDAQGLINEALSAPEYQAEASSNAQTSVANKASQARSDLYRYLMNGVSHMIPFVVTGGLLIALALAVGGQPSE
AGMAIPEGSMWNQILNVGVVAFTLMIPILAGYIAYAIADRPALAPGLIGGWIANNGSFYGADAGTGFIGAIIAGLLVGYF
VKWITSINYHKFIQPLVPIMIAPITGSLFIAGLFIFVIGAPIASLMDGLTALLTSMSTGNVVLLGIVLGGMAGFDMGGPF
NKVAFLFSVGMIASGQTQFMGAMACAIPVAPLGMALATALGRKFDLFEESETEAGKAAGAMGLVGISEGAIPFAAQDPMS
VIPANVLGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNHPVLALICMAAGAVVTAVTCVTLKKVRKAKMMQAAA
>Mature_635_residues
MITKLINEDLIKLDLQATSKEDVFKELVAVLHAQGRISDQEQFLADIKAREELGNTGFEDGVAIPHAKSAAVIEPAVVIG
VSKSGIEYGAEDGLPSKLFFMIASPDGGDNHHIEVLAELSSKLIEDGFIDAFLGATNSQDALALVLAKEEPQPVADAPTN
QGFIIGVTGCPAGVAHTYLAAEALEKGAAAMGYEIKVETNGSIGVKNSPTAEEIERADAIIVACDKQVNMNRFAGKRVVK
TNVKAPIRDAQGLINEALSAPEYQAEASSNAQTSVANKASQARSDLYRYLMNGVSHMIPFVVTGGLLIALALAVGGQPSE
AGMAIPEGSMWNQILNVGVVAFTLMIPILAGYIAYAIADRPALAPGLIGGWIANNGSFYGADAGTGFIGAIIAGLLVGYF
VKWITSINYHKFIQPLVPIMIAPITGSLFIAGLFIFVIGAPIASLMDGLTALLTSMSTGNVVLLGIVLGGMAGFDMGGPF
NKVAFLFSVGMIASGQTQFMGAMACAIPVAPLGMALATALGRKFDLFEESETEAGKAAGAMGLVGISEGAIPFAAQDPMS
VIPANVLGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNHPVLALICMAAGAVVTAVTCVTLKKVRKAKMMQAAA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=465, Percent_Identity=41.7204301075269, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1786951, Length=592, Percent_Identity=34.4594594594595, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI87082348, Length=477, Percent_Identity=33.9622641509434, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1790386, Length=319, Percent_Identity=42.9467084639498, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1788729, Length=410, Percent_Identity=27.5609756097561, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790387, Length=94, Percent_Identity=48.936170212766, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI2367327, Length=135, Percent_Identity=31.8518518518519, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788730, Length=95, Percent_Identity=41.0526315789474, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790390, Length=105, Percent_Identity=35.2380952380952, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 65612; Mature: 65612

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKLINEDLIKLDLQATSKEDVFKELVAVLHAQGRISDQEQFLADIKAREELGNTGFED
CCHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
GVAIPHAKSAAVIEPAVVIGVSKSGIEYGAEDGLPSKLFFMIASPDGGDNHHIEVLAELS
CCCCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHH
SKLIEDGFIDAFLGATNSQDALALVLAKEEPQPVADAPTNQGFIIGVTGCPAGVAHTYLA
HHHHHCCCHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
AEALEKGAAAMGYEIKVETNGSIGVKNSPTAEEIERADAIIVACDKQVNMNRFAGKRVVK
HHHHHCCCHHCCEEEEEECCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCHHHHCCHHEE
TNVKAPIRDAQGLINEALSAPEYQAEASSNAQTSVANKASQARSDLYRYLMNGVSHMIPF
CCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVTGGLLIALALAVGGQPSEAGMAIPEGSMWNQILNVGVVAFTLMIPILAGYIAYAIADR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALAPGLIGGWIANNGSFYGADAGTGFIGAIIAGLLVGYFVKWITSINYHKFIQPLVPIM
CCCCCCHHHCEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAPITGSLFIAGLFIFVIGAPIASLMDGLTALLTSMSTGNVVLLGIVLGGMAGFDMGGPF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCH
NKVAFLFSVGMIASGQTQFMGAMACAIPVAPLGMALATALGRKFDLFEESETEAGKAAGA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
MGLVGISEGAIPFAAQDPMSVIPANVLGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNH
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
PVLALICMAAGAVVTAVTCVTLKKVRKAKMMQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITKLINEDLIKLDLQATSKEDVFKELVAVLHAQGRISDQEQFLADIKAREELGNTGFED
CCHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
GVAIPHAKSAAVIEPAVVIGVSKSGIEYGAEDGLPSKLFFMIASPDGGDNHHIEVLAELS
CCCCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHH
SKLIEDGFIDAFLGATNSQDALALVLAKEEPQPVADAPTNQGFIIGVTGCPAGVAHTYLA
HHHHHCCCHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
AEALEKGAAAMGYEIKVETNGSIGVKNSPTAEEIERADAIIVACDKQVNMNRFAGKRVVK
HHHHHCCCHHCCEEEEEECCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCHHHHCCHHEE
TNVKAPIRDAQGLINEALSAPEYQAEASSNAQTSVANKASQARSDLYRYLMNGVSHMIPF
CCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVTGGLLIALALAVGGQPSEAGMAIPEGSMWNQILNVGVVAFTLMIPILAGYIAYAIADR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALAPGLIGGWIANNGSFYGADAGTGFIGAIIAGLLVGYFVKWITSINYHKFIQPLVPIM
CCCCCCHHHCEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAPITGSLFIAGLFIFVIGAPIASLMDGLTALLTSMSTGNVVLLGIVLGGMAGFDMGGPF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCH
NKVAFLFSVGMIASGQTQFMGAMACAIPVAPLGMALATALGRKFDLFEESETEAGKAAGA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
MGLVGISEGAIPFAAQDPMSVIPANVLGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNH
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
PVLALICMAAGAVVTAVTCVTLKKVRKAKMMQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]