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The map label for this gene is arsR [H]

Identifier: 156976331

GI number: 156976331

Start: 341766

End: 342512

Strand: Reverse

Name: arsR [H]

Synonym: VIBHAR_05104

Alternate gene names: 156976331

Gene position: 342512-341766 (Counterclockwise)

Preceding gene: 156976334

Following gene: 156976330

Centisome position: 15.54

GC content: 43.64

Gene sequence:

>747_bases
ATGATGAAAAAACAAGTCCTGTTTCTTTGCACCGGTAACTCCGCTCGCTCACAACTTGCCGAAGCGATCTTCAACCATAT
GGCAGGTGAAATGTTCCATGCCGAAAGCGCAGGAGTCCACCCAAGTGACGTCGACACAAGAGTGTTTGATGTATTGAAAG
CGCATCAAATAAGTCATGAAGGACTTCGTTCGAAAGACTACGCAGAAGTGGGAAAGAATCACTATGACTTCGTCATTACA
TTGTGTGATAACGCCAAAGATGAATGCGTGATCTTCGACCAAGACATCGACCAATTACATTGGAACCTCGTCGACCCAAA
ACCGCTTGAAGGTGTCGAACCTTTCCACAATACGGCAAAAGAATTGATTGAGAGAATCAGTCTATTTCTACTCCTCAACA
GTGAAGAAAACCGCACACAAGTGGATCCGAGCAATTTCTTTAAGCTGATGAGCGATCCGCTGCGACTCAAGATATTGATG
CTGTTAGAAGATGAACAAGATCTAACCGTAACCGATTTGAAAAACGCTTTGAATGAAAGCCAGCCAAAAGTCTCTCGCCA
CCTAGCTTTACTAAGAGACACGACATTCTTGAAAGATACCCGACATGGTCTTTGGATTCATTATCGCTTATCCCCATCTT
TGCCTATGTGGATTAAACATTTACTCCAAACCGTTCGCATTGGGAATCCAGGTATAATCAACGCAGAGAAGTCACGTTTA
AAAGCCACGCAAAACAACGAGCAATAG

Upstream 100 bases:

>100_bases
ACCAAGGAAAGATACGTGCTTCTTGTTCAACTCTCAGAAGGTTATACTGTTGCGTATCAATGGTCATTTTGACGCAAGCC
TCTGAAATCCATAGTTTGAT

Downstream 100 bases:

>100_bases
TCGCTTAGCTCTCTTTTATTTACCTCTCACCCCCTCGAGGCACTGCATAAAATTTTTATTGGAAGCAGTGTCTCCTTGTC
ATGATCTCGTCAATTCTATG

Product: arsenate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MMKKQVLFLCTGNSARSQLAEAIFNHMAGEMFHAESAGVHPSDVDTRVFDVLKAHQISHEGLRSKDYAEVGKNHYDFVIT
LCDNAKDECVIFDQDIDQLHWNLVDPKPLEGVEPFHNTAKELIERISLFLLLNSEENRTQVDPSNFFKLMSDPLRLKILM
LLEDEQDLTVTDLKNALNESQPKVSRHLALLRDTTFLKDTRHGLWIHYRLSPSLPMWIKHLLQTVRIGNPGIINAEKSRL
KATQNNEQ

Sequences:

>Translated_248_residues
MMKKQVLFLCTGNSARSQLAEAIFNHMAGEMFHAESAGVHPSDVDTRVFDVLKAHQISHEGLRSKDYAEVGKNHYDFVIT
LCDNAKDECVIFDQDIDQLHWNLVDPKPLEGVEPFHNTAKELIERISLFLLLNSEENRTQVDPSNFFKLMSDPLRLKILM
LLEDEQDLTVTDLKNALNESQPKVSRHLALLRDTTFLKDTRHGLWIHYRLSPSLPMWIKHLLQTVRIGNPGIINAEKSRL
KATQNNEQ
>Mature_248_residues
MMKKQVLFLCTGNSARSQLAEAIFNHMAGEMFHAESAGVHPSDVDTRVFDVLKAHQISHEGLRSKDYAEVGKNHYDFVIT
LCDNAKDECVIFDQDIDQLHWNLVDPKPLEGVEPFHNTAKELIERISLFLLLNSEENRTQVDPSNFFKLMSDPLRLKILM
LLEDEQDLTVTDLKNALNESQPKVSRHLALLRDTTFLKDTRHGLWIHYRLSPSLPMWIKHLLQTVRIGNPGIINAEKSRL
KATQNNEQ

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=80, Percent_Identity=48.75, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 28464; Mature: 28464

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKQVLFLCTGNSARSQLAEAIFNHMAGEMFHAESAGVHPSDVDTRVFDVLKAHQISHE
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
GLRSKDYAEVGKNHYDFVITLCDNAKDECVIFDQDIDQLHWNLVDPKPLEGVEPFHNTAK
CCCCCCHHHHCCCCCEEEEEEECCCCCCEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHH
ELIERISLFLLLNSEENRTQVDPSNFFKLMSDPLRLKILMLLEDEQDLTVTDLKNALNES
HHHHHHHEEEEECCCCCCCCCCHHHHHHHHCCCHHEEEEEEEECCCCCHHHHHHHHHCCC
QPKVSRHLALLRDTTFLKDTRHGLWIHYRLSPSLPMWIKHLLQTVRIGNPGIINAEKSRL
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEECCHHHHH
KATQNNEQ
HCCCCCCC
>Mature Secondary Structure
MMKKQVLFLCTGNSARSQLAEAIFNHMAGEMFHAESAGVHPSDVDTRVFDVLKAHQISHE
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
GLRSKDYAEVGKNHYDFVITLCDNAKDECVIFDQDIDQLHWNLVDPKPLEGVEPFHNTAK
CCCCCCHHHHCCCCCEEEEEEECCCCCCEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHH
ELIERISLFLLLNSEENRTQVDPSNFFKLMSDPLRLKILMLLEDEQDLTVTDLKNALNES
HHHHHHHEEEEECCCCCCCCCCHHHHHHHHCCCHHEEEEEEEECCCCCHHHHHHHHHCCC
QPKVSRHLALLRDTTFLKDTRHGLWIHYRLSPSLPMWIKHLLQTVRIGNPGIINAEKSRL
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEECCHHHHH
KATQNNEQ
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]