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The map label for this gene is sstT [H]

Identifier: 156976068

GI number: 156976068

Start: 104504

End: 105727

Strand: Reverse

Name: sstT [H]

Synonym: VIBHAR_04838

Alternate gene names: 156976068

Gene position: 105727-104504 (Counterclockwise)

Preceding gene: 156976069

Following gene: 156976067

Centisome position: 4.8

GC content: 46.9

Gene sequence:

>1224_bases
ATGCAAATGCAACACAACAGTCTCGTTGCCCGATACGCTCGCGGTAACCTCGTTCTCCAAATCCTTGTCGGTATCGTCTT
TGGTATCTTGCTTGCAACGATCTCACCAAGCCACGCTGAAAGCGTTGGTATGCTGGGTAGTCTATTTGTAGGTGCGCTAA
AAGCGATTGCTCCAATATTGGTATTCATCTTGGTTGCTGCGTCTATCGCGAACCAAAAGAAAAACCAACACACTTACATG
CGTCCAATCGTAGTTCTTTACCTAGCGGGCACTTTCTTTGCAGCATTAACCGCAGTGTTACTAAGCTTCCTTTTCCCGAC
CAATCTAACGCTAGTAACGGGCGCTGAAGGTGCAACGCCACCACAAGGTATTGCAGAAGTTATCCAAACCTTGTTGTTCA
AACTGGTTGATAACCCAGTAAACGCGCTAGTAGAAGCAAACTACATCGGTATTCTTGCTTGGGGTGTGGGTCTGGGTCTT
GCACTTCACCACGCATCAGCAACGACAAAAGCGGTATTCGAAGATCTAAGCCACAGTGTTTCTCACATTGTTCGCTTTAT
CATTCGTCTTGCTCCTTTCGGTATCTTCGGTTTGGTTGCATCTACATTTGCAACAACTGGTTTTGGCGCGCTAGCGAGCT
ACGCTCATCTTCTAGCGGTACTATTGGGTTCAATGTTTATCATTGCACTAGTGGTTAACCCAGCGATCGTATACTTCAAA
ACGAAAGAAAACCCATACCCATTGGTGTTCCAATGTCTACGTGAAAGTGGCGTAACGGCATTCTTTACGCGTTCAAGTGC
TGCGAACATTCCAGTGAACATGAACCTGTGTAAGAAGCTAGACCTAGACGAAGATACGTACTCAGTGTCTATCCCACTAG
GTGCGACCATTAACATGGCGGGTGCAGCAATCACTATCACTACCCTAACGCTAGCAGCGGTACACACTATGGGTATCGAA
GTTGACCTAATGACGGCAGTACTACTAAGTGTTGTTGCAGCGGTATCAGCGTGTGGCGCATCAGGTGTTGCAGGTGGTTC
TCTACTACTTATCCCACTAGCATGTGGTCTGTTTGGTATCTCAAACGACGTAGCAATGCAGGTTGTAGCGGTTGGCTTCA
TCATCGGTGTGATTCAAGACTCGGCTGAAACAGCGCTAAACAGCTCAACAGACGTTATCTTCACTGCCGCTGTTTGCAAA
TCAGAACAGCAAAAAGCTCAGTAA

Upstream 100 bases:

>100_bases
CGCAATAACAAGATTCAGCCCCCTTAACGCAAGGGAATATTACGCCGTGTGATGACTGAATTTGCGCTGTTGCTGAGGCA
AAAAATTGCAGGAATGATGT

Downstream 100 bases:

>100_bases
GACTTAAACATCTTTAAGATCTCAATAATAGAAAGGGGAGCCAACGCGGCTCCCCTTTTTTGTGTAAACGTCAATTAATA
CCGCCACACCAAACGAATTC

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MQMQHNSLVARYARGNLVLQILVGIVFGILLATISPSHAESVGMLGSLFVGALKAIAPILVFILVAASIANQKKNQHTYM
RPIVVLYLAGTFFAALTAVLLSFLFPTNLTLVTGAEGATPPQGIAEVIQTLLFKLVDNPVNALVEANYIGILAWGVGLGL
ALHHASATTKAVFEDLSHSVSHIVRFIIRLAPFGIFGLVASTFATTGFGALASYAHLLAVLLGSMFIIALVVNPAIVYFK
TKENPYPLVFQCLRESGVTAFFTRSSAANIPVNMNLCKKLDLDEDTYSVSIPLGATINMAGAAITITTLTLAAVHTMGIE
VDLMTAVLLSVVAAVSACGASGVAGGSLLLIPLACGLFGISNDVAMQVVAVGFIIGVIQDSAETALNSSTDVIFTAAVCK
SEQQKAQ

Sequences:

>Translated_407_residues
MQMQHNSLVARYARGNLVLQILVGIVFGILLATISPSHAESVGMLGSLFVGALKAIAPILVFILVAASIANQKKNQHTYM
RPIVVLYLAGTFFAALTAVLLSFLFPTNLTLVTGAEGATPPQGIAEVIQTLLFKLVDNPVNALVEANYIGILAWGVGLGL
ALHHASATTKAVFEDLSHSVSHIVRFIIRLAPFGIFGLVASTFATTGFGALASYAHLLAVLLGSMFIIALVVNPAIVYFK
TKENPYPLVFQCLRESGVTAFFTRSSAANIPVNMNLCKKLDLDEDTYSVSIPLGATINMAGAAITITTLTLAAVHTMGIE
VDLMTAVLLSVVAAVSACGASGVAGGSLLLIPLACGLFGISNDVAMQVVAVGFIIGVIQDSAETALNSSTDVIFTAAVCK
SEQQKAQ
>Mature_407_residues
MQMQHNSLVARYARGNLVLQILVGIVFGILLATISPSHAESVGMLGSLFVGALKAIAPILVFILVAASIANQKKNQHTYM
RPIVVLYLAGTFFAALTAVLLSFLFPTNLTLVTGAEGATPPQGIAEVIQTLLFKLVDNPVNALVEANYIGILAWGVGLGL
ALHHASATTKAVFEDLSHSVSHIVRFIIRLAPFGIFGLVASTFATTGFGALASYAHLLAVLLGSMFIIALVVNPAIVYFK
TKENPYPLVFQCLRESGVTAFFTRSSAANIPVNMNLCKKLDLDEDTYSVSIPLGATINMAGAAITITTLTLAAVHTMGIE
VDLMTAVLLSVVAAVSACGASGVAGGSLLLIPLACGLFGISNDVAMQVVAVGFIIGVIQDSAETALNSSTDVIFTAAVCK
SEQQKAQ

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=271, Percent_Identity=26.1992619926199, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223468566, Length=268, Percent_Identity=26.4925373134328, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789473, Length=398, Percent_Identity=67.0854271356784, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1789947, Length=351, Percent_Identity=23.6467236467236, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790514, Length=416, Percent_Identity=24.0384615384615, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537407, Length=451, Percent_Identity=23.7250554323725, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983099, Length=244, Percent_Identity=26.6393442622951, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71983106, Length=244, Percent_Identity=26.6393442622951, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71996953, Length=270, Percent_Identity=24.8148148148148, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206505, Length=464, Percent_Identity=22.198275862069, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 42520; Mature: 42520

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00435 PEROXIDASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMQHNSLVARYARGNLVLQILVGIVFGILLATISPSHAESVGMLGSLFVGALKAIAPIL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VFILVAASIANQKKNQHTYMRPIVVLYLAGTFFAALTAVLLSFLFPTNLTLVTGAEGATP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
PQGIAEVIQTLLFKLVDNPVNALVEANYIGILAWGVGLGLALHHASATTKAVFEDLSHSV
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHIVRFIIRLAPFGIFGLVASTFATTGFGALASYAHLLAVLLGSMFIIALVVNPAIVYFK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TKENPYPLVFQCLRESGVTAFFTRSSAANIPVNMNLCKKLDLDEDTYSVSIPLGATINMA
ECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCEEECC
GAAITITTLTLAAVHTMGIEVDLMTAVLLSVVAAVSACGASGVAGGSLLLIPLACGLFGI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
SNDVAMQVVAVGFIIGVIQDSAETALNSSTDVIFTAAVCKSEQQKAQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCHHHHCC
>Mature Secondary Structure
MQMQHNSLVARYARGNLVLQILVGIVFGILLATISPSHAESVGMLGSLFVGALKAIAPIL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VFILVAASIANQKKNQHTYMRPIVVLYLAGTFFAALTAVLLSFLFPTNLTLVTGAEGATP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
PQGIAEVIQTLLFKLVDNPVNALVEANYIGILAWGVGLGLALHHASATTKAVFEDLSHSV
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHIVRFIIRLAPFGIFGLVASTFATTGFGALASYAHLLAVLLGSMFIIALVVNPAIVYFK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TKENPYPLVFQCLRESGVTAFFTRSSAANIPVNMNLCKKLDLDEDTYSVSIPLGATINMA
ECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCEEECC
GAAITITTLTLAAVHTMGIEVDLMTAVLLSVVAAVSACGASGVAGGSLLLIPLACGLFGI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
SNDVAMQVVAVGFIIGVIQDSAETALNSSTDVIFTAAVCKSEQQKAQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]