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The map label for this gene is ahpC [H]

Identifier: 156975992

GI number: 156975992

Start: 29686

End: 30243

Strand: Reverse

Name: ahpC [H]

Synonym: VIBHAR_04762

Alternate gene names: 156975992

Gene position: 30243-29686 (Counterclockwise)

Preceding gene: 156975993

Following gene: 156975991

Centisome position: 1.37

GC content: 45.88

Gene sequence:

>558_bases
ATGATTAATACTCAAATCAAACCATTTGCAGCTACAGCGTACAAAAACGGCGAATTCGTTGAAGTAACAGAACAAGACGT
TCTAGGTAAATGGGCAGTATTCTTCTTCTACCCAGCAGACTTTACGTTTGTATGTCCAACAGAACTGGGCGACCTAGCAG
ACCACTACGAAGAGCTACAAAAACGTGGCGTAGAAGTTTACTCAGTATCAACTGACACACACTTCACTCATAAAGCATGG
CACGACAGCTCAGACACAATCGGTAAGATTCAGTACTACATGCTTGGCGACCAAACAGGCAACATCACAAACAACTTCGG
TGTGATGCGTGAAGGTCAAGGTCTTGCAGACCGTGCAACGTTCCTAATCGACCCTGAAGGTACTATCCAAGCAATGGAAA
TCACTGCTGAAGGTATCGGTCGTGACGCAGAAGACCTACTACGCAAAGTGAAAGCAGCTCAATACGTAGCAGCGCACCCA
GGCGAAGTTTGCCCAGCGAAATGGAAAGAAGGTGAAGAGACACTAGCTCCATCACTAGACCTAGTTGGCAAAATCTAA

Upstream 100 bases:

>100_bases
AGGATAGTTACAAGCGATTTTCCTTAAACACACTCCGATGAGAATATACTTTCCGAAAGCAACAACAGCTCAGCTTAAAA
CATTCAAAGGAAAGTAAATT

Downstream 100 bases:

>100_bases
GCCACTGAAATTTAAGTTCTAATCAGTTCCCGATTTCCTTTTTCTGATTAGAACTGAATTAGAGAGCACTTCAGGTTAGA
TACCTTGACGACCTTCTGCC

Product: alkyl hydroperoxide reductase c22 protein

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINTQIKPFAATAYKNGEFVEVTEQDVLGKWAVFFFYPADFTFVCPTELGDLADHYEELQKRGVEVYSVSTDTHFTHKAW
HDSSDTIGKIQYYMLGDQTGNITNNFGVMREGQGLADRATFLIDPEGTIQAMEITAEGIGRDAEDLLRKVKAAQYVAAHP
GEVCPAKWKEGEETLAPSLDLVGKI

Sequences:

>Translated_185_residues
MINTQIKPFAATAYKNGEFVEVTEQDVLGKWAVFFFYPADFTFVCPTELGDLADHYEELQKRGVEVYSVSTDTHFTHKAW
HDSSDTIGKIQYYMLGDQTGNITNNFGVMREGQGLADRATFLIDPEGTIQAMEITAEGIGRDAEDLLRKVKAAQYVAAHP
GEVCPAKWKEGEETLAPSLDLVGKI
>Mature_185_residues
MINTQIKPFAATAYKNGEFVEVTEQDVLGKWAVFFFYPADFTFVCPTELGDLADHYEELQKRGVEVYSVSTDTHFTHKAW
HDSSDTIGKIQYYMLGDQTGNITNNFGVMREGQGLADRATFLIDPEGTIQAMEITAEGIGRDAEDLLRKVKAAQYVAAHP
GEVCPAKWKEGEETLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=179, Percent_Identity=44.6927374301676, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=43.5754189944134, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=41.1428571428571, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI5453549, Length=178, Percent_Identity=42.1348314606742, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=37.7142857142857, Blast_Score=137, Evalue=6e-33,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=37.7142857142857, Blast_Score=137, Evalue=6e-33,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=37.7142857142857, Blast_Score=137, Evalue=6e-33,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=51.3513513513513, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4758638, Length=165, Percent_Identity=26.0606060606061, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786822, Length=185, Percent_Identity=77.8378378378378, Blast_Score=318, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=40.1129943502825, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=39.6551724137931, Blast_Score=140, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=39.6551724137931, Blast_Score=139, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=28.6585365853659, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=31.4917127071823, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=32.4175824175824, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=164, Percent_Identity=28.6585365853659, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=38.6740331491713, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=38.6740331491713, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=37.2881355932203, Blast_Score=136, Evalue=7e-33,
Organism=Drosophila melanogaster, GI21357347, Length=180, Percent_Identity=37.7777777777778, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17157991, Length=171, Percent_Identity=38.5964912280702, Blast_Score=133, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24641739, Length=171, Percent_Identity=38.5964912280702, Blast_Score=133, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24581278, Length=155, Percent_Identity=30.9677419354839, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=29.1139240506329, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20558; Mature: 20558

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTQIKPFAATAYKNGEFVEVTEQDVLGKWAVFFFYPADFTFVCPTELGDLADHYEELQ
CCCCCCCCEEEEEECCCCEEEECCHHHCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHH
KRGVEVYSVSTDTHFTHKAWHDSSDTIGKIQYYMLGDQTGNITNNFGVMREGQGLADRAT
HCCCEEEEEECCCCEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEECCCCCCCCEE
FLIDPEGTIQAMEITAEGIGRDAEDLLRKVKAAQYVAAHPGEVCPAKWKEGEETLAPSLD
EEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCH
LVGKI
HHCCC
>Mature Secondary Structure
MINTQIKPFAATAYKNGEFVEVTEQDVLGKWAVFFFYPADFTFVCPTELGDLADHYEELQ
CCCCCCCCEEEEEECCCCEEEECCHHHCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHH
KRGVEVYSVSTDTHFTHKAWHDSSDTIGKIQYYMLGDQTGNITNNFGVMREGQGLADRAT
HCCCEEEEEECCCCEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEECCCCCCCCEE
FLIDPEGTIQAMEITAEGIGRDAEDLLRKVKAAQYVAAHPGEVCPAKWKEGEETLAPSLD
EEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCH
LVGKI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]