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The map label for this gene is mcpA [H]

Identifier: 156975977

GI number: 156975977

Start: 16229

End: 17314

Strand: Reverse

Name: mcpA [H]

Synonym: VIBHAR_04747

Alternate gene names: 156975977

Gene position: 17314-16229 (Counterclockwise)

Preceding gene: 156975978

Following gene: 156975973

Centisome position: 0.79

GC content: 47.05

Gene sequence:

>1086_bases
ATGTTTGGATTAAAACGAATCAAATCGGAAAATGAGGCGCTTAAGCAAGAACTCGCAGACCTCAAAAAGAAGTACCAAAC
TGACGTTACTGTTCTGGAAAAACAGCTCCAAGAAACACAACAGCTTGTTCGCACTGCACAGCAAGAGCACCACAATAGCG
ACGAGTTGATGTCGAGCAGTTTGAAAGGCGGAGACATGCTCCAAACCATTCGAACCGAGATGGTTGAAAGTGCACAGTCG
ATGGCCCATGAAAACCAAGAGCTGCAACAACTTGATGAGATGTTTAAACAAACGCATCAAGCTCTTGCCCGCCTTGATAA
CCGAGCGGTGAAGATCAGCACTCAAGCTTCCCAAAGTATTGAATCAGTTCAAATATTAGATAACACCGCCACTTCTATCT
CTCATCTTGTATCGACGATTCAAGAGATTTCTGATCAAACCAATTTGCTCGCCTTAAATGCAGCGATTGAAGCCGCACGT
GCTGGCGAGGCTGGGCGTGGTTTTGCGGTGGTGGCTGACGAGGTAAGAAATCTGGCAGGTAAAGCCAGTGAGGCTAGTGA
ACAAATTGATTCGTTGGTGAATCAAGTGCTCACTCAGGTCTACGCGATTAAAACCTCTATCGATGAAAACCAGACCTGTG
CAGAAGAAGTTTCAGCATCTTCCGCACAAATTGGTTCTATCGTGAACGAAGTCGTCGTGAAATCGAAACACATGCAGCAG
GTGATTCATATTGCGTCCACCCGTGCTTTCTTGGACACAGTGAAACTTGATCACGCCATCTGGAAGAACAACATCTATCG
CTTACTACAGAGCGGAGCATTTGGTGAAACGGTGAATAGCCACTCAGAGTGTCGCTTAGGCCAGTGGTACTACCGTGGCG
ATGGCAAGGCTTACAGCCACCTAAGAAGCTATGCGCTACTTGAAGAACCACATAAAGGCGTGCACGACAACGGACGTGAA
GCAATGAGCCAAGCTAAATCTGGCAACATGTCAGCGATGGTGACCGCGATTAACGCCATGGAAGATGCCAGCGAACAAGT
GGTAGTGCAAATCGATCGCTTGATGGATGAGATTATCGCGAGTTAA

Upstream 100 bases:

>100_bases
AGTGTGATTCAGCTTGGCAAATATATGAATGTCATCGTGTATTAAATACTCAACTCGATTAGCATGGATTTTTTAACATC
TCGTTACATTTATAAAATCT

Downstream 100 bases:

>100_bases
AAGCTGCTCAATAACCCAACTAAAGCTCAAAAAGGGATGGTGAATGCCATCCCTTTTTTATTCTTCAATATACCCAAGTC
ACCTCAGGGGGCTTGAATAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MFGLKRIKSENEALKQELADLKKKYQTDVTVLEKQLQETQQLVRTAQQEHHNSDELMSSSLKGGDMLQTIRTEMVESAQS
MAHENQELQQLDEMFKQTHQALARLDNRAVKISTQASQSIESVQILDNTATSISHLVSTIQEISDQTNLLALNAAIEAAR
AGEAGRGFAVVADEVRNLAGKASEASEQIDSLVNQVLTQVYAIKTSIDENQTCAEEVSASSAQIGSIVNEVVVKSKHMQQ
VIHIASTRAFLDTVKLDHAIWKNNIYRLLQSGAFGETVNSHSECRLGQWYYRGDGKAYSHLRSYALLEEPHKGVHDNGRE
AMSQAKSGNMSAMVTAINAMEDASEQVVVQIDRLMDEIIAS

Sequences:

>Translated_361_residues
MFGLKRIKSENEALKQELADLKKKYQTDVTVLEKQLQETQQLVRTAQQEHHNSDELMSSSLKGGDMLQTIRTEMVESAQS
MAHENQELQQLDEMFKQTHQALARLDNRAVKISTQASQSIESVQILDNTATSISHLVSTIQEISDQTNLLALNAAIEAAR
AGEAGRGFAVVADEVRNLAGKASEASEQIDSLVNQVLTQVYAIKTSIDENQTCAEEVSASSAQIGSIVNEVVVKSKHMQQ
VIHIASTRAFLDTVKLDHAIWKNNIYRLLQSGAFGETVNSHSECRLGQWYYRGDGKAYSHLRSYALLEEPHKGVHDNGRE
AMSQAKSGNMSAMVTAINAMEDASEQVVVQIDRLMDEIIAS
>Mature_361_residues
MFGLKRIKSENEALKQELADLKKKYQTDVTVLEKQLQETQQLVRTAQQEHHNSDELMSSSLKGGDMLQTIRTEMVESAQS
MAHENQELQQLDEMFKQTHQALARLDNRAVKISTQASQSIESVQILDNTATSISHLVSTIQEISDQTNLLALNAAIEAAR
AGEAGRGFAVVADEVRNLAGKASEASEQIDSLVNQVLTQVYAIKTSIDENQTCAEEVSASSAQIGSIVNEVVVKSKHMQQ
VIHIASTRAFLDTVKLDHAIWKNNIYRLLQSGAFGETVNSHSECRLGQWYYRGDGKAYSHLRSYALLEEPHKGVHDNGRE
AMSQAKSGNMSAMVTAINAMEDASEQVVVQIDRLMDEIIAS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=228, Percent_Identity=32.0175438596491, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788194, Length=128, Percent_Identity=36.71875, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788195, Length=81, Percent_Identity=46.9135802469136, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787690, Length=220, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789453, Length=162, Percent_Identity=34.5679012345679, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 39913; Mature: 39913

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLKRIKSENEALKQELADLKKKYQTDVTVLEKQLQETQQLVRTAQQEHHNSDELMSSS
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LKGGDMLQTIRTEMVESAQSMAHENQELQQLDEMFKQTHQALARLDNRAVKISTQASQSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
ESVQILDNTATSISHLVSTIQEISDQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
KASEASEQIDSLVNQVLTQVYAIKTSIDENQTCAEEVSASSAQIGSIVNEVVVKSKHMQQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIHIASTRAFLDTVKLDHAIWKNNIYRLLQSGAFGETVNSHSECRLGQWYYRGDGKAYSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHH
LRSYALLEEPHKGVHDNGREAMSQAKSGNMSAMVTAINAMEDASEQVVVQIDRLMDEIIA
HHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
S
C
>Mature Secondary Structure
MFGLKRIKSENEALKQELADLKKKYQTDVTVLEKQLQETQQLVRTAQQEHHNSDELMSSS
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LKGGDMLQTIRTEMVESAQSMAHENQELQQLDEMFKQTHQALARLDNRAVKISTQASQSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
ESVQILDNTATSISHLVSTIQEISDQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
KASEASEQIDSLVNQVLTQVYAIKTSIDENQTCAEEVSASSAQIGSIVNEVVVKSKHMQQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIHIASTRAFLDTVKLDHAIWKNNIYRLLQSGAFGETVNSHSECRLGQWYYRGDGKAYSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHH
LRSYALLEEPHKGVHDNGREAMSQAKSGNMSAMVTAINAMEDASEQVVVQIDRLMDEIIA
HHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]