Definition Ignicoccus hospitalis KIN4/I chromosome, complete genome.
Accession NC_009776
Length 1,297,538

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The map label for this gene is sav [H]

Identifier: 156938218

GI number: 156938218

Start: 1285613

End: 1287802

Strand: Direct

Name: sav [H]

Synonym: Igni_1431

Alternate gene names: 156938218

Gene position: 1285613-1287802 (Clockwise)

Preceding gene: 156938217

Following gene: 156938220

Centisome position: 99.08

GC content: 57.12

Gene sequence:

>2190_bases
TTGGCTCTGCTCCCGGTAAGAGTCTTGGCGAAGGAACTCCGACTGAGGGTCGCTGAGGCAAAACAGAGGGACGTCGGGAG
AAAGATCGCTAGGATCAGTAGGAAGAATATGAGGGAGTTGGACGTAGTCACTGGAGACTTCGTCGAAGTAGAGGGTCCTA
AGGGCAGCATAGTACTCCAAGTCTGGCCCGCCTACCCCCAAGACGAAGATAAGGACATAATCAGGATGGACGGCTACGCG
AGGAACCAGATAGGCGTCAGCGTGGGAGATTACGTGACCGTAAGGAAGACTAAGGTAGAAGAAGCTACCAGAGTGGTGTT
GGCCCCCACCGAGCCCTTGGAGTTCGGCCCCGACTTCGTCGACTACGTAAAGAGGATATTAATGGGCAAGCCCCTAATGA
GGGGAGAGAAGGTACAGATACCGTTCTTCGGGAGCACCATAGAACTGATAGTCACCGCCACCCAGCCCAGCCCGAGAGTT
TACGTAACTGACAAAACCGAGATCGAGATAAGCAAGAAGCCGGTCAAGGAGGAAGCCGTCAGGGGCGTGCCTAAGGTAAC
TTGGGAGGACATAGGCGACCTCGAGGAGGCTAAGGAAAGGCTGAGGGAGATAGTCGAGCTGCCCATGAAACACCCGGAGA
TCTTCAGGCATTTGGGCATCGAGCCCCCGAAGGGAGTGCTCCTCTACGGTCCCCCCGGCACCGGTAAGACCATGTTGGCC
AAGGCCCTAGCCAACGAGATAGGCGCATACTTCATAGCGATAAATGGACCAGAAATAATGAGCAAGTACTACGGCGAGAG
CGAGCAGAGGCTTAGGGAGATCTTCGAGGAGGCGCGCAAGAACGCTCCGAGCATAATATTCATAGACGAGATAGACGCAA
TTGCCCCCAAGAGGGAGGAGGTAACCGGAGAGGTCGAGAAGAGGGTCGTCGCTCAGTTGTTGACCTTGATGGACGGCCTC
CAAGAGAGGGGCAGGGTTGTGGTAATAGGTGCGACCAACAGGCCGGACGCCATAGACCCCGCCCTCAGGAGGCCCGGGAG
GTTTGATAGAGAAATAGAGATCCCGCCGCCGGACAAGAGGGCTAGGAAGGCCATCTTAGAAGTTCACACGAGGAACGTCC
CCCTGGCCGAGGACGTAGATCTAGACCGGATAGCGGAGATGACCCACGGTTACACCGGAGCGGACTTGGCGGCGTTAGTA
AAAGAGGCCGCAATGAACGCGCTGAGGAGGTTCTTCAAAGAGAAAGGAATAGACTTGACCAAGGTTGAGAAGGTGCCGGC
GAGCGAACTGGAGAAGCTGAAGGTGACCTTCCGCGACTTCCTCGCCGCCATGAAGGTTGTGCAACCGACGCTCATGAGAG
AGGTTTACATAGAGGTGCCAGAGGTACACTGGGAAGACATAGGCGGCCTCGAGGACGTGAAGCAACAGCTGAAGGAGGCC
GTCGTCTGGCCGCTGAAGCACCCCGAGTTCTTCACCGAGATGGGCATAGAGCCGCCGAAGGGGATACTCCTCTTCGGTCC
TCCCGGCACCGGTAAGACCTTGCTCGCCAAGGCGGCTGCCACGGAGAGCCAAGCGAACTTCATAGCGGTCAGGGGACCGG
AGATCTTGAGCAAGTGGGTAGGCGAGAGCGAGAAGGCGATAAGGGAGATCTTCCGCAAGGCCAGGCAAGCGGCCCCGACC
ATAGTGTTCTTCGACGAGATAGACAGCATCGCGGCCAGGAGGGGCAAAGACGTAAGCGGCGTGATAGACAGAATAGTCAA
CCAGCTGCTAACCGAGATGGACGGCATAGAGCCGCTCCAGAGGGTTACGGTAATAGCCGCGACCAACAGGCCAGACCTCT
TGGACCCTGCGCTGCTGAGGCCCGGGAGGTTCGACAGGCTGATCTACGTCCCGCCGCCAGATAAGAAGGCGAGGTTGGAG
ATATTCAAGGTCCACACCAGAAGGATGCCGCTGGCGGACGACGTGGACTTGGAGAAGTTGGCGGACATGACCCAAGGCTA
CACTGGCGCCGACATAGCGGCGCTCTGCAGGGAAGCGGCGTTGATCGCCTTAAGGGAGAACATGAAGCCGGTCCCAGTAA
CCATGAAGCACTTCGAGAGGGCGATGAAGGCGGTAAGGCCAAGCTTGAAGAGAGAAGACATACTGAGGTACGAGAGGTTG
GCAGAAGAGGTGAAGAGGAGCGCTATCTAA

Upstream 100 bases:

>100_bases
TCCCGTGTTCGTCAAGATAGAACGTGCTATGTCGAGGATAGCGCGCCTCGTCGTGGTCAGAGAGGAGCTACGGCAGTGTC
CTAACTCTTAACTTCGCCTT

Downstream 100 bases:

>100_bases
GCTCCTCTTTTACAAGGCGGATTGTTGGGATCATCTACCTTTATTTTCAGCTTCAAGCACATTTTGGTCAACTCCGAGTA
GAATATGCACTCGTGGCACG

Product: ATPase AAA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MALLPVRVLAKELRLRVAEAKQRDVGRKIARISRKNMRELDVVTGDFVEVEGPKGSIVLQVWPAYPQDEDKDIIRMDGYA
RNQIGVSVGDYVTVRKTKVEEATRVVLAPTEPLEFGPDFVDYVKRILMGKPLMRGEKVQIPFFGSTIELIVTATQPSPRV
YVTDKTEIEISKKPVKEEAVRGVPKVTWEDIGDLEEAKERLREIVELPMKHPEIFRHLGIEPPKGVLLYGPPGTGKTMLA
KALANEIGAYFIAINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGL
QERGRVVVIGATNRPDAIDPALRRPGRFDREIEIPPPDKRARKAILEVHTRNVPLAEDVDLDRIAEMTHGYTGADLAALV
KEAAMNALRRFFKEKGIDLTKVEKVPASELEKLKVTFRDFLAAMKVVQPTLMREVYIEVPEVHWEDIGGLEDVKQQLKEA
VVWPLKHPEFFTEMGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPT
IVFFDEIDSIAARRGKDVSGVIDRIVNQLLTEMDGIEPLQRVTVIAATNRPDLLDPALLRPGRFDRLIYVPPPDKKARLE
IFKVHTRRMPLADDVDLEKLADMTQGYTGADIAALCREAALIALRENMKPVPVTMKHFERAMKAVRPSLKREDILRYERL
AEEVKRSAI

Sequences:

>Translated_729_residues
MALLPVRVLAKELRLRVAEAKQRDVGRKIARISRKNMRELDVVTGDFVEVEGPKGSIVLQVWPAYPQDEDKDIIRMDGYA
RNQIGVSVGDYVTVRKTKVEEATRVVLAPTEPLEFGPDFVDYVKRILMGKPLMRGEKVQIPFFGSTIELIVTATQPSPRV
YVTDKTEIEISKKPVKEEAVRGVPKVTWEDIGDLEEAKERLREIVELPMKHPEIFRHLGIEPPKGVLLYGPPGTGKTMLA
KALANEIGAYFIAINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGL
QERGRVVVIGATNRPDAIDPALRRPGRFDREIEIPPPDKRARKAILEVHTRNVPLAEDVDLDRIAEMTHGYTGADLAALV
KEAAMNALRRFFKEKGIDLTKVEKVPASELEKLKVTFRDFLAAMKVVQPTLMREVYIEVPEVHWEDIGGLEDVKQQLKEA
VVWPLKHPEFFTEMGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPT
IVFFDEIDSIAARRGKDVSGVIDRIVNQLLTEMDGIEPLQRVTVIAATNRPDLLDPALLRPGRFDRLIYVPPPDKKARLE
IFKVHTRRMPLADDVDLEKLADMTQGYTGADIAALCREAALIALRENMKPVPVTMKHFERAMKAVRPSLKREDILRYERL
AEEVKRSAI
>Mature_728_residues
ALLPVRVLAKELRLRVAEAKQRDVGRKIARISRKNMRELDVVTGDFVEVEGPKGSIVLQVWPAYPQDEDKDIIRMDGYAR
NQIGVSVGDYVTVRKTKVEEATRVVLAPTEPLEFGPDFVDYVKRILMGKPLMRGEKVQIPFFGSTIELIVTATQPSPRVY
VTDKTEIEISKKPVKEEAVRGVPKVTWEDIGDLEEAKERLREIVELPMKHPEIFRHLGIEPPKGVLLYGPPGTGKTMLAK
ALANEIGAYFIAINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQ
ERGRVVVIGATNRPDAIDPALRRPGRFDREIEIPPPDKRARKAILEVHTRNVPLAEDVDLDRIAEMTHGYTGADLAALVK
EAAMNALRRFFKEKGIDLTKVEKVPASELEKLKVTFRDFLAAMKVVQPTLMREVYIEVPEVHWEDIGGLEDVKQQLKEAV
VWPLKHPEFFTEMGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPTI
VFFDEIDSIAARRGKDVSGVIDRIVNQLLTEMDGIEPLQRVTVIAATNRPDLLDPALLRPGRFDRLIYVPPPDKKARLEI
FKVHTRRMPLADDVDLEKLADMTQGYTGADIAALCREAALIALRENMKPVPVTMKHFERAMKAVRPSLKREDILRYERLA
EEVKRSAI

Specific function: Not yet known, shows ATPase activity [H]

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005942, Length=749, Percent_Identity=46.8624833110814, Blast_Score=652, Evalue=0.0,
Organism=Homo sapiens, GI157671927, Length=538, Percent_Identity=55.3903345724907, Blast_Score=602, Evalue=1e-172,
Organism=Homo sapiens, GI45643125, Length=601, Percent_Identity=45.2579034941764, Blast_Score=523, Evalue=1e-148,
Organism=Homo sapiens, GI45643123, Length=601, Percent_Identity=45.2579034941764, Blast_Score=523, Evalue=1e-148,
Organism=Homo sapiens, GI229577436, Length=753, Percent_Identity=39.5750332005312, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI4505725, Length=481, Percent_Identity=40.1247401247401, Blast_Score=328, Evalue=8e-90,
Organism=Homo sapiens, GI194018488, Length=518, Percent_Identity=36.8725868725869, Blast_Score=306, Evalue=4e-83,
Organism=Homo sapiens, GI24430151, Length=249, Percent_Identity=49.3975903614458, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI24497435, Length=251, Percent_Identity=47.0119521912351, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI24497618, Length=277, Percent_Identity=45.8483754512635, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI153792536, Length=277, Percent_Identity=45.8483754512635, Blast_Score=237, Evalue=3e-62,
Organism=Homo sapiens, GI5729991, Length=249, Percent_Identity=46.1847389558233, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI195539395, Length=275, Percent_Identity=42.5454545454545, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI24430155, Length=249, Percent_Identity=46.1847389558233, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI89064750, Length=249, Percent_Identity=46.1847389558233, Blast_Score=229, Evalue=7e-60,
Organism=Homo sapiens, GI21361144, Length=271, Percent_Identity=42.8044280442804, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI4506209, Length=262, Percent_Identity=44.2748091603053, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI5901990, Length=293, Percent_Identity=44.3686006825939, Blast_Score=222, Evalue=1e-57,
Organism=Homo sapiens, GI300192933, Length=261, Percent_Identity=46.7432950191571, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI14149767, Length=294, Percent_Identity=41.8367346938776, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI62177112, Length=294, Percent_Identity=41.8367346938776, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI7019569, Length=276, Percent_Identity=40.2173913043478, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4507173, Length=264, Percent_Identity=42.0454545454545, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI156564401, Length=389, Percent_Identity=37.2750642673522, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI31742536, Length=282, Percent_Identity=38.2978723404255, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI112789543, Length=282, Percent_Identity=38.2978723404255, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI17865802, Length=246, Percent_Identity=42.2764227642276, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI7657689, Length=268, Percent_Identity=42.1641791044776, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI226371754, Length=271, Percent_Identity=38.7453874538745, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI21327685, Length=268, Percent_Identity=42.1641791044776, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI310125280, Length=242, Percent_Identity=42.9752066115703, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI310125282, Length=251, Percent_Identity=42.2310756972112, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI31377644, Length=315, Percent_Identity=35.8730158730159, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI11875211, Length=307, Percent_Identity=36.8078175895765, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI40806170, Length=307, Percent_Identity=36.8078175895765, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI64084766, Length=280, Percent_Identity=31.0714285714286, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=44.9275362318841, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI116292174, Length=258, Percent_Identity=29.8449612403101, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI40255052, Length=291, Percent_Identity=24.3986254295533, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI11321607, Length=206, Percent_Identity=29.126213592233, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI75677353, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789568, Length=258, Percent_Identity=44.5736434108527, Blast_Score=219, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17532375, Length=760, Percent_Identity=44.6052631578947, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17531535, Length=754, Percent_Identity=44.0318302387268, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI17537217, Length=601, Percent_Identity=41.5973377703827, Blast_Score=440, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17508053, Length=521, Percent_Identity=39.9232245681382, Blast_Score=346, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17554786, Length=251, Percent_Identity=46.6135458167331, Blast_Score=241, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI25153574, Length=516, Percent_Identity=32.3643410852713, Blast_Score=241, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17562804, Length=474, Percent_Identity=32.2784810126582, Blast_Score=238, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17563250, Length=251, Percent_Identity=46.6135458167331, Blast_Score=237, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI25144278, Length=251, Percent_Identity=45.4183266932271, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI25144281, Length=251, Percent_Identity=45.4183266932271, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71987364, Length=242, Percent_Identity=44.6280991735537, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI193206116, Length=282, Percent_Identity=45.0354609929078, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71987372, Length=242, Percent_Identity=44.6280991735537, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI193206114, Length=282, Percent_Identity=45.0354609929078, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI133931034, Length=282, Percent_Identity=45.0354609929078, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI193209502, Length=259, Percent_Identity=44.4015444015444, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17505546, Length=256, Percent_Identity=44.921875, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=46.2151394422311, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17508701, Length=273, Percent_Identity=41.025641025641, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17563248, Length=262, Percent_Identity=41.9847328244275, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71994521, Length=266, Percent_Identity=45.4887218045113, Blast_Score=200, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI25146157, Length=283, Percent_Identity=38.5159010600707, Blast_Score=185, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI86561515, Length=241, Percent_Identity=41.0788381742739, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17554264, Length=224, Percent_Identity=44.1964285714286, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI133901662, Length=446, Percent_Identity=32.5112107623318, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32563584, Length=304, Percent_Identity=38.8157894736842, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI133901658, Length=446, Percent_Identity=32.5112107623318, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17560432, Length=272, Percent_Identity=38.2352941176471, Blast_Score=175, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17508421, Length=282, Percent_Identity=40.0709219858156, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI115534323, Length=256, Percent_Identity=41.015625, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17541224, Length=241, Percent_Identity=37.7593360995851, Blast_Score=158, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17541226, Length=241, Percent_Identity=37.7593360995851, Blast_Score=158, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17570397, Length=125, Percent_Identity=41.6, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566590, Length=125, Percent_Identity=41.6, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71990294, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320077, Length=741, Percent_Identity=45.0742240215924, Blast_Score=621, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6323429, Length=572, Percent_Identity=48.951048951049, Blast_Score=546, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6322994, Length=640, Percent_Identity=39.375, Blast_Score=479, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6324000, Length=566, Percent_Identity=33.5689045936396, Blast_Score=273, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6321709, Length=278, Percent_Identity=45.6834532374101, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6322651, Length=487, Percent_Identity=32.8542094455852, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321390, Length=251, Percent_Identity=45.0199203187251, Blast_Score=237, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6324833, Length=278, Percent_Identity=43.1654676258993, Blast_Score=227, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6320197, Length=249, Percent_Identity=46.1847389558233, Blast_Score=227, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6320602, Length=232, Percent_Identity=49.1379310344828, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320854, Length=278, Percent_Identity=44.2446043165468, Blast_Score=217, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6322704, Length=268, Percent_Identity=40.6716417910448, Blast_Score=214, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6323736, Length=261, Percent_Identity=44.8275862068966, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=237, Percent_Identity=43.0379746835443, Blast_Score=210, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6325431, Length=319, Percent_Identity=35.7366771159875, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6325281, Length=250, Percent_Identity=42, Blast_Score=197, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6325183, Length=290, Percent_Identity=35.8620689655172, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6320887, Length=309, Percent_Identity=34.9514563106796, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6321465, Length=268, Percent_Identity=42.5373134328358, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319554, Length=429, Percent_Identity=34.032634032634, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI9755327, Length=230, Percent_Identity=27.8260869565217, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320583, Length=160, Percent_Identity=32.5, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17137560, Length=751, Percent_Identity=45.8055925432756, Blast_Score=642, Evalue=0.0,
Organism=Drosophila melanogaster, GI161076486, Length=751, Percent_Identity=45.8055925432756, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI161076488, Length=728, Percent_Identity=46.2912087912088, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921202, Length=639, Percent_Identity=38.3411580594679, Blast_Score=431, Evalue=1e-120,
Organism=Drosophila melanogaster, GI21355121, Length=517, Percent_Identity=34.6228239845261, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24660075, Length=298, Percent_Identity=48.3221476510067, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI281365776, Length=298, Percent_Identity=48.3221476510067, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI45552965, Length=298, Percent_Identity=48.3221476510067, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24656825, Length=522, Percent_Identity=33.9080459770115, Blast_Score=286, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24656820, Length=541, Percent_Identity=32.5323475046211, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24652279, Length=259, Percent_Identity=48.6486486486487, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI281363136, Length=555, Percent_Identity=32.2522522522522, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI78707192, Length=555, Percent_Identity=32.2522522522522, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI19920408, Length=251, Percent_Identity=47.0119521912351, Blast_Score=245, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24649446, Length=249, Percent_Identity=48.5943775100402, Blast_Score=242, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24651451, Length=250, Percent_Identity=46.8, Blast_Score=240, Evalue=3e-63,
Organism=Drosophila melanogaster, GI281361487, Length=250, Percent_Identity=45.6, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI18860063, Length=249, Percent_Identity=46.5863453815261, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24640100, Length=275, Percent_Identity=43.2727272727273, Blast_Score=231, Evalue=2e-60,
Organism=Drosophila melanogaster, GI17137738, Length=262, Percent_Identity=43.5114503816794, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI17738151, Length=256, Percent_Identity=42.96875, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24665814, Length=271, Percent_Identity=45.3874538745387, Blast_Score=220, Evalue=3e-57,
Organism=Drosophila melanogaster, GI28574878, Length=271, Percent_Identity=45.3874538745387, Blast_Score=220, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24663015, Length=275, Percent_Identity=41.4545454545455, Blast_Score=219, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24644145, Length=298, Percent_Identity=39.9328859060403, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI18859657, Length=259, Percent_Identity=42.8571428571429, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24658770, Length=249, Percent_Identity=44.9799196787149, Blast_Score=200, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24581396, Length=275, Percent_Identity=39.6363636363636, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24639391, Length=250, Percent_Identity=42.4, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281360146, Length=295, Percent_Identity=36.9491525423729, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281360138, Length=295, Percent_Identity=36.9491525423729, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281360142, Length=295, Percent_Identity=36.9491525423729, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21357333, Length=295, Percent_Identity=36.9491525423729, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281360136, Length=295, Percent_Identity=36.9491525423729, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24644411, Length=295, Percent_Identity=36.9491525423729, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281360144, Length=295, Percent_Identity=36.9491525423729, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281360140, Length=295, Percent_Identity=36.9491525423729, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28573010, Length=384, Percent_Identity=35.15625, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17864540, Length=396, Percent_Identity=35.1010101010101, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28571849, Length=299, Percent_Identity=37.4581939799331, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI28571847, Length=299, Percent_Identity=37.4581939799331, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI20129423, Length=263, Percent_Identity=35.361216730038, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI20129529, Length=279, Percent_Identity=34.7670250896057, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24639486, Length=283, Percent_Identity=32.5088339222615, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=41.566265060241, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573181, Length=198, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129417, Length=147, Percent_Identity=31.9727891156463, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583262, Length=147, Percent_Identity=31.9727891156463, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 82044; Mature: 81912

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MALLPVRVLAKELRLRVAEAKQRDVGRKIARISRKNMRELDVVTGDFVEVEGPKGSIVLQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCEEEE
VWPAYPQDEDKDIIRMDGYARNQIGVSVGDYVTVRKTKVEEATRVVLAPTEPLEFGPDFV
ECCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHCEEEECCCCCCCCCCCHH
DYVKRILMGKPLMRGEKVQIPFFGSTIELIVTATQPSPRVYVTDKTEIEISKKPVKEEAV
HHHHHHHCCCCCCCCCEEEEEEECCEEEEEEEECCCCCEEEEECCCEEEECCCCCHHHHH
RGVPKVTWEDIGDLEEAKERLREIVELPMKHPEIFRHLGIEPPKGVLLYGPPGTGKTMLA
CCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHH
KALANEIGAYFIAINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREE
HHHHHHCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
VTGEVEKRVVAQLLTLMDGLQERGRVVVIGATNRPDAIDPALRRPGRFDREIEIPPPDKR
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCCCCEECCCCCCHH
ARKAILEVHTRNVPLAEDVDLDRIAEMTHGYTGADLAALVKEAAMNALRRFFKEKGIDLT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
KVEKVPASELEKLKVTFRDFLAAMKVVQPTLMREVYIEVPEVHWEDIGGLEDVKQQLKEA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHH
VVWPLKHPEFFTEMGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWV
HCCCCCCCHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHC
GESEKAIREIFRKARQAAPTIVFFDEIDSIAARRGKDVSGVIDRIVNQLLTEMDGIEPLQ
CCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHH
RVTVIAATNRPDLLDPALLRPGRFDRLIYVPPPDKKARLEIFKVHTRRMPLADDVDLEKL
HEEEEEECCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHEEEHHCCCCCCCCCCHHHH
ADMTQGYTGADIAALCREAALIALRENMKPVPVTMKHFERAMKAVRPSLKREDILRYERL
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AEEVKRSAI
HHHHHHHCC
>Mature Secondary Structure 
ALLPVRVLAKELRLRVAEAKQRDVGRKIARISRKNMRELDVVTGDFVEVEGPKGSIVLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCEEEE
VWPAYPQDEDKDIIRMDGYARNQIGVSVGDYVTVRKTKVEEATRVVLAPTEPLEFGPDFV
ECCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHCEEEECCCCCCCCCCCHH
DYVKRILMGKPLMRGEKVQIPFFGSTIELIVTATQPSPRVYVTDKTEIEISKKPVKEEAV
HHHHHHHCCCCCCCCCEEEEEEECCEEEEEEEECCCCCEEEEECCCEEEECCCCCHHHHH
RGVPKVTWEDIGDLEEAKERLREIVELPMKHPEIFRHLGIEPPKGVLLYGPPGTGKTMLA
CCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHH
KALANEIGAYFIAINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREE
HHHHHHCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
VTGEVEKRVVAQLLTLMDGLQERGRVVVIGATNRPDAIDPALRRPGRFDREIEIPPPDKR
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCCCCEECCCCCCHH
ARKAILEVHTRNVPLAEDVDLDRIAEMTHGYTGADLAALVKEAAMNALRRFFKEKGIDLT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
KVEKVPASELEKLKVTFRDFLAAMKVVQPTLMREVYIEVPEVHWEDIGGLEDVKQQLKEA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHH
VVWPLKHPEFFTEMGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWV
HCCCCCCCHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHC
GESEKAIREIFRKARQAAPTIVFFDEIDSIAARRGKDVSGVIDRIVNQLLTEMDGIEPLQ
CCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHH
RVTVIAATNRPDLLDPALLRPGRFDRLIYVPPPDKKARLEIFKVHTRRMPLADDVDLEKL
HEEEEEECCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHEEEHHCCCCCCCCCCHHHH
ADMTQGYTGADIAALCREAALIALRENMKPVPVTMKHFERAMKAVRPSLKREDILRYERL
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AEEVKRSAI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289263 [H]