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The map label for this gene is speB [H]

Identifier: 156938158

GI number: 156938158

Start: 1227119

End: 1227964

Strand: Direct

Name: speB [H]

Synonym: Igni_1371

Alternate gene names: 156938158

Gene position: 1227119-1227964 (Clockwise)

Preceding gene: 156938156

Following gene: 156938162

Centisome position: 94.57

GC content: 60.4

Gene sequence:

>846_bases
ATGGCTCAACCCCCCTTGGTCTTCGGCGGGCGGCTAGAGGAGGGCTCGCCCTACGCGGTGTTAGGGGTACCTCTGGAGCA
CGGGCCCACGTTTAGGGAAGGCACCCGGTGGGCCCCGTTAGAAGTTCGCAAGGCCTCCAACTACATCGAGTTTAGGTGTG
AGCTCAGCGGCTCGGACGCGGACCTCCTCGGGTTTTACGACTTGGGCGACGTCCCCGTGGTCAACGACGTGAAGGAGTCC
TTAAAGCTCGTCGAGGCTGAAGTAAGCTCGACTAAGAAAGTTCCTTTGATAATAGGGGGCGAACATACCCTCACTTACGC
CGCGCTAAAGGCCTTGAGGCCCGACTGCCTAGTGGTCTTCGACGCCCACTTGGACGCGAGGGACGAGTACGCGGGAGACC
CTTGGAGCCACGCGAGCTGGCTCAGGAGGGCGCTGGAGGAGCTCGAGCTCTCGAGGGTGGCGGTAGCCGGGGCCAGGGCG
TACGTCGAGGAGGAGGCCCGGTTCCTAGGGAAGAGAGGAGTGTTGTTCGGGAAAGACTTGAGAGGATTTTTAAAAAGGTA
CTTGAGGGGGTGCAAGTCGATATACGTAAGCTTGGACATGGACTACTTCGACCCCTCGGTGGTCCCCGGAGTCTCCAACC
CGGAGCCGGGGGGAGCGACGTTCTCGGACTTCTTAGAGCACGTAAAAGAGTTGCAACACTTGCCCTTAGCCGGCGCGGAC
GTGGTGGAGCTCTCCCCGCCCTACGACCCCTCCGGGGTCAGCGCGGTCTACGCCGCGAGGGCCCTCATAGAGTTAGCTAC
TTCTTTGAGACCTCTTTCTCGATCTCCTCTAAGTCCATCTCGTTGA

Upstream 100 bases:

>100_bases
TTTCGCCCTCACGAGCGCTTCCGTGGAGACGTCGCCCACCCTCCGGAGCAGTACCTTCAAAGTTCCCGTCCCTTCGTCCC
CTTCGTCGTGGGAGAGTATA

Downstream 100 bases:

>100_bases
GGACCTTCATTATCTCCTTGTACCTGTTTCTCACAGTGACCTCGGTTACTCCGGCAACGTTCGCTATCTCCTTCTGCGTC
CTCCTTTCGCCCTTCTGCAT

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MAQPPLVFGGRLEEGSPYAVLGVPLEHGPTFREGTRWAPLEVRKASNYIEFRCELSGSDADLLGFYDLGDVPVVNDVKES
LKLVEAEVSSTKKVPLIIGGEHTLTYAALKALRPDCLVVFDAHLDARDEYAGDPWSHASWLRRALEELELSRVAVAGARA
YVEEEARFLGKRGVLFGKDLRGFLKRYLRGCKSIYVSLDMDYFDPSVVPGVSNPEPGGATFSDFLEHVKELQHLPLAGAD
VVELSPPYDPSGVSAVYAARALIELATSLRPLSRSPLSPSR

Sequences:

>Translated_281_residues
MAQPPLVFGGRLEEGSPYAVLGVPLEHGPTFREGTRWAPLEVRKASNYIEFRCELSGSDADLLGFYDLGDVPVVNDVKES
LKLVEAEVSSTKKVPLIIGGEHTLTYAALKALRPDCLVVFDAHLDARDEYAGDPWSHASWLRRALEELELSRVAVAGARA
YVEEEARFLGKRGVLFGKDLRGFLKRYLRGCKSIYVSLDMDYFDPSVVPGVSNPEPGGATFSDFLEHVKELQHLPLAGAD
VVELSPPYDPSGVSAVYAARALIELATSLRPLSRSPLSPSR
>Mature_280_residues
AQPPLVFGGRLEEGSPYAVLGVPLEHGPTFREGTRWAPLEVRKASNYIEFRCELSGSDADLLGFYDLGDVPVVNDVKESL
KLVEAEVSSTKKVPLIIGGEHTLTYAALKALRPDCLVVFDAHLDARDEYAGDPWSHASWLRRALEELELSRVAVAGARAY
VEEEARFLGKRGVLFGKDLRGFLKRYLRGCKSIYVSLDMDYFDPSVVPGVSNPEPGGATFSDFLEHVKELQHLPLAGADV
VELSPPYDPSGVSAVYAARALIELATSLRPLSRSPLSPSR

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=279, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=6e-30,
Organism=Escherichia coli, GI1789306, Length=262, Percent_Identity=26.7175572519084, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 30755; Mature: 30624

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPPLVFGGRLEEGSPYAVLGVPLEHGPTFREGTRWAPLEVRKASNYIEFRCELSGSDA
CCCCCCEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCC
DLLGFYDLGDVPVVNDVKESLKLVEAEVSSTKKVPLIIGGEHTLTYAALKALRPDCLVVF
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCEEEEE
DAHLDARDEYAGDPWSHASWLRRALEELELSRVAVAGARAYVEEEARFLGKRGVLFGKDL
ECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHH
RGFLKRYLRGCKSIYVSLDMDYFDPSVVPGVSNPEPGGATFSDFLEHVKELQHLPLAGAD
HHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
VVELSPPYDPSGVSAVYAARALIELATSLRPLSRSPLSPSR
EEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AQPPLVFGGRLEEGSPYAVLGVPLEHGPTFREGTRWAPLEVRKASNYIEFRCELSGSDA
CCCCCEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCC
DLLGFYDLGDVPVVNDVKESLKLVEAEVSSTKKVPLIIGGEHTLTYAALKALRPDCLVVF
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCEEEEE
DAHLDARDEYAGDPWSHASWLRRALEELELSRVAVAGARAYVEEEARFLGKRGVLFGKDL
ECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHH
RGFLKRYLRGCKSIYVSLDMDYFDPSVVPGVSNPEPGGATFSDFLEHVKELQHLPLAGAD
HHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
VVELSPPYDPSGVSAVYAARALIELATSLRPLSRSPLSPSR
EEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]