Click here to switch to the map view.

The map label for this gene is hdrD [H]

Identifier: 156938156

GI number: 156938156

Start: 1225135

End: 1226574

Strand: Direct

Name: hdrD [H]

Synonym: Igni_1369

Alternate gene names: 156938156

Gene position: 1225135-1226574 (Clockwise)

Preceding gene: 156938155

Following gene: 156938158

Centisome position: 94.42

GC content: 53.96

Gene sequence:

>1440_bases
ATGAGCGAGAGTATGGACTTCTCCCGCATGATGCAAATGTTAATGTCTCAAAAGACGAGCATAGACGAAGCGATAAAGAA
GGCCATGAAAAAGGTAGACGCAGTGATGATACATTACATCGAGGACTGCTTGAACTGCGGCACGTGTTCGCCCGCTTGTC
CCTACTTCGTGGCGGGGCCGCAGTACAGCCCGGTCAACAAGGCAGAGGAGCTGAGGAAGATCTACCGCAGAGAGATGACC
ATACTGGGGAGACTGTTAGGCCCGCTGGTGGGCGCGGACAAGCCTAAGACTGAGGAAGACATGAAGAGGCTAATGGACCT
CGTATACGCTTGTACCAACTGCGGCCACTGCTACTACACTTGCACCGTAGGCATACACAGCGGAACTATGATAGGACTGC
TGAAGAGCATACTCACAGAAGCCGGCTACGTCCCCACCCTGCTGAACTTGTTCGAAGCCATAGAAGTTCAGAACATGCAC
ATGAAGATACCGGGCCTAAAGAAGGTCTGGGAAGACGCCCTCAAGGAGGCGCAAGAGAAGTACGGGGAAATAGAGTTCGA
CAAGCCTAACGTCGACGTATTCTTCTTGAGTTGGTTGACGGACGCTATGATGATGAGGGAAGGCTTCATAGCCACCATCG
GAATATTGAACAAGCTAAAGGAAGCCGGGCTCATCACTTGGACCACGTGGAGGGAGCCGCTGGGCATAAGGTCCCCGATC
TCGGTGGTCATCGGTAGGAGCGAGAACGCGGCCGCCGTAATGAGGAGGATAGTAGAATACATAGAGAAGATAAAGCCCAA
GTATGTAGTAATGATGGACGGCGGCTTCACCTACCCAACCTTCAGGTTCACCATGTACCCCACTATAGTCAAGATACTGG
GGAAGAAGCCGGAGTGGAAAGTCATACACATCACGGAGCTCTTGGCCATGCTGCTCAGAGAAGGGAAGATAGCATTCAAA
CAAGTTAACGAGCCCATAACGTGGCACGACCCCTGCCAGATGGGCAGACACTCCAGGGTGTTCGAGCCGCCCAGGGAGCT
GCTCAAGGCGGCGAGCAAGGGTTACAGGGACCTGCCCCACAACAGGGAGATGAACTACTGCTGCGGAGGAGGGGGAGGCA
TAGGCTGTATACTTAGAGAAGTGAGGGTTATGATGGGCCAGCTAGTGGGCCAAGAGATAAGGCTGCCGCCGGACGAGGAG
GAGTTCGAGAGGAGGATCGAGGAGCGCTTGAAGCTAGCAACCCGTAGGAAGGTGGACGACATAGCGAAGAGCGGCGCCAA
GCTGGTGCTAACCGCTTGTCCGGCGTGCATAGAGACCATACAGAGAGGGATAAATTGGCACGGCAAGGACTACGGCATAG
AAGACGTGCAAGTGAAGCACATATCCGAGTACTTGGTGGACAAGCTAATAGCCCCCGCTCCCAGCAAGCCTGCTCATTAA

Upstream 100 bases:

>100_bases
TGTACATACCGTTTAGTAAGTACTGGCACTTCGTTTTTGGGTACTGGTACGGCAAGCTCCACGAGTGGTATGACTTAGAC
GTGAAGAGGGGTGAGGCGAT

Downstream 100 bases:

>100_bases
CCTCTTTTTGCACACCTCACAAAACGCCGCCTCCTTCTCGTCCACCTCTAGTATTGAGTTAGAGAAGCTCATAACGCACC
TAGGGTTGGGGCAGTGGGGG

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSESMDFSRMMQMLMSQKTSIDEAIKKAMKKVDAVMIHYIEDCLNCGTCSPACPYFVAGPQYSPVNKAEELRKIYRREMT
ILGRLLGPLVGADKPKTEEDMKRLMDLVYACTNCGHCYYTCTVGIHSGTMIGLLKSILTEAGYVPTLLNLFEAIEVQNMH
MKIPGLKKVWEDALKEAQEKYGEIEFDKPNVDVFFLSWLTDAMMMREGFIATIGILNKLKEAGLITWTTWREPLGIRSPI
SVVIGRSENAAAVMRRIVEYIEKIKPKYVVMMDGGFTYPTFRFTMYPTIVKILGKKPEWKVIHITELLAMLLREGKIAFK
QVNEPITWHDPCQMGRHSRVFEPPRELLKAASKGYRDLPHNREMNYCCGGGGGIGCILREVRVMMGQLVGQEIRLPPDEE
EFERRIEERLKLATRRKVDDIAKSGAKLVLTACPACIETIQRGINWHGKDYGIEDVQVKHISEYLVDKLIAPAPSKPAH

Sequences:

>Translated_479_residues
MSESMDFSRMMQMLMSQKTSIDEAIKKAMKKVDAVMIHYIEDCLNCGTCSPACPYFVAGPQYSPVNKAEELRKIYRREMT
ILGRLLGPLVGADKPKTEEDMKRLMDLVYACTNCGHCYYTCTVGIHSGTMIGLLKSILTEAGYVPTLLNLFEAIEVQNMH
MKIPGLKKVWEDALKEAQEKYGEIEFDKPNVDVFFLSWLTDAMMMREGFIATIGILNKLKEAGLITWTTWREPLGIRSPI
SVVIGRSENAAAVMRRIVEYIEKIKPKYVVMMDGGFTYPTFRFTMYPTIVKILGKKPEWKVIHITELLAMLLREGKIAFK
QVNEPITWHDPCQMGRHSRVFEPPRELLKAASKGYRDLPHNREMNYCCGGGGGIGCILREVRVMMGQLVGQEIRLPPDEE
EFERRIEERLKLATRRKVDDIAKSGAKLVLTACPACIETIQRGINWHGKDYGIEDVQVKHISEYLVDKLIAPAPSKPAH
>Mature_478_residues
SESMDFSRMMQMLMSQKTSIDEAIKKAMKKVDAVMIHYIEDCLNCGTCSPACPYFVAGPQYSPVNKAEELRKIYRREMTI
LGRLLGPLVGADKPKTEEDMKRLMDLVYACTNCGHCYYTCTVGIHSGTMIGLLKSILTEAGYVPTLLNLFEAIEVQNMHM
KIPGLKKVWEDALKEAQEKYGEIEFDKPNVDVFFLSWLTDAMMMREGFIATIGILNKLKEAGLITWTTWREPLGIRSPIS
VVIGRSENAAAVMRRIVEYIEKIKPKYVVMMDGGFTYPTFRFTMYPTIVKILGKKPEWKVIHITELLAMLLREGKIAFKQ
VNEPITWHDPCQMGRHSRVFEPPRELLKAASKGYRDLPHNREMNYCCGGGGGIGCILREVRVMMGQLVGQEIRLPPDEEE
FERRIEERLKLATRRKVDDIAKSGAKLVLTACPACIETIQRGINWHGKDYGIEDVQVKHISEYLVDKLIAPAPSKPAH

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 54424; Mature: 54293

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESMDFSRMMQMLMSQKTSIDEAIKKAMKKVDAVMIHYIEDCLNCGTCSPACPYFVAGP
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
QYSPVNKAEELRKIYRREMTILGRLLGPLVGADKPKTEEDMKRLMDLVYACTNCGHCYYT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
CTVGIHSGTMIGLLKSILTEAGYVPTLLNLFEAIEVQNMHMKIPGLKKVWEDALKEAQEK
EEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHH
YGEIEFDKPNVDVFFLSWLTDAMMMREGFIATIGILNKLKEAGLITWTTWREPLGIRSPI
HCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCH
SVVIGRSENAAAVMRRIVEYIEKIKPKYVVMMDGGFTYPTFRFTMYPTIVKILGKKPEWK
HEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCE
VIHITELLAMLLREGKIAFKQVNEPITWHDPCQMGRHSRVFEPPRELLKAASKGYRDLPH
EEEHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCC
NREMNYCCGGGGGIGCILREVRVMMGQLVGQEIRLPPDEEEFERRIEERLKLATRRKVDD
CCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IAKSGAKLVLTACPACIETIQRGINWHGKDYGIEDVQVKHISEYLVDKLIAPAPSKPAH
HHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SESMDFSRMMQMLMSQKTSIDEAIKKAMKKVDAVMIHYIEDCLNCGTCSPACPYFVAGP
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
QYSPVNKAEELRKIYRREMTILGRLLGPLVGADKPKTEEDMKRLMDLVYACTNCGHCYYT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
CTVGIHSGTMIGLLKSILTEAGYVPTLLNLFEAIEVQNMHMKIPGLKKVWEDALKEAQEK
EEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHH
YGEIEFDKPNVDVFFLSWLTDAMMMREGFIATIGILNKLKEAGLITWTTWREPLGIRSPI
HCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCH
SVVIGRSENAAAVMRRIVEYIEKIKPKYVVMMDGGFTYPTFRFTMYPTIVKILGKKPEWK
HEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCE
VIHITELLAMLLREGKIAFKQVNEPITWHDPCQMGRHSRVFEPPRELLKAASKGYRDLPH
EEEHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCC
NREMNYCCGGGGGIGCILREVRVMMGQLVGQEIRLPPDEEEFERRIEERLKLATRRKVDD
CCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IAKSGAKLVLTACPACIETIQRGINWHGKDYGIEDVQVKHISEYLVDKLIAPAPSKPAH
HHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 8174566 [H]