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The map label for this gene is tbp [H]

Identifier: 156937779

GI number: 156937779

Start: 879702

End: 880325

Strand: Reverse

Name: tbp [H]

Synonym: Igni_0989

Alternate gene names: 156937779

Gene position: 880325-879702 (Counterclockwise)

Preceding gene: 156937780

Following gene: 156937777

Centisome position: 67.85

GC content: 50.0

Gene sequence:

>624_bases
TTGTCTCTCGACGCTGAAGCGAAGCCCAGTATAAAAATAGAAAACATCGTAGCCACGGTTTCCATAGACCAAAACATAGA
CCTAGAGAAAATTGAAAAGGAATTCGACAGCAACGTGGAATACGACCCGGACCAGTTCCCGGGCCTCATATTCCGGTTGG
AAGAGCCGAGGGTTACGGCCCTTATATTCAAGTCCGGTAAGATGGTGGTTACCGGCGCGAAGAGCACCCAAGAGTTAATA
ACAGCAGTTAAGAAGATATTCTACATCCTCAAGTCGAAAGGTATAGTGAGCGGCAAGGTAAGGCCGCGCATTCAGATACA
GAACATAGTGGCCTCCGCCAACTTGGGTGTGGAGGTCCACCTGGAGAAGGCGGCCTACTTGCTGGAGAACAGCATGTACG
AGCCGGAGCAGTTCCCGGGCCTCATATACCGACTGGACGAGCCTAGAGTGGTCTTGCTCTTGTTCTCCTCGGGTAAGATG
GTGGTTACCGGCGCGAAGAAGGAAGAAGAGGTTAGTAAGGCAGTAGAGAAAGTGTTCCAGAACTTAAAGGAGAAGGGCTG
TATAAGGGAGCCCGAGGTAGACCTAAGTGTAGAAGAAATGTTAGGCGAGGACGAAGAACTTTAA

Upstream 100 bases:

>100_bases
TCGAAAGCGCGCCCAAAGACTACATAGAGCCGTGGACCGGGATCTAAACGAGCAAAGAATATTTAAACCCTTTAAAAATC
CTTAAAAAGCGGGTCTCACT

Downstream 100 bases:

>100_bases
GAGCTTAGGAGTTCCCTCACTTTTTCCACTATTTGTTCCATCTCTTCCTCGCTCAGTTCCAAGTCTGGAACTACGCCTAA
CACCACCTTCAAGAAGTCCA

Product: TATA binding protein of transcription factor TFIID

Products: NA

Alternate protein names: Box A-binding protein; BAP; TATA sequence-binding protein; TBP; TATA-box factor [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSLDAEAKPSIKIENIVATVSIDQNIDLEKIEKEFDSNVEYDPDQFPGLIFRLEEPRVTALIFKSGKMVVTGAKSTQELI
TAVKKIFYILKSKGIVSGKVRPRIQIQNIVASANLGVEVHLEKAAYLLENSMYEPEQFPGLIYRLDEPRVVLLLFSSGKM
VVTGAKKEEEVSKAVEKVFQNLKEKGCIREPEVDLSVEEMLGEDEEL

Sequences:

>Translated_207_residues
MSLDAEAKPSIKIENIVATVSIDQNIDLEKIEKEFDSNVEYDPDQFPGLIFRLEEPRVTALIFKSGKMVVTGAKSTQELI
TAVKKIFYILKSKGIVSGKVRPRIQIQNIVASANLGVEVHLEKAAYLLENSMYEPEQFPGLIYRLDEPRVVLLLFSSGKM
VVTGAKKEEEVSKAVEKVFQNLKEKGCIREPEVDLSVEEMLGEDEEL
>Mature_206_residues
SLDAEAKPSIKIENIVATVSIDQNIDLEKIEKEFDSNVEYDPDQFPGLIFRLEEPRVTALIFKSGKMVVTGAKSTQELIT
AVKKIFYILKSKGIVSGKVRPRIQIQNIVASANLGVEVHLEKAAYLLENSMYEPEQFPGLIYRLDEPRVVLLLFSSGKMV
VTGAKKEEEVSKAVEKVFQNLKEKGCIREPEVDLSVEEMLGEDEEL

Specific function: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation [H]

COG id: COG2101

COG function: function code K; TATA-box binding protein (TBP), component of TFIID and TFIIIB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TBP family [H]

Homologues:

Organism=Homo sapiens, GI39930602, Length=173, Percent_Identity=43.3526011560694, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI285026520, Length=173, Percent_Identity=42.7745664739884, Blast_Score=133, Evalue=9e-32,
Organism=Homo sapiens, GI4507379, Length=173, Percent_Identity=42.7745664739884, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI4759234, Length=180, Percent_Identity=30.5555555555556, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555358, Length=176, Percent_Identity=42.6136363636364, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI193202769, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509361, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320996, Length=173, Percent_Identity=44.5086705202312, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17647997, Length=183, Percent_Identity=44.2622950819672, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI17136834, Length=174, Percent_Identity=40.2298850574713, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012295
- InterPro:   IPR000814
- InterPro:   IPR012294 [H]

Pfam domain/function: PF00352 TBP [H]

EC number: NA

Molecular weight: Translated: 23231; Mature: 23100

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00351 TFIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDAEAKPSIKIENIVATVSIDQNIDLEKIEKEFDSNVEYDPDQFPGLIFRLEEPRVTA
CCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEE
LIFKSGKMVVTGAKSTQELITAVKKIFYILKSKGIVSGKVRPRIQIQNIVASANLGVEVH
EEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECCCCCEEEE
LEKAAYLLENSMYEPEQFPGLIYRLDEPRVVLLLFSSGKMVVTGAKKEEEVSKAVEKVFQ
HHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHH
NLKEKGCIREPEVDLSVEEMLGEDEEL
HHHHCCCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SLDAEAKPSIKIENIVATVSIDQNIDLEKIEKEFDSNVEYDPDQFPGLIFRLEEPRVTA
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEE
LIFKSGKMVVTGAKSTQELITAVKKIFYILKSKGIVSGKVRPRIQIQNIVASANLGVEVH
EEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECCCCCEEEE
LEKAAYLLENSMYEPEQFPGLIYRLDEPRVVLLLFSSGKMVVTGAKKEEEVSKAVEKVFQ
HHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHH
NLKEKGCIREPEVDLSVEEMLGEDEEL
HHHHCCCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7784182 [H]