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The map label for this gene is trpF [H]

Identifier: 156937717

GI number: 156937717

Start: 820252

End: 820836

Strand: Reverse

Name: trpF [H]

Synonym: Igni_0926

Alternate gene names: 156937717

Gene position: 820836-820252 (Counterclockwise)

Preceding gene: 156937719

Following gene: 156937716

Centisome position: 63.26

GC content: 63.76

Gene sequence:

>585_bases
TTGCCGGAGCTAAAGGTGTGTGGGGTCACGAACCCCGAGGACGCCGAGGTGGCCGTAGAGGCCGGGGCGAGCTACGTGGG
CGTGATAATAGACGCCCCCTCCCCGAGGCTCGTGGGGCCGGAGGCCGCGCGGGACGTGGCCTCGGTACTCCCCTCCCACG
TAAAGCCCGTCGGGGTGGTGGACGCGAGAAAGCCCTTGGACTTGGACAAGGTGCTTAACTCGGGAGTTAAGGTGGTTCAG
CTCCACTGGGGGGACGAGTCCTCCTTCTTGAGGGCGAAGCTCCTCCTAGAGGGCTACGGCGTCTCGGTCGCGGTGGCCCC
GCTGAGGGCAACCCCCTTCAAGTACGCGGGGGCCGAATACGTCTTGTGGGACAAGAAGAGTTTCGAAGAGAAGTTCGTCT
CGTGGGGCGCTCGGTGGACCAAGGTGGGGGTCGCCGGCAAGGTGACGCCAGAGAACGTCAAGGAGGTCGTGGCCCTCTTC
AAGCCCGACTTAATAGACGTCAGCAGCGGGGTAGAGGTTAAACCCGGCGTCAAGGACCCCGAGAAGGTAATGAAGGTAGC
AGAGGTGATCGGCCTCGCGCTGTGA

Upstream 100 bases:

>100_bases
CAAGGCGAAGGGTTCGCCGCACTCGGCTACGAGCGATATCCCGCCGAAGCCCGTTGCCACAGCCTTTAGCCTCAAAGCGT
CGCTTGCCGGAGGTGAGGGC

Downstream 100 bases:

>100_bases
GAGGCTCCCGCTCTCCTCGGTGCCCAAGCCCGCGGAGCTCTTCTCGTCCTTGGAAGGTCCTTCCTTAATATTGGAGAGCG
CTGCCGGCGGCGAGACCAAG

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MPELKVCGVTNPEDAEVAVEAGASYVGVIIDAPSPRLVGPEAARDVASVLPSHVKPVGVVDARKPLDLDKVLNSGVKVVQ
LHWGDESSFLRAKLLLEGYGVSVAVAPLRATPFKYAGAEYVLWDKKSFEEKFVSWGARWTKVGVAGKVTPENVKEVVALF
KPDLIDVSSGVEVKPGVKDPEKVMKVAEVIGLAL

Sequences:

>Translated_194_residues
MPELKVCGVTNPEDAEVAVEAGASYVGVIIDAPSPRLVGPEAARDVASVLPSHVKPVGVVDARKPLDLDKVLNSGVKVVQ
LHWGDESSFLRAKLLLEGYGVSVAVAPLRATPFKYAGAEYVLWDKKSFEEKFVSWGARWTKVGVAGKVTPENVKEVVALF
KPDLIDVSSGVEVKPGVKDPEKVMKVAEVIGLAL
>Mature_193_residues
PELKVCGVTNPEDAEVAVEAGASYVGVIIDAPSPRLVGPEAARDVASVLPSHVKPVGVVDARKPLDLDKVLNSGVKVVQL
HWGDESSFLRAKLLLEGYGVSVAVAPLRATPFKYAGAEYVLWDKKSFEEKFVSWGARWTKVGVAGKVTPENVKEVVALFK
PDLIDVSSGVEVKPGVKDPEKVMKVAEVIGLAL

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=202, Percent_Identity=30.6930693069307, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 20698; Mature: 20567

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELKVCGVTNPEDAEVAVEAGASYVGVIIDAPSPRLVGPEAARDVASVLPSHVKPVGVV
CCCCEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEE
DARKPLDLDKVLNSGVKVVQLHWGDESSFLRAKLLLEGYGVSVAVAPLRATPFKYAGAEY
CCCCCCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEE
VLWDKKSFEEKFVSWGARWTKVGVAGKVTPENVKEVVALFKPDLIDVSSGVEVKPGVKDP
EEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCEECCCCCCH
EKVMKVAEVIGLAL
HHHHHHHHHHHCCC
>Mature Secondary Structure 
PELKVCGVTNPEDAEVAVEAGASYVGVIIDAPSPRLVGPEAARDVASVLPSHVKPVGVV
CCCEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEE
DARKPLDLDKVLNSGVKVVQLHWGDESSFLRAKLLLEGYGVSVAVAPLRATPFKYAGAEY
CCCCCCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEE
VLWDKKSFEEKFVSWGARWTKVGVAGKVTPENVKEVVALFKPDLIDVSSGVEVKPGVKDP
EEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCEECCCCCCH
EKVMKVAEVIGLAL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA