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The map label for this gene is 156937667

Identifier: 156937667

GI number: 156937667

Start: 774827

End: 776371

Strand: Direct

Name: 156937667

Synonym: Igni_0874

Alternate gene names: NA

Gene position: 774827-776371 (Clockwise)

Preceding gene: 156937666

Following gene: 156937668

Centisome position: 59.72

GC content: 56.96

Gene sequence:

>1545_bases
ATGAAGAGGGTACTCGTAGTAACGAGTAAGAGGTTGGAGAGCGCCGTCAAGGCCATGCTCAAGCCCCCTGAGGGCTACTC
CGTGGAGGTCTGGGGGCTTCCGGTGGACGTGGTGGCCCTCCTTAGGCCGAGGAGCTTGAAGGAGTTGTTGAGGTTAGAGG
AGAGGAAGAGGGGTACCCCCCTTAGCTCCTTCGACTACGTCTTGGTCTCCGGAGCCATTCCCGGCGACTTGAGCGAGGTC
GGCGAGGGGCTGGGCGCGAAGATCTATAAAGGGACCAAGACCTTGAGTGACTTCGAAGTTATGATTAAGAACTTAAACGC
GGTGGAGAAGTACTTGTCCCCCTCGGAGCCCCTCGACGAGGTGTTGAGCGAGCTGAAGTTGAAGGAGCTGAGGGAGTTCA
TAGAGACCTACGTCCCGGAGGAGTACGTCGTCGTGGGGGGCTTGAAGGTCCCGTTGAGGCCCCCGCCCGCCTTGTTGGCG
GCGGAGGTGTTGGACAACGAAGACGTGGAGTCCCAGCTCCTAAAGGCCTCCGAAGTGGCCGACATGGTGATAGTCGGCTC
CACCTCCACCTCTCCGGACCCCGAGAAGGCCCGGAGGCTGGTCGAGCTCGCCAGGAGGTACTTCCACACGGTAGGCTTCG
ACAGCATGTTTGTAAAGGAGATGAAAGCTGTGGACGCGGACCTCATACTGTCTTTGGAGAGGTCGAAGCTCGAGGAGCTC
GAGCCCTCAGACGACAAGGCCTTCGTCGTAATCCCGGGGGACGTGAAGAGGAACTACTGGCCAAATAACGCCGAGGAGAA
GGTAGAGTCACTCTTGTCTAACCTGAAGGTCGCCCAAGAGCGCGGCTTCGAGAAGGTTATAGTGGACCCCGTGCTCTCTC
CCTTCCCGCATACTTTGGAAAGCTTCGTGGCCTTGAGAGAAATCTCAAAGAAAGTTAAGGCTCCCATAATGTTAGGCTTG
AGCAACTTCGTGGAGCTGGTGGACGCGGACAGCCCCGGACAGCTGGCCGCTCTGACCTCCTTGGCCCTAGAGGGAGGGGC
CTCGTTGCTCATGGTAACTGAACACAGCGACAAGTGTAAGGGCGCGTGGTCGGAAGCGAAGGCGGCCGCTATAATGACCT
CATACGCCTTGTACAAGTCAACCCTGCCCAAAGACTTAGGCTTGGATTTGTTAATACTTAAGGAAAAAAGGATAAGGAGA
GAGAAAGTAAGCGTGGAGAACAAGAGAGAGATAGAGGTGAGGGACGTAAAGTTCAAGTTGGAGAATACTGTAGTTAGGAT
TTGGGTAGAGGGCGACGAGGTGAGGGCCTCCGTGGAGCCCCACGGCGTGTGGCTCAGGGGCGACGCCTACTTGATAGGAA
AAACCATAATAGCAGAGGGGCTGGTGAAGGAACCGTCACACGCCCTCTACTTAGGGTGGGAGCTCCAGAAGGCCCACTTG
GCGGCCAAGCTCAACAAGAGCTACGTACAAGACGAGGAGCTGCGCTTCGAACCTCCAAGGGAGAAACTTAGGGGGCTCCG
AGAAGGAGAGGGGGACGCGAGTTGA

Upstream 100 bases:

>100_bases
GACTAGGGTGGGCGCCCGCTCTTGGATTTACCCCGGCTGCGTAGTGAGGGGCGACGTCCCGGACGGGGCTAGGTACAAGT
GCTGAGGCGGTGTTTAGGAA

Downstream 100 bases:

>100_bases
AGGTAAGGGTGGGCCACAGCCCAGACCCGGACGACGCCTTCATGTTCTACCCAATAAAGTTCAAGAAGATAGACTTGAGA
GGCTATGAAGTGGAAGAGGT

Product: dihydropteroate synthase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKRVLVVTSKRLESAVKAMLKPPEGYSVEVWGLPVDVVALLRPRSLKELLRLEERKRGTPLSSFDYVLVSGAIPGDLSEV
GEGLGAKIYKGTKTLSDFEVMIKNLNAVEKYLSPSEPLDEVLSELKLKELREFIETYVPEEYVVVGGLKVPLRPPPALLA
AEVLDNEDVESQLLKASEVADMVIVGSTSTSPDPEKARRLVELARRYFHTVGFDSMFVKEMKAVDADLILSLERSKLEEL
EPSDDKAFVVIPGDVKRNYWPNNAEEKVESLLSNLKVAQERGFEKVIVDPVLSPFPHTLESFVALREISKKVKAPIMLGL
SNFVELVDADSPGQLAALTSLALEGGASLLMVTEHSDKCKGAWSEAKAAAIMTSYALYKSTLPKDLGLDLLILKEKRIRR
EKVSVENKREIEVRDVKFKLENTVVRIWVEGDEVRASVEPHGVWLRGDAYLIGKTIIAEGLVKEPSHALYLGWELQKAHL
AAKLNKSYVQDEELRFEPPREKLRGLREGEGDAS

Sequences:

>Translated_514_residues
MKRVLVVTSKRLESAVKAMLKPPEGYSVEVWGLPVDVVALLRPRSLKELLRLEERKRGTPLSSFDYVLVSGAIPGDLSEV
GEGLGAKIYKGTKTLSDFEVMIKNLNAVEKYLSPSEPLDEVLSELKLKELREFIETYVPEEYVVVGGLKVPLRPPPALLA
AEVLDNEDVESQLLKASEVADMVIVGSTSTSPDPEKARRLVELARRYFHTVGFDSMFVKEMKAVDADLILSLERSKLEEL
EPSDDKAFVVIPGDVKRNYWPNNAEEKVESLLSNLKVAQERGFEKVIVDPVLSPFPHTLESFVALREISKKVKAPIMLGL
SNFVELVDADSPGQLAALTSLALEGGASLLMVTEHSDKCKGAWSEAKAAAIMTSYALYKSTLPKDLGLDLLILKEKRIRR
EKVSVENKREIEVRDVKFKLENTVVRIWVEGDEVRASVEPHGVWLRGDAYLIGKTIIAEGLVKEPSHALYLGWELQKAHL
AAKLNKSYVQDEELRFEPPREKLRGLREGEGDAS
>Mature_514_residues
MKRVLVVTSKRLESAVKAMLKPPEGYSVEVWGLPVDVVALLRPRSLKELLRLEERKRGTPLSSFDYVLVSGAIPGDLSEV
GEGLGAKIYKGTKTLSDFEVMIKNLNAVEKYLSPSEPLDEVLSELKLKELREFIETYVPEEYVVVGGLKVPLRPPPALLA
AEVLDNEDVESQLLKASEVADMVIVGSTSTSPDPEKARRLVELARRYFHTVGFDSMFVKEMKAVDADLILSLERSKLEEL
EPSDDKAFVVIPGDVKRNYWPNNAEEKVESLLSNLKVAQERGFEKVIVDPVLSPFPHTLESFVALREISKKVKAPIMLGL
SNFVELVDADSPGQLAALTSLALEGGASLLMVTEHSDKCKGAWSEAKAAAIMTSYALYKSTLPKDLGLDLLILKEKRIRR
EKVSVENKREIEVRDVKFKLENTVVRIWVEGDEVRASVEPHGVWLRGDAYLIGKTIIAEGLVKEPSHALYLGWELQKAHL
AAKLNKSYVQDEELRFEPPREKLRGLREGEGDAS

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: NA

Molecular weight: Translated: 57250; Mature: 57250

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLVVTSKRLESAVKAMLKPPEGYSVEVWGLPVDVVALLRPRSLKELLRLEERKRGTP
CCEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHHHCCCC
LSSFDYVLVSGAIPGDLSEVGEGLGAKIYKGTKTLSDFEVMIKNLNAVEKYLSPSEPLDE
CCCCCEEEEECCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
VLSELKLKELREFIETYVPEEYVVVGGLKVPLRPPPALLAAEVLDNEDVESQLLKASEVA
HHHHHHHHHHHHHHHHHCCCCEEEECCEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHC
DMVIVGSTSTSPDPEKARRLVELARRYFHTVGFDSMFVKEMKAVDADLILSLERSKLEEL
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHC
EPSDDKAFVVIPGDVKRNYWPNNAEEKVESLLSNLKVAQERGFEKVIVDPVLSPFPHTLE
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHH
SFVALREISKKVKAPIMLGLSNFVELVDADSPGQLAALTSLALEGGASLLMVTEHSDKCK
HHHHHHHHHHHHCCCHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCC
GAWSEAKAAAIMTSYALYKSTLPKDLGLDLLILKEKRIRREKVSVENKREIEVRDVKFKL
CCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECHHHHHHHHCCCCCCCCEEEEEEEEEE
ENTVVRIWVEGDEVRASVEPHGVWLRGDAYLIGKTIIAEGLVKEPSHALYLGWELQKAHL
ECEEEEEEEECCCEEEECCCCCEEEECCEEEEHHHHHHHHHHCCCCCEEEEEEEHHHHHH
AAKLNKSYVQDEELRFEPPREKLRGLREGEGDAS
HHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKRVLVVTSKRLESAVKAMLKPPEGYSVEVWGLPVDVVALLRPRSLKELLRLEERKRGTP
CCEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHHHCCCC
LSSFDYVLVSGAIPGDLSEVGEGLGAKIYKGTKTLSDFEVMIKNLNAVEKYLSPSEPLDE
CCCCCEEEEECCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
VLSELKLKELREFIETYVPEEYVVVGGLKVPLRPPPALLAAEVLDNEDVESQLLKASEVA
HHHHHHHHHHHHHHHHHCCCCEEEECCEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHC
DMVIVGSTSTSPDPEKARRLVELARRYFHTVGFDSMFVKEMKAVDADLILSLERSKLEEL
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHC
EPSDDKAFVVIPGDVKRNYWPNNAEEKVESLLSNLKVAQERGFEKVIVDPVLSPFPHTLE
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHH
SFVALREISKKVKAPIMLGLSNFVELVDADSPGQLAALTSLALEGGASLLMVTEHSDKCK
HHHHHHHHHHHHCCCHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCC
GAWSEAKAAAIMTSYALYKSTLPKDLGLDLLILKEKRIRREKVSVENKREIEVRDVKFKL
CCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECHHHHHHHHCCCCCCCCEEEEEEEEEE
ENTVVRIWVEGDEVRASVEPHGVWLRGDAYLIGKTIIAEGLVKEPSHALYLGWELQKAHL
ECEEEEEEEECCCEEEECCCCCEEEECCEEEEHHHHHHHHHHCCCCCEEEEEEEHHHHHH
AAKLNKSYVQDEELRFEPPREKLRGLREGEGDAS
HHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]