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The map label for this gene is pcn [H]

Identifier: 156937647

GI number: 156937647

Start: 757433

End: 758170

Strand: Direct

Name: pcn [H]

Synonym: Igni_0854

Alternate gene names: 156937647

Gene position: 757433-758170 (Clockwise)

Preceding gene: 156937646

Following gene: 156937648

Centisome position: 58.37

GC content: 53.39

Gene sequence:

>738_bases
TTGAAGCTCACCTTCTTCGACGCCAGAGTATGGAAGTACGTGATCTCCGGGGTTTCTAAAGTAGTCAAAGAAACTGTAGC
CCATGTGAACGAGGAGGGCTTCAGGATAAAAACTATGGACGAGTCTAAAGTGGTGCTAATAGACTTCATGATACCGTCCT
CCAGCTTCGAGGTATTTGAGGTTGAGAGCGACGTCAGCTTCGGTATTAATATGGAGGACTTGGCCAAAGTTATGAGGAGG
GCGACGAAGGAGGACAAGTTAAGCATAGAAGTGGGGGAGAACAGCTATTCTATAATCTTCGAGGGCCACGGCTTGAGGAA
GTTCACCCTACCTCAGTTGGAGGTGTACGAGGAAGAGTTGCCCGAGGTGGACCTCGAGCTCCCCGCTAGGGTCGAGATAA
CCTCCGACTCTTACAGAGAGCTGGTAAAGGACCTCGAACCCATAGCCGACACAGTGACCTTTAACTTGGAGCCGGGAACC
TTAAGGGTTGAGGCGACCAGCGACTTGGGCTACGCGGAAGTGATAATCTCGGAGGACTCCGGCGTACTCTTGGACTACCA
AGTGCCGGAGAGCGTTAAGTCCTCCTACGGCCTCGAGTACTTGACGTACGTGAGCTCGGTGTCCCAAGTGGCGGACAAGG
TCGCGCTGGAGATAGGCAACGACATGCCCCTCCGCGCAACCTTCGAGATAGGAGAGGGGGGCAAGCTTGTCTACTTACTC
GCGCCGCGTGTCGAATAA

Upstream 100 bases:

>100_bases
GGTGGAGCTGGCCGGGGCGCCGGTGAGGGTGCCCGCGGACCCCTCCTACATGGTGTAACTCTTTCTTACCTCTCTTCGGA
ACGCCCCCGGGGCGAATTGG

Downstream 100 bases:

>100_bases
GCTGCACTTAATGATACTCGACTATTACAAGGAAGCTAGGTTTGAGGTGCCGGAGGACTTAAGCCAGAGGGAGGTGGCGG
TCCAAACAGTCGACGGCGGG

Product: proliferating cell nuclear antigen PcnA

Products: NA

Alternate protein names: Proliferating cell nuclear antigen homolog; PCNA [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKLTFFDARVWKYVISGVSKVVKETVAHVNEEGFRIKTMDESKVVLIDFMIPSSSFEVFEVESDVSFGINMEDLAKVMRR
ATKEDKLSIEVGENSYSIIFEGHGLRKFTLPQLEVYEEELPEVDLELPARVEITSDSYRELVKDLEPIADTVTFNLEPGT
LRVEATSDLGYAEVIISEDSGVLLDYQVPESVKSSYGLEYLTYVSSVSQVADKVALEIGNDMPLRATFEIGEGGKLVYLL
APRVE

Sequences:

>Translated_245_residues
MKLTFFDARVWKYVISGVSKVVKETVAHVNEEGFRIKTMDESKVVLIDFMIPSSSFEVFEVESDVSFGINMEDLAKVMRR
ATKEDKLSIEVGENSYSIIFEGHGLRKFTLPQLEVYEEELPEVDLELPARVEITSDSYRELVKDLEPIADTVTFNLEPGT
LRVEATSDLGYAEVIISEDSGVLLDYQVPESVKSSYGLEYLTYVSSVSQVADKVALEIGNDMPLRATFEIGEGGKLVYLL
APRVE
>Mature_245_residues
MKLTFFDARVWKYVISGVSKVVKETVAHVNEEGFRIKTMDESKVVLIDFMIPSSSFEVFEVESDVSFGINMEDLAKVMRR
ATKEDKLSIEVGENSYSIIFEGHGLRKFTLPQLEVYEEELPEVDLELPARVEITSDSYRELVKDLEPIADTVTFNLEPGT
LRVEATSDLGYAEVIISEDSGVLLDYQVPESVKSSYGLEYLTYVSSVSQVADKVALEIGNDMPLRATFEIGEGGKLVYLL
APRVE

Specific function: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication [H]

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PCNA family [H]

Homologues:

Organism=Homo sapiens, GI33239451, Length=258, Percent_Identity=23.6434108527132, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI4505641, Length=258, Percent_Identity=23.6434108527132, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71995072, Length=221, Percent_Identity=20.8144796380091, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319564, Length=253, Percent_Identity=22.5296442687747, Blast_Score=82, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24585303, Length=243, Percent_Identity=23.8683127572016, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17136790, Length=252, Percent_Identity=22.6190476190476, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45552759, Length=252, Percent_Identity=22.6190476190476, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000730
- InterPro:   IPR022649
- InterPro:   IPR022648 [H]

Pfam domain/function: PF02747 PCNA_C; PF00705 PCNA_N [H]

EC number: NA

Molecular weight: Translated: 27486; Mature: 27486

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTFFDARVWKYVISGVSKVVKETVAHVNEEGFRIKTMDESKVVLIDFMIPSSSFEVFE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCEEEE
VESDVSFGINMEDLAKVMRRATKEDKLSIEVGENSYSIIFEGHGLRKFTLPQLEVYEEEL
ECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCEEECCCHHHHHHHHC
PEVDLELPARVEITSDSYRELVKDLEPIADTVTFNLEPGTLRVEATSDLGYAEVIISEDS
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCEEEEEEECCC
GVLLDYQVPESVKSSYGLEYLTYVSSVSQVADKVALEIGNDMPLRATFEIGEGGKLVYLL
CEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEE
APRVE
CCCCC
>Mature Secondary Structure
MKLTFFDARVWKYVISGVSKVVKETVAHVNEEGFRIKTMDESKVVLIDFMIPSSSFEVFE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCEEEE
VESDVSFGINMEDLAKVMRRATKEDKLSIEVGENSYSIIFEGHGLRKFTLPQLEVYEEEL
ECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCEEECCCHHHHHHHHC
PEVDLELPARVEITSDSYRELVKDLEPIADTVTFNLEPGTLRVEATSDLGYAEVIISEDS
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCEEEEEEECCC
GVLLDYQVPESVKSSYGLEYLTYVSSVSQVADKVALEIGNDMPLRATFEIGEGGKLVYLL
CEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEE
APRVE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA