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The map label for this gene is eif1a [H]

Identifier: 156937469

GI number: 156937469

Start: 609778

End: 610176

Strand: Reverse

Name: eif1a [H]

Synonym: Igni_0676

Alternate gene names: 156937469

Gene position: 610176-609778 (Counterclockwise)

Preceding gene: 156937470

Following gene: 156937468

Centisome position: 47.03

GC content: 52.88

Gene sequence:

>399_bases
TTGGCAAAGAGGAAAGGGACTCGAAGCGAGAAGAGTAAAGAAGTGGTGTTACCGGGCGAAGGCGAGGTACTCTGCGTAGT
AGAGAGGATAGTGGGGGCGGACCACGCGCTGATACGCTGTTTGGACAACCCCGAGTTGGTCAGGGACGGCAGGATCCCGG
GCAAGTTGAGGAGGAGGGTCTGGATAAGGGAAGGAGATATAGTGATTGCAACCGTTTGGGACTTCCAGCCCAAAAAGGCG
GACATAGTGTACAGATATTCTCGAGACGAGCTAAAGAGGCTGATAGTAAAAGGCTTGTTGCCTAAGGAGATAGCCGAACT
CGCGGGCATAACAGAAGAAGAAATAGCCTTGACTGCCCAACAAATGGCACAAGAAGAAGCGGAGGGTGAGGAGGCGTGA

Upstream 100 bases:

>100_bases
GACATAGTTCAGATAAACACCAAAATAGTCAAGCAGTGAAAGGTCCGAGCCCACTGAGGCACATTTAACCTTCACTCCAC
GTCCTCTTAGTGGTGTCACG

Downstream 100 bases:

>100_bases
GCGAGGAGGAGGTTACCAAGGCTGAGAAGGTAGAGGACGTCATGAAAAAAGTAGAGGAAGAAGTCAAGGCCCCCCAAAAG
GAAGAAGAGGTAGAAGAACA

Product: translation initiation factor 1A (aeIF-1A)

Products: NA

Alternate protein names: aIF-1A [H]

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MAKRKGTRSEKSKEVVLPGEGEVLCVVERIVGADHALIRCLDNPELVRDGRIPGKLRRRVWIREGDIVIATVWDFQPKKA
DIVYRYSRDELKRLIVKGLLPKEIAELAGITEEEIALTAQQMAQEEAEGEEA

Sequences:

>Translated_132_residues
MAKRKGTRSEKSKEVVLPGEGEVLCVVERIVGADHALIRCLDNPELVRDGRIPGKLRRRVWIREGDIVIATVWDFQPKKA
DIVYRYSRDELKRLIVKGLLPKEIAELAGITEEEIALTAQQMAQEEAEGEEA
>Mature_131_residues
AKRKGTRSEKSKEVVLPGEGEVLCVVERIVGADHALIRCLDNPELVRDGRIPGKLRRRVWIREGDIVIATVWDFQPKKAD
IVYRYSRDELKRLIVKGLLPKEIAELAGITEEEIALTAQQMAQEEAEGEEA

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540984, Length=102, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323916, Length=89, Percent_Identity=32.5842696629214, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- ProDom:   PD005579 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 14905; Mature: 14774

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRKGTRSEKSKEVVLPGEGEVLCVVERIVGADHALIRCLDNPELVRDGRIPGKLRRRV
CCCCCCCCCCCCCEEEECCCCCEEEEEHHHHCCCHHEEEECCCCCEEECCCCCHHHHHEE
WIREGDIVIATVWDFQPKKADIVYRYSRDELKRLIVKGLLPKEIAELAGITEEEIALTAQ
EEECCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
QMAQEEAEGEEA
HHHHHHCCCCCC
>Mature Secondary Structure 
AKRKGTRSEKSKEVVLPGEGEVLCVVERIVGADHALIRCLDNPELVRDGRIPGKLRRRV
CCCCCCCCCCCCEEEECCCCCEEEEEHHHHCCCHHEEEECCCCCEEECCCCCHHHHHEE
WIREGDIVIATVWDFQPKKADIVYRYSRDELKRLIVKGLLPKEIAELAGITEEEIALTAQ
EEECCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
QMAQEEAEGEEA
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA