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The map label for this gene is wecB [H]

Identifier: 156937416

GI number: 156937416

Start: 559263

End: 560348

Strand: Direct

Name: wecB [H]

Synonym: Igni_0623

Alternate gene names: 156937416

Gene position: 559263-560348 (Clockwise)

Preceding gene: 156937415

Following gene: 156937417

Centisome position: 43.1

GC content: 55.99

Gene sequence:

>1086_bases
TTGATAGCCGTGGTCGTGGGCACCAGGCCAGAAATAATAAAGATGGCGCCGGTGGTCCTCGAGCTCGAGAGCAGAGGAAT
AGACTACACCTTCGTTCACACCGGCCAACACTACGACTACGAAATGTCGAAGATTTTCATAGAGGAGTTGGGGCTGCCGG
AGCCCCACTTCAGCTTCGAGTTGAAGGGCTCCACCCCGGGAGAGCAAATAGGCGAAATGATAATCCACTTGGACAAAATT
TCGCAAGAGAGGAAGCCTAAGGTGGTCGCCGTCCAAGGCGACACCAACAGCATGGTGGCAGCGGCGATCGCGGCGCTGAA
GGTCGGGGCGGAGGTCGCCCACGTGGAGGCGGGGCTGCGGAGCTACGACTGGAGGATGCCAGAAGAGCACAACAGGAGGA
TGATAGACCACGTGTCCAAATACCTCTTCGCCCCCACGGAAGACGCGAAGAGGAACTTGGAGGAGGAGATGGTTTACGGA
GAGATTTACGTAACCGGCAACACAGTCATCGACGCGTTAGACAGATACATGGGCTTGGCCGAAGAGAGGTCGAAGGAGGT
GTTAGAAAAGGTACCCTTCGACGAGTTCGGCGTGGTTACCTTCCACCGCGCCGAGAACGTCGACAACCCACAAACGCTTA
AGGACTTCGTTAGGATACTGGAGAGGTCGCCCATACCCTTGGTATACCCAGTTCACCCCAGGACTAGGAAGAGGTTGCTC
GAGTTCGGCTTGTGGGACAGAGTAAAGAGAATACCTCACTTGATGATCACTGAGCCTTTGGGTTACCTAGAATTCATAGG
CCTGTTGAAGAACTCGAAGATAGTCTTGTCCGACTCCGGAGGGTTGCAAGAAGAAGTCACCCACCCCAAGATACGCAAGC
GGATAATCGTTCTGAGGACCTCAACCGAGAGGCCCGAGGCCATAAAGAGCGGGTTCGCCTACGTAGTGGGCACCAACCCG
GTAGTTGTGCTGGCTACCTTGGAGAGGGCCTTGAACGAGGGCGCCCCGCTCCCGGAGGCATCGCCTTTTGGGGACGGCAA
AGCTGGTAAGAGGATAGTGGACGTCTTGGAGAGGGTCGGGTCGTGA

Upstream 100 bases:

>100_bases
AGGTAGTTAAAGAGAAGAAAGTGTTGGACGGCAGGAACGTGGTACCTAAGGAAGAAGTGTTGAAATTCGGGTTCGTCTAC
AAGGCGTTGGGCGTGGGCAC

Downstream 100 bases:

>100_bases
AGGTGTGCATGCGGGTGGTAAAGGTCGAGGGCGAGTGCGCCGCCGGCTACGAGGTCGGGGACGAAATATGCTTCGAAGGG
TTTAGGCTGGTCTCCTTTAC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MIAVVVGTRPEIIKMAPVVLELESRGIDYTFVHTGQHYDYEMSKIFIEELGLPEPHFSFELKGSTPGEQIGEMIIHLDKI
SQERKPKVVAVQGDTNSMVAAAIAALKVGAEVAHVEAGLRSYDWRMPEEHNRRMIDHVSKYLFAPTEDAKRNLEEEMVYG
EIYVTGNTVIDALDRYMGLAEERSKEVLEKVPFDEFGVVTFHRAENVDNPQTLKDFVRILERSPIPLVYPVHPRTRKRLL
EFGLWDRVKRIPHLMITEPLGYLEFIGLLKNSKIVLSDSGGLQEEVTHPKIRKRIIVLRTSTERPEAIKSGFAYVVGTNP
VVVLATLERALNEGAPLPEASPFGDGKAGKRIVDVLERVGS

Sequences:

>Translated_361_residues
MIAVVVGTRPEIIKMAPVVLELESRGIDYTFVHTGQHYDYEMSKIFIEELGLPEPHFSFELKGSTPGEQIGEMIIHLDKI
SQERKPKVVAVQGDTNSMVAAAIAALKVGAEVAHVEAGLRSYDWRMPEEHNRRMIDHVSKYLFAPTEDAKRNLEEEMVYG
EIYVTGNTVIDALDRYMGLAEERSKEVLEKVPFDEFGVVTFHRAENVDNPQTLKDFVRILERSPIPLVYPVHPRTRKRLL
EFGLWDRVKRIPHLMITEPLGYLEFIGLLKNSKIVLSDSGGLQEEVTHPKIRKRIIVLRTSTERPEAIKSGFAYVVGTNP
VVVLATLERALNEGAPLPEASPFGDGKAGKRIVDVLERVGS
>Mature_361_residues
MIAVVVGTRPEIIKMAPVVLELESRGIDYTFVHTGQHYDYEMSKIFIEELGLPEPHFSFELKGSTPGEQIGEMIIHLDKI
SQERKPKVVAVQGDTNSMVAAAIAALKVGAEVAHVEAGLRSYDWRMPEEHNRRMIDHVSKYLFAPTEDAKRNLEEEMVYG
EIYVTGNTVIDALDRYMGLAEERSKEVLEKVPFDEFGVVTFHRAENVDNPQTLKDFVRILERSPIPLVYPVHPRTRKRLL
EFGLWDRVKRIPHLMITEPLGYLEFIGLLKNSKIVLSDSGGLQEEVTHPKIRKRIIVLRTSTERPEAIKSGFAYVVGTNP
VVVLATLERALNEGAPLPEASPFGDGKAGKRIVDVLERVGS

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=387, Percent_Identity=34.3669250645995, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40631; Mature: 40631

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVVVGTRPEIIKMAPVVLELESRGIDYTFVHTGQHYDYEMSKIFIEELGLPEPHFSFE
CEEEEECCCCCHHHHCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
LKGSTPGEQIGEMIIHLDKISQERKPKVVAVQGDTNSMVAAAIAALKVGAEVAHVEAGLR
ECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHH
SYDWRMPEEHNRRMIDHVSKYLFAPTEDAKRNLEEEMVYGEIYVTGNTVIDALDRYMGLA
HCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCHHHHEEEEEEEEECCHHHHHHHHHHCHH
EERSKEVLEKVPFDEFGVVTFHRAENVDNPQTLKDFVRILERSPIPLVYPVHPRTRKRLL
HHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
EFGLWDRVKRIPHLMITEPLGYLEFIGLLKNSKIVLSDSGGLQEEVTHPKIRKRIIVLRT
HHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCHHHHCCHHHHCEEEEEEE
STERPEAIKSGFAYVVGTNPVVVLATLERALNEGAPLPEASPFGDGKAGKRIVDVLERVG
CCCCCHHHHCCCEEEECCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHC
S
C
>Mature Secondary Structure
MIAVVVGTRPEIIKMAPVVLELESRGIDYTFVHTGQHYDYEMSKIFIEELGLPEPHFSFE
CEEEEECCCCCHHHHCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
LKGSTPGEQIGEMIIHLDKISQERKPKVVAVQGDTNSMVAAAIAALKVGAEVAHVEAGLR
ECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHH
SYDWRMPEEHNRRMIDHVSKYLFAPTEDAKRNLEEEMVYGEIYVTGNTVIDALDRYMGLA
HCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCHHHHEEEEEEEEECCHHHHHHHHHHCHH
EERSKEVLEKVPFDEFGVVTFHRAENVDNPQTLKDFVRILERSPIPLVYPVHPRTRKRLL
HHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
EFGLWDRVKRIPHLMITEPLGYLEFIGLLKNSKIVLSDSGGLQEEVTHPKIRKRIIVLRT
HHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCHHHHCCHHHHCEEEEEEE
STERPEAIKSGFAYVVGTNPVVVLATLERALNEGAPLPEASPFGDGKAGKRIVDVLERVG
CCCCCHHHHCCCEEEECCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]