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The map label for this gene is frdB [H]

Identifier: 156937239

GI number: 156937239

Start: 394830

End: 395789

Strand: Direct

Name: frdB [H]

Synonym: Igni_0445

Alternate gene names: 156937239

Gene position: 394830-395789 (Clockwise)

Preceding gene: 156937237

Following gene: 156937241

Centisome position: 30.43

GC content: 61.98

Gene sequence:

>960_bases
TTGCCCAAAGTAAAGTTCAAGGTAGCCCGGTACGACCCCGCCACTAAGGCATCTTGGTGGCAAGAGTACGAGGTGGAGGT
GGACAAGTACACCTCCGTAGCGGTCGCCTTGCAAAGGGTTAGGGAGGAGAAGGACCCCACCCTAGCTTACAGGCCGCTGT
GCAAGATGGGCGTCTGCGGGAACTGCGCGGTCAAGATAAACGGGAGGCCCGCGCTGGCTTGCTTGACCAACGCCCTGGAG
GCCGCAGAAGAGGGGAACGGGACTATAGTGGTCGAGCCCTTGGACAACATGCCGGTCGTGAGGGACCTAATAGTAGACAG
GTCGGACTTCGAGAGGAGGATGTTCTCCGTCAAGCCCTACCTAGTTCCTAAGGAGGAGGTCCTCAAGTCCGACAAGTGGT
ACCCCATGCTCCCGGCGGTGCAGATGGACTTGTGGAGCTCCGCCCAGTGCGTCTGGTGCGGGGTGTGCTACAGCGTCTGC
CCGGTAGCCAAGGTCAACGAGGAGTTCGCCGGGCCCCACGCGCTGGTCAAGGTGTACCGCTTCGCCTACGACCCCAGGGA
CGCCCTCGGGAGGGAGAGGGTGTACCTCAACGAGAAGAGCTTGTGGATGTGTGTGGCGTGCAAGAACTGCGGGACTTCGT
GTCCAAAGAACTTGAAGCACGGGCTTAGGTTCAAACGCATGAGGAACGACGACGTCAAGTCGCCGAGGAGCGAGTACGCG
GAGAAAGCGGTAAAGCACGTGATCGCTACCATAGCGAGCATAGCGAAGTACGGGAGGGCGGACGAGGTGGAGATCTTCAC
CTCCACCGGCCTGACCGAGGCGGTCGCGGACGCCTTGCCGAGGCTGGCCAGAGGGGGATGGAAGAGGAGGCCCTACAAGC
CCAAGCCCGGGGAGGCGGACCGCCGGGCAGTGGAGGCCTTCCGCGCGGCCGTGAGTGGGCTTTTAAAGGCGCGGGTCTAG

Upstream 100 bases:

>100_bases
CAGCTACCTTCAAGACGCGTTCCCGCGGGGCGGCTCGCCGGTCCCCTTTTTGAAGGGGAGAGACTAAAGGGAAGGGCTCA
GACCCTCCCTAGGGAGGGGC

Downstream 100 bases:

>100_bases
GTAAGACCCGCAAACTCCCCTTATATCTCTTTCATCGGCCTACCCCTCCGACGGGCGGAAGATGAAGTTCGTAGCTCGCG
TTTACCCCGAGAGGAACGAA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MPKVKFKVARYDPATKASWWQEYEVEVDKYTSVAVALQRVREEKDPTLAYRPLCKMGVCGNCAVKINGRPALACLTNALE
AAEEGNGTIVVEPLDNMPVVRDLIVDRSDFERRMFSVKPYLVPKEEVLKSDKWYPMLPAVQMDLWSSAQCVWCGVCYSVC
PVAKVNEEFAGPHALVKVYRFAYDPRDALGRERVYLNEKSLWMCVACKNCGTSCPKNLKHGLRFKRMRNDDVKSPRSEYA
EKAVKHVIATIASIAKYGRADEVEIFTSTGLTEAVADALPRLARGGWKRRPYKPKPGEADRRAVEAFRAAVSGLLKARV

Sequences:

>Translated_319_residues
MPKVKFKVARYDPATKASWWQEYEVEVDKYTSVAVALQRVREEKDPTLAYRPLCKMGVCGNCAVKINGRPALACLTNALE
AAEEGNGTIVVEPLDNMPVVRDLIVDRSDFERRMFSVKPYLVPKEEVLKSDKWYPMLPAVQMDLWSSAQCVWCGVCYSVC
PVAKVNEEFAGPHALVKVYRFAYDPRDALGRERVYLNEKSLWMCVACKNCGTSCPKNLKHGLRFKRMRNDDVKSPRSEYA
EKAVKHVIATIASIAKYGRADEVEIFTSTGLTEAVADALPRLARGGWKRRPYKPKPGEADRRAVEAFRAAVSGLLKARV
>Mature_318_residues
PKVKFKVARYDPATKASWWQEYEVEVDKYTSVAVALQRVREEKDPTLAYRPLCKMGVCGNCAVKINGRPALACLTNALEA
AEEGNGTIVVEPLDNMPVVRDLIVDRSDFERRMFSVKPYLVPKEEVLKSDKWYPMLPAVQMDLWSSAQCVWCGVCYSVCP
VAKVNEEFAGPHALVKVYRFAYDPRDALGRERVYLNEKSLWMCVACKNCGTSCPKNLKHGLRFKRMRNDDVKSPRSEYAE
KAVKHVIATIASIAKYGRADEVEIFTSTGLTEAVADALPRLARGGWKRRPYKPKPGEADRRAVEAFRAAVSGLLKARV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=223, Percent_Identity=33.6322869955157, Blast_Score=118, Evalue=6e-27,
Organism=Escherichia coli, GI1790596, Length=222, Percent_Identity=34.2342342342342, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786943, Length=222, Percent_Identity=31.5315315315315, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17533915, Length=220, Percent_Identity=29.5454545454545, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322987, Length=234, Percent_Identity=32.4786324786325, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17137106, Length=225, Percent_Identity=32, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24643156, Length=225, Percent_Identity=30.6666666666667, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 35901; Mature: 35770

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVKFKVARYDPATKASWWQEYEVEVDKYTSVAVALQRVREEKDPTLAYRPLCKMGVCG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
NCAVKINGRPALACLTNALEAAEEGNGTIVVEPLDNMPVVRDLIVDRSDFERRMFSVKPY
CCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCHHHHHHHHHHCCCC
LVPKEEVLKSDKWYPMLPAVQMDLWSSAQCVWCGVCYSVCPVAKVNEEFAGPHALVKVYR
CCCHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHH
FAYDPRDALGRERVYLNEKSLWMCVACKNCGTSCPKNLKHGLRFKRMRNDDVKSPRSEYA
HHCCCHHHHCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
EKAVKHVIATIASIAKYGRADEVEIFTSTGLTEAVADALPRLARGGWKRRPYKPKPGEAD
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
RRAVEAFRAAVSGLLKARV
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PKVKFKVARYDPATKASWWQEYEVEVDKYTSVAVALQRVREEKDPTLAYRPLCKMGVCG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
NCAVKINGRPALACLTNALEAAEEGNGTIVVEPLDNMPVVRDLIVDRSDFERRMFSVKPY
CCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCHHHHHHHHHHCCCC
LVPKEEVLKSDKWYPMLPAVQMDLWSSAQCVWCGVCYSVCPVAKVNEEFAGPHALVKVYR
CCCHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHH
FAYDPRDALGRERVYLNEKSLWMCVACKNCGTSCPKNLKHGLRFKRMRNDDVKSPRSEYA
HHCCCHHHHCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
EKAVKHVIATIASIAKYGRADEVEIFTSTGLTEAVADALPRLARGGWKRRPYKPKPGEAD
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
RRAVEAFRAAVSGLLKARV
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]